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ONCO vs DBVT vs CRVS vs AGEN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
ONCO vs DBVT vs CRVS vs AGEN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $1M | $1712.35T | $1.23B | $132M |
| Revenue (TTM) | $815K | $0.00 | $0.00 | $114M |
| Net Income (TTM) | $-14M | $-168M | $-44M | $115K |
| Gross Margin | 77.6% | — | — | 35.7% |
| Operating Margin | -21.9% | — | — | -17.7% |
| Forward P/E | — | — | — | 2.9x |
| Total Debt | $49K | $22M | $937K | $10M |
| Cash & Equiv. | $5M | $194M | $5M | $3M |
ONCO vs DBVT vs CRVS vs AGEN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 22 | May 26 | Return |
|---|---|---|---|
| Onconetix, Inc. (ONCO) | 100 | 0.0 | -100.0% |
| DBV Technologies S.… (DBVT) | 100 | 147.2 | +47.2% |
| Corvus Pharmaceutic… (CRVS) | 100 | 878.5 | +778.5% |
| Agenus Inc. (AGEN) | 100 | 7.1 | -92.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ONCO vs DBVT vs CRVS vs AGEN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ONCO is the clearest fit if your priority is income & stability.
- Dividend streak 0 yrs, beta 1.41, yield 30.9%
- 30.9% yield; the other 3 pay no meaningful dividend
DBVT is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 1.26, Low D/E 12.8%, current ratio 3.67x
- Beta 1.26, current ratio 3.67x
- Beta 1.26 vs AGEN's 2.72
CRVS carries the broadest edge in this set and is the clearest fit for long-term compounding.
- 17.1% 10Y total return vs DBVT's -87.0%
- 3.5% margin vs ONCO's -17.2%
- +355.9% vs ONCO's -98.6%
AGEN is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 10.4%, EPS growth 100.0%, 3Y rev CAGR 5.2%
- 10.4% revenue growth vs DBVT's -100.0%
- 0.1% ROA vs DBVT's -89.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 10.4% revenue growth vs DBVT's -100.0% | |
| Quality / Margins | 3.5% margin vs ONCO's -17.2% | |
| Stability / Safety | Beta 1.26 vs AGEN's 2.72 | |
| Dividends | 30.9% yield; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +355.9% vs ONCO's -98.6% | |
| Efficiency (ROA) | 0.1% ROA vs DBVT's -89.0% |
ONCO vs DBVT vs CRVS vs AGEN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ONCO vs DBVT vs CRVS vs AGEN — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
AGEN leads in 3 of 6 categories
ONCO leads 1 • CRVS leads 1 • DBVT leads 1
Explore the data ↓Income & Cash Flow (Last 12 Months)
AGEN leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
AGEN and CRVS operate at a comparable scale, with $114M and $0 in trailing revenue. AGEN is the more profitable business, keeping 0.1% of every revenue dollar as net income compared to ONCO's -17.2%. On growth, AGEN holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $815,371 | $0 | $0 | $114M |
| EBITDAEarnings before interest/tax | -$18M | -$112M | -$48M | -$10M |
| Net IncomeAfter-tax profit | -$14M | -$168M | -$44M | $115,000 |
| Free Cash FlowCash after capex | -$10M | -$151M | -$35M | -$159M |
| Gross MarginGross profit ÷ Revenue | +77.6% | — | — | +35.7% |
| Operating MarginEBIT ÷ Revenue | -21.9% | — | — | -17.7% |
| Net MarginNet income ÷ Revenue | -17.2% | — | — | +0.1% |
| FCF MarginFCF ÷ Revenue | -11.9% | — | — | -139.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | -57.4% | — | — | +27.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +120.9% | +91.5% | -15.4% | +85.3% |
Valuation Metrics
AGEN leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1M | $1712.35T | $1.2B | $132M |
| Enterprise ValueMkt cap + debt − cash | -$4M | $1712.35T | $1.2B | $140M |
| Trailing P/EPrice ÷ TTM EPS | -0.09x | -0.76x | -27.53x | -1102.94x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 2.94x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 1.70x | — | — | 1.16x |
| Price / BookPrice ÷ Book value/share | 0.08x | 0.66x | 19.01x | — |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
ONCO leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
CRVS delivers a -38.9% return on equity — every $100 of shareholder capital generates $-39 in annual profit, vs $-190 for ONCO. ONCO carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DBVT's 0.13x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs CRVS's 3/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -189.8% | -130.2% | -38.9% | — |
| ROA (TTM)Return on assets | -68.0% | -89.0% | -35.7% | +0.1% |
| ROICReturn on invested capital | -32.8% | — | -78.1% | — |
| ROCEReturn on capital employed | -49.4% | -145.7% | -90.2% | — |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 3 | 6 |
| Debt / EquityFinancial leverage | 0.00x | 0.13x | 0.02x | — |
| Net DebtTotal debt minus cash | -$5M | -$172M | -$4M | $7M |
| Cash & Equiv.Liquid assets | $5M | $194M | $5M | $3M |
| Total DebtShort + long-term debt | $48,774 | $22M | $937,000 | $10M |
| Interest CoverageEBIT ÷ Interest expense | -26.95x | -189.82x | -18.29x | 1.11x |
Total Returns (Dividends Reinvested)
