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REGN vs LLY
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
REGN vs LLY — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General |
| Market Cap | $74.89B | $932.64B |
| Revenue (TTM) | $14.92B | $72.25B |
| Net Income (TTM) | $4.42B | $25.27B |
| Gross Margin | 84.5% | 83.5% |
| Operating Margin | 24.3% | 45.9% |
| Forward P/E | 15.6x | 28.6x |
| Total Debt | $2.71B | $42.50B |
| Cash & Equiv. | $3.12B | $7.16B |
REGN vs LLY — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Regeneron Pharmaceu… (REGN) | 100 | 117.6 | +17.6% |
| Eli Lilly and Compa… (LLY) | 100 | 645.4 | +545.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: REGN vs LLY
Each card shows where this stock fits in a portfolio — not just who wins on paper.
REGN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
- Lower P/E (15.6x vs 28.6x)
- +29.7% vs LLY's +28.2%
LLY carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 11 yrs, beta 0.71, yield 0.6%
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 12.7% 10Y total return vs REGN's 96.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 44.7% revenue growth vs REGN's 1.0% | |
| Value | Lower P/E (15.6x vs 28.6x) | |
| Quality / Margins | 35.0% margin vs REGN's 29.6% | |
| Stability / Safety | Beta 0.71 vs REGN's 0.81 | |
| Dividends | 0.6% yield, 11-year raise streak, vs REGN's 0.5% | |
| Momentum (1Y) | +29.7% vs LLY's +28.2% | |
| Efficiency (ROA) | 22.7% ROA vs REGN's 11.1%, ROIC 41.8% vs 8.9% |
REGN vs LLY — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
REGN vs LLY — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
LLY is the larger business by revenue, generating $72.2B annually — 4.8x REGN's $14.9B. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to REGN's 29.6%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $14.9B | $72.2B |
| EBITDAEarnings before interest/tax | $4.2B | $34.7B |
| Net IncomeAfter-tax profit | $4.4B | $25.3B |
| Free Cash FlowCash after capex | $4.2B | $13.6B |
| Gross MarginGross profit ÷ Revenue | +84.5% | +83.5% |
| Operating MarginEBIT ÷ Revenue | +24.3% | +45.9% |
| Net MarginNet income ÷ Revenue | +29.6% | +35.0% |
| FCF MarginFCF ÷ Revenue | +27.9% | +18.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | +19.0% | +55.5% |
| EPS Growth (YoY)Latest quarter vs prior year | -7.2% | +169.9% |
Valuation Metrics
REGN leads this category, winning 6 of 7 comparable metrics.
Valuation Metrics
At 17.4x trailing earnings, REGN trades at a 60% valuation discount to LLY's 43.0x P/E. Adjusting for growth (PEG ratio), LLY offers better value at 1.49x vs REGN's 2.75x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||
|---|---|---|
| Market CapShares × price | $74.9B | $932.6B |
| Enterprise ValueMkt cap + debt − cash | $74.5B | $968.0B |
| Trailing P/EPrice ÷ TTM EPS | 17.38x | 43.01x |
| Forward P/EPrice ÷ next-FY EPS est. | 15.60x | 28.59x |
| PEG RatioP/E ÷ EPS growth rate | 2.75x | 1.49x |
| EV / EBITDAEnterprise value multiple | 18.07x | 30.97x |
| Price / SalesMarket cap ÷ Revenue | 5.22x | 14.31x |
| Price / BookPrice ÷ Book value/share | 2.50x | 33.41x |
| Price / FCFMarket cap ÷ FCF | 18.35x | 103.95x |
Profitability & Efficiency
LLY leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $14 for REGN. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to LLY's 1.60x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs REGN's 5/9, reflecting strong financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | +14.3% | +101.2% |
| ROA (TTM)Return on assets | +11.1% | +22.7% |
| ROICReturn on invested capital | +8.9% | +41.8% |
| ROCEReturn on capital employed | +10.2% | +46.6% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 8 |
| Debt / EquityFinancial leverage | 0.09x | 1.60x |
| Net DebtTotal debt minus cash | -$412M | $35.3B |
| Cash & Equiv.Liquid assets | $3.1B | $7.2B |
| Total DebtShort + long-term debt | $2.7B | $42.5B |
| Interest CoverageEBIT ÷ Interest expense | 108.44x | 35.68x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $52,144 today (with dividends reinvested), compared to $14,543 for REGN. Over the past 12 months, REGN leads with a +29.7% total return vs LLY's +28.2%. The 3-year compound annual growth rate (CAGR) favors LLY at 32.4% vs REGN's -1.2% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -7.0% | -8.5% |
| 1-Year ReturnPast 12 months | +29.7% | +28.2% |
| 3-Year ReturnCumulative with dividends | -3.6% | +131.9% |
| 5-Year ReturnCumulative with dividends | +45.4% | +421.4% |
| 10-Year ReturnCumulative with dividends | +96.0% | +1271.7% |
| CAGR (3Y)Annualised 3-year return | -1.2% | +32.4% |
Risk & Volatility
Evenly matched — REGN and LLY each lead in 1 of 2 comparable metrics.
