Biotechnology
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Side-by-side financial analysisStock Comparison
QTTB vs IMVT vs ARDX vs PRAX vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Medical - Diagnostics & Research
QTTB vs IMVT vs ARDX vs PRAX vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Medical - Diagnostics & Research |
| Market Cap | $161M | $6.90B | $1.40B | $7.70B | $30.79B |
| Revenue (TTM) | $54M | $0.00 | $428M | $0.00 | $16.63B |
| Net Income (TTM) | $33M | $-506M | $-58M | $-327M | $1.39B |
| Gross Margin | 99.5% | — | 91.9% | — | 26.1% |
| Operating Margin | 39.8% | — | -8.7% | — | 13.9% |
| Forward P/E | 5.2x | — | — | — | 14.2x |
| Total Debt | $15M | $72K | $212M | $110K | $16.17B |
| Cash & Equiv. | $48M | $902M | $68M | $357M | $1.98B |
QTTB vs IMVT vs ARDX vs PRAX vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Oct 20 | Jun 26 | Return |
|---|---|---|---|
| Q32 Bio Inc. (QTTB) | 100 | 6.6 | -93.4% |
| Immunovant, Inc. (IMVT) | 100 | 77.1 | -22.9% |
| Ardelyx, Inc. (ARDX) | 100 | 444.5 | +344.5% |
| Praxis Precision Me… (PRAX) | 100 | 50.8 | -49.2% |
| IQVIA Holdings Inc. (IQV) | 100 | 117.8 | +17.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: QTTB vs IMVT vs ARDX vs PRAX vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
QTTB carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- beta 0.50
- Lower volatility, beta 0.50, Low D/E 36.5%, current ratio 4.85x
- Beta 0.50, current ratio 4.85x
- 156.7% revenue growth vs PRAX's -100.0%
IMVT is the #2 pick in this set and the best alternative if long-term compounding is your priority.
- 237.9% 10Y total return vs ARDX's 162.2%
ARDX ranks third and is worth considering specifically for growth exposure.
- Rev growth 22.1%, EPS growth -52.9%, 3Y rev CAGR 98.4%
PRAX lags the leaders in this set but could rank higher in a more targeted comparison.
Among these 5 stocks, IQV doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 156.7% revenue growth vs PRAX's -100.0% | |
| Value | Lower P/E (5.2x vs 14.2x) | |
| Quality / Margins | 61.9% margin vs ARDX's -13.6% | |
| Stability / Safety | Beta 0.50 vs IMVT's 1.66 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +6.4% vs IQV's +14.0% | |
| Efficiency (ROA) | 53.3% ROA vs IMVT's -62.2% |
QTTB vs IMVT vs ARDX vs PRAX vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
QTTB vs IMVT vs ARDX vs PRAX vs IQV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
QTTB leads in 3 of 6 categories
IMVT leads 0 • ARDX leads 0 • PRAX leads 0 • IQV leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
QTTB leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IQV and PRAX operate at a comparable scale, with $16.6B and $0 in trailing revenue. QTTB is the more profitable business, keeping 61.9% of every revenue dollar as net income compared to ARDX's -13.6%. On growth, ARDX holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $54M | $0 | $428M | $0 | $16.6B |
| EBITDAEarnings before interest/tax | $22M | -$532M | -$35M | -$357M | $3.5B |
| Net IncomeAfter-tax profit | $33M | -$506M | -$58M | -$327M | $1.4B |
| Free Cash FlowCash after capex | -$27M | -$407M | -$37M | -$283M | $2.7B |
| Gross MarginGross profit ÷ Revenue | +99.5% | — | +91.9% | — | +26.1% |
| Operating MarginEBIT ÷ Revenue | +39.8% | — | -8.7% | — | +13.9% |
| Net MarginNet income ÷ Revenue | +61.9% | — | -13.6% | — | +8.3% |
| FCF MarginFCF ÷ Revenue | -51.0% | — | -8.8% | — | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +27.5% | — | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +40.0% | -14.1% | +11.8% | +2.7% | +15.0% |
Valuation Metrics
QTTB leads this category, winning 2 of 4 comparable metrics.
