Drug Manufacturers - Specialty & Generic
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5 / 10Stock Comparison
RDHL vs DBVT vs REGN vs IQV vs CRL
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Diagnostics & Research
Medical - Diagnostics & Research
RDHL vs DBVT vs REGN vs IQV vs CRL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology | Medical - Diagnostics & Research | Medical - Diagnostics & Research |
| Market Cap | $5M | $1690.08T | $74.28B | $30.33B | $8.76B |
| Revenue (TTM) | $10M | $0.00 | $14.92B | $16.63B | $4.03B |
| Net Income (TTM) | $-9M | $-168M | $4.42B | $1.39B | $-185M |
| Gross Margin | 64.5% | — | 84.5% | 26.1% | 31.9% |
| Operating Margin | -110.4% | — | 24.3% | 13.9% | 11.8% |
| Forward P/E | — | — | 15.5x | 14.0x | 16.0x |
| Total Debt | $356K | $22M | $2.71B | $16.17B | $3.07B |
| Cash & Equiv. | $5M | $194M | $3.12B | $1.98B | $214M |
RDHL vs DBVT vs REGN vs IQV vs CRL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| RedHill Biopharma L… (RDHL) | 100 | 0.0 | -100.0% |
| DBV Technologies S.… (DBVT) | 100 | 40.7 | -59.3% |
| Regeneron Pharmaceu… (REGN) | 100 | 116.7 | +16.7% |
| IQVIA Holdings Inc. (IQV) | 100 | 119.5 | +19.5% |
| Charles River Labor… (CRL) | 100 | 98.9 | -1.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: RDHL vs DBVT vs REGN vs IQV vs CRL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
RDHL is the #2 pick in this set and the best alternative if growth is your priority.
- 23.2% revenue growth vs DBVT's -100.0%
DBVT ranks third and is worth considering specifically for momentum.
- +100.5% vs RDHL's -49.0%
REGN carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 1 yrs, beta 0.77, yield 0.5%
- Rev growth 1.0%, EPS growth 8.2%, 3Y rev CAGR 5.6%
- Lower volatility, beta 0.77, Low D/E 8.7%, current ratio 4.13x
- Beta 0.77, yield 0.5%, current ratio 4.13x
IQV is the clearest fit if your priority is long-term compounding and valuation efficiency.
- 166.6% 10Y total return vs REGN's 91.6%
- PEG 0.34 vs REGN's 2.44
- Lower P/E (14.0x vs 16.0x)
Among these 5 stocks, CRL doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 23.2% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (14.0x vs 16.0x) | |
| Quality / Margins | 29.6% margin vs RDHL's -97.5% | |
| Stability / Safety | Beta 0.77 vs CRL's 1.44, lower leverage | |
| Dividends | 0.5% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +100.5% vs RDHL's -49.0% | |
| Efficiency (ROA) | 11.1% ROA vs DBVT's -89.0% |
RDHL vs DBVT vs REGN vs IQV vs CRL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
RDHL vs DBVT vs REGN vs IQV vs CRL — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
REGN leads in 3 of 6 categories
IQV leads 2 • DBVT leads 1 • RDHL leads 0 • CRL leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
REGN leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IQV and DBVT operate at a comparable scale, with $16.6B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to RDHL's -97.5%. On growth, RDHL holds the edge at +58.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $10M | $0 | $14.9B | $16.6B | $4.0B |
| EBITDAEarnings before interest/tax | -$10M | -$112M | $4.2B | $3.5B | $824M |
| Net IncomeAfter-tax profit | -$9M | -$168M | $4.4B | $1.4B | -$185M |
| Free Cash FlowCash after capex | -$8M | -$151M | $4.2B | $2.7B | $391M |
| Gross MarginGross profit ÷ Revenue | +64.5% | — | +84.5% | +26.1% | +31.9% |
| Operating MarginEBIT ÷ Revenue | -110.4% | — | +24.3% | +13.9% | +11.8% |
| Net MarginNet income ÷ Revenue | -97.5% | — | +29.6% | +8.3% | -4.6% |
| FCF MarginFCF ÷ Revenue | -86.0% | — | +27.9% | +16.1% | +9.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | +58.6% | — | +19.0% | +8.4% | +1.2% |
| EPS Growth (YoY)Latest quarter vs prior year | 0.0% | +91.5% | -7.2% | +15.0% | -160.0% |
Valuation Metrics
IQV leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 17.2x trailing earnings, REGN trades at a 24% valuation discount to IQV's 22.8x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs REGN's 2.72x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $5M | $1690.08T | $74.3B | $30.3B | $8.8B |
| Enterprise ValueMkt cap + debt − cash | $903,014 | $1690.08T | $73.9B | $44.5B | $11.6B |
| Trailing P/EPrice ÷ TTM EPS | -0.14x | -0.75x | 17.23x | 22.79x | -61.04x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 15.46x | 13.96x | 16.00x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.72x | 0.56x | — |
| EV / EBITDAEnterprise value multiple | — | — | 17.92x | 12.98x | 12.75x |
| Price / SalesMarket cap ÷ Revenue | 0.64x | — | 5.18x | 1.86x | 2.18x |
| Price / BookPrice ÷ Book value/share | — | 0.65x | 2.48x | 4.68x | 2.74x |
| Price / FCFMarket cap ÷ FCF | — | — | 18.20x | 14.79x | 16.90x |
Profitability & Efficiency
REGN leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
IQV delivers a 22.1% return on equity — every $100 of shareholder capital generates $22 in annual profit, vs $-130 for DBVT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), REGN scores 5/9 vs RDHL's 3/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -130.2% | +14.3% | +22.1% | -5.7% |
| ROA (TTM)Return on assets | -51.1% | -89.0% | +11.1% | +4.7% | -2.5% |
| ROICReturn on invested capital | — | — | +8.9% | +8.7% | +6.3% |
| ROCEReturn on capital employed | — | -145.7% | +10.2% | +11.0% | +8.1% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 5 | 4 | 4 |
| Debt / EquityFinancial leverage | — | 0.13x | 0.09x | 2.44x | 0.95x |
| Net DebtTotal debt minus cash | -$4M | -$172M | -$412M | $14.2B | $2.9B |
