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SER vs BIIB
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
SER vs BIIB — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General |
| Market Cap | $20M | $28.25B |
| Revenue (TTM) | $116K | $9.86B |
| Net Income (TTM) | $-19M | $1.37B |
| Gross Margin | 56.9% | 69.8% |
| Operating Margin | -201.4% | 15.6% |
| Forward P/E | — | 13.1x |
| Total Debt | $268K | $6.95B |
| Cash & Equiv. | $4M | $3.01B |
SER vs BIIB — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Serina Therapeutics… (SER) | 100 | 4.3 | -95.7% |
| Biogen Inc. (BIIB) | 100 | 63.0 | -37.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: SER vs BIIB
Each card shows where this stock fits in a portfolio — not just who wins on paper.
In this particular matchup, SER is outpaced on most metrics by others in the set.
BIIB carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 0 yrs, beta 0.64
- Rev growth 1.4%, EPS growth -21.1%, 3Y rev CAGR -1.2%
- -29.2% 10Y total return vs SER's -98.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 1.4% revenue growth vs SER's -98.2% | |
| Quality / Margins | 13.9% margin vs SER's -160.2% | |
| Stability / Safety | Beta 0.64 vs SER's 1.24, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +63.3% vs SER's -68.5% | |
| Efficiency (ROA) | 4.7% ROA vs SER's -213.6% |
SER vs BIIB — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
SER vs BIIB — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
BIIB leads this category, winning 6 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BIIB is the larger business by revenue, generating $9.9B annually — 84977.6x SER's $116,000. BIIB is the more profitable business, keeping 13.9% of every revenue dollar as net income compared to SER's -160.2%. On growth, BIIB holds the edge at +1.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $116,000 | $9.9B |
| EBITDAEarnings before interest/tax | -$23M | $2.4B |
| Net IncomeAfter-tax profit | -$19M | $1.4B |
| Free Cash FlowCash after capex | -$17M | $2.6B |
| Gross MarginGross profit ÷ Revenue | +56.9% | +69.8% |
| Operating MarginEBIT ÷ Revenue | -201.4% | +15.6% |
| Net MarginNet income ÷ Revenue | -160.2% | +13.9% |
| FCF MarginFCF ÷ Revenue | -142.5% | +26.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | +1.9% |
| EPS Growth (YoY)Latest quarter vs prior year | -4.4% | +31.1% |
Valuation Metrics
BIIB leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $20M | $28.3B |
| Enterprise ValueMkt cap + debt − cash | $16M | $32.2B |
| Trailing P/EPrice ÷ TTM EPS | -1.20x | 21.67x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 13.12x |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | 11.45x |
| Price / SalesMarket cap ÷ Revenue | 348.60x | 2.88x |
| Price / BookPrice ÷ Book value/share | 26.22x | 1.54x |
| Price / FCFMarket cap ÷ FCF | — | 13.78x |
Profitability & Efficiency
BIIB leads this category, winning 6 of 8 comparable metrics.
Profitability & Efficiency
BIIB delivers a 7.5% return on equity — every $100 of shareholder capital generates $8 in annual profit, vs $-14 for SER. BIIB carries lower financial leverage with a 0.38x debt-to-equity ratio, signaling a more conservative balance sheet compared to SER's 0.53x. On the Piotroski fundamental quality scale (0–9), BIIB scores 5/9 vs SER's 2/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -14.0% | +7.5% |
| ROA (TTM)Return on assets | -2.1% | +4.7% |
| ROICReturn on invested capital | — | +6.5% |
| ROCEReturn on capital employed | -2.9% | +7.7% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 5 |
| Debt / EquityFinancial leverage | 0.53x | 0.38x |
| Net DebtTotal debt minus cash | -$3M | $3.9B |
| Cash & Equiv.Liquid assets | $4M | $3.0B |
| Total DebtShort + long-term debt | $268,000 | $6.9B |
| Interest CoverageEBIT ÷ Interest expense | -581.22x | 6.91x |
Total Returns (Dividends Reinvested)
BIIB leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in BIIB five years ago would be worth $6,984 today (with dividends reinvested), compared to $387 for SER. Over the past 12 months, BIIB leads with a +63.3% total return vs SER's -68.5%. The 3-year compound annual growth rate (CAGR) favors BIIB at -15.2% vs SER's -55.6% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -12.9% | +7.6% |
| 1-Year ReturnPast 12 months | -68.5% | +63.3% |
| 3-Year ReturnCumulative with dividends | -91.3% | -39.1% |
| 5-Year ReturnCumulative with dividends | -96.1% | -30.2% |
| 10-Year ReturnCumulative with dividends | -98.1% | -29.2% |
| CAGR (3Y)Annualised 3-year return | -55.6% | -15.2% |
Risk & Volatility
BIIB leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
BIIB is the less volatile stock with a 0.64 beta — it tends to amplify market swings less than SER's 1.24 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIIB currently trades 94.6% from its 52-week high vs SER's 22.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.14x | 0.60x |
| 52-Week HighHighest price in past year | $7.92 | $202.41 |
| 52-Week LowLowest price in past year | $1.22 | $115.25 |
| % of 52W HighCurrent price vs 52-week peak | +22.9% | +94.6% |
| RSI (14)Momentum oscillator 0–100 | 45.1 | 56.6 |
| Avg Volume (50D)Average daily shares traded | 3.8M | 1.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $211.42 |
| # AnalystsCovering analysts | — | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | 0 |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
BIIB leads in 5 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics.
SER vs BIIB: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is SER or BIIB a better buy right now?
For growth investors, Biogen Inc.
(BIIB) is the stronger pick with 1. 4% revenue growth year-over-year, versus -98. 2% for Serina Therapeutics, Inc. (SER). Biogen Inc. (BIIB) offers the better valuation at 21. 7x trailing P/E (13. 1x forward), making it the more compelling value choice. Analysts rate Biogen Inc. (BIIB) a "Buy" — based on 48 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — SER or BIIB?
Over the past 5 years, Biogen Inc.
(BIIB) delivered a total return of -30. 2%, compared to -96. 1% for Serina Therapeutics, Inc. (SER). Over 10 years, the gap is even starker: BIIB returned -28. 4% versus SER's -98. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — SER or BIIB?
By beta (market sensitivity over 5 years), Biogen Inc.
(BIIB) is the lower-risk stock at 0. 60β versus Serina Therapeutics, Inc. 's 1. 14β — meaning SER is approximately 89% more volatile than BIIB relative to the S&P 500. On balance sheet safety, Biogen Inc. (BIIB) carries a lower debt/equity ratio of 38% versus 53% for Serina Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — SER or BIIB?
By revenue growth (latest reported year), Biogen Inc.
(BIIB) is pulling ahead at 1. 4% versus -98. 2% for Serina Therapeutics, Inc. (SER). On earnings-per-share growth, the picture is similar: Biogen Inc. grew EPS -21. 1% year-over-year, compared to -339. 7% for Serina Therapeutics, Inc.. Over a 3-year CAGR, BIIB leads at -1. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — SER or BIIB?
Biogen Inc.
(BIIB) is the more profitable company, earning 13. 2% net margin versus -198. 9% for Serina Therapeutics, Inc. — meaning it keeps 13. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BIIB leads at 19. 1% versus -304. 4% for SER. At the gross margin level — before operating expenses — BIIB leads at 70. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — SER or BIIB?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is SER or BIIB better for a retirement portfolio?
For long-horizon retirement investors, Biogen Inc.
(BIIB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 60)). Both have compounded well over 10 years (BIIB: -28. 4%, SER: -98. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between SER and BIIB?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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