Biotechnology
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REVB vs HALO vs ALNY vs ADMA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
REVB vs HALO vs ALNY vs ADMA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $3M | $7.68B | $39.48B | $2.03B |
| Revenue (TTM) | $0.00 | $1.40B | $4.29B | $510M |
| Net Income (TTM) | $-16M | $317M | $577M | $165M |
| Gross Margin | — | 81.9% | 80.9% | 61.3% |
| Operating Margin | — | 58.4% | 17.5% | 42.1% |
| Forward P/E | — | 8.1x | 44.2x | 8.9x |
| Total Debt | $747K | $0.00 | $1.28B | $80M |
| Cash & Equiv. | $11M | $134M | $1.66B | $88M |
REVB vs HALO vs ALNY vs ADMA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Nov 20 | May 26 | Return |
|---|---|---|---|
| Revelation Bioscien… (REVB) | 100 | 0.0 | -100.0% |
| Halozyme Therapeuti… (HALO) | 100 | 166.7 | +66.7% |
| Alnylam Pharmaceuti… (ALNY) | 100 | 227.8 | +127.8% |
| ADMA Biologics, Inc. (ADMA) | 100 | 415.2 | +315.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: REVB vs HALO vs ALNY vs ADMA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
REVB lags the leaders in this set but could rank higher in a more targeted comparison.
HALO has the current edge in this matchup, primarily because of its strength in income & stability and long-term compounding.
- beta 0.56
- 5.7% 10Y total return vs ALNY's 411.9%
- Beta 0.56, current ratio 4.66x
- Lower P/E (8.1x vs 8.9x)
ALNY is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 65.2%, EPS growth 206.9%, 3Y rev CAGR 53.0%
- 65.2% revenue growth vs REVB's -100.0%
- +7.0% vs REVB's -97.1%
ADMA is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.22, Low D/E 16.7%, current ratio 6.71x
- 32.4% margin vs ALNY's 13.5%
- 27.4% ROA vs REVB's -138.6%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 65.2% revenue growth vs REVB's -100.0% | |
| Value | Lower P/E (8.1x vs 8.9x) | |
| Quality / Margins | 32.4% margin vs ALNY's 13.5% | |
| Stability / Safety | Beta 0.56 vs REVB's 1.36 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +7.0% vs REVB's -97.1% | |
| Efficiency (ROA) | 27.4% ROA vs REVB's -138.6% |
REVB vs HALO vs ALNY vs ADMA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
REVB vs HALO vs ALNY vs ADMA — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 3 of 6 categories
ADMA leads 1 • REVB leads 0 • ALNY leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
HALO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ALNY and REVB operate at a comparable scale, with $4.3B and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to ALNY's 13.5%. On growth, ALNY holds the edge at +96.4% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $1.4B | $4.3B | $510M |
| EBITDAEarnings before interest/tax | -$10M | $945M | $677M | $221M |
| Net IncomeAfter-tax profit | -$16M | $317M | $577M | $165M |
| Free Cash FlowCash after capex | -$9M | $645M | $641M | $108M |
| Gross MarginGross profit ÷ Revenue | — | +81.9% | +80.9% | +61.3% |
| Operating MarginEBIT ÷ Revenue | — | +58.4% | +17.5% | +42.1% |
| Net MarginNet income ÷ Revenue | — | +22.7% | +13.5% | +32.4% |
| FCF MarginFCF ÷ Revenue | — | +46.2% | +15.0% | +21.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +51.6% | +96.4% | -0.3% |
| EPS Growth (YoY)Latest quarter vs prior year | -28.4% | -2.1% | +4.4% | +72.7% |
Valuation Metrics
HALO leads this category, winning 3 of 6 comparable metrics.
Valuation Metrics
At 14.1x trailing earnings, ADMA trades at a 89% valuation discount to ALNY's 127.0x P/E. On an enterprise value basis, HALO's 8.3x EV/EBITDA is more attractive than ALNY's 70.2x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $3M | $7.7B | $39.5B | $2.0B |
| Enterprise ValueMkt cap + debt − cash | -$7M | $7.5B | $39.1B | $2.0B |
| Trailing P/EPrice ÷ TTM EPS | -0.04x | 25.46x | 127.00x | 14.12x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 8.09x | 44.18x | 8.88x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.11x | — | — |
| EV / EBITDAEnterprise value multiple | — | 8.34x | 70.17x | 10.15x |
| Price / SalesMarket cap ÷ Revenue | — | 5.50x | 10.63x | 3.98x |
| Price / BookPrice ÷ Book value/share | 0.07x | 165.47x | 50.50x | 4.35x |
| Price / FCFMarket cap ÷ FCF | — | 11.91x | 84.84x | 73.05x |
Profitability & Efficiency
Evenly matched — HALO and ADMA each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-170 for REVB. REVB carries lower financial leverage with a 0.08x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALNY's 1.62x. On the Piotroski fundamental quality scale (0–9), ALNY scores 6/9 vs REVB's 4/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -169.6% | +6.5% | +98.3% | +39.0% |
| ROA (TTM)Return on assets | -138.6% | +12.5% | +11.8% | +27.4% |
| ROICReturn on invested capital | — | +73.4% | +33.4% | +36.0% |
| ROCEReturn on capital employed | -126.9% | +38.2% | +15.3% | +38.8% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 5 | 6 | 5 |
| Debt / EquityFinancial leverage | 0.08x | — | 1.62x | 0.17x |
| Net DebtTotal debt minus cash | -$10M | -$134M | -$379M | -$8M |
| Cash & Equiv.Liquid assets | $11M | $134M | $1.7B | $88M |
| Total DebtShort + long-term debt | $746,784 | $0 | $1.3B | $80M |
| Interest CoverageEBIT ÷ Interest expense | — | 46.08x | 2.02x | 50.85x |
Total Returns (Dividends Reinvested)
