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Stock Comparison

MLTX vs UCB vs SFNC vs HOMB

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MLTX
MoonLake Immunotherapeutics

Biotechnology

HealthcareNASDAQ • CH
Market Cap$1.23B
5Y Perf.+67.6%
UCB
United Community Banks, Inc.

Banks - Regional

Financial ServicesNYSE • US
Market Cap$4.02B
5Y Perf.+60.3%
SFNC
Simmons First National Corporation

Banks - Regional

Financial ServicesNASDAQ • US
Market Cap$3.09B
5Y Perf.+25.7%
HOMB
Home Bancshares, Inc.

Banks - Regional

Financial ServicesNYSE • US
Market Cap$5.29B
5Y Perf.+61.8%

MLTX vs UCB vs SFNC vs HOMB — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MLTX logoMLTX
UCB logoUCB
SFNC logoSFNC
HOMB logoHOMB
IndustryBiotechnologyBanks - RegionalBanks - RegionalBanks - Regional
Market Cap$1.23B$4.02B$3.09B$5.29B
Revenue (TTM)$0.00$1.54B$627M$1.45B
Net Income (TTM)$-227M$328M$-398M$458M
Gross Margin66.0%5.8%65.6%
Operating Margin27.5%-84.2%36.0%
Forward P/E11.2x10.3x10.8x
Total Debt$76M$205M$641M$1.20B
Cash & Equiv.$335M$203M$380M$910M

MLTX vs UCB vs SFNC vs HOMBLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MLTX
UCB
SFNC
HOMB
StockOct 20May 26Return
MoonLake Immunother… (MLTX)100167.6+67.6%
United Community Ba… (UCB)100160.3+60.3%
Simmons First Natio… (SFNC)100125.7+25.7%
Home Bancshares, In… (HOMB)100161.8+61.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: MLTX vs UCB vs SFNC vs HOMB

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HOMB leads in 4 of 7 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Simmons First National Corporation is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. UCB also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
MLTX
MoonLake Immunotherapeutics
The Secondary Option

MLTX lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
UCB
United Community Banks, Inc.
The Banking Pick

UCB is the clearest fit if your priority is long-term compounding and sleep-well-at-night.

  • 109.0% 10Y total return vs MLTX's 64.0%
  • Lower volatility, beta 1.02, Low D/E 5.6%, current ratio 0.17x
  • PEG 1.72 vs HOMB's 3.55
  • +23.3% vs MLTX's -54.3%
Best for: long-term compounding and sleep-well-at-night
SFNC
Simmons First National Corporation
The Banking Pick

SFNC is the #2 pick in this set and the best alternative if defensive is your priority.

  • Beta 1.02, yield 4.0%, current ratio 0.86x
  • Lower P/E (10.3x vs 10.8x)
  • 4.0% yield, 6-year raise streak, vs HOMB's 2.8%, (1 stock pays no dividend)
Best for: defensive
HOMB
Home Bancshares, Inc.
The Banking Pick

HOMB carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 21 yrs, beta 0.82, yield 2.8%
  • Rev growth 9.5%, EPS growth 3.6%
  • NIM 3.8% vs SFNC's 2.9%
  • 9.5% NII/revenue growth vs MLTX's -92.2%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthHOMB logoHOMB9.5% NII/revenue growth vs MLTX's -92.2%
ValueSFNC logoSFNCLower P/E (10.3x vs 10.8x)
Quality / MarginsHOMB logoHOMB27.7% margin vs SFNC's -63.4%
Stability / SafetyHOMB logoHOMBBeta 0.82 vs MLTX's 1.17
DividendsSFNC logoSFNC4.0% yield, 6-year raise streak, vs HOMB's 2.8%, (1 stock pays no dividend)
Momentum (1Y)UCB logoUCB+23.3% vs MLTX's -54.3%
Efficiency (ROA)HOMB logoHOMB2.0% ROA vs MLTX's -53.6%, ROIC 7.2% vs -114.2%

MLTX vs UCB vs SFNC vs HOMB — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MLTXMoonLake Immunotherapeutics
FY 2025
License
100.0%$300M
UCBUnited Community Banks, Inc.

