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MCRB vs DBVT vs REGN vs ABBV vs MRK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MCRB
Seres Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$74M
5Y Perf.-93.0%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-58.8%
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$73.68B
5Y Perf.+15.7%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$358.42B
5Y Perf.+118.7%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+45.9%

MCRB vs DBVT vs REGN vs ABBV vs MRK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MCRB logoMCRB
DBVT logoDBVT
REGN logoREGN
ABBV logoABBV
MRK logoMRK
IndustryBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$74M$1712.35T$73.68B$358.42B$277.34B
Revenue (TTM)$1M$0.00$14.92B$61.16B$64.93B
Net Income (TTM)$-47M$-168M$4.42B$4.23B$18.25B
Gross Margin16.0%84.5%70.2%74.2%
Operating Margin-76.4%24.3%26.7%41.1%
Forward P/E12.1x15.3x14.3x21.9x
Total Debt$83M$22M$2.71B$69.07B$50.53B
Cash & Equiv.$46M$194M$3.12B$5.23B$14.56B

MCRB vs DBVT vs REGN vs ABBV vs MRKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MCRB
DBVT
REGN
ABBV
MRK
StockMay 20May 26Return
Seres Therapeutics,… (MCRB)1007.0-93.0%
DBV Technologies S.… (DBVT)10041.2-58.8%
Regeneron Pharmaceu… (REGN)100115.7+15.7%
AbbVie Inc. (ABBV)100218.7+118.7%
Merck & Co., Inc. (MRK)100145.9+45.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: MCRB vs DBVT vs REGN vs ABBV vs MRK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABBV leads in 3 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. Seres Therapeutics, Inc. is the stronger pick specifically for valuation and capital efficiency. DBVT, REGN, and MRK also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
MCRB
Seres Therapeutics, Inc.
The Value Play

MCRB is the #2 pick in this set and the best alternative if value is your priority.

  • Lower P/E (12.1x vs 14.3x)
Best for: value
DBVT
DBV Technologies S.A.
The Momentum Pick

DBVT ranks third and is worth considering specifically for momentum.

  • +110.4% vs MCRB's -6.9%
Best for: momentum
REGN
Regeneron Pharmaceuticals, Inc.
The Growth Play

REGN is the clearest fit if your priority is growth exposure and sleep-well-at-night.

  • Rev growth 1.0%, EPS growth 8.2%, 3Y rev CAGR 5.6%
  • Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
  • 29.6% margin vs MCRB's -40.9%
Best for: growth exposure and sleep-well-at-night
ABBV
AbbVie Inc.
The Income Pick

ABBV carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 13 yrs, beta 0.34, yield 3.2%
  • 295.5% 10Y total return vs MRK's 166.5%
  • Beta 0.34, yield 3.2%, current ratio 0.67x
  • 8.6% revenue growth vs MCRB's -153.7%
Best for: income & stability and long-term compounding
MRK
Merck & Co., Inc.
The Value Pick

MRK is the clearest fit if your priority is valuation efficiency.

  • PEG 1.03 vs REGN's 2.43
  • 14.6% ROA vs DBVT's -89.0%
Best for: valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthABBV logoABBV8.6% revenue growth vs MCRB's -153.7%
ValueMCRB logoMCRBLower P/E (12.1x vs 14.3x)
Quality / MarginsREGN logoREGN29.6% margin vs MCRB's -40.9%
Stability / SafetyABBV logoABBVBeta 0.34 vs MCRB's 1.69
DividendsABBV logoABBV3.2% yield, 13-year raise streak, vs MRK's 2.9%, (2 stocks pay no dividend)
Momentum (1Y)DBVT logoDBVT+110.4% vs MCRB's -6.9%
Efficiency (ROA)MRK logoMRK14.6% ROA vs DBVT's -89.0%

MCRB vs DBVT vs REGN vs ABBV vs MRK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MCRBSeres Therapeutics, Inc.
FY 2019
License And Service
100.0%$27M
DBVTDBV Technologies S.A.

Segment breakdown not available.

REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M

MCRB vs DBVT vs REGN vs ABBV vs MRK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLREGNLAGGINGDBVT

Income & Cash Flow (Last 12 Months)

REGN leads this category, winning 3 of 6 comparable metrics.

