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SERSerina Therapeutics, Inc.
$1.89$20M
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SER logoSerina Therapeutics, Inc.(SER)Earnings, Financials & Key Ratios

SER•NYSE
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Delivery Technology Platforms
AboutSerina Therapeutics, Inc., a biotechnology company, develops drugs to treat neurological diseases and pain. Its lead product candidate is SER 252, a POZ conjugate for the treatment of Parkinson's disease. The company also develops SER 227 for long-acting pain relief; SER 214 to treat Parkinson's disease; and SER 228 for the treatment of epilepsy. In addition, it develops POZ technology in lipid nanoparticle delivered ribonucleic acid vaccines for infectious diseases. Serina Therapeutics, Inc. was founded in 2006 and is based in Huntsville, Alabama.Show more
  • Revenue$0-100.0%
  • EBITDA-$24M-42.1%
  • Net Income-$19M-72.2%
  • EPS (Diluted)-1.91-26.5%
  • ROE-8145.22%-271.4%

SER Key Insights

Serina Therapeutics, Inc. (SER) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Profits declining 12.0% over 5 years
  • ✗Weak Piotroski F-Score: 2/9
  • ✗Shares diluted 38.5% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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SER Price & Volume

Serina Therapeutics, Inc. (SER) stock price & volume — 10-year historical chart

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SER Growth Metrics

Serina Therapeutics, Inc. (SER) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-2164.86%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-1870%

Return on Capital

10 Years-396.71%
5 Years-474.56%
3 Years-592.68%
Last Year-620.24%

SER Peer Comparison

Serina Therapeutics, Inc. (SER) competitors in Drug Delivery Technology Platforms — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
PRTA logoPRTAProthena Corporation plcDirect Competitor467.51M8.93-1.97-92.84%-260.92%-49.88%0.05
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.7B21.629.4411.87%34.3%35.65%0.04
NRXP logoNRXPNRx Pharmaceuticals, Inc.Direct Competitor68.62M3.97-2.96-10.7%
BIIB logoBIIBBiogen Inc.Product Competitor29.02B196.5822.261.39%13.92%7.55%0.38
ALNY logoALNYAlnylam Pharmaceuticals, Inc.Product Competitor37.1B278.09119.3565.19%13.46%98.29%1.62
IONS logoIONSIonis Pharmaceuticals, Inc.Product Competitor12.25B74.12-31.1433.87%-30.87%-58.57%5.35
ARVN logoARVNArvinas, Inc.Product Competitor494.88M7.67-5.99-0.3%-247.54%-44.39%0.02
PTGX logoPTGXProtagonist Therapeutics, Inc.Product Competitor7.26B112.86-55.05-89.41%-6.48%-17.76%0.02

Compare SER vs Peers

Serina Therapeutics, Inc. (SER) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRTA

Most directly comparable listed peer for SER.

Scale Benchmark

vs ALNY

Larger-name benchmark to compare SER against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRTA, ACAD, NRXP, BIIB