Segment breakdown not available.

SFNCSimmons First National Corporation
FY 2025
Deposit Account
36.8%$51M
Fiduciary and Trust
28.5%$39M
Credit and Debit Card
24.7%$34M
Mortgage Loans
5.9%$8M
Financial Service, Other
4.1%$6M
HOMBHome Bancshares, Inc.
FY 2024
Financial Service, Other
52.3%$43M
Deposit Account
47.7%$39M

MLTX vs UCB vs SFNC vs HOMB — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLUCBLAGGINGHOMB

Income & Cash Flow (Last 12 Months)

Evenly matched — SFNC and HOMB each lead in 2 of 5 comparable metrics.

UCB and MLTX operate at a comparable scale, with $1.5B and $0 in trailing revenue. HOMB is the more profitable business, keeping 27.7% of every revenue dollar as net income compared to SFNC's -63.4%.

MetricMLTX logoMLTXMoonLake Immunoth…UCB logoUCBUnited Community …SFNC logoSFNCSimmons First Nat…HOMB logoHOMBHome Bancshares, …
RevenueTrailing 12 months$0$1.5B$627M$1.5B
EBITDAEarnings before interest/tax-$242M$457M-$497M$601M
Net IncomeAfter-tax profit-$227M$328M-$398M$458M
Free Cash FlowCash after capex-$196M$408M$755M$354M
Gross MarginGross profit ÷ Revenue+66.0%+5.8%+65.6%
Operating MarginEBIT ÷ Revenue+27.5%-84.2%+36.0%
Net MarginNet income ÷ Revenue+21.4%-63.4%+27.7%
FCF MarginFCF ÷ Revenue+26.5%+71.7%+29.1%
Rev. Growth (YoY)Latest quarter vs prior year
EPS Growth (YoY)Latest quarter vs prior year-29.2%+16.4%+42.1%+26.0%
Evenly matched — SFNC and HOMB each lead in 2 of 5 comparable metrics.

Valuation Metrics

SFNC leads this category, winning 4 of 7 comparable metrics.

At 12.8x trailing earnings, UCB trades at a 4% valuation discount to HOMB's 13.4x P/E. Adjusting for growth (PEG ratio), UCB offers better value at 1.96x vs HOMB's 4.39x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMLTX logoMLTXMoonLake Immunoth…UCB logoUCBUnited Community …SFNC logoSFNCSimmons First Nat…HOMB logoHOMBHome Bancshares, …
Market CapShares × price$1.2B$4.0B$3.1B$5.3B
Enterprise ValueMkt cap + debt − cash$969M$4.0B$3.4B$5.6B
Trailing P/EPrice ÷ TTM EPS-4.87x12.81x-7.24x13.36x
Forward P/EPrice ÷ next-FY EPS est.11.22x10.35x10.82x
PEG RatioP/E ÷ EPS growth rate1.96x4.39x
EV / EBITDAEnterprise value multiple8.80x10.12x
Price / SalesMarket cap ÷ Revenue2.61x4.93x3.64x
Price / BookPrice ÷ Book value/share3.64x1.12x0.84x1.36x
Price / FCFMarket cap ÷ FCF9.85x6.88x12.53x
SFNC leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — UCB and HOMB each lead in 4 of 9 comparable metrics.

HOMB delivers a 10.9% return on equity — every $100 of shareholder capital generates $11 in annual profit, vs $-75 for MLTX. UCB carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to HOMB's 0.30x. On the Piotroski fundamental quality scale (0–9), UCB scores 7/9 vs MLTX's 1/9, reflecting strong financial health.

