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Stock Comparison

MPLT vs ACNB vs CZWI vs PTGX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MPLT
MapLight Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • USA
Market Cap$1.33B
5Y Perf.+10.2%
ACNB
ACNB Corporation

Banks - Regional

Financial ServicesNASDAQ • US
Market Cap$544M
5Y Perf.+109.5%
CZWI
Citizens Community Bancorp, Inc.

Banks - Regional

Financial ServicesNASDAQ • US
Market Cap$202M
5Y Perf.+180.0%
PTGX
Protagonist Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.79B
5Y Perf.+518.1%

MPLT vs ACNB vs CZWI vs PTGX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MPLT logoMPLT
ACNB logoACNB
CZWI logoCZWI
PTGX logoPTGX
IndustryBiotechnologyBanks - RegionalBanks - RegionalBiotechnology
Market Cap$1.33B$544M$202M$6.79B
Revenue (TTM)$0.00$170M$90M$18M
Net Income (TTM)$-103M$37M$14M$-115M
Gross Margin73.7%54.7%100.0%
Operating Margin27.3%7.0%-8.1%
Forward P/E9.6x11.3x25.7x
Total Debt$7M$329M$52M$10M
Cash & Equiv.$38M$21M$119M$128M

MPLT vs ACNB vs CZWI vs PTGXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MPLT
ACNB
CZWI
PTGX
StockMay 20May 26Return
ACNB Corporation (ACNB)100209.5+109.5%
Citizens Community … (CZWI)100280.0+180.0%
Protagonist Therape… (PTGX)100618.1+518.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: MPLT vs ACNB vs CZWI vs PTGX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ACNB leads in 5 of 7 categories, making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Protagonist Therapeutics, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
MPLT
MapLight Therapeutics, Inc.
The Specific-Use Pick

MPLT plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
ACNB
ACNB Corporation
The Banking Pick

ACNB carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 8 yrs, beta 0.68, yield 2.7%
  • Rev growth 28.9%, EPS growth -3.5%
  • PEG 0.87 vs CZWI's 2.23
  • NIM 3.8% vs CZWI's 2.9%
Best for: income & stability and growth exposure
CZWI
Citizens Community Bancorp, Inc.
The Banking Pick

CZWI is the clearest fit if your priority is defensive.

  • Beta 0.45, yield 1.8%, current ratio 3015.31x
Best for: defensive
PTGX
Protagonist Therapeutics, Inc.
The Long-Run Compounder

PTGX is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.

  • 8.0% 10Y total return vs ACNB's 179.5%
  • Lower volatility, beta 0.23, Low D/E 1.7%, current ratio 12.71x
  • Beta 0.23 vs ACNB's 0.68, lower leverage
  • +141.1% vs ACNB's +22.7%
Best for: long-term compounding and sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthACNB logoACNB28.9% NII/revenue growth vs PTGX's -89.4%
ValueACNB logoACNBLower P/E (9.6x vs 25.7x)
Quality / MarginsACNB logoACNB21.7% margin vs PTGX's -6.5%
Stability / SafetyPTGX logoPTGXBeta 0.23 vs ACNB's 0.68, lower leverage
DividendsACNB logoACNB2.7% yield, 8-year raise streak, vs CZWI's 1.8%, (2 stocks pay no dividend)
Momentum (1Y)PTGX logoPTGX+141.1% vs ACNB's +22.7%
Efficiency (ROA)ACNB logoACNB1.1% ROA vs MPLT's -69.7%, ROIC 5.3% vs -153.7%

MPLT vs ACNB vs CZWI vs PTGX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MPLTMapLight Therapeutics, Inc.

Segment breakdown not available.

ACNBACNB Corporation
FY 2025
Mortgage Banking
29.0%$5M
Deposit Account
26.7%$5M
Fiduciary and Trust
24.7%$4M
ATM Service Charges and Debit Card Transactions
19.6%$4M
CZWICitizens Community Bancorp, Inc.
FY 2025
Reportable Segment
100.0%$99M
PTGXProtagonist Therapeutics, Inc.
FY 2024
Development Services
100.0%$15M

MPLT vs ACNB vs CZWI vs PTGX — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLACNBLAGGINGCZWI

Income & Cash Flow (Last 12 Months)

ACNB leads this category, winning 3 of 5 comparable metrics.

