Drug Manufacturers - Specialty & Generic
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RGC vs NUVB vs PRAX vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
RGC vs NUVB vs PRAX vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $15.56B | $1.67B | $9.63B | $5.53B |
| Revenue (TTM) | $0.00 | $143M | $-92K | $0.00 |
| Net Income (TTM) | $-5M | $-146M | $-327M | $-464M |
| Gross Margin | — | 91.6% | — | — |
| Operating Margin | — | -105.0% | — | — |
| Total Debt | $86K | $10M | $110K | $98K |
| Cash & Equiv. | $3M | $164M | $357M | $714M |
RGC vs NUVB vs PRAX vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 21 | May 26 | Return |
|---|---|---|---|
| Regencell Bioscienc… (RGC) | 100 | 13041.9 | +12941.9% |
| Nuvation Bio Inc. (NUVB) | 100 | 55.8 | -44.2% |
| Praxis Precision Me… (PRAX) | 100 | 142.4 | +42.4% |
| Immunovant, Inc. (IMVT) | 100 | 260.2 | +160.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: RGC vs NUVB vs PRAX vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
RGC is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.
- beta 0.72
- 119.3% 10Y total return vs IMVT's 173.6%
- Lower volatility, beta 0.72, Low D/E 1.0%, current ratio 41.92x
- Beta 0.72, current ratio 41.92x
NUVB carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 7.0%, EPS growth 71.6%
- 7.0% revenue growth vs PRAX's -100.0%
- -23.8% ROA vs RGC's -60.2%, ROIC -54.3% vs -43.8%
PRAX is the clearest fit if your priority is momentum.
- +7.7% vs IMVT's +96.1%
IMVT is the clearest fit if your priority is quality.
- 3.2% margin vs NUVB's -102.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 7.0% revenue growth vs PRAX's -100.0% | |
| Quality / Margins | 3.2% margin vs NUVB's -102.1% | |
| Stability / Safety | Beta 0.72 vs NUVB's 2.04, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +7.7% vs IMVT's +96.1% | |
| Efficiency (ROA) | -23.8% ROA vs RGC's -60.2%, ROIC -54.3% vs -43.8% |
RGC vs NUVB vs PRAX vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
RGC vs NUVB vs PRAX vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NUVB leads in 1 of 6 categories
RGC leads 1 • PRAX leads 0 • IMVT leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NUVB leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
NUVB and PRAX operate at a comparable scale, with $143M and -$92,000 in trailing revenue.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $143M | -$92,000 | $0 |
| EBITDAEarnings before interest/tax | -$4M | -$145M | -$357M | -$487M |
| Net IncomeAfter-tax profit | -$5M | -$146M | -$327M | -$464M |
| Free Cash FlowCash after capex | -$7M | -$126M | -$283M | -$423M |
| Gross MarginGross profit ÷ Revenue | — | +91.6% | — | — |
| Operating MarginEBIT ÷ Revenue | — | -105.0% | — | — |
| Net MarginNet income ÷ Revenue | — | -102.1% | — | — |
| FCF MarginFCF ÷ Revenue | — | -88.1% | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +26.0% | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | — | +106.3% | +2.7% | +19.7% |
Valuation Metrics
Evenly matched — RGC and NUVB each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $15.6B | $1.7B | $9.6B | $5.5B |
| Enterprise ValueMkt cap + debt − cash | $15.6B | $1.5B | $9.3B | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -3617.24x | -8.03x | -24.72x | -9.97x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 26.61x | — | — |
| Price / BookPrice ÷ Book value/share | 1893.39x | 5.38x | 8.54x | 5.83x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
Evenly matched — RGC and NUVB each lead in 3 of 8 comparable metrics.
