Compare Stocks

4 / 10
Try these comparisons:

Stock Comparison

MYGN vs EXAS vs NTRA vs GH

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MYGN
Myriad Genetics, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$382M
5Y Perf.-71.9%
EXAS
Exact Sciences Corporation

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$20.02B
5Y Perf.+20.4%
NTRA
Natera, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$31.16B
5Y Perf.+401.3%
GH
Guardant Health, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$12.10B
5Y Perf.+2.1%

MYGN vs EXAS vs NTRA vs GH — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MYGN logoMYGN
EXAS logoEXAS
NTRA logoNTRA
GH logoGH
IndustryMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$382M$20.02B$31.16B$12.10B
Revenue (TTM)$829M$3.25B$2.31B$1.08B
Net Income (TTM)$-400M$-208M$-208M$-433M
Gross Margin70.0%69.7%64.8%64.9%
Operating Margin-46.3%-6.4%-13.4%-41.4%
Forward P/E117.5x582.8x
Total Debt$210M$2.52B$214M$1.68B
Cash & Equiv.$150M$956M$1.08B$378M

MYGN vs EXAS vs NTRA vs GHLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MYGN
EXAS
NTRA
GH
StockMay 20May 26Return
Myriad Genetics, In… (MYGN)10028.1-71.9%
Exact Sciences Corp… (EXAS)100120.4+20.4%
Natera, Inc. (NTRA)100501.3+401.3%
Guardant Health, In… (GH)100102.1+2.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: MYGN vs EXAS vs NTRA vs GH

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: EXAS leads in 3 of 7 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Myriad Genetics, Inc. is the stronger pick specifically for valuation and capital efficiency. NTRA and GH also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
MYGN
Myriad Genetics, Inc.
The Value Play

MYGN is the #2 pick in this set and the best alternative if value is your priority.

  • Better valuation composite
Best for: value
EXAS
Exact Sciences Corporation
The Income Pick

EXAS carries the broadest edge in this set and is the clearest fit for income & stability.

  • beta 0.12
  • -6.4% margin vs MYGN's -48.2%
  • Beta 0.12 vs MYGN's 1.91
  • -3.5% ROA vs MYGN's -57.4%, ROIC -3.6% vs -8.7%
Best for: income & stability
NTRA
Natera, Inc.
The Growth Play

NTRA is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 35.9%, EPS growth 0.7%, 3Y rev CAGR 41.1%
  • 20.9% 10Y total return vs EXAS's 16.7%
  • Lower volatility, beta 1.26, Low D/E 12.5%, current ratio 3.39x
  • 35.9% revenue growth vs MYGN's -1.6%
Best for: growth exposure and long-term compounding
GH
Guardant Health, Inc.
The Defensive Pick

GH is the clearest fit if your priority is defensive.

  • Beta 0.86, current ratio 4.84x
  • +132.2% vs MYGN's -4.2%
Best for: defensive
See the full category breakdown
CategoryWinnerWhy
GrowthNTRA logoNTRA35.9% revenue growth vs MYGN's -1.6%
ValueMYGN logoMYGNBetter valuation composite
Quality / MarginsEXAS logoEXAS-6.4% margin vs MYGN's -48.2%
Stability / SafetyEXAS logoEXASBeta 0.12 vs MYGN's 1.91
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)GH logoGH+132.2% vs MYGN's -4.2%
Efficiency (ROA)EXAS logoEXAS-3.5% ROA vs MYGN's -57.4%, ROIC -3.6% vs -8.7%

MYGN vs EXAS vs NTRA vs GH — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MYGNMyriad Genetics, Inc.
FY 2023
Testing Revenue
100.0%$753M
EXASExact Sciences Corporation
FY 2025
Screening
77.9%$2.5B
Precision Oncology
22.1%$717M
NTRANatera, Inc.
FY 2025
Product
99.6%$2.3B
Licensing and other
0.4%$10M
GHGuardant Health, Inc.
FY 2025
Oncology
69.6%$684M
Biopharma & Data
21.4%$210M
Screening
8.1%$80M
Licensing & Other
0.9%$9M

MYGN vs EXAS vs NTRA vs GH — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLEXASLAGGINGGH

Income & Cash Flow (Last 12 Months)

EXAS leads this category, winning 3 of 6 comparable metrics.

