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Stock Comparison

REVB vs HALO vs ALNY vs ADMA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
REVB
Revelation Biosciences, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3M
5Y Perf.-100.0%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.68B
5Y Perf.+66.7%
ALNY
Alnylam Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$39.48B
5Y Perf.+127.8%
ADMA
ADMA Biologics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2.03B
5Y Perf.+315.2%

REVB vs HALO vs ALNY vs ADMA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
REVB logoREVB
HALO logoHALO
ALNY logoALNY
ADMA logoADMA
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$3M$7.68B$39.48B$2.03B
Revenue (TTM)$0.00$1.40B$4.29B$510M
Net Income (TTM)$-16M$317M$577M$165M
Gross Margin81.9%80.9%61.3%
Operating Margin58.4%17.5%42.1%
Forward P/E8.1x44.2x8.9x
Total Debt$747K$0.00$1.28B$80M
Cash & Equiv.$11M$134M$1.66B$88M

REVB vs HALO vs ALNY vs ADMALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

REVB
HALO
ALNY
ADMA
StockNov 20May 26Return
Revelation Bioscien… (REVB)1000.0-100.0%
Halozyme Therapeuti… (HALO)100166.7+66.7%
Alnylam Pharmaceuti… (ALNY)100227.8+127.8%
ADMA Biologics, Inc. (ADMA)100415.2+315.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: REVB vs HALO vs ALNY vs ADMA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HALO and ALNY are tied at the top with 2 categories each — the right choice depends on your priorities. Alnylam Pharmaceuticals, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. ADMA also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
REVB
Revelation Biosciences, Inc.
The Secondary Option

REVB lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
HALO
Halozyme Therapeutics, Inc.
The Income Pick

HALO has the current edge in this matchup, primarily because of its strength in income & stability and long-term compounding.

  • beta 0.56
  • 5.7% 10Y total return vs ALNY's 411.9%
  • Beta 0.56, current ratio 4.66x
  • Lower P/E (8.1x vs 8.9x)
Best for: income & stability and long-term compounding
ALNY
Alnylam Pharmaceuticals, Inc.
The Growth Play

ALNY is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 65.2%, EPS growth 206.9%, 3Y rev CAGR 53.0%
  • 65.2% revenue growth vs REVB's -100.0%
  • +7.0% vs REVB's -97.1%
Best for: growth exposure
ADMA
ADMA Biologics, Inc.
The Defensive Pick

ADMA is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 1.22, Low D/E 16.7%, current ratio 6.71x
  • 32.4% margin vs ALNY's 13.5%
  • 27.4% ROA vs REVB's -138.6%
Best for: sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthALNY logoALNY65.2% revenue growth vs REVB's -100.0%
ValueHALO logoHALOLower P/E (8.1x vs 8.9x)
Quality / MarginsADMA logoADMA32.4% margin vs ALNY's 13.5%
Stability / SafetyHALO logoHALOBeta 0.56 vs REVB's 1.36
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)ALNY logoALNY+7.0% vs REVB's -97.1%
Efficiency (ROA)ADMA logoADMA27.4% ROA vs REVB's -138.6%

REVB vs HALO vs ALNY vs ADMA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

REVBRevelation Biosciences, Inc.

Segment breakdown not available.

HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M
ALNYAlnylam Pharmaceuticals, Inc.
FY 2025
GIVLAARI
64.1%$308M
ONPATTRO
35.9%$173M
ADMAADMA Biologics, Inc.
FY 2024
ADMA BioManufacturing Segment
97.4%$416M
Plasma Collection Centers Segment
2.6%$11M

REVB vs HALO vs ALNY vs ADMA — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHALOLAGGINGALNY

Income & Cash Flow (Last 12 Months)

HALO leads this category, winning 3 of 6 comparable metrics.

ALNY and REVB operate at a comparable scale, with $4.3B and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to ALNY's 13.5%. On growth, ALNY holds the edge at +96.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricREVB logoREVBRevelation Biosci…HALO logoHALOHalozyme Therapeu…ALNY logoALNYAlnylam Pharmaceu…ADMA logoADMAADMA Biologics, I…
RevenueTrailing 12 months$0$1.4B$4.3B$510M
EBITDAEarnings before interest/tax-$10M$945M$677M$221M
Net IncomeAfter-tax profit-$16M$317M$577M$165M
Free Cash FlowCash after capex-$9M$645M$641M$108M
Gross MarginGross profit ÷ Revenue+81.9%+80.9%+61.3%
Operating MarginEBIT ÷ Revenue+58.4%+17.5%+42.1%
Net MarginNet income ÷ Revenue+22.7%+13.5%+32.4%
FCF MarginFCF ÷ Revenue+46.2%+15.0%+21.2%
Rev. Growth (YoY)Latest quarter vs prior year+51.6%+96.4%-0.3%
EPS Growth (YoY)Latest quarter vs prior year-28.4%-2.1%+4.4%+72.7%
HALO leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

HALO leads this category, winning 3 of 6 comparable metrics.

