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ONMD vs PHVS vs NVCR vs KALV vs PRAX
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Instruments & Supplies
Biotechnology
Biotechnology
ONMD vs PHVS vs NVCR vs KALV vs PRAX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Healthcare Information Services | Biotechnology | Medical - Instruments & Supplies | Biotechnology | Biotechnology |
| Market Cap | $32M | $1.93B | $1.92B | $1.37B | $9.63B |
| Revenue (TTM) | $1M | $0.00 | $674M | $15M | $-92K |
| Net Income (TTM) | $-3M | $-166M | $-173M | $-210M | $-327M |
| Gross Margin | -37.0% | — | 75.2% | -17.2% | — |
| Operating Margin | -7.1% | — | -27.2% | -13.4% | — |
| Total Debt | $570K | $861K | $290M | $6M | $110K |
| Cash & Equiv. | $585K | $281M | $103M | $99M | $357M |
ONMD vs PHVS vs NVCR vs KALV vs PRAX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 21 | May 26 | Return |
|---|---|---|---|
| OneMedNet Corporati… (ONMD) | 100 | 9.9 | -90.1% |
| Pharvaris N.V. (PHVS) | 100 | 159.3 | +59.3% |
| NovoCure Limited (NVCR) | 100 | 7.6 | -92.4% |
| KalVista Pharmaceut… (KALV) | 100 | 111.5 | +11.5% |
| Praxis Precision Me… (PRAX) | 100 | 121.5 | +21.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ONMD vs PHVS vs NVCR vs KALV vs PRAX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ONMD carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.37
- Rev growth 111.4%, EPS growth 83.3%, 3Y rev CAGR 5.6%
- 111.4% revenue growth vs PRAX's -100.0%
- Beta 0.37 vs NVCR's 2.20
PHVS is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 1.02, Low D/E 0.3%, current ratio 12.60x
- Beta 1.02, current ratio 12.60x
NVCR ranks third and is worth considering specifically for efficiency.
- -16.5% ROA vs ONMD's -145.0%
KALV is the clearest fit if your priority is long-term compounding.
- 154.5% 10Y total return vs PHVS's 2.3%
PRAX is the #2 pick in this set and the best alternative if quality and momentum is your priority.
- 2.4% margin vs KALV's -13.9%
- +7.7% vs NVCR's +1.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 111.4% revenue growth vs PRAX's -100.0% | |
| Quality / Margins | 2.4% margin vs KALV's -13.9% | |
| Stability / Safety | Beta 0.37 vs NVCR's 2.20 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +7.7% vs NVCR's +1.1% | |
| Efficiency (ROA) | -16.5% ROA vs ONMD's -145.0% |
ONMD vs PHVS vs NVCR vs KALV vs PRAX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
ONMD vs PHVS vs NVCR vs KALV vs PRAX — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NVCR leads in 1 of 6 categories
PRAX leads 1 • ONMD leads 0 • PHVS leads 0 • KALV leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NVCR leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR and PRAX operate at a comparable scale, with $674M and -$92,000 in trailing revenue. Profitability is closely matched — net margins range from -25.7% (NVCR) to -13.9% (KALV). On growth, ONMD holds the edge at +33.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $1M | $0 | $674M | $15M | -$92,000 |
| EBITDAEarnings before interest/tax | -$10M | -$86M | -$165M | -$202M | -$357M |
| Net IncomeAfter-tax profit | -$3M | -$166M | -$173M | -$210M | -$327M |
| Free Cash FlowCash after capex | -$8M | -$134M | -$48M | -$160M | -$283M |
| Gross MarginGross profit ÷ Revenue | -37.0% | — | +75.2% | -17.2% | — |
| Operating MarginEBIT ÷ Revenue | -7.1% | — | -27.2% | -13.4% | — |
| Net MarginNet income ÷ Revenue | -2.1% | — | -25.7% | -13.9% | — |
| FCF MarginFCF ÷ Revenue | -5.5% | — | -7.1% | -10.6% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | +33.2% | — | +12.3% | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | +26.3% | +22.1% | -100.0% | -1.1% | +2.7% |
Valuation Metrics
Evenly matched — PHVS and NVCR and PRAX each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $32M | $1.9B | $1.9B | $1.4B | $9.6B |
| Enterprise ValueMkt cap + debt − cash | $32M | $1.6B | $2.1B | $1.3B | $9.3B |
| Trailing P/EPrice ÷ TTM EPS | -16.29x | -10.18x | -13.80x | -7.24x | -24.72x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 23.58x | — | 2.92x | — | — |
| Price / BookPrice ÷ Book value/share | — | 5.10x | 5.51x | 13.91x | 8.54x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
Evenly matched — NVCR and PRAX each lead in 4 of 9 comparable metrics.