SER Income Statement

Serina Therapeutics, Inc. (SER) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
1.4M1.4M1.73M54K3.46M500K3.15M56K0130K
Revenue Growth %
-15.73%-0.57%23.78%-96.88%6316.21%-85.57%530.6%-98.22%-100%-
Cost of Goods Sold
685K841K998.5K1.28M3.8M090K194K034K
COGS % of Revenue
48.79%60.24%57.78%2372.22%109.64%-2.85%346.43%--
Gross Profit
719K▲ 0%
555K▼ 22.8%
729.5K▲ 31.4%
-1.23M▼ 268.2%
-333.84K▲ 72.8%
500K▲ 249.8%
3.06M▲ 512.6%
-138K▼ 104.5%
0▲ 100.0%
96K▲ 0%
Gross Margin %
51.21%39.76%42.22%-2272.22%-9.64%100%97.15%-246.43%-73.85%
Gross Profit Growth %
-4.77%-22.81%31.44%-268.2%72.79%249.77%512.6%-104.51%100%-
Operating Expenses
9.14M11M13.29M9.18M1.3M2.77M6.19M16.91M24.02M24.54M
OpEx % of Revenue
650.71%787.97%769.01%17000%37.45%554.07%196.38%30196.43%--
Selling, General & Admin
3.87M5.65M7.94M5.6M1.3M1.29M3.89M9.43M11M11.17M
SG&A % of Revenue
275.57%404.51%459.64%10366.67%37.45%257.76%123.5%16839.29%--
Research & Development
5.27M5.35M5.35M3.58M3.8M1.57M2.39M7.48M13.15M13.4M
R&D % of Revenue
375.14%383.45%309.38%6633.33%109.64%314.62%75.74%13357.14%--
Other Operating Expenses
0000-3.8M-91.5K-90K0-130K-16K
Operating Income
-8.42M▲ 0%
-10.45M▼ 24.1%
-12.56M▼ 20.2%
-10.41M▲ 17.1%
-1.63M▲ 84.3%
-2.27M▼ 39.2%
-3.13M▼ 37.8%
-17.05M▼ 444.8%
-24.02M▼ 40.9%
-24.44M▲ 0%
Operating Margin %
-599.5%-748.21%-726.79%-19272.22%-47.09%-454.07%-99.24%-30442.86%--18803.08%
Operating Income Growth %
33.93%-24.09%-20.24%17.14%84.32%-39.16%-37.82%-444.84%-40.91%-
EBITDA
-7.74M-9.91M-11.61M-9.15M-1.6M-2.21M-3.04M-16.85M-23.95M-24.37M
EBITDA Margin %
-550.93%-709.89%-671.76%-16948.15%-46.13%-441.82%-96.38%-30096.43%--18746.15%
EBITDA Growth %
34.97%-28.12%-17.13%21.16%82.54%-38.23%-37.57%-454.59%-42.1%-19.47%
D&A (Non-Cash Add-back)
682K535K951K1.25M33.37K61.27K90K194K73K74K
EBIT
-8.42M-7.73M-12.24M-9.99M-1.26M-2.67M5.83M-10.68M-18.98M-20.44M
Net Interest Income
-12K116K29K-404K7.76K-14.12K-558K-526K-213K-24K
Interest Income
0116K29K010.86K1.76K0000
Interest Expense
12K00404K3.09K15.88K558K526K213K24K
Other Income/Expense
1.78M2.71M323K8K366.81K-411.74K8.4M5.84M4.83M3.18M
Pretax Income
-6.64M▲ 0%
-7.73M▼ 16.5%
-12.24M▼ 58.3%
-10.4M▲ 15.0%
-1.26M▲ 87.8%
-2.68M▼ 112.1%
5.27M▲ 296.4%
-11.21M▼ 312.7%
-19.2M▼ 71.3%
-21.27M▲ 0%
Pretax Margin %
-472.72%-553.8%-708.1%-19257.41%-36.5%-536.42%167.11%-20012.5%--16358.46%
Income Tax
00148K0000018K25K
Effective Tax Rate %
0%0%-1.21%0%0%0%0%0%-0.09%-0.12%
Net Income
-6.58M▲ 0%
-7.5M▼ 14.0%
-12.15M▼ 62.0%
-10.87M▲ 10.6%
-1.26M▲ 88.4%
-2.68M▼ 112.1%
5.27M▲ 296.4%
-11.14M▼ 311.4%
-19.18M▼ 72.2%
-21.27M▲ 0%
Net Margin %
-468.66%-537.39%-703.36%-20120.37%-36.5%-536.42%167.11%-19894.64%--16359.23%
Net Income Growth %
57.53%-14.01%-62.01%10.61%88.36%-112.07%296.45%-311.44%-72.17%-2164.86%
Net Income (Continuing)
-6.64M-7.73M-12.38M-10.4M-1.26M-2.68M5.27M-11.21M-19.21M-21.29M
Discontinued Operations
000-471K000000
Minority Interest
1.04M784K399K-280K-43K-103K0-133K00
EPS (Diluted)
-6.46▲ 0%
-7.56▼ 17.0%
-11.47▼ 51.7%
-10.14▲ 11.6%
-0.59▲ 94.2%
-2.49▼ 322.0%
0.63▲ 125.3%
-1.51▼ 339.7%
-1.91▼ 26.5%
-1.77▲ 0%
EPS Growth %
57.53%-17.03%-51.72%11.6%94.18%-322.03%125.3%-339.68%-26.49%-1870%
EPS (Basic)
-6.46-7.56-11.47-10.14-0.59-2.490.63-1.51-1.91-
Diluted Shares Outstanding
1.02M992.72K1.06M1.07M1.08M1.08M8.41M7.36M10.19M12.05M
Basic Shares Outstanding
1.02M992.72K1.06M1.07M1.08M1.08M8.41M7.36M10.19M12.05M
Dividend Payout Ratio
----------

