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Stock Comparison

MPLT vs ACNB vs CZWI vs PTGX vs NBTB

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MPLT
MapLight Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • USA
Market Cap$1.30B
5Y Perf.+9.8%
ACNB
ACNB Corporation

Banks - Regional

Financial ServicesNASDAQ • US
Market Cap$539M
5Y Perf.+109.5%
CZWI
Citizens Community Bancorp, Inc.

Banks - Regional

Financial ServicesNASDAQ • US
Market Cap$198M
5Y Perf.+180.0%
PTGX
Protagonist Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.57B
5Y Perf.+518.1%
NBTB
NBT Bancorp Inc.

Banks - Regional

Financial ServicesNASDAQ • US
Market Cap$2.30B
5Y Perf.+40.8%

MPLT vs ACNB vs CZWI vs PTGX vs NBTB — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MPLT logoMPLT
ACNB logoACNB
CZWI logoCZWI
PTGX logoPTGX
NBTB logoNBTB
IndustryBiotechnologyBanks - RegionalBanks - RegionalBiotechnologyBanks - Regional
Market Cap$1.30B$539M$198M$6.57B$2.30B
Revenue (TTM)$0.00$170M$90M$18M$867M
Net Income (TTM)$-103M$37M$14M$-115M$169M
Gross Margin73.7%54.7%100.0%72.1%
Operating Margin27.3%7.0%-8.1%25.3%
Forward P/E9.6x11.3x25.7x10.6x
Total Debt$7M$329M$52M$10M$327M
Cash & Equiv.$38M$21M$119M$128M$185M

MPLT vs ACNB vs CZWI vs PTGX vs NBTBLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MPLT
ACNB
CZWI
PTGX
NBTB
StockMay 20May 26Return
ACNB Corporation (ACNB)100209.5+109.5%
Citizens Community … (CZWI)100280.0+180.0%
Protagonist Therape… (PTGX)100618.1+518.1%
NBT Bancorp Inc. (NBTB)100140.8+40.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: MPLT vs ACNB vs CZWI vs PTGX vs NBTB

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ACNB leads in 4 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Protagonist Therapeutics, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. NBTB also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
MPLT
MapLight Therapeutics, Inc.
The Healthcare Pick

MPLT lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ACNB
ACNB Corporation
The Banking Pick

ACNB carries the broadest edge in this set and is the clearest fit for growth exposure and valuation efficiency.

  • Rev growth 28.9%, EPS growth -3.5%
  • PEG 0.87 vs CZWI's 2.23
  • NIM 3.8% vs CZWI's 2.9%
  • 28.9% NII/revenue growth vs PTGX's -89.4%
Best for: growth exposure and valuation efficiency
CZWI
Citizens Community Bancorp, Inc.
The Banking Pick

CZWI is the clearest fit if your priority is defensive.

  • Beta 0.50, yield 1.8%, current ratio 3015.31x
Best for: defensive
PTGX
Protagonist Therapeutics, Inc.
The Long-Run Compounder

PTGX is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.

  • 7.7% 10Y total return vs ACNB's 177.0%
  • Lower volatility, beta 0.20, Low D/E 1.7%, current ratio 12.71x
  • Beta 0.20 vs NBTB's 0.85, lower leverage
  • +130.1% vs NBTB's +2.6%
Best for: long-term compounding and sleep-well-at-night
NBTB
NBT Bancorp Inc.
The Banking Pick

NBTB ranks third and is worth considering specifically for income & stability.

  • Dividend streak 12 yrs, beta 0.85, yield 3.2%
  • 3.2% yield, 12-year raise streak, vs CZWI's 1.8%, (2 stocks pay no dividend)
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthACNB logoACNB28.9% NII/revenue growth vs PTGX's -89.4%
ValueACNB logoACNBLower P/E (9.6x vs 10.6x), PEG 0.87 vs 1.50
Quality / MarginsACNB logoACNB21.7% margin vs PTGX's -6.5%
Stability / SafetyPTGX logoPTGXBeta 0.20 vs NBTB's 0.85, lower leverage
DividendsNBTB logoNBTB3.2% yield, 12-year raise streak, vs CZWI's 1.8%, (2 stocks pay no dividend)
Momentum (1Y)PTGX logoPTGX+130.1% vs NBTB's +2.6%
Efficiency (ROA)ACNB logoACNB1.1% ROA vs MPLT's -69.7%, ROIC 5.3% vs -153.7%

MPLT vs ACNB vs CZWI vs PTGX vs NBTB — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MPLTMapLight Therapeutics, Inc.

