Drug Manufacturers - General
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NVO vs DBVT vs SNY vs AZN vs MRK
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - General
Drug Manufacturers - General
Drug Manufacturers - General
NVO vs DBVT vs SNY vs AZN vs MRK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Drug Manufacturers - General | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $203.48B | $1712.35T | $104.28B | $282.96B | $277.34B |
| Revenue (TTM) | $327.80B | $0.00 | $46.72B | $60.44B | $64.93B |
| Net Income (TTM) | $121.96B | $-168M | $7.81B | $10.39B | $18.25B |
| Gross Margin | 81.8% | — | 72.3% | 81.7% | 74.2% |
| Operating Margin | 45.3% | — | 13.6% | 23.7% | 41.1% |
| Forward P/E | 2.1x | — | 10.3x | 17.7x | 21.9x |
| Total Debt | $130.96B | $22M | $21.79B | $29.70B | $50.53B |
| Cash & Equiv. | $26.46B | $194M | $7.66B | $5.71B | $14.56B |
NVO vs DBVT vs SNY vs AZN vs MRK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Novo Nordisk A/S (NVO) | 100 | 138.9 | +38.9% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Sanofi (SNY) | 100 | 87.9 | -12.1% |
| AstraZeneca PLC (AZN) | 100 | 170.2 | +70.2% |
| Merck & Co., Inc. (MRK) | 100 | 145.9 | +45.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: NVO vs DBVT vs SNY vs AZN vs MRK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
NVO carries the broadest edge in this set and is the clearest fit for valuation efficiency.
- PEG 0.10 vs MRK's 1.03
- Lower P/E (2.1x vs 21.9x), PEG 0.10 vs 1.03
- 37.2% margin vs DBVT's 0.3%
- 23.3% ROA vs DBVT's -89.0%
DBVT is the #2 pick in this set and the best alternative if momentum is your priority.
- +110.4% vs NVO's -29.5%
SNY ranks third and is worth considering specifically for sleep-well-at-night and defensive.
- Lower volatility, beta 0.51, Low D/E 30.4%, current ratio 1.09x
- Beta 0.51, yield 5.1%, current ratio 1.09x
- 5.1% yield, vs MRK's 2.9%, (1 stock pays no dividend)
AZN is the clearest fit if your priority is growth exposure and long-term compounding.
- Rev growth 8.6%, EPS growth 190.7%, 3Y rev CAGR 9.8%
- 268.6% 10Y total return vs MRK's 166.5%
- 8.6% revenue growth vs DBVT's -100.0%
MRK is the clearest fit if your priority is income & stability.
- Dividend streak 14 yrs, beta 0.48, yield 2.9%
- Beta 0.48 vs NVO's 1.56
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (2.1x vs 21.9x), PEG 0.10 vs 1.03 | |
| Quality / Margins | 37.2% margin vs DBVT's 0.3% | |
| Stability / Safety | Beta 0.48 vs NVO's 1.56 | |
| Dividends | 5.1% yield, vs MRK's 2.9%, (1 stock pays no dividend) | |
| Momentum (1Y) | +110.4% vs NVO's -29.5% | |
| Efficiency (ROA) | 23.3% ROA vs DBVT's -89.0% |
NVO vs DBVT vs SNY vs AZN vs MRK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
NVO vs DBVT vs SNY vs AZN vs MRK — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NVO leads in 3 of 6 categories
AZN leads 1 • MRK leads 1 • DBVT leads 0 • SNY leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NVO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVO and DBVT operate at a comparable scale, with $327.8B and $0 in trailing revenue. NVO is the more profitable business, keeping 37.2% of every revenue dollar as net income compared to SNY's 16.7%. On growth, SNY holds the edge at +59.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $327.8B | $0 | $46.7B | $60.4B | $64.9B |
| EBITDAEarnings before interest/tax | $170.2B | -$112M | $9.6B | $20.1B | $32.4B |
| Net IncomeAfter-tax profit | $122.0B | -$168M | $7.8B | $10.4B | $18.3B |
| Free Cash FlowCash after capex | $31.0B | -$151M | $8.3B | $9.1B | $12.4B |
| Gross MarginGross profit ÷ Revenue | +81.8% | — | +72.3% | +81.7% | +74.2% |
| Operating MarginEBIT ÷ Revenue | +45.3% | — | +13.6% | +23.7% | +41.1% |
| Net MarginNet income ÷ Revenue | +37.2% | — | +16.7% | +17.2% | +28.1% |
| FCF MarginFCF ÷ Revenue | +9.5% | — | +17.7% | +15.1% | +19.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +24.0% | — | +59.9% | +12.5% | +4.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +67.1% | +91.5% | -5.2% | +5.3% | -19.6% |
Valuation Metrics
NVO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 12.6x trailing earnings, NVO trades at a 55% valuation discount to AZN's 27.9x P/E. Adjusting for growth (PEG ratio), NVO offers better value at 0.61x vs AZN's 1.28x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $203.5B | $1712.35T | $104.3B | $283.0B | $277.3B |
