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NVO vs DBVT vs SNY vs AZN vs MRK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NVO
Novo Nordisk A/S

Drug Manufacturers - General

HealthcareNYSE • DK
Market Cap$203.48B
5Y Perf.+38.9%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-58.8%
SNY
Sanofi

Drug Manufacturers - General

HealthcareNASDAQ • FR
Market Cap$104.28B
5Y Perf.-12.1%
AZN
AstraZeneca PLC

Drug Manufacturers - General

HealthcareNASDAQ • GB
Market Cap$282.96B
5Y Perf.+70.2%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+45.9%

NVO vs DBVT vs SNY vs AZN vs MRK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NVO logoNVO
DBVT logoDBVT
SNY logoSNY
AZN logoAZN
MRK logoMRK
IndustryDrug Manufacturers - GeneralBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$203.48B$1712.35T$104.28B$282.96B$277.34B
Revenue (TTM)$327.80B$0.00$46.72B$60.44B$64.93B
Net Income (TTM)$121.96B$-168M$7.81B$10.39B$18.25B
Gross Margin81.8%72.3%81.7%74.2%
Operating Margin45.3%13.6%23.7%41.1%
Forward P/E2.1x10.3x17.7x21.9x
Total Debt$130.96B$22M$21.79B$29.70B$50.53B
Cash & Equiv.$26.46B$194M$7.66B$5.71B$14.56B

NVO vs DBVT vs SNY vs AZN vs MRKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NVO
DBVT
SNY
AZN
MRK
StockMay 20May 26Return
Novo Nordisk A/S (NVO)100138.9+38.9%
DBV Technologies S.… (DBVT)10041.2-58.8%
Sanofi (SNY)10087.9-12.1%
AstraZeneca PLC (AZN)100170.2+70.2%
Merck & Co., Inc. (MRK)100145.9+45.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: NVO vs DBVT vs SNY vs AZN vs MRK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NVO leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. DBV Technologies S.A. is the stronger pick specifically for recent price momentum and sentiment. SNY, AZN, and MRK also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
NVO
Novo Nordisk A/S
The Value Pick

NVO carries the broadest edge in this set and is the clearest fit for valuation efficiency.

  • PEG 0.10 vs MRK's 1.03
  • Lower P/E (2.1x vs 21.9x), PEG 0.10 vs 1.03
  • 37.2% margin vs DBVT's 0.3%
  • 23.3% ROA vs DBVT's -89.0%
Best for: valuation efficiency
DBVT
DBV Technologies S.A.
The Momentum Pick

DBVT is the #2 pick in this set and the best alternative if momentum is your priority.

  • +110.4% vs NVO's -29.5%
Best for: momentum
SNY
Sanofi
The Defensive Pick

SNY ranks third and is worth considering specifically for sleep-well-at-night and defensive.

  • Lower volatility, beta 0.51, Low D/E 30.4%, current ratio 1.09x
  • Beta 0.51, yield 5.1%, current ratio 1.09x
  • 5.1% yield, vs MRK's 2.9%, (1 stock pays no dividend)
Best for: sleep-well-at-night and defensive
AZN
AstraZeneca PLC
The Growth Play

AZN is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 8.6%, EPS growth 190.7%, 3Y rev CAGR 9.8%
  • 268.6% 10Y total return vs MRK's 166.5%
  • 8.6% revenue growth vs DBVT's -100.0%
Best for: growth exposure and long-term compounding
MRK
Merck & Co., Inc.
The Income Pick

MRK is the clearest fit if your priority is income & stability.

  • Dividend streak 14 yrs, beta 0.48, yield 2.9%
  • Beta 0.48 vs NVO's 1.56
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthAZN logoAZN8.6% revenue growth vs DBVT's -100.0%
ValueNVO logoNVOLower P/E (2.1x vs 21.9x), PEG 0.10 vs 1.03
Quality / MarginsNVO logoNVO37.2% margin vs DBVT's 0.3%
Stability / SafetyMRK logoMRKBeta 0.48 vs NVO's 1.56
DividendsSNY logoSNY5.1% yield, vs MRK's 2.9%, (1 stock pays no dividend)
Momentum (1Y)DBVT logoDBVT+110.4% vs NVO's -29.5%
Efficiency (ROA)NVO logoNVO23.3% ROA vs DBVT's -89.0%

NVO vs DBVT vs SNY vs AZN vs MRK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

NVONovo Nordisk A/S

Segment breakdown not available.