EXAS is the larger business by revenue, generating $3.2B annually — 3.9x MYGN's $829M. EXAS is the more profitable business, keeping -6.4% of every revenue dollar as net income compared to MYGN's -48.2%. On growth, GH holds the edge at +48.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMYGN logoMYGNMyriad Genetics, …EXAS logoEXASExact Sciences Co…NTRA logoNTRANatera, Inc.GH logoGHGuardant Health, …
RevenueTrailing 12 months$829M$3.2B$2.3B$1.1B
EBITDAEarnings before interest/tax-$344M-$41M-$310M-$418M
Net IncomeAfter-tax profit-$400M-$208M-$208M-$433M
Free Cash FlowCash after capex-$21M$357M$97M-$225M
Gross MarginGross profit ÷ Revenue+70.0%+69.7%+64.8%+64.9%
Operating MarginEBIT ÷ Revenue-46.3%-6.4%-13.4%-41.4%
Net MarginNet income ÷ Revenue-48.2%-6.4%-9.0%-40.1%
FCF MarginFCF ÷ Revenue-2.5%+11.0%+4.2%-20.8%
Rev. Growth (YoY)Latest quarter vs prior year+2.3%+23.1%+39.8%+48.3%
EPS Growth (YoY)Latest quarter vs prior year+90.4%+185.4%-10.4%
EXAS leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

MYGN leads this category, winning 3 of 5 comparable metrics.
MetricMYGN logoMYGNMyriad Genetics, …EXAS logoEXASExact Sciences Co…NTRA logoNTRANatera, Inc.GH logoGHGuardant Health, …
Market CapShares × price$382M$20.0B$31.2B$12.1B
Enterprise ValueMkt cap + debt − cash$443M$21.6B$30.3B$13.4B
Trailing P/EPrice ÷ TTM EPS-1.03x-95.37x-144.62x-27.79x
Forward P/EPrice ÷ next-FY EPS est.117.53x582.83x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue0.46x6.16x13.51x12.32x
Price / BookPrice ÷ Book value/share1.04x8.24x17.55x
Price / FCFMarket cap ÷ FCF56.10x285.53x
MYGN leads this category, winning 3 of 5 comparable metrics.

Profitability & Efficiency

EXAS leads this category, winning 6 of 9 comparable metrics.

EXAS delivers a -8.7% return on equity — every $100 of shareholder capital generates $-9 in annual profit, vs $-109 for MYGN. NTRA carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to EXAS's 1.05x. On the Piotroski fundamental quality scale (0–9), EXAS scores 7/9 vs GH's 5/9, reflecting strong financial health.

MetricMYGN logoMYGNMyriad Genetics, …EXAS logoEXASExact Sciences Co…NTRA logoNTRANatera, Inc.GH logoGHGuardant Health, …
ROE (TTM)Return on equity-109.1%-8.7%-15.3%
ROA (TTM)Return on assets-57.4%-3.5%-10.6%-26.5%
ROICReturn on invested capital-8.7%-3.6%-36.1%-34.9%
ROCEReturn on capital employed-9.4%-4.0%-18.3%-29.4%
Piotroski ScoreFundamental quality 0–95755
Debt / EquityFinancial leverage0.57x1.05x0.13x
Net DebtTotal debt minus cash$60M$1.6B-$862M$1.3B
Cash & Equiv.Liquid assets$150M$956M$1.1B$378M
Total DebtShort + long-term debt$210M$2.5B$214M$1.7B
Interest CoverageEBIT ÷ Interest expense-63.57x-5.47x-25.21x-181.67x
EXAS leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NTRA leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in NTRA five years ago would be worth $21,587 today (with dividends reinvested), compared to $1,448 for MYGN. Over the past 12 months, GH leads with a +132.2% total return vs MYGN's -4.2%. The 3-year compound annual growth rate (CAGR) favors NTRA at 60.6% vs MYGN's -39.3% — a key indicator of consistent wealth creation.

MetricMYGN logoMYGNMyriad Genetics, …EXAS logoEXASExact Sciences Co…NTRA logoNTRANatera, Inc.GH logoGHGuardant Health, …
YTD ReturnYear-to-date-33.4%+3.1%-3.9%-9.3%
1-Year ReturnPast 12 months-4.2%+96.9%+37.3%+132.2%
3-Year ReturnCumulative with dividends-77.7%+53.0%+314.0%+292.1%
5-Year ReturnCumulative with dividends-85.5%+0.4%+115.9%-31.9%
10-Year ReturnCumulative with dividends-88.5%+1669.1%+2089.4%+186.5%
CAGR (3Y)Annualised 3-year return-39.3%+15.2%+60.6%+57.7%
NTRA leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

EXAS leads this category, winning 2 of 2 comparable metrics.

