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NVS vs DBVT vs AZN vs NVO vs MRK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NVS
Novartis AG

Drug Manufacturers - General

HealthcareNYSE • CH
Market Cap$277.42B
5Y Perf.+75.7%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-58.8%
AZN
AstraZeneca PLC

Drug Manufacturers - General

HealthcareNASDAQ • GB
Market Cap$282.96B
5Y Perf.+70.2%
NVO
Novo Nordisk A/S

Drug Manufacturers - General

HealthcareNYSE • DK
Market Cap$203.48B
5Y Perf.+38.9%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+45.9%

NVS vs DBVT vs AZN vs NVO vs MRK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NVS logoNVS
DBVT logoDBVT
AZN logoAZN
NVO logoNVO
MRK logoMRK
IndustryDrug Manufacturers - GeneralBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$277.42B$1712.35T$282.96B$203.48B$277.34B
Revenue (TTM)$56.05B$0.00$60.44B$327.80B$64.93B
Net Income (TTM)$13.53B$-168M$10.39B$121.96B$18.25B
Gross Margin75.3%81.7%81.8%74.2%
Operating Margin30.5%23.7%45.3%41.1%
Forward P/E16.6x17.7x2.1x21.9x
Total Debt$37.03B$22M$29.70B$130.96B$50.53B
Cash & Equiv.$11.44B$194M$5.71B$26.46B$14.56B

NVS vs DBVT vs AZN vs NVO vs MRKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NVS
DBVT
AZN
NVO
MRK
StockMay 20May 26Return
Novartis AG (NVS)100175.7+75.7%
DBV Technologies S.… (DBVT)10041.2-58.8%
AstraZeneca PLC (AZN)100170.2+70.2%
Novo Nordisk A/S (NVO)100138.9+38.9%
Merck & Co., Inc. (MRK)100145.9+45.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: NVS vs DBVT vs AZN vs NVO vs MRK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NVO leads in 4 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Novartis AG is the stronger pick specifically for capital preservation and lower volatility. DBVT and AZN also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
NVS
Novartis AG
The Defensive Pick

NVS is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.

  • Lower volatility, beta 0.42, Low D/E 79.6%, current ratio 1.12x
  • Beta 0.42 vs NVO's 1.56
Best for: sleep-well-at-night
DBVT
DBV Technologies S.A.
The Momentum Pick

DBVT ranks third and is worth considering specifically for momentum.

  • +110.4% vs NVO's -29.5%
Best for: momentum
AZN
AstraZeneca PLC
The Growth Play

AZN is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 8.6%, EPS growth 190.7%, 3Y rev CAGR 9.8%
  • 268.6% 10Y total return vs NVS's 178.5%
  • 8.6% revenue growth vs DBVT's -100.0%
Best for: growth exposure and long-term compounding
NVO
Novo Nordisk A/S
The Value Pick

NVO carries the broadest edge in this set and is the clearest fit for valuation efficiency.

  • PEG 0.10 vs NVS's 1.08
  • Lower P/E (2.1x vs 21.9x), PEG 0.10 vs 1.03
  • 37.2% margin vs DBVT's 0.3%
  • 4.0% yield, 8-year raise streak, vs MRK's 2.9%, (1 stock pays no dividend)
Best for: valuation efficiency
MRK
Merck & Co., Inc.
The Income Pick

MRK is the clearest fit if your priority is income & stability and defensive.

  • Dividend streak 14 yrs, beta 0.48, yield 2.9%
  • Beta 0.48, yield 2.9%, current ratio 1.54x
Best for: income & stability and defensive
See the full category breakdown
CategoryWinnerWhy
GrowthAZN logoAZN8.6% revenue growth vs DBVT's -100.0%
ValueNVO logoNVOLower P/E (2.1x vs 21.9x), PEG 0.10 vs 1.03
Quality / MarginsNVO logoNVO37.2% margin vs DBVT's 0.3%
Stability / SafetyNVS logoNVSBeta 0.42 vs NVO's 1.56
DividendsNVO logoNVO4.0% yield, 8-year raise streak, vs MRK's 2.9%, (1 stock pays no dividend)
Momentum (1Y)DBVT logoDBVT+110.4% vs NVO's -29.5%
Efficiency (ROA)NVO logoNVO23.3% ROA vs DBVT's -89.0%