Valuation Metrics
At 5.2x trailing earnings, QTTB trades at a 77% valuation discount to IQV's 23.1x P/E. On an enterprise value basis, QTTB's 7.4x EV/EBITDA is more attractive than IQV's 13.1x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $161M | $6.9B | $1.4B | $7.7B | $30.8B |
| Enterprise ValueMkt cap + debt − cash | $129M | $6.0B | $1.5B | $7.3B | $45.0B |
| Trailing P/EPrice ÷ TTM EPS | 5.22x | -12.14x | -21.88x | -19.77x | 23.15x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 14.16x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 0.57x |
| EV / EBITDAEnterprise value multiple | 7.43x | — | — | — | 13.11x |
| Price / SalesMarket cap ÷ Revenue | 3.01x | — | 3.43x | — | 1.89x |
| Price / BookPrice ÷ Book value/share | 3.70x | 7.19x | 8.21x | 6.83x | 4.75x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | 15.01x |
Profitability & Efficiency
QTTB leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
QTTB delivers a 2.3% return on equity — every $100 of shareholder capital generates $2 in annual profit, vs $-68 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), QTTB scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +2.3% | -68.2% | -38.1% | -43.0% | +22.1% |
| ROA (TTM)Return on assets | +53.3% | -62.2% | -11.8% | -40.2% | +4.7% |
| ROICReturn on invested capital | — | — | -10.7% | -65.0% | +8.7% |
| ROCEReturn on capital employed | +26.8% | -68.3% | -10.6% | -49.3% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 2 | 3 | 3 | 4 |
| Debt / EquityFinancial leverage | 0.37x | 0.00x | 1.27x | 0.00x | 2.44x |
| Net DebtTotal debt minus cash | -$33M | -$902M | $144M | -$357M | $14.2B |
| Cash & Equiv.Liquid assets | $48M | $902M | $68M | $357M | $2.0B |
| Total DebtShort + long-term debt | $15M | $72,000 | $212M | $110,000 | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | 21.88x | — | -0.28x | — | 3.10x |
Total Returns (Dividends Reinvested)
Evenly matched — QTTB and IMVT and PRAX each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $950 for QTTB. Over the past 12 months, QTTB leads with a +643.5% total return vs IQV's +14.0%. The 3-year compound annual growth rate (CAGR) favors PRAX at 164.8% vs QTTB's -14.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +267.4% | +29.8% | -7.5% | -6.9% | -19.5% |
| 1-Year ReturnPast 12 months | +643.5% | +110.9% | +53.0% | +491.9% | +14.0% |
| 3-Year ReturnCumulative with dividends | -37.3% | +55.0% | +42.6% | +1757.4% | -14.4% |
| 5-Year ReturnCumulative with dividends | -90.5% | +213.0% | +207.6% | -14.2% | -25.8% |
| 10-Year ReturnCumulative with dividends | -96.2% | +237.9% | +162.2% | -36.1% | +177.5% |
| CAGR (3Y)Annualised 3-year return | -14.4% | +15.7% | +12.6% | +164.8% | -5.0% |
Risk & Volatility
Evenly matched — QTTB and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
QTTB is the less volatile stock with a 0.50 beta — it tends to amplify market swings less than IMVT's 1.66 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 92.7% from its 52-week high vs ARDX's 67.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.50x | 1.66x | 1.01x | 1.55x | 1.16x |
| 52-Week HighHighest price in past year | $14.85 | $36.27 | $8.40 | $366.52 | $247.05 |
| 52-Week LowLowest price in past year | $1.35 | $14.32 | $3.49 | $37.19 | $153.01 |
| % of 52W HighCurrent price vs 52-week peak | +85.1% | +92.7% | +67.7% | +72.7% | +73.5% |
| RSI (14)Momentum oscillator 0–100 | 64.2 | 57.9 | 45.0 | 31.9 | 54.4 |
| Avg Volume (50D)Average daily shares traded | 827K | 1.9M | 3.4M | 396K | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: QTTB as "Hold", IMVT as "Buy", ARDX as "Buy", PRAX as "Buy", IQV as "Buy". Consensus price targets imply 198.8% upside for ARDX (target: $17) vs 6.8% for QTTB (target: $14).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $13.50 | $43.67 | $17.00 | $607.15 | $222.22 |
| # AnalystsCovering analysts | 8 | 23 | 16 | 16 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | 2 |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | +4.0% |
QTTB leads in 3 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 2 categories are tied.
QTTB vs IMVT vs ARDX vs PRAX vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is QTTB or IMVT or ARDX or PRAX or IQV a better buy right now?
For growth investors, Ardelyx, Inc.
(ARDX) is the stronger pick with 22. 1% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). Q32 Bio Inc. (QTTB) offers the better valuation at 5. 2x trailing P/E, making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — QTTB or IMVT or ARDX or PRAX or IQV?
On trailing P/E, Q32 Bio Inc.
(QTTB) is the cheapest at 5. 2x versus IQVIA Holdings Inc. at 23. 1x.
03Which is the better long-term investment — QTTB or IMVT or ARDX or PRAX or IQV?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +213. 0%, compared to -90. 5% for Q32 Bio Inc. (QTTB). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus QTTB's -96. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — QTTB or IMVT or ARDX or PRAX or IQV?
By beta (market sensitivity over 5 years), Q32 Bio Inc.
(QTTB) is the lower-risk stock at 0. 50β versus Immunovant, Inc. 's 1. 66β — meaning IMVT is approximately 231% more volatile than QTTB relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — QTTB or IMVT or ARDX or PRAX or IQV?
By revenue growth (latest reported year), Ardelyx, Inc.
(ARDX) is pulling ahead at 22. 1% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: Q32 Bio Inc. grew EPS 136. 8% year-over-year, compared to -52. 9% for Ardelyx, Inc.. Over a 3-year CAGR, QTTB leads at 100. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — QTTB or IMVT or ARDX or PRAX or IQV?
Q32 Bio Inc.
(QTTB) is the more profitable company, earning 55. 5% net margin versus -15. 1% for Ardelyx, Inc. — meaning it keeps 55. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: QTTB leads at 31. 5% versus -10. 1% for ARDX. At the gross margin level — before operating expenses — QTTB leads at 99. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is QTTB or IMVT or ARDX or PRAX or IQV more undervalued right now?
Analyst consensus price targets imply the most upside for ARDX: 198.
8% to $17. 00.
08Which pays a better dividend — QTTB or IMVT or ARDX or PRAX or IQV?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is QTTB or IMVT or ARDX or PRAX or IQV better for a retirement portfolio?
For long-horizon retirement investors, Q32 Bio Inc.
(QTTB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 50)). Praxis Precision Medicines, Inc. (PRAX) carries a higher beta of 1. 55 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (QTTB: -96. 2%, PRAX: -36. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between QTTB and IMVT and ARDX and PRAX and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: QTTB is a small-cap deep-value stock; IMVT is a small-cap quality compounder stock; ARDX is a small-cap high-growth stock; PRAX is a small-cap quality compounder stock; IQV is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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