EXAS is the less volatile stock with a 0.12 beta — it tends to amplify market swings less than MYGN's 1.91 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. EXAS currently trades 99.9% from its 52-week high vs MYGN's 47.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMYGN logoMYGNMyriad Genetics, …EXAS logoEXASExact Sciences Co…NTRA logoNTRANatera, Inc.GH logoGHGuardant Health, …
Beta (5Y)Sensitivity to S&P 5001.91x0.12x1.26x0.86x
52-Week HighHighest price in past year$8.59$104.98$256.36$120.74
52-Week LowLowest price in past year$3.75$38.81$131.81$36.36
% of 52W HighCurrent price vs 52-week peak+47.6%+99.9%+85.7%+76.4%
RSI (14)Momentum oscillator 0–10035.576.457.155.9
Avg Volume (50D)Average daily shares traded1.8M4.2M1.3M1.9M
EXAS leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: MYGN as "Hold", EXAS as "Buy", NTRA as "Buy", GH as "Buy". Consensus price targets imply 46.7% upside for MYGN (target: $6) vs -1.6% for EXAS (target: $103).

MetricMYGN logoMYGNMyriad Genetics, …EXAS logoEXASExact Sciences Co…NTRA logoNTRANatera, Inc.GH logoGHGuardant Health, …
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuy
Price TargetConsensus 12-month target$6.00$103.18$262.50$133.14
# AnalystsCovering analysts36412730
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.1%0.0%+0.1%
Insufficient data to determine a leader in this category.
Key Takeaway

EXAS leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). MYGN leads in 1 (Valuation Metrics).

Best OverallExact Sciences Corporation (EXAS)Leads 3 of 6 categories
Loading custom metrics...

MYGN vs EXAS vs NTRA vs GH: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is MYGN or EXAS or NTRA or GH a better buy right now?

For growth investors, Natera, Inc.

(NTRA) is the stronger pick with 35. 9% revenue growth year-over-year, versus -1. 6% for Myriad Genetics, Inc. (MYGN). Analysts rate Exact Sciences Corporation (EXAS) a "Buy" — based on 41 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — MYGN or EXAS or NTRA or GH?

Over the past 5 years, Natera, Inc.

(NTRA) delivered a total return of +115. 9%, compared to -85. 5% for Myriad Genetics, Inc. (MYGN). Over 10 years, the gap is even starker: NTRA returned +20. 9% versus MYGN's -88. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — MYGN or EXAS or NTRA or GH?

By beta (market sensitivity over 5 years), Exact Sciences Corporation (EXAS) is the lower-risk stock at 0.

12β versus Myriad Genetics, Inc. 's 1. 91β — meaning MYGN is approximately 1483% more volatile than EXAS relative to the S&P 500. On balance sheet safety, Natera, Inc. (NTRA) carries a lower debt/equity ratio of 13% versus 105% for Exact Sciences Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — MYGN or EXAS or NTRA or GH?

By revenue growth (latest reported year), Natera, Inc.

(NTRA) is pulling ahead at 35. 9% versus -1. 6% for Myriad Genetics, Inc. (MYGN). On earnings-per-share growth, the picture is similar: Exact Sciences Corporation grew EPS 80. 3% year-over-year, compared to -180. 9% for Myriad Genetics, Inc.. Over a 3-year CAGR, NTRA leads at 41. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — MYGN or EXAS or NTRA or GH?

Exact Sciences Corporation (EXAS) is the more profitable company, earning -6.

4% net margin versus -44. 4% for Myriad Genetics, Inc. — meaning it keeps -6. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EXAS leads at -6. 4% versus -44. 4% for GH. At the gross margin level — before operating expenses — MYGN leads at 69. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is MYGN or EXAS or NTRA or GH more undervalued right now?

On forward earnings alone, Myriad Genetics, Inc.

(MYGN) trades at 117. 5x forward P/E versus 582. 8x for Exact Sciences Corporation — 465. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MYGN: 46. 7% to $6. 00.

07

Which pays a better dividend — MYGN or EXAS or NTRA or GH?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is MYGN or EXAS or NTRA or GH better for a retirement portfolio?

For long-horizon retirement investors, Exact Sciences Corporation (EXAS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

12), +1669% 10Y return). Myriad Genetics, Inc. (MYGN) carries a higher beta of 1. 91 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (EXAS: +1669%, MYGN: -88. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between MYGN and EXAS and NTRA and GH?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: MYGN is a small-cap quality compounder stock; EXAS is a mid-cap high-growth stock; NTRA is a mid-cap high-growth stock; GH is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.

Stocks Like

MYGN

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 41%
Run This Screen
Stocks Like

EXAS

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 11%
  • Gross Margin > 41%
Run This Screen
Stocks Like

NTRA

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 19%
  • Gross Margin > 38%
Run This Screen
Stocks Like

GH

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 24%
  • Gross Margin > 38%
Run This Screen
Custom Screen

Beat Both

Find stocks that outperform MYGN and EXAS and NTRA and GH on the metrics below

Revenue Growth>
%
(MYGN: 2.3% · EXAS: 23.1%)

You Might Also Compare

Based on how these companies actually compete and overlap — not just which sector they're filed under.