DBVTDBV Technologies S.A.

Segment breakdown not available.

SNYSanofi

Segment breakdown not available.

AZNAstraZeneca PLC
FY 2025
Total Oncology
23.9%$23.7B
CVRM
12.9%$12.8B
Rare Disease
9.2%$9.1B
Farxiga
8.5%$8.4B
Tagrisso
7.3%$7.3B
Imfinzi
6.1%$6.1B
Ultomiris
4.8%$4.7B
Other (22)
27.3%$27.1B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M

NVO vs DBVT vs SNY vs AZN vs MRK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLNVOLAGGINGSNY

Income & Cash Flow (Last 12 Months)

NVO leads this category, winning 3 of 6 comparable metrics.

NVO and DBVT operate at a comparable scale, with $327.8B and $0 in trailing revenue. NVO is the more profitable business, keeping 37.2% of every revenue dollar as net income compared to SNY's 16.7%. On growth, SNY holds the edge at +59.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNVO logoNVONovo Nordisk A/SDBVT logoDBVTDBV Technologies …SNY logoSNYSanofiAZN logoAZNAstraZeneca PLCMRK logoMRKMerck & Co., Inc.
RevenueTrailing 12 months$327.8B$0$46.7B$60.4B$64.9B
EBITDAEarnings before interest/tax$170.2B-$112M$9.6B$20.1B$32.4B
Net IncomeAfter-tax profit$122.0B-$168M$7.8B$10.4B$18.3B
Free Cash FlowCash after capex$31.0B-$151M$8.3B$9.1B$12.4B
Gross MarginGross profit ÷ Revenue+81.8%+72.3%+81.7%+74.2%
Operating MarginEBIT ÷ Revenue+45.3%+13.6%+23.7%+41.1%
Net MarginNet income ÷ Revenue+37.2%+16.7%+17.2%+28.1%
FCF MarginFCF ÷ Revenue+9.5%+17.7%+15.1%+19.0%
Rev. Growth (YoY)Latest quarter vs prior year+24.0%+59.9%+12.5%+4.5%
EPS Growth (YoY)Latest quarter vs prior year+67.1%+91.5%-5.2%+5.3%-19.6%
NVO leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

NVO leads this category, winning 3 of 7 comparable metrics.

At 12.6x trailing earnings, NVO trades at a 55% valuation discount to AZN's 27.9x P/E. Adjusting for growth (PEG ratio), NVO offers better value at 0.61x vs AZN's 1.28x — a lower PEG means you pay less per unit of expected earnings growth.

MetricNVO logoNVONovo Nordisk A/SDBVT logoDBVTDBV Technologies …SNY logoSNYSanofiAZN logoAZNAstraZeneca PLCMRK logoMRKMerck & Co., Inc.
Market CapShares × price$203.5B$1712.35T$104.3B$283.0B$277.3B
Enterprise ValueMkt cap + debt − cash$219.9B$1712.35T$120.9B$306.9B$313.3B
Trailing P/EPrice ÷ TTM EPS12.64x-0.76x18.10x27.91x15.42x
Forward P/EPrice ÷ next-FY EPS est.2.15x10.26x17.74x21.93x
PEG RatioP/E ÷ EPS growth rate0.61x1.28x0.73x
EV / EBITDAEnterprise value multiple9.34x10.77x15.76x10.68x
Price / SalesMarket cap ÷ Revenue4.19x1.90x4.82x4.27x
Price / BookPrice ÷ Book value/share6.67x0.66x1.25x5.85x5.35x
Price / FCFMarket cap ÷ FCF44.63x9.98x24.05x22.44x
NVO leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

NVO leads this category, winning 4 of 9 comparable metrics.

