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TENX vs ABBV vs MRK vs PFE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TENX
Tenax Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$69M
5Y Perf.-99.5%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$358.42B
5Y Perf.+118.7%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+45.9%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$150.63B
5Y Perf.-26.9%

TENX vs ABBV vs MRK vs PFE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TENX logoTENX
ABBV logoABBV
MRK logoMRK
PFE logoPFE
IndustryBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$69M$358.42B$277.34B$150.63B
Revenue (TTM)$0.00$61.16B$64.93B$63.31B
Net Income (TTM)$-43M$4.23B$18.25B$7.49B
Gross Margin70.2%74.2%69.3%
Operating Margin26.7%41.1%23.4%
Forward P/E14.3x21.9x8.9x
Total Debt$0.00$69.07B$50.53B$67.42B
Cash & Equiv.$95M$5.23B$14.56B$1.14B

TENX vs ABBV vs MRK vs PFELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TENX
ABBV
MRK
PFE
StockMay 20May 26Return
Tenax Therapeutics,… (TENX)1000.5-99.5%
AbbVie Inc. (ABBV)100218.7+118.7%
Merck & Co., Inc. (MRK)100145.9+45.9%
Pfizer Inc. (PFE)10073.1-26.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: TENX vs ABBV vs MRK vs PFE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TENX and MRK are tied at the top with 2 categories each — the right choice depends on your priorities. Merck & Co., Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. PFE and ABBV also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
TENX
Tenax Therapeutics, Inc.
The Growth Leader

TENX has the current edge in this matchup, primarily because of its strength in growth and momentum.

  • 428.0% revenue growth vs PFE's -1.6%
  • +109.2% vs ABBV's +11.3%
Best for: growth and momentum
ABBV
AbbVie Inc.
The Growth Play

ABBV is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
  • 295.5% 10Y total return vs MRK's 166.5%
  • Beta 0.34, yield 3.2%, current ratio 0.67x
  • Beta 0.34 vs TENX's 0.90
Best for: growth exposure and long-term compounding
MRK
Merck & Co., Inc.
The Defensive Pick

MRK is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.

  • Lower volatility, beta 0.48, Low D/E 96.0%, current ratio 1.54x
  • 28.1% margin vs TENX's 2.0%
  • 14.6% ROA vs TENX's -42.1%
Best for: sleep-well-at-night
PFE
Pfizer Inc.
The Income Pick

PFE is the clearest fit if your priority is income & stability.

  • Dividend streak 15 yrs, beta 0.54, yield 6.5%
  • Lower P/E (8.9x vs 21.9x)
  • 6.5% yield, 15-year raise streak, vs ABBV's 3.2%, (1 stock pays no dividend)
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthTENX logoTENX428.0% revenue growth vs PFE's -1.6%
ValuePFE logoPFELower P/E (8.9x vs 21.9x)
Quality / MarginsMRK logoMRK28.1% margin vs TENX's 2.0%
Stability / SafetyABBV logoABBVBeta 0.34 vs TENX's 0.90
DividendsPFE logoPFE6.5% yield, 15-year raise streak, vs ABBV's 3.2%, (1 stock pays no dividend)
Momentum (1Y)TENX logoTENX+109.2% vs ABBV's +11.3%
Efficiency (ROA)MRK logoMRK14.6% ROA vs TENX's -42.1%

TENX vs ABBV vs MRK vs PFE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TENXTenax Therapeutics, Inc.
FY 2013
United States
100.0%$46,016
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B

TENX vs ABBV vs MRK vs PFE — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLPFELAGGINGTENX

Income & Cash Flow (Last 12 Months)

Evenly matched — ABBV and MRK each lead in 3 of 6 comparable metrics.