MetricMLTX logoMLTXMoonLake Immunoth…UCB logoUCBUnited Community …SFNC logoSFNCSimmons First Nat…HOMB logoHOMBHome Bancshares, …
ROE (TTM)Return on equity-74.7%+9.1%-11.6%+10.9%
ROA (TTM)Return on assets-53.6%+1.2%-1.6%+2.0%
ROICReturn on invested capital-114.2%+8.2%-9.1%+7.2%
ROCEReturn on capital employed-58.7%+10.3%-4.2%+9.8%
Piotroski ScoreFundamental quality 0–91747
Debt / EquityFinancial leverage0.25x0.06x0.19x0.30x
Net DebtTotal debt minus cash-$259M$3M$261M$292M
Cash & Equiv.Liquid assets$335M$203M$380M$910M
Total DebtShort + long-term debt$76M$205M$641M$1.2B
Interest CoverageEBIT ÷ Interest expense-31.31x0.89x-1.01x1.44x
Evenly matched — UCB and HOMB each lead in 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

UCB leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in MLTX five years ago would be worth $16,863 today (with dividends reinvested), compared to $8,461 for SFNC. Over the past 12 months, UCB leads with a +23.3% total return vs MLTX's -54.3%. The 3-year compound annual growth rate (CAGR) favors UCB at 18.9% vs MLTX's -14.0% — a key indicator of consistent wealth creation.

MetricMLTX logoMLTXMoonLake Immunoth…UCB logoUCBUnited Community …SFNC logoSFNCSimmons First Nat…HOMB logoHOMBHome Bancshares, …
YTD ReturnYear-to-date+43.9%+7.5%+14.6%-3.0%
1-Year ReturnPast 12 months-54.3%+23.3%+16.7%-1.9%
3-Year ReturnCumulative with dividends-36.4%+68.2%+53.4%+42.0%
5-Year ReturnCumulative with dividends+68.6%+9.7%-15.4%+6.6%
10-Year ReturnCumulative with dividends+64.0%+109.0%+25.2%+58.2%
CAGR (3Y)Annualised 3-year return-14.0%+18.9%+15.3%+12.4%
UCB leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — SFNC and HOMB each lead in 1 of 2 comparable metrics.

HOMB is the less volatile stock with a 0.82 beta — it tends to amplify market swings less than MLTX's 1.17 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. SFNC currently trades 96.3% from its 52-week high vs MLTX's 27.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMLTX logoMLTXMoonLake Immunoth…UCB logoUCBUnited Community …SFNC logoSFNCSimmons First Nat…HOMB logoHOMBHome Bancshares, …
Beta (5Y)Sensitivity to S&P 5001.17x1.02x1.02x0.82x
52-Week HighHighest price in past year$62.75$36.77$22.18$30.83
52-Week LowLowest price in past year$5.95$27.23$17.00$25.68
% of 52W HighCurrent price vs 52-week peak+27.4%+91.3%+96.3%+87.1%
RSI (14)Momentum oscillator 0–10053.057.262.350.3
Avg Volume (50D)Average daily shares traded957K825K1.2M1.4M
Evenly matched — SFNC and HOMB each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — SFNC and HOMB each lead in 1 of 2 comparable metrics.

Analyst consensus: MLTX as "Buy", UCB as "Hold", SFNC as "Buy", HOMB as "Hold". Consensus price targets imply 46.8% upside for MLTX (target: $25) vs 6.1% for SFNC (target: $23). For income investors, SFNC offers the higher dividend yield at 4.00% vs HOMB's 2.79%.

MetricMLTX logoMLTXMoonLake Immunoth…UCB logoUCBUnited Community …SFNC logoSFNCSimmons First Nat…HOMB logoHOMBHome Bancshares, …
Analyst RatingConsensus buy/hold/sellBuyHoldBuyHold
Price TargetConsensus 12-month target$25.25$39.50$22.67$32.00
# AnalystsCovering analysts187919
Dividend YieldAnnual dividend ÷ price+2.9%+4.0%+2.8%
Dividend StreakConsecutive years of raises9621
Dividend / ShareAnnual DPS$0.97$0.85$0.75
Buyback YieldShare repurchases ÷ mkt cap0.0%+3.4%0.0%+1.6%
Evenly matched — SFNC and HOMB each lead in 1 of 2 comparable metrics.
Key Takeaway

SFNC leads in 1 of 6 categories (Valuation Metrics). UCB leads in 1 (Total Returns). 4 tied.

Best OverallUnited Community Banks, Inc. (UCB)Leads 1 of 6 categories
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MLTX vs UCB vs SFNC vs HOMB: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MLTX or UCB or SFNC or HOMB a better buy right now?

For growth investors, Home Bancshares, Inc.

