QNTM
Quantum BioPharma Ltd.
Drug Manufacturers - Specialty & Generic
Market Cap$21M
5Y Perf.-97.5%
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Stock Comparison
QNTM vs SAVA vs ANVS vs NRXP
Revenue, margins, valuation, and 5-year total return — side by side.
SAVA
Cassava Sciences, Inc.
Biotechnology
Market Cap$94M
5Y Perf.+645.8%
ANVS
Annovis Bio, Inc.
Biotechnology
Market Cap$62M
5Y Perf.-48.6%
NRXP
NRx Pharmaceuticals, Inc.
Biotechnology
Market Cap$85M
5Y Perf.-97.2%
QNTM vs SAVA vs ANVS vs NRXP — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | QNTM | SAVA | ANVS | NRXP |
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $21M | $94M | $62M | $85M |
| Revenue (TTM) | $0.00 | $0.00 | $0.00 | $242K |
| Net Income (TTM) | $-26M | $-106M | $-29M | $-38M |
| Gross Margin | — | — | — | 59.5% |
| Operating Margin | — | — | — | -63.0% |
| Total Debt | $2M | $0.00 | $0.00 | $631K |
| Cash & Equiv. | $2M | $129M | $19.53B | $8M |
QNTM vs SAVA vs ANVS vs NRXP — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
QNTM
SAVA
ANVS
NRXP
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Quantum BioPharma L… (QNTM) | 100 | 2.5 | -97.5% |
| Cassava Sciences, I… (SAVA) | 100 | 745.8 | +645.8% |
| Annovis Bio, Inc. (ANVS) | 100 | 51.4 | -48.6% |
| NRx Pharmaceuticals… (NRXP) | 100 | 2.8 | -97.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: QNTM vs SAVA vs ANVS vs NRXP
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: ANVS leads in 2 of 6 categories, making it the strongest pick for growth and revenue expansion and operational efficiency and capital deployment. Quantum BioPharma Ltd. is the stronger pick specifically for capital preservation and lower volatility. SAVA and NRXP also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
QNTM
Quantum BioPharma Ltd.
The Income Pick
QNTM is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.
- beta 0.98
- Lower volatility, beta 0.98, Low D/E 36.8%, current ratio 1.07x
- Beta 0.98, current ratio 1.07x
- Beta 0.98 vs ANVS's 2.16
Best for: income & stability and sleep-well-at-night
SAVA
Cassava Sciences, Inc.
The Long-Run Compounder
SAVA is the clearest fit if your priority is long-term compounding.
- -19.5% 10Y total return vs ANVS's -76.3%
- 5.4% margin vs NRXP's -157.3%
Best for: long-term compounding
ANVS
Annovis Bio, Inc.
The Growth Play
ANVS carries the broadest edge in this set and is the clearest fit for growth exposure.
- EPS growth 99.9%
- 100.4% revenue growth vs SAVA's -5.4%
- -0.5% ROA vs NRXP's -489.9%
Best for: growth exposure
NRXP
NRx Pharmaceuticals, Inc.
The Momentum Pick
NRXP is the clearest fit if your priority is momentum.
- +55.3% vs QNTM's -40.4%
Best for: momentum
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | ANVS | 100.4% revenue growth vs SAVA's -5.4% |
| Quality / Margins | SAVA | 5.4% margin vs NRXP's -157.3% |
| Stability / Safety | QNTM | Beta 0.98 vs ANVS's 2.16 |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | NRXP | +55.3% vs QNTM's -40.4% |
| Efficiency (ROA) | ANVS | -0.5% ROA vs NRXP's -489.9% |
QNTM vs SAVA vs ANVS vs NRXP — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
FY 2025
QNTM vs SAVA vs ANVS vs NRXP — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLQNTMLAGGINGNRXP
Who Leads Where
QNTM leads in 1 of 6 categories
ANVS leads 1 • SAVA leads 1 • NRXP leads 0 • 2 tied
Explore the data ↓NRXPNRx Pharmaceuticals, …
0leads
ANVSAnnovis Bio, Inc.
1leads
SAVACassava Sciences, Inc.
1leads
QNTMQuantum BioPharma Ltd.