Segment breakdown not available.

ACNBACNB Corporation
FY 2025
Mortgage Banking
29.0%$5M
Deposit Account
26.7%$5M
Fiduciary and Trust
24.7%$4M
ATM Service Charges and Debit Card Transactions
19.6%$4M
CZWICitizens Community Bancorp, Inc.
FY 2025
Reportable Segment
100.0%$99M
PTGXProtagonist Therapeutics, Inc.
FY 2024
Development Services
100.0%$15M
NBTBNBT Bancorp Inc.
FY 2025
Insurance Revenue
100.0%$18M

MPLT vs ACNB vs CZWI vs PTGX vs NBTB — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLACNBLAGGINGCZWI

Income & Cash Flow (Last 12 Months)

ACNB leads this category, winning 3 of 5 comparable metrics.

NBTB and MPLT operate at a comparable scale, with $867M and $0 in trailing revenue. ACNB is the more profitable business, keeping 21.7% of every revenue dollar as net income compared to PTGX's -6.5%.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…NBTB logoNBTBNBT Bancorp Inc.
RevenueTrailing 12 months$0$170M$90M$18M$867M
EBITDAEarnings before interest/tax-$108M$53M$9M-$141M$241M
Net IncomeAfter-tax profit-$103M$37M$14M-$115M$169M
Free Cash FlowCash after capex-$113M$51M$11M-$116M$225M
Gross MarginGross profit ÷ Revenue+73.7%+54.7%+100.0%+72.1%
Operating MarginEBIT ÷ Revenue+27.3%+7.0%-8.1%+25.3%
Net MarginNet income ÷ Revenue+21.7%+16.0%-6.5%+19.5%
FCF MarginFCF ÷ Revenue+30.9%+11.5%-6.6%+25.2%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%
EPS Growth (YoY)Latest quarter vs prior year+35.1%+63.0%+126.3%+39.5%
ACNB leads this category, winning 3 of 5 comparable metrics.

Valuation Metrics

ACNB leads this category, winning 3 of 7 comparable metrics.

At 13.2x trailing earnings, NBTB trades at a 8% valuation discount to ACNB's 14.5x P/E. Adjusting for growth (PEG ratio), ACNB offers better value at 1.31x vs CZWI's 2.78x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…NBTB logoNBTBNBT Bancorp Inc.
Market CapShares × price$1.3B$539M$198M$6.6B$2.3B
Enterprise ValueMkt cap + debt − cash$1.3B$847M$131M$6.5B$2.4B
Trailing P/EPrice ÷ TTM EPS-15.36x14.45x14.10x-49.84x13.24x
Forward P/EPrice ÷ next-FY EPS est.9.65x11.31x25.74x10.56x
PEG RatioP/E ÷ EPS growth rate1.31x2.78x1.88x
EV / EBITDAEnterprise value multiple15.93x14.74x10.14x
Price / SalesMarket cap ÷ Revenue3.16x2.20x142.81x2.65x
Price / BookPrice ÷ Book value/share10.33x1.27x1.06x10.57x1.18x
Price / FCFMarket cap ÷ FCF10.25x19.09x117.18x10.51x
ACNB leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — ACNB and NBTB each lead in 3 of 9 comparable metrics.