NVO delivers a 66.4% return on equity — every $100 of shareholder capital generates $66 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), AZN scores 8/9 vs MRK's 4/9, reflecting strong financial health.

MetricNVO logoNVONovo Nordisk A/SDBVT logoDBVTDBV Technologies …SNY logoSNYSanofiAZN logoAZNAstraZeneca PLCMRK logoMRKMerck & Co., Inc.
ROE (TTM)Return on equity+66.4%-130.2%+10.8%+22.2%+36.1%
ROA (TTM)Return on assets+23.3%-89.0%+6.1%+9.1%+14.6%
ROICReturn on invested capital+36.2%+5.5%+14.9%+22.0%
ROCEReturn on capital employed+44.4%-145.7%+6.3%+17.2%+23.8%
Piotroski ScoreFundamental quality 0–954784
Debt / EquityFinancial leverage0.67x0.13x0.30x0.61x0.96x
Net DebtTotal debt minus cash$104.5B-$172M$14.1B$24.0B$36.0B
Cash & Equiv.Liquid assets$26.5B$194M$7.7B$5.7B$14.6B
Total DebtShort + long-term debt$131.0B$22M$21.8B$29.7B$50.5B
Interest CoverageEBIT ÷ Interest expense18.90x-189.82x17.51x8.43x19.68x
NVO leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

AZN leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in AZN five years ago would be worth $18,221 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs NVO's -29.5%. The 3-year compound annual growth rate (CAGR) favors AZN at 9.3% vs NVO's -16.0% — a key indicator of consistent wealth creation.

MetricNVO logoNVONovo Nordisk A/SDBVT logoDBVTDBV Technologies …SNY logoSNYSanofiAZN logoAZNAstraZeneca PLCMRK logoMRKMerck & Co., Inc.
YTD ReturnYear-to-date-10.2%+4.9%-6.8%+1.1%+6.3%
1-Year ReturnPast 12 months-29.5%+110.4%-9.8%+33.9%+46.1%
3-Year ReturnCumulative with dividends-40.7%+19.7%-7.0%+30.4%+2.9%
5-Year ReturnCumulative with dividends+36.4%-69.1%+2.5%+82.2%+70.2%
10-Year ReturnCumulative with dividends+99.6%-87.0%+57.1%+268.6%+166.5%
CAGR (3Y)Annualised 3-year return-16.0%+6.2%-2.4%+9.3%+0.9%
AZN leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

MRK leads this category, winning 2 of 2 comparable metrics.

MRK is the less volatile stock with a 0.48 beta — it tends to amplify market swings less than NVO's 1.56 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs NVO's 56.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNVO logoNVONovo Nordisk A/SDBVT logoDBVTDBV Technologies …SNY logoSNYSanofiAZN logoAZNAstraZeneca PLCMRK logoMRKMerck & Co., Inc.
Beta (5Y)Sensitivity to S&P 5001.56x1.26x0.51x0.67x0.48x
52-Week HighHighest price in past year$81.44$26.18$53.36$212.71$125.14
52-Week LowLowest price in past year$35.12$7.53$43.09$91.44$73.31
% of 52W HighCurrent price vs 52-week peak+56.2%+76.3%+80.9%+85.8%+89.7%
RSI (14)Momentum oscillator 0–10073.448.134.139.146.7
Avg Volume (50D)Average daily shares traded18.4M252K3.2M1.9M7.3M
MRK leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — SNY and MRK each lead in 1 of 2 comparable metrics.

Analyst consensus: NVO as "Buy", DBVT as "Buy", SNY as "Buy", AZN as "Buy", MRK as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 2.6% for NVO (target: $47). For income investors, SNY offers the higher dividend yield at 5.11% vs AZN's 1.78%.