MRK and DBVT operate at a comparable scale, with $64.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to MCRB's -40.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMCRB logoMCRBSeres Therapeutic…DBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.
RevenueTrailing 12 months$1M$0$14.9B$61.2B$64.9B
EBITDAEarnings before interest/tax-$83M-$112M$4.2B$24.5B$32.4B
Net IncomeAfter-tax profit-$47M-$168M$4.4B$4.2B$18.3B
Free Cash FlowCash after capex-$42M-$151M$4.2B$18.7B$12.4B
Gross MarginGross profit ÷ Revenue+16.0%+84.5%+70.2%+74.2%
Operating MarginEBIT ÷ Revenue-76.4%+24.3%+26.7%+41.1%
Net MarginNet income ÷ Revenue-40.9%+29.6%+6.9%+28.1%
FCF MarginFCF ÷ Revenue-36.9%+27.9%+30.6%+19.0%
Rev. Growth (YoY)Latest quarter vs prior year+19.0%+10.0%+4.5%
EPS Growth (YoY)Latest quarter vs prior year-155.5%+91.5%-7.2%+57.4%-19.6%
REGN leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

MRK leads this category, winning 3 of 7 comparable metrics.

At 12.1x trailing earnings, MCRB trades at a 86% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.73x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMCRB logoMCRBSeres Therapeutic…DBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.
Market CapShares × price$74M$1712.35T$73.7B$358.4B$277.3B
Enterprise ValueMkt cap + debt − cash$112M$1712.35T$73.3B$422.3B$313.3B
Trailing P/EPrice ÷ TTM EPS12.06x-0.76x17.09x85.50x15.42x
Forward P/EPrice ÷ next-FY EPS est.15.35x14.28x21.93x
PEG RatioP/E ÷ EPS growth rate2.70x0.73x
EV / EBITDAEnterprise value multiple17.78x14.96x10.68x
Price / SalesMarket cap ÷ Revenue94.25x5.14x5.86x4.27x
Price / BookPrice ÷ Book value/share1.55x0.66x2.46x5.35x
Price / FCFMarket cap ÷ FCF85.97x18.06x20.12x22.44x
MRK leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

REGN leads this category, winning 3 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to MCRB's 1.88x. On the Piotroski fundamental quality scale (0–9), MCRB scores 7/9 vs MRK's 4/9, reflecting strong financial health.

MetricMCRB logoMCRBSeres Therapeutic…DBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.
ROE (TTM)Return on equity-127.3%-130.2%+14.3%+62.1%+36.1%
ROA (TTM)Return on assets-34.5%-89.0%+11.1%+3.1%+14.6%
ROICReturn on invested capital-90.3%+8.9%+23.9%+22.0%
ROCEReturn on capital employed-86.4%-145.7%+10.2%+21.5%+23.8%
Piotroski ScoreFundamental quality 0–974564
Debt / EquityFinancial leverage1.88x0.13x0.09x0.96x
Net DebtTotal debt minus cash$37M-$172M-$412M$63.8B$36.0B
Cash & Equiv.Liquid assets$46M$194M$3.1B$5.2B$14.6B
Total DebtShort + long-term debt$83M$22M$2.7B$69.1B$50.5B
Interest CoverageEBIT ÷ Interest expense-189.82x108.44x3.28x19.68x
REGN leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ABBV leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $186 for MCRB. Over the past 12 months, DBVT leads with a +110.4% total return vs MCRB's -6.9%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs MCRB's -58.9% — a key indicator of consistent wealth creation.