MRK and TENX operate at a comparable scale, with $64.9B and $0 in trailing revenue. MRK is the more profitable business, keeping 28.1% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, ABBV holds the edge at +10.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTENX logoTENXTenax Therapeutic…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
RevenueTrailing 12 months$0$61.2B$64.9B$63.3B
EBITDAEarnings before interest/tax-$43M$24.5B$32.4B$21.0B
Net IncomeAfter-tax profit-$43M$4.2B$18.3B$7.5B
Free Cash FlowCash after capex-$26M$18.7B$12.4B$9.5B
Gross MarginGross profit ÷ Revenue+70.2%+74.2%+69.3%
Operating MarginEBIT ÷ Revenue+26.7%+41.1%+23.4%
Net MarginNet income ÷ Revenue+6.9%+28.1%+11.8%
FCF MarginFCF ÷ Revenue+30.6%+19.0%+15.0%
Rev. Growth (YoY)Latest quarter vs prior year+10.0%+4.5%+5.4%
EPS Growth (YoY)Latest quarter vs prior year-110.5%+57.4%-19.6%-9.5%
Evenly matched — ABBV and MRK each lead in 3 of 6 comparable metrics.

Valuation Metrics

PFE leads this category, winning 5 of 6 comparable metrics.

At 15.4x trailing earnings, MRK trades at a 82% valuation discount to ABBV's 85.5x P/E. On an enterprise value basis, PFE's 10.7x EV/EBITDA is more attractive than ABBV's 15.0x.

MetricTENX logoTENXTenax Therapeutic…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
Market CapShares × price$69M$358.4B$277.3B$150.6B
Enterprise ValueMkt cap + debt − cash-$26M$422.3B$313.3B$216.9B
Trailing P/EPrice ÷ TTM EPS-10.13x85.50x15.42x19.47x
Forward P/EPrice ÷ next-FY EPS est.14.28x21.93x8.94x
PEG RatioP/E ÷ EPS growth rate0.73x
EV / EBITDAEnterprise value multiple14.96x10.68x10.66x
Price / SalesMarket cap ÷ Revenue5.86x4.27x2.41x
Price / BookPrice ÷ Book value/share1.93x5.35x1.74x
Price / FCFMarket cap ÷ FCF20.12x22.44x16.60x
PFE leads this category, winning 5 of 6 comparable metrics.

Profitability & Efficiency

MRK leads this category, winning 3 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-45 for TENX. PFE carries lower financial leverage with a 0.78x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), PFE scores 7/9 vs TENX's 3/9, reflecting strong financial health.

MetricTENX logoTENXTenax Therapeutic…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
ROE (TTM)Return on equity-45.0%+62.1%+36.1%+8.3%
ROA (TTM)Return on assets-42.1%+3.1%+14.6%+3.6%
ROICReturn on invested capital+23.9%+22.0%+7.5%
ROCEReturn on capital employed-39.0%+21.5%+23.8%+9.0%
Piotroski ScoreFundamental quality 0–93647
Debt / EquityFinancial leverage0.96x0.78x
Net DebtTotal debt minus cash-$95M$63.8B$36.0B$66.3B
Cash & Equiv.Liquid assets$95M$5.2B$14.6B$1.1B
Total DebtShort + long-term debt$0$69.1B$50.5B$67.4B
Interest CoverageEBIT ÷ Interest expense-847.57x3.28x19.68x4.02x
MRK leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ABBV leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $35 for TENX. Over the past 12 months, TENX leads with a +109.2% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs TENX's -23.4% — a key indicator of consistent wealth creation.

