Drug Manufacturers - Specialty & Generic
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4 / 10Stock Comparison
SBFM vs SNDX vs IMVT vs CRL
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Diagnostics & Research
SBFM vs SNDX vs IMVT vs CRL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology | Medical - Diagnostics & Research |
| Market Cap | $737K | $1.90B | $5.88B | $8.76B |
| Revenue (TTM) | $36M | $217M | $0.00 | $4.03B |
| Net Income (TTM) | $-6M | $-243M | $-464M | $-185M |
| Gross Margin | 33.3% | 98.0% | — | 31.9% |
| Operating Margin | -17.9% | -102.9% | — | 11.8% |
| Forward P/E | — | — | — | 16.0x |
| Total Debt | $952K | $346M | $98K | $3.07B |
| Cash & Equiv. | $10M | $135M | $714M | $214M |
SBFM vs SNDX vs IMVT vs CRL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Sunshine Biopharma,… (SBFM) | 100 | 0.6 | -99.4% |
| Syndax Pharmaceutic… (SNDX) | 100 | 132.7 | +32.7% |
| Immunovant, Inc. (IMVT) | 100 | 112.8 | +12.8% |
| Charles River Labor… (CRL) | 100 | 98.9 | -1.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: SBFM vs SNDX vs IMVT vs CRL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
SBFM is the clearest fit if your priority is growth exposure.
- Rev growth 44.7%, EPS growth 97.9%, 3Y rev CAGR 434.5%
SNDX carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- Dividend streak 1 yrs, beta 0.69
- Lower volatility, beta 0.69, current ratio 4.40x
- Beta 0.69, current ratio 4.40x
- 6.3% revenue growth vs IMVT's -21.3%
IMVT is the #2 pick in this set and the best alternative if long-term compounding is your priority.
- 190.9% 10Y total return vs CRL's 114.0%
- 3.2% margin vs SNDX's -112.0%
- +102.4% vs SBFM's -14.6%
CRL is the clearest fit if your priority is efficiency.
- -2.5% ROA vs SNDX's -45.2%, ROIC 6.3% vs -54.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 6.3% revenue growth vs IMVT's -21.3% | |
| Quality / Margins | 3.2% margin vs SNDX's -112.0% | |
| Stability / Safety | Beta 0.69 vs CRL's 1.44 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +102.4% vs SBFM's -14.6% | |
| Efficiency (ROA) | -2.5% ROA vs SNDX's -45.2%, ROIC 6.3% vs -54.2% |
SBFM vs SNDX vs IMVT vs CRL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
SBFM vs SNDX vs IMVT vs CRL — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
SBFM leads in 1 of 6 categories
CRL leads 1 • IMVT leads 1 • SNDX leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — SNDX and CRL each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
CRL and IMVT operate at a comparable scale, with $4.0B and $0 in trailing revenue. CRL is the more profitable business, keeping -4.6% of every revenue dollar as net income compared to SNDX's -112.0%.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $36M | $217M | $0 | $4.0B |
| EBITDAEarnings before interest/tax | -$6M | -$218M | -$487M | $824M |
| Net IncomeAfter-tax profit | -$6M | -$243M | -$464M | -$185M |
| Free Cash FlowCash after capex | -$9M | -$278M | -$423M | $391M |
| Gross MarginGross profit ÷ Revenue | +33.3% | +98.0% | — | +31.9% |
| Operating MarginEBIT ÷ Revenue | -17.9% | -102.9% | — | +11.8% |
| Net MarginNet income ÷ Revenue | -17.4% | -112.0% | — | -4.6% |
| FCF MarginFCF ÷ Revenue | -26.1% | -128.2% | — | +9.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | +1.2% | +2.2% | — | +1.2% |
| EPS Growth (YoY)Latest quarter vs prior year | +21.5% | +100.0% | +19.7% | -160.0% |
Valuation Metrics
SBFM leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $736,836 | $1.9B | $5.9B | $8.8B |
| Enterprise ValueMkt cap + debt − cash | -$8M | $2.1B | $5.2B | $11.6B |
| Trailing P/EPrice ÷ TTM EPS | -0.14x | -6.53x | -10.60x | -61.04x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 16.00x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 12.75x |
| Price / SalesMarket cap ÷ Revenue | 0.02x | 11.00x | — | 2.18x |
| Price / BookPrice ÷ Book value/share | 0.03x | 28.80x | 6.20x | 2.74x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 16.90x |
Profitability & Efficiency
CRL leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
CRL delivers a -5.7% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-3 for SNDX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SNDX's 5.36x. On the Piotroski fundamental quality scale (0–9), CRL scores 4/9 vs SBFM's 1/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -24.6% | -2.6% | -47.1% | -5.7% |
| ROA (TTM)Return on assets | -19.7% | -45.2% | -44.1% | -2.5% |
| ROICReturn on invested capital | -42.9% | -54.2% | — | +6.3% |
| ROCEReturn on capital employed | -25.2% | -53.0% | -66.1% | +8.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 2 | 2 | 4 |
| Debt / EquityFinancial leverage | 0.04x | 5.36x | 0.00x | 0.95x |
| Net DebtTotal debt minus cash | -$9M | $212M | -$714M | $2.9B |
| Cash & Equiv.Liquid assets | $10M | $135M | $714M | $214M |