MetricNVO logoNVONovo Nordisk A/SDBVT logoDBVTDBV Technologies …SNY logoSNYSanofiAZN logoAZNAstraZeneca PLCMRK logoMRKMerck & Co., Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$47.00$46.33$50.00$211.00$129.31
# AnalystsCovering analysts3915274137
Dividend YieldAnnual dividend ÷ price+4.0%+5.1%+1.8%+2.9%
Dividend StreakConsecutive years of raises800414
Dividend / ShareAnnual DPS$11.64$1.88$3.25$3.26
Buyback YieldShare repurchases ÷ mkt cap+0.1%0.0%+5.4%+0.3%+1.8%
Evenly matched — SNY and MRK each lead in 1 of 2 comparable metrics.
Key Takeaway

NVO leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). AZN leads in 1 (Total Returns). 1 tied.

Best OverallNovo Nordisk A/S (NVO)Leads 3 of 6 categories
Loading custom metrics...

NVO vs DBVT vs SNY vs AZN vs MRK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is NVO or DBVT or SNY or AZN or MRK a better buy right now?

For growth investors, AstraZeneca PLC (AZN) is the stronger pick with 8.

6% revenue growth year-over-year, versus 1. 2% for Merck & Co. , Inc. (MRK). Novo Nordisk A/S (NVO) offers the better valuation at 12. 6x trailing P/E (2. 1x forward), making it the more compelling value choice. Analysts rate Novo Nordisk A/S (NVO) a "Buy" — based on 39 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — NVO or DBVT or SNY or AZN or MRK?

On trailing P/E, Novo Nordisk A/S (NVO) is the cheapest at 12.

6x versus AstraZeneca PLC at 27. 9x. On forward P/E, Novo Nordisk A/S is actually cheaper at 2. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Novo Nordisk A/S wins at 0. 10x versus Merck & Co. , Inc. 's 1. 03x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — NVO or DBVT or SNY or AZN or MRK?

Over the past 5 years, AstraZeneca PLC (AZN) delivered a total return of +82.

2%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: AZN returned +268. 6% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — NVO or DBVT or SNY or AZN or MRK?

By beta (market sensitivity over 5 years), Merck & Co.

, Inc. (MRK) is the lower-risk stock at 0. 48β versus Novo Nordisk A/S's 1. 56β — meaning NVO is approximately 228% more volatile than MRK relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — NVO or DBVT or SNY or AZN or MRK?

By revenue growth (latest reported year), AstraZeneca PLC (AZN) is pulling ahead at 8.

6% versus 1. 2% for Merck & Co. , Inc. (MRK). On earnings-per-share growth, the picture is similar: AstraZeneca PLC grew EPS 190. 7% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, NVO leads at 20. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — NVO or DBVT or SNY or AZN or MRK?

Novo Nordisk A/S (NVO) is the more profitable company, earning 33.

1% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 33. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVO leads at 41. 3% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — AZN leads at 81. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is NVO or DBVT or SNY or AZN or MRK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Novo Nordisk A/S (NVO) is the more undervalued stock at a PEG of 0. 10x versus Merck & Co. , Inc. 's 1. 03x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Novo Nordisk A/S (NVO) trades at 2. 1x forward P/E versus 21. 9x for Merck & Co. , Inc. — 19. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.

08

Which pays a better dividend — NVO or DBVT or SNY or AZN or MRK?

In this comparison, SNY (5.

1% yield), NVO (4. 0% yield), MRK (2. 9% yield), AZN (1. 8% yield) pay a dividend. DBVT does not pay a meaningful dividend and should not be held primarily for income.

09

Is NVO or DBVT or SNY or AZN or MRK better for a retirement portfolio?

For long-horizon retirement investors, Merck & Co.

, Inc. (MRK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 48), 2. 9% yield, +166. 5% 10Y return). Both have compounded well over 10 years (MRK: +166. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between NVO and DBVT and SNY and AZN and MRK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: NVO is a large-cap deep-value stock; DBVT is a mega-cap quality compounder stock; SNY is a mid-cap income-oriented stock; AZN is a large-cap quality compounder stock; MRK is a large-cap deep-value stock. NVO, SNY, AZN, MRK pay a dividend while DBVT does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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