1leads
6 Total Categories
CATEGORYLEADERvs SAVAvs ANVSMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
QNTM1/1
Valuation MetricsMultiples, price ratios, and targets
Tied
—
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
ANVS5/8
Total Returns1Y, 3Y, 5Y total returns with dividends
SAVA4/6
Risk & VolatilityBeta, volatility, and downside exposure
Tied
—
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
QNTM leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
NRXP and ANVS operate at a comparable scale, with $242,000 and $0 in trailing revenue.
| Metric | QNTMQuantum BioPharma… | SAVACassava Sciences,… | ANVSAnnovis Bio, Inc. | NRXPNRx Pharmaceutica… |
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $0 | $242,000 |
| EBITDAEarnings before interest/tax | -$15M | -$110M | -$30M | -$31M |
| Net IncomeAfter-tax profit | -$26M | -$106M | -$29M | -$38M |
| Free Cash FlowCash after capex | -$8M | -$84M | -$853M | -$12M |
| Gross MarginGross profit ÷ Revenue | — | — | — | +59.5% |
| Operating MarginEBIT ÷ Revenue | — | — | — | -63.0% |
| Net MarginNet income ÷ Revenue | — | — | — | -157.3% |
| FCF MarginFCF ÷ Revenue | — | — | — | -49.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | +84.9% | +62.1% | +16.7% | -80.0% |
QNTM leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
Evenly matched — SAVA and ANVS each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | QNTMQuantum BioPharma… | SAVACassava Sciences,… | ANVSAnnovis Bio, Inc. | NRXPNRx Pharmaceutica… |
|---|---|---|---|---|
| Market CapShares × price | $21M | $94M | $62M | $85M |
| Enterprise ValueMkt cap + debt − cash | $21M | -$34M | -$19.5B | $78M |
| Trailing P/EPrice ÷ TTM EPS | -0.62x | -3.76x | -1.62x | -2.28x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — | — | 69.15x |
| Price / BookPrice ÷ Book value/share | 3.23x | 0.63x | 0.00x | — |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Evenly matched — SAVA and ANVS each lead in 1 of 2 comparable metrics.
Profitability & Efficiency
ANVS leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
ANVS delivers a -0.7% return on equity — every $100 of shareholder capital generates $-1 in annual profit, vs $-5 for QNTM. On the Piotroski fundamental quality scale (0–9), NRXP scores 5/9 vs QNTM's 1/9, reflecting solid financial health.
| Metric | QNTMQuantum BioPharma… | SAVACassava Sciences,… | ANVSAnnovis Bio, Inc. | NRXPNRx Pharmaceutica… |
|---|---|---|---|---|
| ROE (TTM)Return on equity | -5.5% | -95.8% | -0.7% | — |
| ROA (TTM)Return on assets | -189.1% | -75.3% | -0.5% | -4.9% |
| ROICReturn on invested capital | -2.3% | -6.3% | — | — |
| ROCEReturn on capital employed | -2.0% | -99.9% | -0.3% | — |
| Piotroski ScoreFundamental quality 0–9 | 1 | 2 | 2 | 5 |
| Debt / EquityFinancial leverage | 0.37x | — | — | — |
| Net DebtTotal debt minus cash | -$29,093 | -$129M | -$19.5B | -$7M |
| Cash & Equiv.Liquid assets | $2M | $129M | $19.5B | $8M |
| Total DebtShort + long-term debt | $2M | $0 | $0 | $631,000 |
| Interest CoverageEBIT ÷ Interest expense | -32.67x | — | — | -24.18x |
ANVS leads this category, winning 5 of 8 comparable metrics.
Total Returns (Dividends Reinvested)
SAVA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in SAVA five years ago would be worth $3,302 today (with dividends reinvested), compared to $92 for NRXP. Over the past 12 months, NRXP leads with a +55.3% total return vs QNTM's -40.4%. The 3-year compound annual growth rate (CAGR) favors SAVA at -16.0% vs QNTM's -60.2% — a key indicator of consistent wealth creation.
| Metric | QNTMQuantum BioPharma… | SAVACassava Sciences,… | ANVSAnnovis Bio, Inc. | NRXPNRx Pharmaceutica… |
|---|---|---|---|---|
| YTD ReturnYear-to-date | -28.5% | -6.5% | -37.8% | +16.8% |
| 1-Year ReturnPast 12 months | -40.4% | +25.3% | +43.7% | +55.3% |
| 3-Year ReturnCumulative with dividends | -93.7% | -40.8% | -84.7% | -50.6% |
| 5-Year ReturnCumulative with dividends | -95.5% | -67.0% | -90.3% | -99.1% |
| 10-Year ReturnCumulative with dividends | -99.6% | -19.5% | -76.3% | -96.8% |
| CAGR (3Y)Annualised 3-year return | -60.2% | -16.0% | -46.5% | -21.0% |
SAVA leads this category, winning 4 of 6 comparable metrics.