| Total DebtShort + long-term debt | $952,480 | $346M | $98,000 | $3.1B |
| Interest CoverageEBIT ÷ Interest expense | -757.53x | -2.31x | — | 4.29x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $18,445 today (with dividends reinvested), compared to $1 for SBFM. Over the past 12 months, IMVT leads with a +102.4% total return vs SBFM's -14.6%. The 3-year compound annual growth rate (CAGR) favors IMVT at 14.4% vs SBFM's -89.9% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -18.0% | +0.9% | +11.7% | -12.3% |
| 1-Year ReturnPast 12 months | -14.6% | +95.2% | +102.4% | +25.7% |
| 3-Year ReturnCumulative with dividends | -99.9% | +5.9% | +49.8% | -6.5% |
| 5-Year ReturnCumulative with dividends | -100.0% | +37.4% | +84.4% | -46.6% |
| 10-Year ReturnCumulative with dividends | -100.0% | +50.1% | +190.9% | +114.0% |
| CAGR (3Y)Annualised 3-year return | -89.9% | +1.9% | +14.4% | -2.2% |
Risk & Volatility
Evenly matched — SNDX and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
SNDX is the less volatile stock with a 0.69 beta — it tends to amplify market swings less than CRL's 1.44 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 96.2% from its 52-week high vs SBFM's 43.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.33x | 0.69x | 1.36x | 1.44x |
| 52-Week HighHighest price in past year | $2.43 | $25.58 | $30.09 | $228.88 |
| 52-Week LowLowest price in past year | $0.95 | $8.58 | $13.36 | $132.58 |
| % of 52W HighCurrent price vs 52-week peak | +43.2% | +84.0% | +96.2% | +77.6% |
| RSI (14)Momentum oscillator 0–100 | 56.2 | 40.7 | 50.6 | 57.4 |
| Avg Volume (50D)Average daily shares traded | 37K | 1.6M | 1.4M | 792K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: SNDX as "Buy", IMVT as "Buy", CRL as "Buy". Consensus price targets imply 93.1% upside for SNDX (target: $42) vs 16.2% for CRL (target: $206).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $41.50 | $45.50 | $206.43 |
| # AnalystsCovering analysts | — | 22 | 23 | 36 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 1 | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +100.0% | 0.0% | 0.0% | +4.1% |
SBFM leads in 1 of 6 categories (Valuation Metrics). CRL leads in 1 (Profitability & Efficiency). 2 tied.
SBFM vs SNDX vs IMVT vs CRL: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is SBFM or SNDX or IMVT or CRL a better buy right now?
For growth investors, Syndax Pharmaceuticals, Inc.
(SNDX) is the stronger pick with 627. 8% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). Analysts rate Syndax Pharmaceuticals, Inc. (SNDX) a "Buy" — based on 22 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — SBFM or SNDX or IMVT or CRL?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +84. 4%, compared to -100. 0% for Sunshine Biopharma, Inc. (SBFM). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus SBFM's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — SBFM or SNDX or IMVT or CRL?
By beta (market sensitivity over 5 years), Syndax Pharmaceuticals, Inc.
(SNDX) is the lower-risk stock at 0. 69β versus Charles River Laboratories International, Inc. 's 1. 44β — meaning CRL is approximately 109% more volatile than SNDX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 5% for Syndax Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — SBFM or SNDX or IMVT or CRL?
By revenue growth (latest reported year), Syndax Pharmaceuticals, Inc.
(SNDX) is pulling ahead at 627. 8% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: Sunshine Biopharma, Inc. grew EPS 97. 9% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, SBFM leads at 434. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — SBFM or SNDX or IMVT or CRL?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -165. 6% for Syndax Pharmaceuticals, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CRL leads at 12. 6% versus -158. 4% for SNDX. At the gross margin level — before operating expenses — SNDX leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is SBFM or SNDX or IMVT or CRL more undervalued right now?
Analyst consensus price targets imply the most upside for SNDX: 93.
1% to $41. 50.
07Which pays a better dividend — SBFM or SNDX or IMVT or CRL?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is SBFM or SNDX or IMVT or CRL better for a retirement portfolio?
For long-horizon retirement investors, Syndax Pharmaceuticals, Inc.
(SNDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 69)). Both have compounded well over 10 years (SNDX: +50. 1%, SBFM: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between SBFM and SNDX and IMVT and CRL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: SBFM is a small-cap high-growth stock; SNDX is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; CRL is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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