At 14.1x trailing earnings, ADMA trades at a 89% valuation discount to ALNY's 127.0x P/E. On an enterprise value basis, HALO's 8.3x EV/EBITDA is more attractive than ALNY's 70.2x.

MetricREVB logoREVBRevelation Biosci…HALO logoHALOHalozyme Therapeu…ALNY logoALNYAlnylam Pharmaceu…ADMA logoADMAADMA Biologics, I…
Market CapShares × price$3M$7.7B$39.5B$2.0B
Enterprise ValueMkt cap + debt − cash-$7M$7.5B$39.1B$2.0B
Trailing P/EPrice ÷ TTM EPS-0.04x25.46x127.00x14.12x
Forward P/EPrice ÷ next-FY EPS est.8.09x44.18x8.88x
PEG RatioP/E ÷ EPS growth rate1.11x
EV / EBITDAEnterprise value multiple8.34x70.17x10.15x
Price / SalesMarket cap ÷ Revenue5.50x10.63x3.98x
Price / BookPrice ÷ Book value/share0.07x165.47x50.50x4.35x
Price / FCFMarket cap ÷ FCF11.91x84.84x73.05x
HALO leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

Evenly matched — HALO and ADMA each lead in 3 of 9 comparable metrics.

HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-170 for REVB. REVB carries lower financial leverage with a 0.08x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALNY's 1.62x. On the Piotroski fundamental quality scale (0–9), ALNY scores 6/9 vs REVB's 4/9, reflecting solid financial health.

MetricREVB logoREVBRevelation Biosci…HALO logoHALOHalozyme Therapeu…ALNY logoALNYAlnylam Pharmaceu…ADMA logoADMAADMA Biologics, I…
ROE (TTM)Return on equity-169.6%+6.5%+98.3%+39.0%
ROA (TTM)Return on assets-138.6%+12.5%+11.8%+27.4%
ROICReturn on invested capital+73.4%+33.4%+36.0%
ROCEReturn on capital employed-126.9%+38.2%+15.3%+38.8%
Piotroski ScoreFundamental quality 0–94565
Debt / EquityFinancial leverage0.08x1.62x0.17x
Net DebtTotal debt minus cash-$10M-$134M-$379M-$8M
Cash & Equiv.Liquid assets$11M$134M$1.7B$88M
Total DebtShort + long-term debt$746,784$0$1.3B$80M
Interest CoverageEBIT ÷ Interest expense46.08x2.02x50.85x
Evenly matched — HALO and ADMA each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ADMA leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ADMA five years ago would be worth $48,678 today (with dividends reinvested), compared to $0 for REVB. Over the past 12 months, ALNY leads with a +7.0% total return vs REVB's -97.1%. The 3-year compound annual growth rate (CAGR) favors ADMA at 34.3% vs REVB's -94.7% — a key indicator of consistent wealth creation.

MetricREVB logoREVBRevelation Biosci…HALO logoHALOHalozyme Therapeu…ALNY logoALNYAlnylam Pharmaceu…ADMA logoADMAADMA Biologics, I…
YTD ReturnYear-to-date-68.6%-7.3%-26.1%-52.6%
1-Year ReturnPast 12 months-97.1%-7.1%+7.0%-64.1%
3-Year ReturnCumulative with dividends-100.0%+115.3%+40.9%+142.0%
5-Year ReturnCumulative with dividends-100.0%+37.0%+125.4%+386.8%
10-Year ReturnCumulative with dividends-100.0%+570.7%+411.9%+39.8%
CAGR (3Y)Annualised 3-year return-94.7%+29.1%+12.1%+34.3%
ADMA leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

HALO leads this category, winning 2 of 2 comparable metrics.