Profitability & Efficiency
PRAX delivers a -43.0% return on equity — every $100 of shareholder capital generates $-43 in annual profit, vs $-3 for KALV. PRAX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), ONMD scores 5/9 vs PHVS's 1/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -53.2% | -50.8% | -2.8% | -43.0% |
| ROA (TTM)Return on assets | -145.0% | -49.0% | -16.5% | -77.7% | -40.2% |
| ROICReturn on invested capital | — | — | -16.4% | -152.3% | -65.0% |
| ROCEReturn on capital employed | — | -44.7% | -28.9% | -89.9% | -49.3% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 1 | 5 | 2 | 3 |
| Debt / EquityFinancial leverage | — | 0.00x | 0.85x | 0.07x | 0.00x |
| Net DebtTotal debt minus cash | -$15,000 | -$280M | $187M | -$92M | -$357M |
| Cash & Equiv.Liquid assets | $585,000 | $281M | $103M | $99M | $357M |
| Total DebtShort + long-term debt | $570,000 | $861,470 | $290M | $6M | $110,000 |
| Interest CoverageEBIT ÷ Interest expense | -40.79x | — | -96.80x | -13.75x | — |
Total Returns (Dividends Reinvested)
PRAX leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in PHVS five years ago would be worth $13,115 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, PRAX leads with a +775.0% total return vs NVCR's +1.1%. The 3-year compound annual growth rate (CAGR) favors PRAX at 174.9% vs ONMD's -55.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -19.9% | +12.1% | +28.3% | +72.8% | +16.4% |
| 1-Year ReturnPast 12 months | +151.3% | +73.6% | +1.1% | +118.1% | +775.0% |
| 3-Year ReturnCumulative with dividends | -90.9% | +220.5% | -75.7% | +180.1% | +1976.5% |
| 5-Year ReturnCumulative with dividends | -90.1% | +31.2% | -91.3% | +5.9% | -20.8% |
| 10-Year ReturnCumulative with dividends | -90.1% | +2.3% | +30.3% | +154.5% | -20.1% |
| CAGR (3Y)Annualised 3-year return | -55.0% | +47.4% | -37.6% | +41.0% | +174.9% |
Risk & Volatility
Evenly matched — ONMD and KALV each lead in 1 of 2 comparable metrics.
Risk & Volatility
ONMD is the less volatile stock with a 0.37 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KALV currently trades 99.5% from its 52-week high vs ONMD's 23.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.37x | 1.02x | 2.20x | 0.82x | 1.55x |
| 52-Week HighHighest price in past year | $4.22 | $31.12 | $20.06 | $26.84 | $356.00 |
| 52-Week LowLowest price in past year | $0.31 | $14.59 | $9.82 | $9.83 | $35.18 |
| % of 52W HighCurrent price vs 52-week peak | +23.2% | +95.4% | +83.9% | +99.5% | +93.6% |
| RSI (14)Momentum oscillator 0–100 | 50.6 | 57.2 | 69.8 | 75.4 | 55.6 |
| Avg Volume (50D)Average daily shares traded | 5.2M | 227K | 1.5M | 3.0M | 378K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: PHVS as "Buy", NVCR as "Buy", KALV as "Buy", PRAX as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 6.7% for KALV (target: $29).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $43.67 | $33.50 | $28.50 | $544.40 |
| # AnalystsCovering analysts | — | 11 | 15 | 13 | 16 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
NVCR leads in 1 of 6 categories (Income & Cash Flow). PRAX leads in 1 (Total Returns). 3 tied.
ONMD vs PHVS vs NVCR vs KALV vs PRAX: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ONMD or PHVS or NVCR or KALV or PRAX a better buy right now?
For growth investors, OneMedNet Corporation (ONMD) is the stronger pick with 111.
4% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). Analysts rate Pharvaris N. V. (PHVS) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ONMD or PHVS or NVCR or KALV or PRAX?
Over the past 5 years, Pharvaris N.
V. (PHVS) delivered a total return of +31. 2%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: KALV returned +154. 5% versus ONMD's -90. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ONMD or PHVS or NVCR or KALV or PRAX?
By beta (market sensitivity over 5 years), OneMedNet Corporation (ONMD) is the lower-risk stock at 0.
37β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 491% more volatile than ONMD relative to the S&P 500. On balance sheet safety, Praxis Precision Medicines, Inc. (PRAX) carries a lower debt/equity ratio of 0% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
04Which is growing faster — ONMD or PHVS or NVCR or KALV or PRAX?
By revenue growth (latest reported year), OneMedNet Corporation (ONMD) is pulling ahead at 111.
4% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: OneMedNet Corporation grew EPS 83. 3% year-over-year, compared to -32. 0% for Praxis Precision Medicines, Inc.. Over a 3-year CAGR, NVCR leads at 6. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ONMD or PHVS or NVCR or KALV or PRAX?
Pharvaris N.
V. (PHVS) is the more profitable company, earning 0. 0% net margin versus -1391. 1% for KalVista Pharmaceuticals, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PHVS leads at 0. 0% versus -1343. 0% for KALV. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ONMD or PHVS or NVCR or KALV or PRAX?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ONMD or PHVS or NVCR or KALV or PRAX better for a retirement portfolio?
For long-horizon retirement investors, OneMedNet Corporation (ONMD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
37)). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ONMD: -90. 1%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ONMD and PHVS and NVCR and KALV and PRAX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ONMD is a small-cap high-growth stock; PHVS is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock; KALV is a small-cap quality compounder stock; PRAX is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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