| Enterprise ValueMkt cap + debt − cash | $219.9B | $1712.35T | $120.9B | $306.9B | $313.3B |
| Trailing P/EPrice ÷ TTM EPS | 12.64x | -0.76x | 18.10x | 27.91x | 15.42x |
| Forward P/EPrice ÷ next-FY EPS est. | 2.15x | — | 10.26x | 17.74x | 21.93x |
| PEG RatioP/E ÷ EPS growth rate | 0.61x | — | — | 1.28x | 0.73x |
| EV / EBITDAEnterprise value multiple | 9.34x | — | 10.77x | 15.76x | 10.68x |
| Price / SalesMarket cap ÷ Revenue | 4.19x | — | 1.90x | 4.82x | 4.27x |
| Price / BookPrice ÷ Book value/share | 6.67x | 0.66x | 1.25x | 5.85x | 5.35x |
| Price / FCFMarket cap ÷ FCF | 44.63x | — | 9.98x | 24.05x | 22.44x |
Profitability & Efficiency
NVO leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
NVO delivers a 66.4% return on equity — every $100 of shareholder capital generates $66 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), AZN scores 8/9 vs MRK's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +66.4% | -130.2% | +10.8% | +22.2% | +36.1% |
| ROA (TTM)Return on assets | +23.3% | -89.0% | +6.1% | +9.1% | +14.6% |
| ROICReturn on invested capital | +36.2% | — | +5.5% | +14.9% | +22.0% |
| ROCEReturn on capital employed | +44.4% | -145.7% | +6.3% | +17.2% | +23.8% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 7 | 8 | 4 |
| Debt / EquityFinancial leverage | 0.67x | 0.13x | 0.30x | 0.61x | 0.96x |
| Net DebtTotal debt minus cash | $104.5B | -$172M | $14.1B | $24.0B | $36.0B |
| Cash & Equiv.Liquid assets | $26.5B | $194M | $7.7B | $5.7B | $14.6B |
| Total DebtShort + long-term debt | $131.0B | $22M | $21.8B | $29.7B | $50.5B |
| Interest CoverageEBIT ÷ Interest expense | 18.90x | -189.82x | 17.51x | 8.43x | 19.68x |
Total Returns (Dividends Reinvested)
AZN leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in AZN five years ago would be worth $18,221 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs NVO's -29.5%. The 3-year compound annual growth rate (CAGR) favors AZN at 9.3% vs NVO's -16.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -10.2% | +4.9% | -6.8% | +1.1% | +6.3% |
| 1-Year ReturnPast 12 months | -29.5% | +110.4% | -9.8% | +33.9% | +46.1% |
| 3-Year ReturnCumulative with dividends | -40.7% | +19.7% | -7.0% | +30.4% | +2.9% |
| 5-Year ReturnCumulative with dividends | +36.4% | -69.1% | +2.5% | +82.2% | +70.2% |
| 10-Year ReturnCumulative with dividends | +99.6% | -87.0% | +57.1% | +268.6% | +166.5% |
| CAGR (3Y)Annualised 3-year return | -16.0% | +6.2% | -2.4% | +9.3% | +0.9% |
Risk & Volatility
MRK leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
MRK is the less volatile stock with a 0.48 beta — it tends to amplify market swings less than NVO's 1.56 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs NVO's 56.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.56x | 1.26x | 0.51x | 0.67x | 0.48x |
| 52-Week HighHighest price in past year | $81.44 | $26.18 | $53.36 | $212.71 | $125.14 |
| 52-Week LowLowest price in past year | $35.12 | $7.53 | $43.09 | $91.44 | $73.31 |
| % of 52W HighCurrent price vs 52-week peak | +56.2% | +76.3% | +80.9% | +85.8% | +89.7% |
| RSI (14)Momentum oscillator 0–100 | 73.4 | 48.1 | 34.1 | 39.1 | 46.7 |
| Avg Volume (50D)Average daily shares traded | 18.4M | 252K | 3.2M | 1.9M | 7.3M |
Analyst Outlook
Evenly matched — SNY and MRK each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: NVO as "Buy", DBVT as "Buy", SNY as "Buy", AZN as "Buy", MRK as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 2.6% for NVO (target: $47). For income investors, SNY offers the higher dividend yield at 5.11% vs AZN's 1.78%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $47.00 | $46.33 | $50.00 | $211.00 | $129.31 |
| # AnalystsCovering analysts | 39 | 15 | 27 | 41 | 37 |
| Dividend YieldAnnual dividend ÷ price | +4.0% | — | +5.1% | +1.8% | +2.9% |
| Dividend StreakConsecutive years of raises | 8 | 0 | 0 | 4 | 14 |
| Dividend / ShareAnnual DPS | $11.64 | — | $1.88 | $3.25 | $3.26 |
| Buyback YieldShare repurchases ÷ mkt cap | +0.1% | 0.0% | +5.4% | +0.3% | +1.8% |
NVO leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). AZN leads in 1 (Total Returns). 1 tied.