MetricMCRB logoMCRBSeres Therapeutic…DBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.
YTD ReturnYear-to-date-49.0%+4.9%-8.5%-10.1%+6.3%
1-Year ReturnPast 12 months-6.9%+110.4%+27.1%+11.3%+46.1%
3-Year ReturnCumulative with dividends-93.1%+19.7%-5.1%+50.4%+2.9%
5-Year ReturnCumulative with dividends-98.1%-69.1%+43.6%+101.3%+70.2%
10-Year ReturnCumulative with dividends-98.5%-87.0%+90.0%+295.5%+166.5%
CAGR (3Y)Annualised 3-year return-58.9%+6.2%-1.7%+14.6%+0.9%
ABBV leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than MCRB's 1.69 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs MCRB's 25.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMCRB logoMCRBSeres Therapeutic…DBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.
Beta (5Y)Sensitivity to S&P 5001.69x1.26x0.81x0.34x0.48x
52-Week HighHighest price in past year$29.98$26.18$821.11$244.81$125.14
52-Week LowLowest price in past year$6.53$7.53$476.49$176.57$73.31
% of 52W HighCurrent price vs 52-week peak+25.8%+76.3%+86.4%+82.8%+89.7%
RSI (14)Momentum oscillator 0–10046.448.144.946.846.7
Avg Volume (50D)Average daily shares traded50K252K631K5.8M7.3M
Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.

Analyst consensus: MCRB as "Buy", DBVT as "Buy", REGN as "Buy", ABBV as "Buy", MRK as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs -83.8% for MCRB (target: $1). For income investors, ABBV offers the higher dividend yield at 3.24% vs REGN's 0.48%.

MetricMCRB logoMCRBSeres Therapeutic…DBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$1.25$46.33$865.68$256.64$129.31
# AnalystsCovering analysts1815484137
Dividend YieldAnnual dividend ÷ price+0.5%+3.2%+2.9%
Dividend StreakConsecutive years of raises011314
Dividend / ShareAnnual DPS$3.41$6.57$3.26
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+5.4%+0.3%+1.8%
Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.
Key Takeaway

REGN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). MRK leads in 1 (Valuation Metrics). 2 tied.

Best OverallRegeneron Pharmaceuticals, … (REGN)Leads 2 of 6 categories
Loading custom metrics...

MCRB vs DBVT vs REGN vs ABBV vs MRK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MCRB or DBVT or REGN or ABBV or MRK a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Seres Therapeutics, Inc. (MCRB) offers the better valuation at 12. 1x trailing P/E, making it the more compelling value choice. Analysts rate Seres Therapeutics, Inc. (MCRB) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MCRB or DBVT or REGN or ABBV or MRK?

On trailing P/E, Seres Therapeutics, Inc.

(MCRB) is the cheapest at 12. 1x versus AbbVie Inc. at 85. 5x. On forward P/E, AbbVie Inc. is actually cheaper at 14. 3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Merck & Co. , Inc. wins at 1. 03x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — MCRB or DBVT or REGN or ABBV or MRK?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +101. 3%, compared to -98. 1% for Seres Therapeutics, Inc. (MCRB). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus MCRB's -98. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MCRB or DBVT or REGN or ABBV or MRK?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 34β versus Seres Therapeutics, Inc. 's 1. 69β — meaning MCRB is approximately 400% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 188% for Seres Therapeutics, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — MCRB or DBVT or REGN or ABBV or MRK?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Seres Therapeutics, Inc. grew EPS 103. 4% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MCRB or DBVT or REGN or ABBV or MRK?

Seres Therapeutics, Inc.

(MCRB) is the more profitable company, earning 721. 9% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 721. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus -119. 1% for MCRB. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MCRB or DBVT or REGN or ABBV or MRK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Merck & Co. , Inc. (MRK) is the more undervalued stock at a PEG of 1. 03x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, AbbVie Inc. (ABBV) trades at 14. 3x forward P/E versus 21. 9x for Merck & Co. , Inc. — 7. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.

08

Which pays a better dividend — MCRB or DBVT or REGN or ABBV or MRK?

In this comparison, ABBV (3.

2% yield), MRK (2. 9% yield), REGN (0. 5% yield) pay a dividend. MCRB, DBVT do not pay a meaningful dividend and should not be held primarily for income.

09

Is MCRB or DBVT or REGN or ABBV or MRK better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Seres Therapeutics, Inc. (MCRB) carries a higher beta of 1. 69 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABBV: +295. 5%, MCRB: -98. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MCRB and DBVT and REGN and ABBV and MRK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: MCRB is a small-cap deep-value stock; DBVT is a mega-cap quality compounder stock; REGN is a mid-cap deep-value stock; ABBV is a large-cap income-oriented stock; MRK is a large-cap deep-value stock. ABBV, MRK pay a dividend while MCRB, DBVT, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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