NVS vs DBVT vs AZN vs NVO vs MRK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

NVSNovartis AG
FY 2022
Top 20 products
74.3%$32.1B
Rest of portfolio
21.2%$9.2B
Total anti-infectives net sales
2.8%$1.2B
Anti Infectives sold under Sandoz name
1.8%$777M
DBVTDBV Technologies S.A.

Segment breakdown not available.

AZNAstraZeneca PLC
FY 2025
Total Oncology
23.9%$23.7B
CVRM
12.9%$12.8B
Rare Disease
9.2%$9.1B
Farxiga
8.5%$8.4B
Tagrisso
7.3%$7.3B
Imfinzi
6.1%$6.1B
Ultomiris
4.8%$4.7B
Other (22)
27.3%$27.1B
NVONovo Nordisk A/S

Segment breakdown not available.

MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M

NVS vs DBVT vs AZN vs NVO vs MRK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLNVOLAGGINGMRK

Income & Cash Flow (Last 12 Months)

NVO leads this category, winning 4 of 6 comparable metrics.

NVO and DBVT operate at a comparable scale, with $327.8B and $0 in trailing revenue. NVO is the more profitable business, keeping 37.2% of every revenue dollar as net income compared to AZN's 17.2%. On growth, NVO holds the edge at +24.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNVS logoNVSNovartis AGDBVT logoDBVTDBV Technologies …AZN logoAZNAstraZeneca PLCNVO logoNVONovo Nordisk A/SMRK logoMRKMerck & Co., Inc.
RevenueTrailing 12 months$56.1B$0$60.4B$327.8B$64.9B
EBITDAEarnings before interest/tax$22.5B-$112M$20.1B$170.2B$32.4B
Net IncomeAfter-tax profit$13.5B-$168M$10.4B$122.0B$18.3B
Free Cash FlowCash after capex$16.4B-$151M$9.1B$31.0B$12.4B
Gross MarginGross profit ÷ Revenue+75.3%+81.7%+81.8%+74.2%
Operating MarginEBIT ÷ Revenue+30.5%+23.7%+45.3%+41.1%
Net MarginNet income ÷ Revenue+24.1%+17.2%+37.2%+28.1%
FCF MarginFCF ÷ Revenue+29.2%+15.1%+9.5%+19.0%
Rev. Growth (YoY)Latest quarter vs prior year-0.7%+12.5%+24.0%+4.5%
EPS Growth (YoY)Latest quarter vs prior year-9.3%+91.5%+5.3%+67.1%-19.6%
NVO leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

NVO leads this category, winning 4 of 7 comparable metrics.

At 12.6x trailing earnings, NVO trades at a 55% valuation discount to AZN's 27.9x P/E. Adjusting for growth (PEG ratio), NVO offers better value at 0.61x vs NVS's 1.32x — a lower PEG means you pay less per unit of expected earnings growth.

MetricNVS logoNVSNovartis AGDBVT logoDBVTDBV Technologies …AZN logoAZNAstraZeneca PLCNVO logoNVONovo Nordisk A/SMRK logoMRKMerck & Co., Inc.
Market CapShares × price$277.4B$1712.35T$283.0B$203.5B$277.3B
Enterprise ValueMkt cap + debt − cash$303.0B$1712.35T$306.9B$219.9B$313.3B
Trailing P/EPrice ÷ TTM EPS20.22x-0.76x27.91x12.64x15.42x
Forward P/EPrice ÷ next-FY EPS est.16.58x17.74x2.15x21.93x
PEG RatioP/E ÷ EPS growth rate1.32x1.28x0.61x0.73x
EV / EBITDAEnterprise value multiple13.51x15.76x9.34x10.68x
Price / SalesMarket cap ÷ Revenue5.06x4.82x4.19x4.27x
Price / BookPrice ÷ Book value/share6.11x0.66x5.85x6.67x5.35x
Price / FCFMarket cap ÷ FCF15.69x24.05x44.63x22.44x
NVO leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

NVO leads this category, winning 4 of 9 comparable metrics.