HALO is the less volatile stock with a 0.56 beta — it tends to amplify market swings less than REVB's 1.36 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HALO currently trades 79.3% from its 52-week high vs REVB's 2.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricREVB logoREVBRevelation Biosci…HALO logoHALOHalozyme Therapeu…ALNY logoALNYAlnylam Pharmaceu…ADMA logoADMAADMA Biologics, I…
Beta (5Y)Sensitivity to S&P 5001.36x0.56x0.71x1.22x
52-Week HighHighest price in past year$40.08$82.22$495.55$23.98
52-Week LowLowest price in past year$0.60$47.50$245.96$7.21
% of 52W HighCurrent price vs 52-week peak+2.5%+79.3%+59.7%+35.3%
RSI (14)Momentum oscillator 0–10029.752.443.837.9
Avg Volume (50D)Average daily shares traded76K1.4M1.1M7.3M
HALO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: HALO as "Buy", ALNY as "Buy", ADMA as "Buy". Consensus price targets imply 165.6% upside for ADMA (target: $23) vs 20.2% for HALO (target: $78).

MetricREVB logoREVBRevelation Biosci…HALO logoHALOHalozyme Therapeu…ALNY logoALNYAlnylam Pharmaceu…ADMA logoADMAADMA Biologics, I…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$78.33$445.67$22.50
# AnalystsCovering analysts27529
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+4.5%0.0%+1.6%
Insufficient data to determine a leader in this category.
Key Takeaway

HALO leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ADMA leads in 1 (Total Returns). 1 tied.

Best OverallHalozyme Therapeutics, Inc. (HALO)Leads 3 of 6 categories
Loading custom metrics...

REVB vs HALO vs ALNY vs ADMA: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is REVB or HALO or ALNY or ADMA a better buy right now?

For growth investors, Alnylam Pharmaceuticals, Inc.

(ALNY) is the stronger pick with 65. 2% revenue growth year-over-year, versus 19. 6% for ADMA Biologics, Inc. (ADMA). ADMA Biologics, Inc. (ADMA) offers the better valuation at 14. 1x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate Halozyme Therapeutics, Inc. (HALO) a "Buy" — based on 27 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — REVB or HALO or ALNY or ADMA?

On trailing P/E, ADMA Biologics, Inc.

(ADMA) is the cheapest at 14. 1x versus Alnylam Pharmaceuticals, Inc. at 127. 0x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 1x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — REVB or HALO or ALNY or ADMA?

Over the past 5 years, ADMA Biologics, Inc.

(ADMA) delivered a total return of +386. 8%, compared to -100. 0% for Revelation Biosciences, Inc. (REVB). Over 10 years, the gap is even starker: HALO returned +570. 7% versus REVB's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — REVB or HALO or ALNY or ADMA?

By beta (market sensitivity over 5 years), Halozyme Therapeutics, Inc.

(HALO) is the lower-risk stock at 0. 56β versus Revelation Biosciences, Inc. 's 1. 36β — meaning REVB is approximately 144% more volatile than HALO relative to the S&P 500. On balance sheet safety, Revelation Biosciences, Inc. (REVB) carries a lower debt/equity ratio of 8% versus 162% for Alnylam Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — REVB or HALO or ALNY or ADMA?

By revenue growth (latest reported year), Alnylam Pharmaceuticals, Inc.

(ALNY) is pulling ahead at 65. 2% versus 19. 6% for ADMA Biologics, Inc. (ADMA). On earnings-per-share growth, the picture is similar: Alnylam Pharmaceuticals, Inc. grew EPS 206. 9% year-over-year, compared to -25. 9% for ADMA Biologics, Inc.. Over a 3-year CAGR, ALNY leads at 53. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — REVB or HALO or ALNY or ADMA?

ADMA Biologics, Inc.

(ADMA) is the more profitable company, earning 28. 8% net margin versus 0. 0% for Revelation Biosciences, Inc. — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus 0. 0% for REVB. At the gross margin level — before operating expenses — ALNY leads at 81. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is REVB or HALO or ALNY or ADMA more undervalued right now?

On forward earnings alone, Halozyme Therapeutics, Inc.

(HALO) trades at 8. 1x forward P/E versus 44. 2x for Alnylam Pharmaceuticals, Inc. — 36. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 165. 6% to $22. 50.

08

Which pays a better dividend — REVB or HALO or ALNY or ADMA?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is REVB or HALO or ALNY or ADMA better for a retirement portfolio?

For long-horizon retirement investors, Halozyme Therapeutics, Inc.

(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 56), +570. 7% 10Y return). Both have compounded well over 10 years (HALO: +570. 7%, REVB: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between REVB and HALO and ALNY and ADMA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: REVB is a small-cap quality compounder stock; HALO is a small-cap high-growth stock; ALNY is a mid-cap high-growth stock; ADMA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Revenue Growth > 25%
  • Net Margin > 13%
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  • Market Cap > $100B
  • Revenue Growth > 48%
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