Biotechnology
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5 / 10Stock Comparison
PRTC vs ROIV vs ATAI vs CMPS vs RXRX
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Pharmaceuticals
Medical - Care Facilities
Biotechnology
PRTC vs ROIV vs ATAI vs CMPS vs RXRX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Medical - Pharmaceuticals | Medical - Care Facilities | Biotechnology |
| Market Cap | $41M | $20.51B | $964M | $902M | $1.46B |
| Revenue (TTM) | $9M | $13M | $3M | $0.00 | $66M |
| Net Income (TTM) | $-56M | $-809M | $-154M | $-288M | $-560M |
| Gross Margin | -196.2% | 91.2% | -259.1% | — | -34.4% |
| Operating Margin | -26.2% | -91.3% | -34.6% | — | -8.8% |
| Total Debt | $20M | $100M | $25M | $21M | $78M |
| Cash & Equiv. | $254M | $2.72B | $18M | $150M | $743M |
PRTC vs ROIV vs ATAI vs CMPS vs RXRX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 21 | May 26 | Return |
|---|---|---|---|
| PureTech Health plc (PRTC) | 100 | 34.6 | -65.4% |
| Roivant Sciences Lt… (ROIV) | 100 | 285.9 | +185.9% |
| Atai Beckley N.V (ATAI) | 100 | 21.7 | -78.3% |
| COMPASS Pathways plc (CMPS) | 100 | 24.6 | -75.4% |
| Recursion Pharmaceu… (RXRX) | 100 | 9.0 | -91.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: PRTC vs ROIV vs ATAI vs CMPS vs RXRX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
PRTC carries the broadest edge in this set and is the clearest fit for income & stability and defensive.
- Dividend streak 1 yrs, beta 0.51
- Beta 0.51, current ratio 6.59x
- Beta 0.51 vs RXRX's 3.18, lower leverage
- -9.9% ROA vs CMPS's -106.8%
ROIV is the clearest fit if your priority is long-term compounding and sleep-well-at-night.
- 171.9% 10Y total return vs PRTC's -55.9%
- Lower volatility, beta 0.95, Low D/E 1.9%, current ratio 33.47x
ATAI is the #2 pick in this set and the best alternative if momentum is your priority.
- +188.5% vs RXRX's -22.0%
CMPS ranks third and is worth considering specifically for quality.
- 1.3% margin vs ROIV's -60.8%
RXRX is the clearest fit if your priority is growth exposure.
- Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
- 26.9% revenue growth vs CMPS's -85.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 26.9% revenue growth vs CMPS's -85.7% | |
| Quality / Margins | 1.3% margin vs ROIV's -60.8% | |
| Stability / Safety | Beta 0.51 vs RXRX's 3.18, lower leverage | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +188.5% vs RXRX's -22.0% | |
| Efficiency (ROA) | -9.9% ROA vs CMPS's -106.8% |
PRTC vs ROIV vs ATAI vs CMPS vs RXRX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
PRTC vs ROIV vs ATAI vs CMPS vs RXRX — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
PRTC leads in 2 of 6 categories
RXRX leads 1 • ROIV leads 1 • ATAI leads 0 • CMPS leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
RXRX leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RXRX and CMPS operate at a comparable scale, with $66M and $0 in trailing revenue. PRTC is the more profitable business, keeping -6.2% of every revenue dollar as net income compared to ROIV's -60.8%. On growth, ATAI holds the edge at +17.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $9M | $13M | $3M | $0 | $66M |
| EBITDAEarnings before interest/tax | -$228M | -$1.2B | -$103M | -$179M | -$521M |
| Net IncomeAfter-tax profit | -$56M | -$809M | -$154M | -$288M | -$560M |
| Free Cash FlowCash after capex | -$219M | -$767M | -$90M | -$157M | -$326M |
| Gross MarginGross profit ÷ Revenue | -196.2% | +91.2% | -2.6% | — | -34.4% |
| Operating MarginEBIT ÷ Revenue | -26.2% | -91.3% | -34.6% | — | -8.8% |
| Net MarginNet income ÷ Revenue | -6.2% | -60.8% | -51.1% | — | -8.4% |
| FCF MarginFCF ÷ Revenue | -24.4% | -57.6% | -29.9% | — | -4.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | -30.5% | -77.8% | +17.7% | — | -56.1% |
| EPS Growth (YoY)Latest quarter vs prior year | -8.7% | -2.7% | -75.0% | -58.7% | +56.0% |
Valuation Metrics
PRTC leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $41M | $20.5B | $964M | $902M | $1.5B |
| Enterprise ValueMkt cap + debt − cash | -$193M | $17.9B | $971M | $774M | $797M |
| Trailing P/EPrice ÷ TTM EPS | -0.37x | -117.83x | -4.31x | -3.05x | -2.27x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 8.79x | 706.10x | 3130.37x | — | 19.58x |
| Price / BookPrice ÷ Book value/share | 0.13x | 3.95x | 5.51x | — | 1.29x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
PRTC leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
PRTC delivers a -16.1% return on equity — every $100 of shareholder capital generates $-16 in annual profit, vs $-3 for CMPS. ROIV carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to ATAI's 0.21x. On the Piotroski fundamental quality scale (0–9), PRTC scores 5/9 vs CMPS's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -16.1% | -16.3% | -96.4% | -3.4% | -54.3% |
| ROA (TTM)Return on assets | -9.9% | -15.5% | -64.3% | -106.8% | -40.6% |
| ROICReturn on invested capital | -66.9% | -50.4% | -45.0% | — | -95.8% |
| ROCEReturn on capital employed | -18.8% | -16.4% | -50.4% | -2.5% | -50.1% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 5 | 2 | 2 | 4 |
| Debt / EquityFinancial leverage | 0.06x | 0.02x | 0.21x | — | 0.07x |
| Net DebtTotal debt minus cash | -$234M | -$2.6B | $7M | -$129M | -$665M |