ADMA leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADMA five years ago would be worth $48,678 today (with dividends reinvested), compared to $0 for REVB. Over the past 12 months, ALNY leads with a +7.0% total return vs REVB's -97.1%. The 3-year compound annual growth rate (CAGR) favors ADMA at 34.3% vs REVB's -94.7% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -68.6% | -7.3% | -26.1% | -52.6% |
| 1-Year ReturnPast 12 months | -97.1% | -7.1% | +7.0% | -64.1% |
| 3-Year ReturnCumulative with dividends | -100.0% | +115.3% | +40.9% | +142.0% |
| 5-Year ReturnCumulative with dividends | -100.0% | +37.0% | +125.4% | +386.8% |
| 10-Year ReturnCumulative with dividends | -100.0% | +570.7% | +411.9% | +39.8% |
| CAGR (3Y)Annualised 3-year return | -94.7% | +29.1% | +12.1% | +34.3% |
Risk & Volatility
HALO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
HALO is the less volatile stock with a 0.56 beta — it tends to amplify market swings less than REVB's 1.36 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HALO currently trades 79.3% from its 52-week high vs REVB's 2.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.36x | 0.56x | 0.71x | 1.22x |
| 52-Week HighHighest price in past year | $40.08 | $82.22 | $495.55 | $23.98 |
| 52-Week LowLowest price in past year | $0.60 | $47.50 | $245.96 | $7.21 |
| % of 52W HighCurrent price vs 52-week peak | +2.5% | +79.3% | +59.7% | +35.3% |
| RSI (14)Momentum oscillator 0–100 | 29.7 | 52.4 | 43.8 | 37.9 |
| Avg Volume (50D)Average daily shares traded | 76K | 1.4M | 1.1M | 7.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: HALO as "Buy", ALNY as "Buy", ADMA as "Buy". Consensus price targets imply 165.6% upside for ADMA (target: $23) vs 20.2% for HALO (target: $78).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $78.33 | $445.67 | $22.50 |
| # AnalystsCovering analysts | — | 27 | 52 | 9 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +4.5% | 0.0% | +1.6% |
HALO leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ADMA leads in 1 (Total Returns). 1 tied.
REVB vs HALO vs ALNY vs ADMA: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is REVB or HALO or ALNY or ADMA a better buy right now?
For growth investors, Alnylam Pharmaceuticals, Inc.
(ALNY) is the stronger pick with 65. 2% revenue growth year-over-year, versus 19. 6% for ADMA Biologics, Inc. (ADMA). ADMA Biologics, Inc. (ADMA) offers the better valuation at 14. 1x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate Halozyme Therapeutics, Inc. (HALO) a "Buy" — based on 27 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — REVB or HALO or ALNY or ADMA?
On trailing P/E, ADMA Biologics, Inc.
(ADMA) is the cheapest at 14. 1x versus Alnylam Pharmaceuticals, Inc. at 127. 0x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 1x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — REVB or HALO or ALNY or ADMA?
Over the past 5 years, ADMA Biologics, Inc.
(ADMA) delivered a total return of +386. 8%, compared to -100. 0% for Revelation Biosciences, Inc. (REVB). Over 10 years, the gap is even starker: HALO returned +570. 7% versus REVB's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — REVB or HALO or ALNY or ADMA?
By beta (market sensitivity over 5 years), Halozyme Therapeutics, Inc.
(HALO) is the lower-risk stock at 0. 56β versus Revelation Biosciences, Inc. 's 1. 36β — meaning REVB is approximately 144% more volatile than HALO relative to the S&P 500. On balance sheet safety, Revelation Biosciences, Inc. (REVB) carries a lower debt/equity ratio of 8% versus 162% for Alnylam Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — REVB or HALO or ALNY or ADMA?
By revenue growth (latest reported year), Alnylam Pharmaceuticals, Inc.
(ALNY) is pulling ahead at 65. 2% versus 19. 6% for ADMA Biologics, Inc. (ADMA). On earnings-per-share growth, the picture is similar: Alnylam Pharmaceuticals, Inc. grew EPS 206. 9% year-over-year, compared to -25. 9% for ADMA Biologics, Inc.. Over a 3-year CAGR, ALNY leads at 53. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — REVB or HALO or ALNY or ADMA?
ADMA Biologics, Inc.
(ADMA) is the more profitable company, earning 28. 8% net margin versus 0. 0% for Revelation Biosciences, Inc. — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus 0. 0% for REVB. At the gross margin level — before operating expenses — ALNY leads at 81. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is REVB or HALO or ALNY or ADMA more undervalued right now?
On forward earnings alone, Halozyme Therapeutics, Inc.
(HALO) trades at 8. 1x forward P/E versus 44. 2x for Alnylam Pharmaceuticals, Inc. — 36. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 165. 6% to $22. 50.
08Which pays a better dividend — REVB or HALO or ALNY or ADMA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is REVB or HALO or ALNY or ADMA better for a retirement portfolio?
For long-horizon retirement investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 56), +570. 7% 10Y return). Both have compounded well over 10 years (HALO: +570. 7%, REVB: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between REVB and HALO and ALNY and ADMA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: REVB is a small-cap quality compounder stock; HALO is a small-cap high-growth stock; ALNY is a mid-cap high-growth stock; ADMA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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