Risk & Volatility
LLY is the less volatile stock with a 0.71 beta — it tends to amplify market swings less than REGN's 0.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.81x | 0.71x |
| 52-Week HighHighest price in past year | $821.11 | $1133.95 |
| 52-Week LowLowest price in past year | $476.49 | $623.78 |
| % of 52W HighCurrent price vs 52-week peak | +87.8% | +87.1% |
| RSI (14)Momentum oscillator 0–100 | 37.9 | 61.6 |
| Avg Volume (50D)Average daily shares traded | 634K | 2.6M |
Analyst Outlook
LLY leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Wall Street rates REGN as "Buy" and LLY as "Buy". Consensus price targets imply 27.5% upside for LLY (target: $1258) vs 20.1% for REGN (target: $866). For income investors, LLY offers the higher dividend yield at 0.61% vs REGN's 0.47%.
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $865.68 | $1258.47 |
| # AnalystsCovering analysts | 48 | 45 |
| Dividend YieldAnnual dividend ÷ price | +0.5% | +0.6% |
| Dividend StreakConsecutive years of raises | 1 | 11 |
| Dividend / ShareAnnual DPS | $3.41 | $6.00 |
| Buyback YieldShare repurchases ÷ mkt cap | +5.3% | +0.4% |
LLY leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). REGN leads in 1 (Valuation Metrics). 1 tied.
REGN vs LLY: Frequently Asked Questions
10 questions · data-driven answers · updated daily
01Is REGN or LLY a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 4x trailing P/E (15. 6x forward), making it the more compelling value choice. Analysts rate Regeneron Pharmaceuticals, Inc. (REGN) a "Buy" — based on 48 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — REGN or LLY?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 4x versus Eli Lilly and Company at 43. 0x. On forward P/E, Regeneron Pharmaceuticals, Inc. is actually cheaper at 15. 6x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Eli Lilly and Company wins at 0. 99x versus Regeneron Pharmaceuticals, Inc. 's 2. 47x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — REGN or LLY?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +421.
4%, compared to +45. 4% for Regeneron Pharmaceuticals, Inc. (REGN). Over 10 years, the gap is even starker: LLY returned +1272% versus REGN's +96. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — REGN or LLY?
By beta (market sensitivity over 5 years), Eli Lilly and Company (LLY) is the lower-risk stock at 0.
71β versus Regeneron Pharmaceuticals, Inc. 's 0. 81β — meaning REGN is approximately 14% more volatile than LLY relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 160% for Eli Lilly and Company — giving it more financial flexibility in a downturn.
05Which is growing faster — REGN or LLY?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to 8. 2% for Regeneron Pharmaceuticals, Inc.. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — REGN or LLY?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus 31. 4% for Regeneron Pharmaceuticals, Inc. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus 24. 9% for REGN. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is REGN or LLY more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Eli Lilly and Company (LLY) is the more undervalued stock at a PEG of 0. 99x versus Regeneron Pharmaceuticals, Inc. 's 2. 47x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Regeneron Pharmaceuticals, Inc. (REGN) trades at 15. 6x forward P/E versus 28. 6x for Eli Lilly and Company — 13. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for LLY: 27. 5% to $1258. 47.
08Which pays a better dividend — REGN or LLY?
All stocks in this comparison pay dividends.
Eli Lilly and Company (LLY) offers the highest yield at 0. 6%, versus 0. 5% for Regeneron Pharmaceuticals, Inc. (REGN).
09Is REGN or LLY better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
71), 0. 6% yield, +1272% 10Y return). Both have compounded well over 10 years (LLY: +1272%, REGN: +96. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between REGN and LLY?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: REGN is a mid-cap deep-value stock; LLY is a large-cap high-growth stock. LLY pays a dividend while REGN does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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