| Cash & Equiv.Liquid assets | $5M | $194M | $3.1B | $2.0B | $214M |
| Total DebtShort + long-term debt | $356,000 | $22M | $2.7B | $16.2B | $3.1B |
| Interest CoverageEBIT ÷ Interest expense | -7.99x | -189.82x | 108.44x | 3.10x | 4.29x |
Total Returns (Dividends Reinvested)
DBVT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in REGN five years ago would be worth $14,320 today (with dividends reinvested), compared to $2 for RDHL. Over the past 12 months, DBVT leads with a +100.5% total return vs RDHL's -49.0%. The 3-year compound annual growth rate (CAGR) favors DBVT at 5.7% vs RDHL's -74.3% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -1.9% | +3.6% | -7.8% | -20.7% | -12.3% |
| 1-Year ReturnPast 12 months | -49.0% | +100.5% | +31.2% | +16.6% | +25.7% |
| 3-Year ReturnCumulative with dividends | -98.3% | +18.1% | -4.4% | -5.9% | -6.5% |
| 5-Year ReturnCumulative with dividends | -100.0% | -68.3% | +43.2% | -22.8% | -46.6% |
| 10-Year ReturnCumulative with dividends | -100.0% | -87.1% | +91.6% | +166.6% | +114.0% |
| CAGR (3Y)Annualised 3-year return | -74.3% | +5.7% | -1.5% | -2.0% | -2.2% |
Risk & Volatility
REGN leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
REGN is the less volatile stock with a 0.77 beta — it tends to amplify market swings less than CRL's 1.44 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 87.1% from its 52-week high vs RDHL's 30.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.30x | 1.26x | 0.77x | 1.32x | 1.44x |
| 52-Week HighHighest price in past year | $3.31 | $26.18 | $821.11 | $247.05 | $228.88 |
| 52-Week LowLowest price in past year | $0.71 | $7.53 | $476.49 | $134.65 | $132.58 |
| % of 52W HighCurrent price vs 52-week peak | +30.5% | +75.3% | +87.1% | +72.3% | +77.6% |
| RSI (14)Momentum oscillator 0–100 | 60.1 | 47.4 | 41.7 | 60.3 | 57.4 |
| Avg Volume (50D)Average daily shares traded | 39K | 252K | 626K | 1.5M | 792K |
Analyst Outlook
IQV leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", REGN as "Buy", IQV as "Buy", CRL as "Buy". Consensus price targets imply 134.8% upside for DBVT (target: $46) vs 16.2% for CRL (target: $206). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $46.33 | $865.68 | $223.75 | $206.43 |
| # AnalystsCovering analysts | — | 15 | 48 | 44 | 36 |
| Dividend YieldAnnual dividend ÷ price | — | — | +0.5% | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | 1 | 2 | 1 |
| Dividend / ShareAnnual DPS | — | — | $3.41 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +5.3% | +4.1% | +4.1% |
REGN leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IQV leads in 2 (Valuation Metrics, Analyst Outlook).
RDHL vs DBVT vs REGN vs IQV vs CRL: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is RDHL or DBVT or REGN or IQV or CRL a better buy right now?
For growth investors, RedHill Biopharma Ltd.
(RDHL) is the stronger pick with 23. 2% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 2x trailing P/E (15. 5x forward), making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — RDHL or DBVT or REGN or IQV or CRL?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 2x versus IQVIA Holdings Inc. at 22. 8x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 14. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 44x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — RDHL or DBVT or REGN or IQV or CRL?
Over the past 5 years, Regeneron Pharmaceuticals, Inc.
(REGN) delivered a total return of +43. 2%, compared to -100. 0% for RedHill Biopharma Ltd. (RDHL). Over 10 years, the gap is even starker: IQV returned +166. 6% versus RDHL's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — RDHL or DBVT or REGN or IQV or CRL?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.
(REGN) is the lower-risk stock at 0. 77β versus Charles River Laboratories International, Inc. 's 1. 44β — meaning CRL is approximately 88% more volatile than REGN relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — RDHL or DBVT or REGN or IQV or CRL?
By revenue growth (latest reported year), RedHill Biopharma Ltd.
(RDHL) is pulling ahead at 23. 2% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — RDHL or DBVT or REGN or IQV or CRL?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -102. 8% for RedHill Biopharma Ltd. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus -181. 7% for RDHL. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is RDHL or DBVT or REGN or IQV or CRL more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 44x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, IQVIA Holdings Inc. (IQV) trades at 14. 0x forward P/E versus 16. 0x for Charles River Laboratories International, Inc. — 2. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 134. 8% to $46. 33.
08Which pays a better dividend — RDHL or DBVT or REGN or IQV or CRL?
In this comparison, REGN (0.
5% yield) pays a dividend. RDHL, DBVT, IQV, CRL do not pay a meaningful dividend and should not be held primarily for income.
09Is RDHL or DBVT or REGN or IQV or CRL better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.
(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 77)). Both have compounded well over 10 years (REGN: +91. 6%, RDHL: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between RDHL and DBVT and REGN and IQV and CRL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: RDHL is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; REGN is a mid-cap deep-value stock; IQV is a mid-cap quality compounder stock; CRL is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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