SER Balance Sheet

Serina Therapeutics, Inc. (SER) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
7.59M7.85M4.05M2.28M2.23M2.45M7.62M5.68M6.08M26.47M
Cash & Short-Term Investments
7.38M6.71M2.35M527K584K645K7.62M3.67M3.06M24.53M
Cash Only
7.38M6.71M2.35M527K584K645K7.62M3.67M3.06M24.53M
Short-Term Investments
0000000000
Accounts Receivable
107K131K363K326K25K4K0000
Days Sales Outstanding
27.8234.2576.682.2K2.632.92----
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
111K1.01M1.34M1.43M1.63M1.8M077K3.02M333K
Total Non-Current Assets
2.04M2.82M3.39M1.64M920K788K1.35M1.05M871K825K
Property, Plant & Equipment
129K90K1.13M0001.35M1.05M842K800K
Fixed Asset Turnover
10.88x15.51x1.53x---2.34x0.05x-0.15x
Goodwill
0000000000
Intangible Assets
002.15M1.59M0738K0000
Long-Term Investments
00050K50K50K0000
Other Non-Current Assets
1.91M2.73M111K0870K00029K25K
Total Assets
9.63M▲ 0%
10.67M▲ 10.8%
7.44M▼ 30.3%
3.92M▼ 47.3%
3.15M▼ 19.6%
3.24M▲ 2.8%
8.97M▲ 176.7%
6.72M▼ 25.0%
6.95M▲ 3.4%
27.3M▲ 0%
Asset Turnover
0.15x0.13x0.23x0.01x1.10x0.15x0.35x0.01x-0.01x
Asset Growth %
198.82%10.8%-30.26%-47.26%-19.64%2.76%176.7%-25.02%3.38%359.4%
Total Current Liabilities
1.31M2.44M3.3M5.36M8.97M10.08M1.41M2.37M3.56M6.34M
Accounts Payable
75K150K420K761K193K568K580K744K1.93M2.83M
Days Payables Outstanding
39.9665.1153.53216.8318.55-2.35K1.4K-24.68K
Short-Term Debt
00428K2.4M7.14M7.65M0000
Deferred Revenue (Current)
180K317K283K275K000000
Other Current Liabilities
1.06M1.97M2.17M1.93M1.63M1.67M250K1.06M1.63M2.64M
Current Ratio
5.79x3.22x1.23x0.43x0.25x0.24x5.39x2.40x1.71x4.18x
Quick Ratio
5.79x3.22x1.23x0.43x0.25x0.24x5.39x2.40x1.71x4.18x
Cash Conversion Cycle
----------
Total Non-Current Liabilities
001.53M3.96M6.06M10.48M39.85M3.85M3.42M3.33M
Long-Term Debt
001.53M3.9M6.06M10.48M2.98M0196K3.01M
Capital Lease Obligations
000000462K268K0688K
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
00000036.4M3.58M3.23M162K
Total Liabilities
1.31M2.44M4.83M9.32M15.03M20.56M41.26M6.22M6.99M9.67M
Total Debt
001.96M6.3M13.2M18.12M3.44M268K196K3.17M
Net Debt
-7.38M-6.71M-396K5.77M12.62M17.48M-4.17M-3.4M-2.86M-21.36M
Debt / Equity
--0.75x----0.53x-0.18x
Debt / EBITDA
----------0.13x
Net Debt / EBITDA
---------0.88x
Interest Coverage
-701.42x---24.74x-407.76x-167.92x10.44x-20.31x-89.13x-851.75x
Total Equity
8.32M▲ 0%
8.23M▼ 1.1%
2.62M▼ 68.2%
-5.4M▼ 306.2%
-11.88M▼ 120.1%
-17.32M▼ 45.8%
-32.29M▼ 86.5%
508K▲ 101.6%
-37K▼ 107.3%
17.63M▲ 0%
Equity Growth %
137.18%-1.06%-68.21%-306.19%-120.07%-45.81%-86.51%101.57%-107.28%1145.01%
Book Value per Share
8.178.292.47-5.04-11.02-16.05-3.840.07-0.001.46
Total Shareholders' Equity
7.28M7.45M2.22M-5.12M-11.83M-17.21M4.11M641K-37K17.63M
Common Stock
3K4K4K4K4K4K01K1K1K
Retained Earnings
-66.55M-74.05M-86.21M-97.07M-105.75M-116.21M-33.18M-44.32M-63.5M-70.4M
Treasury Stock
0000000000
Accumulated OCI
68K-2K69K143K0000-14K-8K
Minority Interest
1.04M784K399K-280K-43K-103K0-133K00