Profitability & Efficiency
PRAX delivers a -43.0% return on equity — every $100 of shareholder capital generates $-43 in annual profit, vs $-67 for RGC. PRAX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NUVB's 0.03x. On the Piotroski fundamental quality scale (0–9), RGC scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -67.0% | -44.1% | -43.0% | -47.1% |
| ROA (TTM)Return on assets | -60.2% | -23.8% | -40.2% | -44.1% |
| ROICReturn on invested capital | -43.8% | -54.3% | -65.0% | — |
| ROCEReturn on capital employed | -46.8% | -42.8% | -49.3% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 3 | 2 |
| Debt / EquityFinancial leverage | 0.01x | 0.03x | 0.00x | 0.00x |
| Net DebtTotal debt minus cash | -$3M | -$154M | -$357M | -$714M |
| Cash & Equiv.Liquid assets | $3M | $164M | $357M | $714M |
| Total DebtShort + long-term debt | $85,741 | $10M | $110,000 | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | — | -162.11x | — | — |
Total Returns (Dividends Reinvested)
RGC leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in RGC five years ago would be worth $1,138,979 today (with dividends reinvested), compared to $4,173 for NUVB. Over the past 12 months, PRAX leads with a +775.0% total return vs IMVT's +96.1%. The 3-year compound annual growth rate (CAGR) favors RGC at 2.6% vs IMVT's 12.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +53.2% | -43.8% | +16.4% | +5.1% |
| 1-Year ReturnPast 12 months | +529.4% | +136.3% | +775.0% | +96.1% |
| 3-Year ReturnCumulative with dividends | +4525.9% | +197.5% | +1976.5% | +40.9% |
| 5-Year ReturnCumulative with dividends | +11289.8% | -58.3% | -20.8% | +62.4% |
| 10-Year ReturnCumulative with dividends | +11926.8% | -51.8% | -20.1% | +173.6% |
| CAGR (3Y)Annualised 3-year return | +2.6% | +43.8% | +174.9% | +12.1% |
Risk & Volatility
Evenly matched — RGC and PRAX each lead in 1 of 2 comparable metrics.
Risk & Volatility
RGC is the less volatile stock with a 0.72 beta — it tends to amplify market swings less than NUVB's 2.04 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PRAX currently trades 93.6% from its 52-week high vs RGC's 37.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.72x | 2.04x | 1.55x | 1.37x |
| 52-Week HighHighest price in past year | $83.60 | $9.75 | $356.00 | $30.09 |
| 52-Week LowLowest price in past year | $3.93 | $1.57 | $35.18 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +37.6% | +49.4% | +93.6% | +90.5% |
| RSI (14)Momentum oscillator 0–100 | 47.5 | 59.1 | 55.6 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 139K | 4.3M | 378K | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: RGC as "Hold", NUVB as "Buy", PRAX as "Buy", IMVT as "Buy". Consensus price targets imply 157.3% upside for NUVB (target: $12) vs 63.3% for PRAX (target: $544).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $12.40 | $544.40 | $45.50 |
| # AnalystsCovering analysts | 4 | 9 | 16 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
NUVB leads in 1 of 6 categories (Income & Cash Flow). RGC leads in 1 (Total Returns). 3 tied.
RGC vs NUVB vs PRAX vs IMVT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is RGC or NUVB or PRAX or IMVT a better buy right now?
For growth investors, Nuvation Bio Inc.
(NUVB) is the stronger pick with 699. 0% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). Analysts rate Nuvation Bio Inc. (NUVB) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — RGC or NUVB or PRAX or IMVT?
Over the past 5 years, Regencell Bioscience Holdings Limited (RGC) delivered a total return of +112.
9%, compared to -58. 3% for Nuvation Bio Inc. (NUVB). Over 10 years, the gap is even starker: RGC returned +119. 3% versus NUVB's -51. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — RGC or NUVB or PRAX or IMVT?
By beta (market sensitivity over 5 years), Regencell Bioscience Holdings Limited (RGC) is the lower-risk stock at 0.
72β versus Nuvation Bio Inc. 's 2. 04β — meaning NUVB is approximately 183% more volatile than RGC relative to the S&P 500. On balance sheet safety, Praxis Precision Medicines, Inc. (PRAX) carries a lower debt/equity ratio of 0% versus 3% for Nuvation Bio Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — RGC or NUVB or PRAX or IMVT?
By revenue growth (latest reported year), Nuvation Bio Inc.
(NUVB) is pulling ahead at 699. 0% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: Nuvation Bio Inc. grew EPS 71. 6% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — RGC or NUVB or PRAX or IMVT?
Regencell Bioscience Holdings Limited (RGC) is the more profitable company, earning 0.
0% net margin versus -325. 3% for Nuvation Bio Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RGC leads at 0. 0% versus -338. 7% for NUVB. At the gross margin level — before operating expenses — NUVB leads at 86. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — RGC or NUVB or PRAX or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is RGC or NUVB or PRAX or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Regencell Bioscience Holdings Limited (RGC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
72), +119. 3% 10Y return). Nuvation Bio Inc. (NUVB) carries a higher beta of 2. 04 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RGC: +119. 3%, NUVB: -51. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between RGC and NUVB and PRAX and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: RGC is a mid-cap quality compounder stock; NUVB is a small-cap high-growth stock; PRAX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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