VCP ScannerFree US Stock Screener & Financial AnalysisFree US Stock Screener

Annovis Bio, Inc. (ANVS) Total Return Calculator with Dividends Reinvested

Annovis Bio, Inc.

Popular:

The total return for Annovis Bio, Inc. (ANVS) stock is +66.67% over the past 12 months. So far it's down 34.25% this year. The 5-year total return is -89.05%, meaning $10,000 invested in ANVS stock 5 years ago would be worth $1,095 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in ANVS 1 year ago, it would be worth $15,190 today — you'd have gained $5,190.

With Dividends Reinvested$15,190+51.90%

Price Only (No DRIP)$15,190+51.90%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in ANVS

1Y$16,667+$6,667 (+66.7%)66.7% CAGR

3Y$1,622-$8,378 (-83.8%)-45.5% CAGR

5Y$1,095-$8,905 (-89.1%)-35.7% CAGR

10Y$2,503-$7,497 (-75.0%)-12.9% CAGR

15Y$2,503-$7,497 (-75.0%)-8.8% CAGR

20Y$2,503-$7,497 (-75.0%)-6.7% CAGR

30Y$2,503-$7,497 (-75.0%)-4.5% CAGR

Annovis Bio, Inc. did not pay dividends during this period. Total return = price return.

Loading ANVS total return...

As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-34.25%	—	-34.25%	—	$6,575
1Y	+66.67%	66.67%	+66.67%	—	$16,667
3Y	-83.78%	-45.47%	-83.78%	—	$1,622
5Y	-89.05%	-35.75%	-89.05%	—	$1,095
10Y	-74.97%	-12.94%	-74.97%	—	$2,503
15Y	-74.97%	-8.82%	-74.97%	—	$2,503
20Y	-74.97%	-6.69%	-74.97%	—	$2,503
30Y	-74.97%	-4.51%	-74.97%	—	$2,503

Risk & Highlights

Best Year+115.71%2021

Worst Year-73.43%2024

Max Drawdown-68.82%2025-11-28 → 2026-04-10

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-26.58%	-26.58%	—	+0.41%	-27.0pp
2025	-32.29%	-32.29%	—	+16.64%	-48.9pp
2024	-73.43%	-73.43%	—	+24.00%	-97.4pp
2023	+43.96%	+43.96%	—	+24.81%	+19.1pp
2022	-32.10%	-32.10%	—	-19.95%	-12.2pp

ANVS outperformed the S&P 500 by 35.34pp over the past year (+66.67% vs +31.32%).

Loading summary...

ANVS Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
ANVSAnnovis Bio, Inc.	$65M	+2.1%	-34.2%	+66.7%	—	-83.8%	-89.1%	-75.0%
SAVACassava Sciences, Inc.	$94M	—	-6.5%	+29.5%	—	-40.8%	-67.3%	-18.5%
PRTAProthena Corporation plc	$602M	+11.4%	+21.5%	+52.1%	—	-85.5%	-52.7%	-70.8%
ACADACADIA Pharmaceuticals Inc.	$3.7B	-3.8%	-17.9%	+47.7%	—	-0.3%	+2.5%	-22.3%
AVXLAnavex Life Sciences Corp.	$310M	+12.8%	-9.2%	-59.4%	—	-60.3%	-71.1%	-30.6%
ATHAAthira Pharma, Inc.	$17M	—	-37.6%	+70.2%	—	-84.8%	-97.6%	-97.5%
BIIBBiogen Inc.	$28.2B	+10.6%	+7.2%	+63.2%	—	-39.3%	-29.9%	-27.7%
LLYEli Lilly and Company	$932.6B	+6.5%	-8.5%	+28.2%	+0.8pp	+131.9%	+421.4%	+1271.7%
ALNYAlnylam Pharmaceuticals, Inc.	$40.4B	-8.3%	-24.3%	+12.3%	—	+44.3%	+129.4%	+445.5%
IONSIonis Pharmaceuticals, Inc.	$12.7B	+3.4%	-3.5%	+141.2%	—	+118.4%	+105.9%	+126.0%
CRLCharles River Laboratories International, Inc.	$9.0B	+8.0%	-10.2%	+57.5%	—	-4.3%	-46.0%	+124.7%

Compare:ANVS vs SAVA ANVS vs PRTA ANVS vs ACAD ANVS vs SAVA vs PRTA

About ANVS Dividend Returns

Annovis Bio, Inc. (ANVS) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of ANVS over the past year?

Annovis Bio, Inc. (ANVS) delivered a return of 66.67% over the past year. Since ANVS does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in ANVS be worth today?

A $10,000 investment in Annovis Bio, Inc. one year ago would be worth $16,667 today, representing a gain of $6,667.

Q3Does ANVS pay dividends?

Annovis Bio, Inc. (ANVS) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For ANVS, the total return equals the price-only return.

Q4Did ANVS beat the S&P 500?

Yes, Annovis Bio, Inc. (ANVS) outperformed the S&P 500 by 35.34 percentage points over the past year. ANVS delivered a total return of 66.67%, compared to the S&P 500's 31.32%. This 35.34pp alpha means investors in ANVS earned more than a passive S&P 500 index fund.

Q5What is ANVS's worst drawdown?

Annovis Bio, Inc. (ANVS) experienced a maximum drawdown of -68.82% over the past year, declining from its peak on 2025-11-28 to its trough on 2026-04-10. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is ANVS's long-term total return over 10, 20, or 30 years?

Here are Annovis Bio, Inc. (ANVS)'s long-term returns with dividends reinvested. Over 10 years, the total return is -75.0% (-12.9% CAGR) — $10,000 would have grown to $2,503. Over 20 years: -75.0% total return (-6.7% CAGR) — $10,000 → $2,503. Over 30 years: -75.0% total return (-4.5% CAGR) — $10,000 → $2,503. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was ANVS's best and worst year?

Annovis Bio, Inc.'s best calendar year was 2021 with a total return of 115.7%. Its worst year was 2024 with a total return of -73.4%. This range shows the volatility investors should expect — the difference between the best and worst year is 189.1 percentage points.