SER Cash Flow Statement

Serina Therapeutics, Inc. (SER) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-6.29M-8M-10.16M-7.82M-2.25M-2.08M-2.48M-17.14M-17.95M-18.2M
Operating CF Margin %
-447.65%-572.71%-587.96%-14475.93%-64.96%-415.12%-78.53%-30601.79%--
Operating CF Growth %
25.42%-27.21%-27.08%23.06%71.21%7.78%-19.29%-592.12%-4.77%-13.96%
Net Income
-6.58M-7.5M-12.15M-10.39M-1.26M-2.68M5.27M-11.21M-19.44M-21.27M
Depreciation & Amortization
682K535K951K1.25M33.37K61.27K90K194K73K75K
Stock-Based Compensation
000082.94K7.11K25K2.6M3.79M2.92M
Deferred Taxes
0000000000
Other Non-Cash Items
-1.16M-1.24M1.45M1.58M-347.59K550.04K-7.94M-5.4M-3.85M-1.43M
Working Capital Changes
776K211K-410K-260K-754.79K-11.94K81K-3.32M1.47M1.52M
Change in Receivables
322K-24K-232K-30K1.27M1.11K065K00
Change in Inventory
0000000000
Change in Payables
267K648K169K382K-367.29K-2.13K393K-1.66M1.2M1.65M
Cash from Investing
5K1.33M-361K-20K823.32K980.94K-504K-22K-59K-84K
Capital Expenditures
-1K-1.89M-641K-20K-108.43K-9.68K-504K-22K-59K-84K
CapEx % of Revenue
0.07%135.6%37.09%37.04%3.13%1.94%15.98%39.29%-64.62%
Acquisitions
0000000000
Investments
----------
Other Investing
6K5K-74K0000000
Cash from Financing
13.28M6M6.26M5.96M1.08M1.31M10.07M13.21M17.41M38.55M
Debt Issued (Net)
001.76M5.96M-12.91K1.31M10.05M2.88M4.91M4.91M
Equity Issued (Net)
11.97M6M4.5M090.15K4.42K15K5M12.5M33.64M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
1.3M0001M005.34M00
Net Change in Cash
7.12M▲ 0%
-668K▼ 109.4%
-4.36M▼ 551.9%
-1.82M▲ 58.1%
-350.21K▲ 80.8%
217.38K▲ 162.1%
7.09M▲ 3160.1%
-3.95M▼ 155.7%
-616K▲ 84.4%
20.26M▲ 0%
Free Cash Flow
-6.29M▲ 0%
-9.89M▼ 57.3%
-10.8M▼ 9.2%
-7.84M▲ 27.4%
-2.36M▲ 69.9%
-2.09M▲ 11.6%
-2.98M▼ 42.9%
-17.16M▼ 475.8%
-17.95M▼ 4.6%
-18.24M▲ 0%
FCF Margin %
-447.72%-708.31%-625.06%-14512.96%-68.09%-417.06%-94.51%-30641.07%--14030%
FCF Growth %
25.61%-57.3%-9.23%27.44%69.9%11.61%-42.9%-475.81%-4.64%8.3%
FCF per Share
-6.17-9.96-10.19-7.32-2.19-1.93-0.35-2.33-1.76-1.51
FCF Conversion (FCF/Net Income)
0.96x1.07x0.84x0.72x1.78x0.77x-0.47x1.54x0.94x0.86x
Interest Paid
00003.09K15.88K0000
Taxes Paid
0000000000

SER Key Ratios

Serina Therapeutics, Inc. (SER) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-79.1%-90.66%-224.08%-----2193.11%-8145.22%-408.37%
Return on Invested Capital (ROIC)
--634.83%-503.03%-601.79%-219.29%-375.47%---625.86%
Gross Margin
51.21%39.76%42.22%-2272.22%-9.64%100%97.15%-246.43%-73.85%
Net Margin
-468.66%-537.39%-703.36%-20120.37%-36.5%-536.42%167.11%-19894.64%--16359.23%
Debt / Equity
--0.75x----0.53x-0.18x
Interest Coverage
-701.42x---24.74x-407.76x-167.92x10.44x-20.31x-89.13x-851.75x
FCF Conversion
0.96x1.07x0.84x0.72x1.78x0.77x-0.47x1.54x0.94x0.86x
Revenue Growth
-15.73%-0.57%23.78%-96.88%6316.21%-85.57%530.6%-98.22%-100%-
Related:SER Dividend History·SER Revenue History·SER Price History·SER P/E History·SER Financial Ratios·SER Institutional Holders

SER SEC Filings & Documents

Serina Therapeutics, Inc. (SER) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 14, 2026·SEC

Material company update

Apr 21, 2026·SEC

Material company update

Mar 25, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 25, 2026·SEC

FY 2025

Mar 24, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 11, 2025·SEC

SER Frequently Asked Questions

Serina Therapeutics, Inc. (SER) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Serina Therapeutics, Inc. (SER) reported $0.1M in revenue for fiscal year 2025. This represents a 92% decrease from $1.7M in 2016.

Serina Therapeutics, Inc. (SER) saw revenue decline by 100.0% over the past year.

Serina Therapeutics, Inc. (SER) reported a net loss of $21.3M for fiscal year 2025.

Dividend & Returns

Serina Therapeutics, Inc. (SER) has a return on equity (ROE) of -8145.2%. Negative ROE indicates the company is unprofitable.

Serina Therapeutics, Inc. (SER) had negative free cash flow of $18.2M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in SER back in 2016?

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