ACNB and MPLT operate at a comparable scale, with $170M and $0 in trailing revenue. ACNB is the more profitable business, keeping 21.7% of every revenue dollar as net income compared to PTGX's -6.5%.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…
RevenueTrailing 12 months$0$170M$90M$18M
EBITDAEarnings before interest/tax-$108M$53M$9M-$141M
Net IncomeAfter-tax profit-$103M$37M$14M-$115M
Free Cash FlowCash after capex-$113M$51M$11M-$116M
Gross MarginGross profit ÷ Revenue+73.7%+54.7%+100.0%
Operating MarginEBIT ÷ Revenue+27.3%+7.0%-8.1%
Net MarginNet income ÷ Revenue+21.7%+16.0%-6.5%
FCF MarginFCF ÷ Revenue+30.9%+11.5%-6.6%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%
EPS Growth (YoY)Latest quarter vs prior year+35.1%+63.0%+126.3%
ACNB leads this category, winning 3 of 5 comparable metrics.

Valuation Metrics

Evenly matched — ACNB and CZWI each lead in 3 of 7 comparable metrics.

At 14.3x trailing earnings, CZWI trades at a 2% valuation discount to ACNB's 14.6x P/E. Adjusting for growth (PEG ratio), ACNB offers better value at 1.32x vs CZWI's 2.83x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…
Market CapShares × price$1.3B$544M$202M$6.8B
Enterprise ValueMkt cap + debt − cash$1.3B$853M$134M$6.7B
Trailing P/EPrice ÷ TTM EPS-15.66x14.61x14.34x-51.49x
Forward P/EPrice ÷ next-FY EPS est.9.65x11.31x25.74x
PEG RatioP/E ÷ EPS growth rate1.32x2.83x
EV / EBITDAEnterprise value multiple16.03x15.12x
Price / SalesMarket cap ÷ Revenue3.20x2.24x147.52x
Price / BookPrice ÷ Book value/share10.53x1.29x1.08x10.92x
Price / FCFMarket cap ÷ FCF10.36x19.41x121.04x
Evenly matched — ACNB and CZWI each lead in 3 of 7 comparable metrics.

Profitability & Efficiency

ACNB leads this category, winning 5 of 9 comparable metrics.

ACNB delivers a 9.2% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-2 for MPLT. PTGX carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to ACNB's 0.78x. On the Piotroski fundamental quality scale (0–9), CZWI scores 6/9 vs PTGX's 4/9, reflecting solid financial health.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…
ROE (TTM)Return on equity-2.1%+9.2%+7.8%-17.8%
ROA (TTM)Return on assets-69.7%+1.1%+0.8%-16.5%
ROICReturn on invested capital-153.7%+5.3%+2.0%-21.8%
ROCEReturn on capital employed-83.9%+2.5%+0.6%-23.9%
Piotroski ScoreFundamental quality 0–94564
Debt / EquityFinancial leverage0.06x0.78x0.28x0.02x
Net DebtTotal debt minus cash-$32M$308M-$67M-$118M
Cash & Equiv.Liquid assets$38M$21M$119M$128M
Total DebtShort + long-term debt$7M$329M$52M$10M
Interest CoverageEBIT ÷ Interest expense1.16x0.16x
ACNB leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

PTGX leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in PTGX five years ago would be worth $34,641 today (with dividends reinvested), compared to $16,263 for MPLT. Over the past 12 months, PTGX leads with a +141.1% total return vs ACNB's +22.7%. The 3-year compound annual growth rate (CAGR) favors PTGX at 59.6% vs MPLT's 17.6% — a key indicator of consistent wealth creation.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…
YTD ReturnYear-to-date+62.6%+12.1%+21.3%+21.1%
1-Year ReturnPast 12 months+62.6%+22.7%+40.9%+141.1%
3-Year ReturnCumulative with dividends+62.6%+91.0%+174.8%+306.4%
5-Year ReturnCumulative with dividends+62.6%+105.4%+69.0%+246.4%
10-Year ReturnCumulative with dividends+62.6%+179.5%+154.0%+802.1%
CAGR (3Y)Annualised 3-year return+17.6%+24.1%+40.1%+59.6%
PTGX leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

PTGX leads this category, winning 2 of 2 comparable metrics.

PTGX is the less volatile stock with a 0.23 beta — it tends to amplify market swings less than ACNB's 0.68 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PTGX currently trades 97.9% from its 52-week high vs MPLT's 88.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…
Beta (5Y)Sensitivity to S&P 5000.69x0.50x0.20x
52-Week HighHighest price in past year$33.28$53.93$22.62$107.84
52-Week LowLowest price in past year$16.34$40.15$12.83$43.20
% of 52W HighCurrent price vs 52-week peak+88.0%+97.5%+92.5%+97.9%
RSI (14)Momentum oscillator 0–10059.257.257.954.8
Avg Volume (50D)Average daily shares traded264K62K38K726K
PTGX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

ACNB leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: ACNB as "Buy", CZWI as "Buy", PTGX as "Buy". Consensus price targets imply 15.4% upside for MPLT (target: $34) vs 9.3% for PTGX (target: $115). For income investors, ACNB offers the higher dividend yield at 2.66% vs CZWI's 1.77%.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$33.80$58.00$115.40
# AnalystsCovering analysts2226
Dividend YieldAnnual dividend ÷ price+2.7%+1.8%
Dividend StreakConsecutive years of raises87
Dividend / ShareAnnual DPS$1.40$0.37
Buyback YieldShare repurchases ÷ mkt cap0.0%+2.1%+3.1%0.0%
ACNB leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ACNB leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PTGX leads in 2 (Total Returns, Risk & Volatility). 1 tied.