NVO delivers a 66.4% return on equity — every $100 of shareholder capital generates $66 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), AZN scores 8/9 vs MRK's 4/9, reflecting strong financial health.

MetricNVS logoNVSNovartis AGDBVT logoDBVTDBV Technologies …AZN logoAZNAstraZeneca PLCNVO logoNVONovo Nordisk A/SMRK logoMRKMerck & Co., Inc.
ROE (TTM)Return on equity+31.4%-130.2%+22.2%+66.4%+36.1%
ROA (TTM)Return on assets+12.1%-89.0%+9.1%+23.3%+14.6%
ROICReturn on invested capital+18.8%+14.9%+36.2%+22.0%
ROCEReturn on capital employed+21.1%-145.7%+17.2%+44.4%+23.8%
Piotroski ScoreFundamental quality 0–964854
Debt / EquityFinancial leverage0.80x0.13x0.61x0.67x0.96x
Net DebtTotal debt minus cash$25.6B-$172M$24.0B$104.5B$36.0B
Cash & Equiv.Liquid assets$11.4B$194M$5.7B$26.5B$14.6B
Total DebtShort + long-term debt$37.0B$22M$29.7B$131.0B$50.5B
Interest CoverageEBIT ÷ Interest expense13.92x-189.82x8.43x18.90x19.68x
NVO leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NVS leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in NVS five years ago would be worth $19,439 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs NVO's -29.5%. The 3-year compound annual growth rate (CAGR) favors NVS at 16.6% vs NVO's -16.0% — a key indicator of consistent wealth creation.

MetricNVS logoNVSNovartis AGDBVT logoDBVTDBV Technologies …AZN logoAZNAstraZeneca PLCNVO logoNVONovo Nordisk A/SMRK logoMRKMerck & Co., Inc.
YTD ReturnYear-to-date+8.4%+4.9%+1.1%-10.2%+6.3%
1-Year ReturnPast 12 months+34.4%+110.4%+33.9%-29.5%+46.1%
3-Year ReturnCumulative with dividends+58.5%+19.7%+30.4%-40.7%+2.9%
5-Year ReturnCumulative with dividends+94.4%-69.1%+82.2%+36.4%+70.2%
10-Year ReturnCumulative with dividends+178.5%-87.0%+268.6%+99.6%+166.5%
CAGR (3Y)Annualised 3-year return+16.6%+6.2%+9.3%-16.0%+0.9%
NVS leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — NVS and MRK each lead in 1 of 2 comparable metrics.

NVS is the less volatile stock with a 0.42 beta — it tends to amplify market swings less than NVO's 1.56 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs NVO's 56.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNVS logoNVSNovartis AGDBVT logoDBVTDBV Technologies …AZN logoAZNAstraZeneca PLCNVO logoNVONovo Nordisk A/SMRK logoMRKMerck & Co., Inc.
Beta (5Y)Sensitivity to S&P 5000.42x1.26x0.67x1.56x0.48x
52-Week HighHighest price in past year$170.46$26.18$212.71$81.44$125.14
52-Week LowLowest price in past year$104.93$7.53$91.44$35.12$73.31
% of 52W HighCurrent price vs 52-week peak+85.3%+76.3%+85.8%+56.2%+89.7%
RSI (14)Momentum oscillator 0–10048.748.139.173.446.7
Avg Volume (50D)Average daily shares traded1.9M252K1.9M18.4M7.3M
Evenly matched — NVS and MRK each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — NVO and MRK each lead in 1 of 2 comparable metrics.

Analyst consensus: NVS as "Hold", DBVT as "Buy", AZN as "Buy", NVO as "Buy", MRK as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs -3.0% for NVS (target: $141). For income investors, NVO offers the higher dividend yield at 4.00% vs AZN's 1.78%.