NBTB delivers a 9.5% return on equity — every $100 of shareholder capital generates $10 in annual profit, vs $-2 for MPLT. PTGX carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to ACNB's 0.78x. On the Piotroski fundamental quality scale (0–9), NBTB scores 7/9 vs PTGX's 4/9, reflecting strong financial health.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…NBTB logoNBTBNBT Bancorp Inc.
ROE (TTM)Return on equity-2.1%+9.2%+7.8%-17.8%+9.5%
ROA (TTM)Return on assets-69.7%+1.1%+0.8%-16.5%+1.1%
ROICReturn on invested capital-153.7%+5.3%+2.0%-21.8%+7.9%
ROCEReturn on capital employed-83.9%+2.5%+0.6%-23.9%+2.4%
Piotroski ScoreFundamental quality 0–945647
Debt / EquityFinancial leverage0.06x0.78x0.28x0.02x0.17x
Net DebtTotal debt minus cash-$32M$308M-$67M-$118M$142M
Cash & Equiv.Liquid assets$38M$21M$119M$128M$185M
Total DebtShort + long-term debt$7M$329M$52M$10M$327M
Interest CoverageEBIT ÷ Interest expense1.16x0.16x1.05x
Evenly matched — ACNB and NBTB each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

PTGX leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in PTGX five years ago would be worth $33,981 today (with dividends reinvested), compared to $12,424 for NBTB. Over the past 12 months, PTGX leads with a +130.1% total return vs NBTB's +2.6%. The 3-year compound annual growth rate (CAGR) favors PTGX at 57.9% vs NBTB's 13.1% — a key indicator of consistent wealth creation.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…NBTB logoNBTBNBT Bancorp Inc.
YTD ReturnYear-to-date+59.5%+10.9%+19.3%+17.2%+6.9%
1-Year ReturnPast 12 months+59.5%+21.1%+39.5%+130.1%+2.6%
3-Year ReturnCumulative with dividends+59.5%+89.1%+170.4%+293.5%+44.7%
5-Year ReturnCumulative with dividends+59.5%+103.0%+66.2%+239.8%+24.2%
10-Year ReturnCumulative with dividends+59.5%+177.0%+150.2%+773.3%+97.4%
CAGR (3Y)Annualised 3-year return+16.8%+23.7%+39.3%+57.9%+13.1%
PTGX leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ACNB and PTGX each lead in 1 of 2 comparable metrics.

PTGX is the less volatile stock with a 0.20 beta — it tends to amplify market swings less than NBTB's 0.85 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ACNB currently trades 96.5% from its 52-week high vs MPLT's 86.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…NBTB logoNBTBNBT Bancorp Inc.
Beta (5Y)Sensitivity to S&P 5000.69x0.50x0.20x0.85x
52-Week HighHighest price in past year$33.28$53.93$22.62$107.84$46.92
52-Week LowLowest price in past year$16.34$40.15$12.83$43.47$39.20
% of 52W HighCurrent price vs 52-week peak+86.3%+96.5%+91.0%+94.8%+94.0%
RSI (14)Momentum oscillator 0–10054.257.556.657.149.6
Avg Volume (50D)Average daily shares traded265K62K38K722K247K
Evenly matched — ACNB and PTGX each lead in 1 of 2 comparable metrics.

Analyst Outlook

NBTB leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: ACNB as "Buy", CZWI as "Buy", PTGX as "Buy", NBTB as "Hold". Consensus price targets imply 17.6% upside for MPLT (target: $34) vs 4.3% for NBTB (target: $46). For income investors, NBTB offers the higher dividend yield at 3.24% vs CZWI's 1.80%.

MetricMPLT logoMPLTMapLight Therapeu…ACNB logoACNBACNB CorporationCZWI logoCZWICitizens Communit…PTGX logoPTGXProtagonist Thera…NBTB logoNBTBNBT Bancorp Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHold
Price TargetConsensus 12-month target$33.80$58.00$115.40$46.00
# AnalystsCovering analysts222610
Dividend YieldAnnual dividend ÷ price+2.7%+1.8%+3.2%
Dividend StreakConsecutive years of raises8712
Dividend / ShareAnnual DPS$1.40$0.37$1.43
Buyback YieldShare repurchases ÷ mkt cap0.0%+2.1%+3.2%0.0%+0.4%
NBTB leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ACNB leads in 2 of 6 categories (Income & Cash Flow, Valuation Metrics). PTGX leads in 1 (Total Returns). 2 tied.

Best OverallACNB Corporation (ACNB)Leads 2 of 6 categories
Loading custom metrics...

MPLT vs ACNB vs CZWI vs PTGX vs NBTB: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MPLT or ACNB or CZWI or PTGX or NBTB a better buy right now?