CRVS leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CRVS five years ago would be worth $50,137 today (with dividends reinvested), compared to $0 for ONCO. Over the past 12 months, CRVS leads with a +355.9% total return vs ONCO's -98.6%. The 3-year compound annual growth rate (CAGR) favors CRVS at 123.9% vs ONCO's -97.2% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -95.0% | +4.9% | +99.3% | +16.1% |
| 1-Year ReturnPast 12 months | -98.6% | +110.4% | +355.9% | +27.1% |
| 3-Year ReturnCumulative with dividends | -100.0% | +19.7% | +1022.3% | -88.2% |
| 5-Year ReturnCumulative with dividends | -100.0% | -69.1% | +401.4% | -93.9% |
| 10-Year ReturnCumulative with dividends | -100.0% | -87.0% | +17.1% | -94.3% |
| CAGR (3Y)Annualised 3-year return | -97.2% | +6.2% | +123.9% | -51.0% |
Risk & Volatility
DBVT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
DBVT is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DBVT currently trades 76.3% from its 52-week high vs ONCO's 0.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.28x | 1.26x | 1.57x | 2.58x |
| 52-Week HighHighest price in past year | $74.30 | $26.18 | $26.95 | $7.34 |
| 52-Week LowLowest price in past year | $0.37 | $7.53 | $3.17 | $2.71 |
| % of 52W HighCurrent price vs 52-week peak | +0.5% | +76.3% | +54.1% | +51.1% |
| RSI (14)Momentum oscillator 0–100 | 28.8 | 48.1 | 49.2 | 48.8 |
| Avg Volume (50D)Average daily shares traded | 9.4M | 252K | 1.2M | 814K |
Analyst Outlook
AGEN leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", CRVS as "Buy", AGEN as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 95.5% for AGEN (target: $7). ONCO is the only dividend payer here at 30.89% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $46.33 | $33.17 | $7.33 |
| # AnalystsCovering analysts | — | 15 | 13 | 11 |
| Dividend YieldAnnual dividend ÷ price | +30.9% | — | — | — |
| Dividend StreakConsecutive years of raises | 0 | 0 | — | 1 |
| Dividend / ShareAnnual DPS | $0.12 | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.1% |
AGEN leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ONCO leads in 1 (Profitability & Efficiency).
ONCO vs DBVT vs CRVS vs AGEN: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is ONCO or DBVT or CRVS or AGEN a better buy right now?
For growth investors, Agenus Inc.
(AGEN) is the stronger pick with 10. 4% revenue growth year-over-year, versus -67. 7% for Onconetix, Inc. (ONCO). Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ONCO or DBVT or CRVS or AGEN?
Over the past 5 years, Corvus Pharmaceuticals, Inc.
(CRVS) delivered a total return of +401. 4%, compared to -100. 0% for Onconetix, Inc. (ONCO). Over 10 years, the gap is even starker: CRVS returned +24. 8% versus ONCO's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ONCO or DBVT or CRVS or AGEN?
By beta (market sensitivity over 5 years), DBV Technologies S.
A. (DBVT) is the lower-risk stock at 1. 26β versus Agenus Inc. 's 2. 58β — meaning AGEN is approximately 105% more volatile than DBVT relative to the S&P 500. On balance sheet safety, Onconetix, Inc. (ONCO) carries a lower debt/equity ratio of 0% versus 13% for DBV Technologies S. A. — giving it more financial flexibility in a downturn.
04Which is growing faster — ONCO or DBVT or CRVS or AGEN?
By revenue growth (latest reported year), Agenus Inc.
(AGEN) is pulling ahead at 10. 4% versus -67. 7% for Onconetix, Inc. (ONCO). On earnings-per-share growth, the picture is similar: Agenus Inc. grew EPS 100. 0% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ONCO or DBVT or CRVS or AGEN?
Agenus Inc.
(AGEN) is the more profitable company, earning 0. 1% net margin versus -1721. 0% for Onconetix, Inc. — meaning it keeps 0. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -778. 2% for ONCO. At the gross margin level — before operating expenses — AGEN leads at 90. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is ONCO or DBVT or CRVS or AGEN more undervalued right now?
Analyst consensus price targets imply the most upside for DBVT: 131.
8% to $46. 33.
07Which pays a better dividend — ONCO or DBVT or CRVS or AGEN?
In this comparison, ONCO (30.
9% yield) pays a dividend. DBVT, CRVS, AGEN do not pay a meaningful dividend and should not be held primarily for income.
08Is ONCO or DBVT or CRVS or AGEN better for a retirement portfolio?
For long-horizon retirement investors, Onconetix, Inc.
(ONCO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 28), 30. 9% yield). Agenus Inc. (AGEN) carries a higher beta of 2. 58 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ONCO: -100. 0%, AGEN: -94. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between ONCO and DBVT and CRVS and AGEN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ONCO is a small-cap income-oriented stock; DBVT is a mega-cap quality compounder stock; CRVS is a small-cap quality compounder stock; AGEN is a small-cap quality compounder stock. ONCO pays a dividend while DBVT, CRVS, AGEN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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