MetricNVS logoNVSNovartis AGDBVT logoDBVTDBV Technologies …AZN logoAZNAstraZeneca PLCNVO logoNVONovo Nordisk A/SMRK logoMRKMerck & Co., Inc.
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuyBuy
Price TargetConsensus 12-month target$141.00$46.33$211.00$47.00$129.31
# AnalystsCovering analysts2515413937
Dividend YieldAnnual dividend ÷ price+2.8%+1.8%+4.0%+2.9%
Dividend StreakConsecutive years of raises604814
Dividend / ShareAnnual DPS$4.02$3.25$11.64$3.26
Buyback YieldShare repurchases ÷ mkt cap+3.3%0.0%+0.3%+0.1%+1.8%
Evenly matched — NVO and MRK each lead in 1 of 2 comparable metrics.
Key Takeaway

NVO leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). NVS leads in 1 (Total Returns). 2 tied.

Best OverallNovo Nordisk A/S (NVO)Leads 3 of 6 categories
Loading custom metrics...

NVS vs DBVT vs AZN vs NVO vs MRK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is NVS or DBVT or AZN or NVO or MRK a better buy right now?

For growth investors, AstraZeneca PLC (AZN) is the stronger pick with 8.

6% revenue growth year-over-year, versus 1. 2% for Merck & Co. , Inc. (MRK). Novo Nordisk A/S (NVO) offers the better valuation at 12. 6x trailing P/E (2. 1x forward), making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — NVS or DBVT or AZN or NVO or MRK?

On trailing P/E, Novo Nordisk A/S (NVO) is the cheapest at 12.

6x versus AstraZeneca PLC at 27. 9x. On forward P/E, Novo Nordisk A/S is actually cheaper at 2. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Novo Nordisk A/S wins at 0. 10x versus Novartis AG's 1. 08x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — NVS or DBVT or AZN or NVO or MRK?

Over the past 5 years, Novartis AG (NVS) delivered a total return of +94.

4%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: AZN returned +268. 6% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — NVS or DBVT or AZN or NVO or MRK?

By beta (market sensitivity over 5 years), Novartis AG (NVS) is the lower-risk stock at 0.

42β versus Novo Nordisk A/S's 1. 56β — meaning NVO is approximately 267% more volatile than NVS relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — NVS or DBVT or AZN or NVO or MRK?

By revenue growth (latest reported year), AstraZeneca PLC (AZN) is pulling ahead at 8.

6% versus 1. 2% for Merck & Co. , Inc. (MRK). On earnings-per-share growth, the picture is similar: AstraZeneca PLC grew EPS 190. 7% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, NVO leads at 20. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — NVS or DBVT or AZN or NVO or MRK?

Novo Nordisk A/S (NVO) is the more profitable company, earning 33.

1% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 33. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVO leads at 41. 3% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — AZN leads at 81. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is NVS or DBVT or AZN or NVO or MRK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Novo Nordisk A/S (NVO) is the more undervalued stock at a PEG of 0. 10x versus Novartis AG's 1. 08x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Novo Nordisk A/S (NVO) trades at 2. 1x forward P/E versus 21. 9x for Merck & Co. , Inc. — 19. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.

08

Which pays a better dividend — NVS or DBVT or AZN or NVO or MRK?

In this comparison, NVO (4.

0% yield), MRK (2. 9% yield), NVS (2. 8% yield), AZN (1. 8% yield) pay a dividend. DBVT does not pay a meaningful dividend and should not be held primarily for income.

09

Is NVS or DBVT or AZN or NVO or MRK better for a retirement portfolio?

For long-horizon retirement investors, Novartis AG (NVS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

42), 2. 8% yield, +178. 5% 10Y return). Both have compounded well over 10 years (NVS: +178. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between NVS and DBVT and AZN and NVO and MRK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: NVS is a large-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; AZN is a large-cap quality compounder stock; NVO is a large-cap deep-value stock; MRK is a large-cap deep-value stock. NVS, AZN, NVO, MRK pay a dividend while DBVT does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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