| Cash & Equiv.Liquid assets | $254M | $2.7B | $18M | $150M | $743M |
| Total DebtShort + long-term debt | $20M | $100M | $25M | $21M | $78M |
| Interest CoverageEBIT ÷ Interest expense | -1.16x | — | -68.93x | -52.40x | -336.46x |
Total Returns (Dividends Reinvested)
ROIV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ROIV five years ago would be worth $28,537 today (with dividends reinvested), compared to $1,179 for RXRX. Over the past 12 months, ATAI leads with a +188.5% total return vs RXRX's -22.0%. The 3-year compound annual growth rate (CAGR) favors ROIV at 46.7% vs RXRX's -16.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +2.0% | +29.0% | +3.6% | +43.4% | -22.1% |
| 1-Year ReturnPast 12 months | -2.6% | +153.2% | +188.5% | +151.1% | -22.0% |
| 3-Year ReturnCumulative with dividends | -41.3% | +215.6% | +99.5% | +11.0% | -41.6% |
| 5-Year ReturnCumulative with dividends | -70.1% | +185.4% | -79.8% | -72.4% | -88.2% |
| 10-Year ReturnCumulative with dividends | -55.9% | +171.9% | -47.7% | -67.6% | -81.8% |
| CAGR (3Y)Annualised 3-year return | -16.3% | +46.7% | +25.9% | +3.5% | -16.4% |
Risk & Volatility
Evenly matched — PRTC and ROIV each lead in 1 of 2 comparable metrics.
Risk & Volatility
PRTC is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ROIV currently trades 93.2% from its 52-week high vs RXRX's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.51x | 0.95x | 1.48x | 1.33x | 3.18x |
| 52-Week HighHighest price in past year | $19.92 | $30.33 | $6.75 | $10.21 | $7.18 |
| 52-Week LowLowest price in past year | $14.50 | $10.58 | $1.29 | $2.25 | $2.80 |
| % of 52W HighCurrent price vs 52-week peak | +85.2% | +93.2% | +59.4% | +92.0% | +45.5% |
| RSI (14)Momentum oscillator 0–100 | 48.2 | 54.8 | 51.5 | 68.1 | 49.5 |
| Avg Volume (50D)Average daily shares traded | 8K | 4.8M | 6.0M | 3.7M | 12.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: PRTC as "Buy", ROIV as "Buy", ATAI as "Buy", CMPS as "Buy", RXRX as "Hold". Consensus price targets imply 236.4% upside for RXRX (target: $11) vs 17.4% for ROIV (target: $33).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | $57.00 | $33.20 | $12.00 | $17.83 | $11.00 |
| # AnalystsCovering analysts | 2 | 14 | 4 | 13 | 10 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | 1 | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +5.0% | +6.3% | 0.0% | 0.0% | 0.0% |
PRTC leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). RXRX leads in 1 (Income & Cash Flow). 1 tied.
PRTC vs ROIV vs ATAI vs CMPS vs RXRX: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is PRTC or ROIV or ATAI or CMPS or RXRX a better buy right now?
For growth investors, Recursion Pharmaceuticals, Inc.
(RXRX) is the stronger pick with 26. 9% revenue growth year-over-year, versus -11. 2% for Roivant Sciences Ltd. (ROIV). Analysts rate PureTech Health plc (PRTC) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — PRTC or ROIV or ATAI or CMPS or RXRX?
Over the past 5 years, Roivant Sciences Ltd.
(ROIV) delivered a total return of +185. 4%, compared to -88. 2% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: ROIV returned +171. 9% versus RXRX's -81. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — PRTC or ROIV or ATAI or CMPS or RXRX?
By beta (market sensitivity over 5 years), PureTech Health plc (PRTC) is the lower-risk stock at 0.
51β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 525% more volatile than PRTC relative to the S&P 500. On balance sheet safety, Roivant Sciences Ltd. (ROIV) carries a lower debt/equity ratio of 2% versus 21% for Atai Beckley N. V — giving it more financial flexibility in a downturn.
04Which is growing faster — PRTC or ROIV or ATAI or CMPS or RXRX?
By revenue growth (latest reported year), Recursion Pharmaceuticals, Inc.
(RXRX) is pulling ahead at 26. 9% versus -11. 2% for Roivant Sciences Ltd. (ROIV). On earnings-per-share growth, the picture is similar: Recursion Pharmaceuticals, Inc. grew EPS 14. 8% year-over-year, compared to -24. 0% for PureTech Health plc. Over a 3-year CAGR, PRTC leads at 30. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — PRTC or ROIV or ATAI or CMPS or RXRX?
COMPASS Pathways plc (CMPS) is the more profitable company, earning 0.
0% net margin versus -484. 6% for Atai Beckley N. V — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CMPS leads at 0. 0% versus -333. 4% for ATAI. At the gross margin level — before operating expenses — PRTC leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — PRTC or ROIV or ATAI or CMPS or RXRX?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is PRTC or ROIV or ATAI or CMPS or RXRX better for a retirement portfolio?
For long-horizon retirement investors, PureTech Health plc (PRTC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
51)). Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 3. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PRTC: -55. 9%, RXRX: -81. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between PRTC and ROIV and ATAI and CMPS and RXRX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: PRTC is a small-cap quality compounder stock; ROIV is a mid-cap quality compounder stock; ATAI is a small-cap quality compounder stock; CMPS is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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