Risk & Volatility
Evenly matched — QNTM and NRXP each lead in 1 of 2 comparable metrics.
Risk & Volatility
QNTM is the less volatile stock with a 0.98 beta — it tends to amplify market swings less than ANVS's 2.16 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NRXP currently trades 79.7% from its 52-week high vs QNTM's 13.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | QNTMQuantum BioPharma… | SAVACassava Sciences,… | ANVSAnnovis Bio, Inc. | NRXPNRx Pharmaceutica… |
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.97x | 1.99x | 2.08x | 1.89x |
| 52-Week HighHighest price in past year | $38.25 | $4.98 | $5.50 | $3.84 |
| 52-Week LowLowest price in past year | $2.07 | $1.51 | $1.44 | $1.62 |
| % of 52W HighCurrent price vs 52-week peak | +13.1% | +39.3% | +41.3% | +79.7% |
| RSI (14)Momentum oscillator 0–100 | 62.5 | 46.8 | 63.5 | 64.7 |
| Avg Volume (50D)Average daily shares traded | 495K | 712K | 889K | 913K |
Evenly matched — QNTM and NRXP each lead in 1 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | QNTMQuantum BioPharma… | SAVACassava Sciences,… | ANVSAnnovis Bio, Inc. | NRXPNRx Pharmaceutica… |
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | — | — |
| Price TargetConsensus 12-month target | — | — | — | — |
| # AnalystsCovering analysts | — | 12 | — | — |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 1 | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
QNTM leads in 1 of 6 categories (Income & Cash Flow). ANVS leads in 1 (Profitability & Efficiency). 2 tied.
Best OverallQuantum BioPharma Ltd. (QNTM)Leads 1 of 6 categories
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QNTM vs SAVA vs ANVS vs NRXP: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is QNTM or SAVA or ANVS or NRXP a better buy right now?
Analysts rate Cassava Sciences, Inc.
(SAVA) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — QNTM or SAVA or ANVS or NRXP?
Over the past 5 years, Cassava Sciences, Inc.
(SAVA) delivered a total return of -67. 0%, compared to -99. 1% for NRx Pharmaceuticals, Inc. (NRXP). Over 10 years, the gap is even starker: SAVA returned -19. 5% versus QNTM's -99. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — QNTM or SAVA or ANVS or NRXP?
By beta (market sensitivity over 5 years), Quantum BioPharma Ltd.
(QNTM) is the lower-risk stock at 0. 97β versus Annovis Bio, Inc. 's 2. 08β — meaning ANVS is approximately 115% more volatile than QNTM relative to the S&P 500.
04Which is growing faster — QNTM or SAVA or ANVS or NRXP?
On earnings-per-share growth, the picture is similar: Annovis Bio, Inc.
grew EPS 99. 9% year-over-year, compared to 35. 1% for Quantum BioPharma Ltd.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — QNTM or SAVA or ANVS or NRXP?
Quantum BioPharma Ltd.
(QNTM) is the more profitable company, earning 0. 0% net margin versus -23. 4% for NRx Pharmaceuticals, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: QNTM leads at 0. 0% versus -1324. 4% for NRXP. At the gross margin level — before operating expenses — NRXP leads at 59. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — QNTM or SAVA or ANVS or NRXP?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is QNTM or SAVA or ANVS or NRXP better for a retirement portfolio?
For long-horizon retirement investors, Quantum BioPharma Ltd.
(QNTM) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 97)). Annovis Bio, Inc. (ANVS) carries a higher beta of 2. 08 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (QNTM: -99. 6%, ANVS: -76. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between QNTM and SAVA and ANVS and NRXP?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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