NVO vs DBVT vs SNY vs AZN vs MRK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is NVO or DBVT or SNY or AZN or MRK a better buy right now?
For growth investors, AstraZeneca PLC (AZN) is the stronger pick with 8.
6% revenue growth year-over-year, versus 1. 2% for Merck & Co. , Inc. (MRK). Novo Nordisk A/S (NVO) offers the better valuation at 12. 6x trailing P/E (2. 1x forward), making it the more compelling value choice. Analysts rate Novo Nordisk A/S (NVO) a "Buy" — based on 39 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — NVO or DBVT or SNY or AZN or MRK?
On trailing P/E, Novo Nordisk A/S (NVO) is the cheapest at 12.
6x versus AstraZeneca PLC at 27. 9x. On forward P/E, Novo Nordisk A/S is actually cheaper at 2. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Novo Nordisk A/S wins at 0. 10x versus Merck & Co. , Inc. 's 1. 03x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — NVO or DBVT or SNY or AZN or MRK?
Over the past 5 years, AstraZeneca PLC (AZN) delivered a total return of +82.
2%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: AZN returned +268. 6% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — NVO or DBVT or SNY or AZN or MRK?
By beta (market sensitivity over 5 years), Merck & Co.
, Inc. (MRK) is the lower-risk stock at 0. 48β versus Novo Nordisk A/S's 1. 56β — meaning NVO is approximately 228% more volatile than MRK relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — NVO or DBVT or SNY or AZN or MRK?
By revenue growth (latest reported year), AstraZeneca PLC (AZN) is pulling ahead at 8.
6% versus 1. 2% for Merck & Co. , Inc. (MRK). On earnings-per-share growth, the picture is similar: AstraZeneca PLC grew EPS 190. 7% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, NVO leads at 20. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — NVO or DBVT or SNY or AZN or MRK?
Novo Nordisk A/S (NVO) is the more profitable company, earning 33.
1% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 33. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVO leads at 41. 3% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — AZN leads at 81. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is NVO or DBVT or SNY or AZN or MRK more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Novo Nordisk A/S (NVO) is the more undervalued stock at a PEG of 0. 10x versus Merck & Co. , Inc. 's 1. 03x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Novo Nordisk A/S (NVO) trades at 2. 1x forward P/E versus 21. 9x for Merck & Co. , Inc. — 19. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — NVO or DBVT or SNY or AZN or MRK?
In this comparison, SNY (5.
1% yield), NVO (4. 0% yield), MRK (2. 9% yield), AZN (1. 8% yield) pay a dividend. DBVT does not pay a meaningful dividend and should not be held primarily for income.
09Is NVO or DBVT or SNY or AZN or MRK better for a retirement portfolio?
For long-horizon retirement investors, Merck & Co.
, Inc. (MRK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 48), 2. 9% yield, +166. 5% 10Y return). Both have compounded well over 10 years (MRK: +166. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between NVO and DBVT and SNY and AZN and MRK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: NVO is a large-cap deep-value stock; DBVT is a mega-cap quality compounder stock; SNY is a mid-cap income-oriented stock; AZN is a large-cap quality compounder stock; MRK is a large-cap deep-value stock. NVO, SNY, AZN, MRK pay a dividend while DBVT does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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