For growth investors, ACNB Corporation (ACNB) is the stronger pick with 28.

9% revenue growth year-over-year, versus -89. 4% for Protagonist Therapeutics, Inc. (PTGX). NBT Bancorp Inc. (NBTB) offers the better valuation at 13. 2x trailing P/E (10. 6x forward), making it the more compelling value choice. Analysts rate ACNB Corporation (ACNB) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MPLT or ACNB or CZWI or PTGX or NBTB?

On trailing P/E, NBT Bancorp Inc.

(NBTB) is the cheapest at 13. 2x versus ACNB Corporation at 14. 5x. On forward P/E, ACNB Corporation is actually cheaper at 9. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: ACNB Corporation wins at 0. 87x versus Citizens Community Bancorp, Inc. 's 2. 23x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — MPLT or ACNB or CZWI or PTGX or NBTB?

Over the past 5 years, Protagonist Therapeutics, Inc.

(PTGX) delivered a total return of +239. 8%, compared to +24. 2% for NBT Bancorp Inc. (NBTB). Over 10 years, the gap is even starker: PTGX returned +773. 3% versus MPLT's +59. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MPLT or ACNB or CZWI or PTGX or NBTB?

By beta (market sensitivity over 5 years), Protagonist Therapeutics, Inc.

(PTGX) is the lower-risk stock at 0. 20β versus NBT Bancorp Inc. 's 0. 85β — meaning NBTB is approximately 327% more volatile than PTGX relative to the S&P 500. On balance sheet safety, Protagonist Therapeutics, Inc. (PTGX) carries a lower debt/equity ratio of 2% versus 78% for ACNB Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — MPLT or ACNB or CZWI or PTGX or NBTB?

By revenue growth (latest reported year), ACNB Corporation (ACNB) is pulling ahead at 28.

9% versus -89. 4% for Protagonist Therapeutics, Inc. (PTGX). On earnings-per-share growth, the picture is similar: NBT Bancorp Inc. grew EPS 12. 5% year-over-year, compared to -148. 5% for Protagonist Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MPLT or ACNB or CZWI or PTGX or NBTB?

ACNB Corporation (ACNB) is the more profitable company, earning 21.

7% net margin versus -282. 8% for Protagonist Therapeutics, Inc. — meaning it keeps 21. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ACNB leads at 27. 3% versus -343. 6% for PTGX. At the gross margin level — before operating expenses — PTGX leads at 97. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MPLT or ACNB or CZWI or PTGX or NBTB more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, ACNB Corporation (ACNB) is the more undervalued stock at a PEG of 0. 87x versus Citizens Community Bancorp, Inc. 's 2. 23x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, ACNB Corporation (ACNB) trades at 9. 6x forward P/E versus 25. 7x for Protagonist Therapeutics, Inc. — 16. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MPLT: 17. 6% to $33. 80.

08

Which pays a better dividend — MPLT or ACNB or CZWI or PTGX or NBTB?

In this comparison, NBTB (3.

2% yield), ACNB (2. 7% yield), CZWI (1. 8% yield) pay a dividend. MPLT, PTGX do not pay a meaningful dividend and should not be held primarily for income.

09

Is MPLT or ACNB or CZWI or PTGX or NBTB better for a retirement portfolio?

For long-horizon retirement investors, Protagonist Therapeutics, Inc.

(PTGX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 20), +773. 3% 10Y return). Both have compounded well over 10 years (PTGX: +773. 3%, MPLT: +59. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MPLT and ACNB and CZWI and PTGX and NBTB?

These companies operate in different sectors (MPLT (Healthcare) and ACNB (Financial Services) and CZWI (Financial Services) and PTGX (Healthcare) and NBTB (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: MPLT is a small-cap quality compounder stock; ACNB is a small-cap high-growth stock; CZWI is a small-cap deep-value stock; PTGX is a small-cap quality compounder stock; NBTB is a small-cap deep-value stock. ACNB, CZWI, NBTB pay a dividend while MPLT, PTGX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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MPLT

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  • Market Cap > $100B
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  • Market Cap > $100B
  • Revenue Growth > 14%
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  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 11%
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