(HOMB) is the stronger pick with 9. 5% revenue growth year-over-year, versus -56. 7% for Simmons First National Corporation (SFNC). United Community Banks, Inc. (UCB) offers the better valuation at 12. 8x trailing P/E (11. 2x forward), making it the more compelling value choice. Analysts rate MoonLake Immunotherapeutics (MLTX) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MLTX or UCB or SFNC or HOMB?

On trailing P/E, United Community Banks, Inc.

(UCB) is the cheapest at 12. 8x versus Home Bancshares, Inc. at 13. 4x. On forward P/E, Simmons First National Corporation is actually cheaper at 10. 3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: United Community Banks, Inc. wins at 1. 72x versus Home Bancshares, Inc. 's 3. 55x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — MLTX or UCB or SFNC or HOMB?

Over the past 5 years, MoonLake Immunotherapeutics (MLTX) delivered a total return of +68.

6%, compared to -15. 4% for Simmons First National Corporation (SFNC). Over 10 years, the gap is even starker: UCB returned +109. 0% versus SFNC's +25. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MLTX or UCB or SFNC or HOMB?

By beta (market sensitivity over 5 years), Home Bancshares, Inc.

(HOMB) is the lower-risk stock at 0. 82β versus MoonLake Immunotherapeutics's 1. 17β — meaning MLTX is approximately 44% more volatile than HOMB relative to the S&P 500. On balance sheet safety, United Community Banks, Inc. (UCB) carries a lower debt/equity ratio of 6% versus 30% for Home Bancshares, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — MLTX or UCB or SFNC or HOMB?

By revenue growth (latest reported year), Home Bancshares, Inc.

(HOMB) is pulling ahead at 9. 5% versus -56. 7% for Simmons First National Corporation (SFNC). On earnings-per-share growth, the picture is similar: United Community Banks, Inc. grew EPS 28. 4% year-over-year, compared to -343. 8% for Simmons First National Corporation. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MLTX or UCB or SFNC or HOMB?

Home Bancshares, Inc.

(HOMB) is the more profitable company, earning 27. 7% net margin versus -63. 4% for Simmons First National Corporation — meaning it keeps 27. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HOMB leads at 36. 0% versus -84. 2% for SFNC. At the gross margin level — before operating expenses — UCB leads at 66. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MLTX or UCB or SFNC or HOMB more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, United Community Banks, Inc. (UCB) is the more undervalued stock at a PEG of 1. 72x versus Home Bancshares, Inc. 's 3. 55x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, Simmons First National Corporation (SFNC) trades at 10. 3x forward P/E versus 11. 2x for United Community Banks, Inc. — 0. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MLTX: 46. 8% to $25. 25.

08

Which pays a better dividend — MLTX or UCB or SFNC or HOMB?

In this comparison, SFNC (4.

0% yield), UCB (2. 9% yield), HOMB (2. 8% yield) pay a dividend. MLTX does not pay a meaningful dividend and should not be held primarily for income.

09

Is MLTX or UCB or SFNC or HOMB better for a retirement portfolio?

For long-horizon retirement investors, Home Bancshares, Inc.

(HOMB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 82), 2. 8% yield). Both have compounded well over 10 years (HOMB: +58. 2%, MLTX: +64. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MLTX and UCB and SFNC and HOMB?

These companies operate in different sectors (MLTX (Healthcare) and UCB (Financial Services) and SFNC (Financial Services) and HOMB (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: MLTX is a small-cap quality compounder stock; UCB is a small-cap deep-value stock; SFNC is a small-cap income-oriented stock; HOMB is a small-cap deep-value stock. UCB, SFNC, HOMB pay a dividend while MLTX does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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MLTX

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  • Sector: Healthcare
  • Market Cap > $100B
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UCB

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  • Sector: Financial Services
  • Market Cap > $100B
  • Net Margin > 12%
  • Dividend Yield > 1.1%
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SFNC

Income & Dividend Stock

  • Sector: Financial Services
  • Market Cap > $100B
  • Dividend Yield > 1.5%
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HOMB

Dividend Mega-Cap Quality

  • Sector: Financial Services
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 16%
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