MetricTENX logoTENXTenax Therapeutic…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
YTD ReturnYear-to-date+5.4%-10.1%+6.3%+6.9%
1-Year ReturnPast 12 months+109.2%+11.3%+46.1%+23.7%
3-Year ReturnCumulative with dividends-55.1%+50.4%+2.9%-18.4%
5-Year ReturnCumulative with dividends-99.6%+101.3%+70.2%-13.3%
10-Year ReturnCumulative with dividends-100.0%+295.5%+166.5%+29.6%
CAGR (3Y)Annualised 3-year return-23.4%+14.6%+0.9%-6.6%
ABBV leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ABBV and PFE each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than TENX's 0.90 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 92.1% from its 52-week high vs TENX's 63.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTENX logoTENXTenax Therapeutic…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
Beta (5Y)Sensitivity to S&P 5000.90x0.34x0.48x0.54x
52-Week HighHighest price in past year$18.38$244.81$125.14$28.75
52-Week LowLowest price in past year$5.34$176.57$73.31$21.97
% of 52W HighCurrent price vs 52-week peak+63.4%+82.8%+89.7%+92.1%
RSI (14)Momentum oscillator 0–10038.446.846.744.2
Avg Volume (50D)Average daily shares traded520K5.8M7.3M33.3M
Evenly matched — ABBV and PFE each lead in 1 of 2 comparable metrics.

Analyst Outlook

PFE leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: ABBV as "Buy", MRK as "Buy", PFE as "Hold". Consensus price targets imply 26.6% upside for ABBV (target: $257) vs 3.0% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.49% vs MRK's 2.90%.

MetricTENX logoTENXTenax Therapeutic…ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyHold
Price TargetConsensus 12-month target$256.64$129.31$27.27
# AnalystsCovering analysts413739
Dividend YieldAnnual dividend ÷ price+3.2%+2.9%+6.5%
Dividend StreakConsecutive years of raises1131415
Dividend / ShareAnnual DPS$6.57$3.26$1.72
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.3%+1.8%0.0%
PFE leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

PFE leads in 2 of 6 categories (Valuation Metrics, Analyst Outlook). MRK leads in 1 (Profitability & Efficiency). 2 tied.

Best OverallPfizer Inc. (PFE)Leads 2 of 6 categories
Loading custom metrics...

TENX vs ABBV vs MRK vs PFE: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is TENX or ABBV or MRK or PFE a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 4x trailing P/E (21. 9x forward), making it the more compelling value choice. Analysts rate AbbVie Inc. (ABBV) a "Buy" — based on 41 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — TENX or ABBV or MRK or PFE?

On trailing P/E, Merck & Co.

, Inc. (MRK) is the cheapest at 15. 4x versus AbbVie Inc. at 85. 5x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — TENX or ABBV or MRK or PFE?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +101. 3%, compared to -99. 6% for Tenax Therapeutics, Inc. (TENX). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus TENX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — TENX or ABBV or MRK or PFE?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 34β versus Tenax Therapeutics, Inc. 's 0. 90β — meaning TENX is approximately 166% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Pfizer Inc. (PFE) carries a lower debt/equity ratio of 78% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — TENX or ABBV or MRK or PFE?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Tenax Therapeutics, Inc. grew EPS 96. 3% year-over-year, compared to -3. 5% for Pfizer Inc.. Over a 3-year CAGR, MRK leads at 3. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — TENX or ABBV or MRK or PFE?

Merck & Co.

, Inc. (MRK) is the more profitable company, earning 28. 1% net margin versus 0. 0% for Tenax Therapeutics, Inc. — meaning it keeps 28. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus 0. 0% for TENX. At the gross margin level — before operating expenses — MRK leads at 72. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is TENX or ABBV or MRK or PFE more undervalued right now?

On forward earnings alone, Pfizer Inc.

(PFE) trades at 8. 9x forward P/E versus 21. 9x for Merck & Co. , Inc. — 13. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ABBV: 26. 6% to $256. 64.

08

Which pays a better dividend — TENX or ABBV or MRK or PFE?

In this comparison, PFE (6.

5% yield), ABBV (3. 2% yield), MRK (2. 9% yield) pay a dividend. TENX does not pay a meaningful dividend and should not be held primarily for income.

09

Is TENX or ABBV or MRK or PFE better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, TENX: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between TENX and ABBV and MRK and PFE?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TENX is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; MRK is a large-cap deep-value stock; PFE is a mid-cap income-oriented stock. ABBV, MRK, PFE pay a dividend while TENX does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 16%
  • Dividend Yield > 1.1%
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PFE

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  • Market Cap > $100B
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