Best OverallACNB Corporation (ACNB)Leads 3 of 6 categories
Loading custom metrics...

MPLT vs ACNB vs CZWI vs PTGX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MPLT or ACNB or CZWI or PTGX a better buy right now?

For growth investors, ACNB Corporation (ACNB) is the stronger pick with 28.

9% revenue growth year-over-year, versus -89. 4% for Protagonist Therapeutics, Inc. (PTGX). Citizens Community Bancorp, Inc. (CZWI) offers the better valuation at 14. 3x trailing P/E (11. 3x forward), making it the more compelling value choice. Analysts rate ACNB Corporation (ACNB) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MPLT or ACNB or CZWI or PTGX?

On trailing P/E, Citizens Community Bancorp, Inc.

(CZWI) is the cheapest at 14. 3x versus ACNB Corporation at 14. 6x. On forward P/E, ACNB Corporation is actually cheaper at 9. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: ACNB Corporation wins at 0. 87x versus Citizens Community Bancorp, Inc. 's 2. 23x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — MPLT or ACNB or CZWI or PTGX?

Over the past 5 years, Protagonist Therapeutics, Inc.

(PTGX) delivered a total return of +246. 4%, compared to +62. 6% for MapLight Therapeutics, Inc. (MPLT). Over 10 years, the gap is even starker: PTGX returned +773. 3% versus MPLT's +59. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MPLT or ACNB or CZWI or PTGX?

By beta (market sensitivity over 5 years), Protagonist Therapeutics, Inc.

(PTGX) is the lower-risk stock at 0. 20β versus ACNB Corporation's 0. 69β — meaning ACNB is approximately 246% more volatile than PTGX relative to the S&P 500. On balance sheet safety, Protagonist Therapeutics, Inc. (PTGX) carries a lower debt/equity ratio of 2% versus 78% for ACNB Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — MPLT or ACNB or CZWI or PTGX?

By revenue growth (latest reported year), ACNB Corporation (ACNB) is pulling ahead at 28.

9% versus -89. 4% for Protagonist Therapeutics, Inc. (PTGX). On earnings-per-share growth, the picture is similar: Citizens Community Bancorp, Inc. grew EPS 9. 0% year-over-year, compared to -148. 5% for Protagonist Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MPLT or ACNB or CZWI or PTGX?

ACNB Corporation (ACNB) is the more profitable company, earning 21.

7% net margin versus -282. 8% for Protagonist Therapeutics, Inc. — meaning it keeps 21. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ACNB leads at 27. 3% versus -343. 6% for PTGX. At the gross margin level — before operating expenses — PTGX leads at 97. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MPLT or ACNB or CZWI or PTGX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, ACNB Corporation (ACNB) is the more undervalued stock at a PEG of 0. 87x versus Citizens Community Bancorp, Inc. 's 2. 23x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, ACNB Corporation (ACNB) trades at 9. 6x forward P/E versus 25. 7x for Protagonist Therapeutics, Inc. — 16. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MPLT: 15. 4% to $33. 80.

08

Which pays a better dividend — MPLT or ACNB or CZWI or PTGX?

In this comparison, ACNB (2.

7% yield), CZWI (1. 8% yield) pay a dividend. MPLT, PTGX do not pay a meaningful dividend and should not be held primarily for income.

09

Is MPLT or ACNB or CZWI or PTGX better for a retirement portfolio?

For long-horizon retirement investors, Protagonist Therapeutics, Inc.

(PTGX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 20), +773. 3% 10Y return). Both have compounded well over 10 years (PTGX: +773. 3%, MPLT: +59. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MPLT and ACNB and CZWI and PTGX?

These companies operate in different sectors (MPLT (Healthcare) and ACNB (Financial Services) and CZWI (Financial Services) and PTGX (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: MPLT is a small-cap quality compounder stock; ACNB is a small-cap high-growth stock; CZWI is a small-cap deep-value stock; PTGX is a small-cap quality compounder stock. ACNB, CZWI pay a dividend while MPLT, PTGX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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