Biotechnology
Compare Stocks
4 / 10Stock Comparison
TLX vs NVS vs BMY vs PFE
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Drug Manufacturers - General
TLX vs NVS vs BMY vs PFE — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $3.57B | $278.64B | $114.66B | $146.02B |
| Revenue (TTM) | $1.66B | $56.05B | $48.48B | $63.31B |
| Net Income (TTM) | $66M | $13.53B | $7.28B | $7.49B |
| Gross Margin | 61.6% | 75.3% | 68.7% | 69.3% |
| Operating Margin | 7.1% | 30.5% | 25.7% | 23.4% |
| Forward P/E | 167.1x | 16.7x | 8.9x | 8.7x |
| Total Debt | $581M | $37.03B | $47.14B | $67.42B |
| Cash & Equiv. | $710M | $11.44B | $10.21B | $1.14B |
TLX vs NVS vs BMY vs PFE — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Nov 24 | May 26 | Return |
|---|---|---|---|
| Telix Pharmaceutica… (TLX) | 100 | 64.8 | -35.2% |
| Novartis AG (NVS) | 100 | 138.1 | +38.1% |
| Bristol-Myers Squib… (BMY) | 100 | 94.8 | -5.2% |
| Pfizer Inc. (PFE) | 100 | 97.9 | -2.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TLX vs NVS vs BMY vs PFE
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TLX is the clearest fit if your priority is growth exposure.
- Rev growth 55.8%, EPS growth 7.7%, 3Y rev CAGR 368.9%
- 55.8% revenue growth vs PFE's -1.6%
NVS carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.
- 179.4% 10Y total return vs PFE's 28.5%
- Lower volatility, beta 0.42, Low D/E 79.6%, current ratio 1.12x
- 24.1% margin vs TLX's 4.0%
- Beta 0.42 vs TLX's 0.88, lower leverage
BMY is the clearest fit if your priority is defensive.
- Beta 0.45, yield 4.4%, current ratio 1.26x
PFE is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 15 yrs, beta 0.49, yield 6.7%
- Lower P/E (8.7x vs 16.7x)
- 6.7% yield, 15-year raise streak, vs BMY's 4.4%, (1 stock pays no dividend)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 55.8% revenue growth vs PFE's -1.6% | |
| Value | Lower P/E (8.7x vs 16.7x) | |
| Quality / Margins | 24.1% margin vs TLX's 4.0% | |
| Stability / Safety | Beta 0.42 vs TLX's 0.88, lower leverage | |
| Dividends | 6.7% yield, 15-year raise streak, vs BMY's 4.4%, (1 stock pays no dividend) | |
| Momentum (1Y) | +36.9% vs TLX's -37.4% | |
| Efficiency (ROA) | 12.1% ROA vs PFE's 3.6%, ROIC 18.8% vs 7.5% |
TLX vs NVS vs BMY vs PFE — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
TLX vs NVS vs BMY vs PFE — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NVS leads in 2 of 6 categories
PFE leads 1 • TLX leads 0 • BMY leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NVS leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PFE is the larger business by revenue, generating $63.3B annually — 38.2x TLX's $1.7B. NVS is the more profitable business, keeping 24.1% of every revenue dollar as net income compared to TLX's 4.0%.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $1.7B | $56.1B | $48.5B | $63.3B |
| EBITDAEarnings before interest/tax | $132M | $22.5B | $15.7B | $21.0B |
| Net IncomeAfter-tax profit | $66M | $13.5B | $7.3B | $7.5B |
| Free Cash FlowCash after capex | $45M | $16.4B | $11.9B | $9.5B |
| Gross MarginGross profit ÷ Revenue | +61.6% | +75.3% | +68.7% | +69.3% |
| Operating MarginEBIT ÷ Revenue | +7.1% | +30.5% | +25.7% | +23.4% |
| Net MarginNet income ÷ Revenue | +4.0% | +24.1% | +15.0% | +11.8% |
| FCF MarginFCF ÷ Revenue | +2.7% | +29.2% | +24.6% | +15.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +2.1% | -0.7% | +2.6% | +5.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -130.9% | -9.3% | +9.2% | -9.5% |
Valuation Metrics
Evenly matched — BMY and PFE each lead in 3 of 6 comparable metrics.
Valuation Metrics
At 16.3x trailing earnings, BMY trades at a 85% valuation discount to TLX's 105.7x P/E. On an enterprise value basis, BMY's 9.2x EV/EBITDA is more attractive than TLX's 54.9x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $3.6B | $278.6B | $114.7B | $146.0B |
| Enterprise ValueMkt cap + debt − cash | $3.5B | $304.2B | $151.6B | $212.3B |
| Trailing P/EPrice ÷ TTM EPS | 105.68x | 20.31x | 16.28x | 18.88x |
| Forward P/EPrice ÷ next-FY EPS est. | 167.14x | 16.68x | 8.91x | 8.66x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.32x | — | — |
| EV / EBITDAEnterprise value multiple | 54.93x | 13.57x | 9.16x | 10.44x |
| Price / SalesMarket cap ÷ Revenue | 6.32x | 5.08x | 2.38x | 2.33x |
| Price / BookPrice ÷ Book value/share | 8.99x | 6.13x | 6.19x | 1.68x |
| Price / FCFMarket cap ÷ FCF | 172.51x | 15.75x | 8.93x | 16.09x |
Profitability & Efficiency
Evenly matched — TLX and NVS each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
BMY delivers a 39.0% return on equity — every $100 of shareholder capital generates $39 in annual profit, vs $8 for PFE. PFE carries lower financial leverage with a 0.78x debt-to-equity ratio, signaling a more conservative balance sheet compared to BMY's 2.55x. On the Piotroski fundamental quality scale (0–9), BMY scores 8/9 vs TLX's 5/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +15.6% | +31.4% | +39.0% | +8.3% |
| ROA (TTM)Return on assets | +5.5% | +12.1% | +7.9% | +3.6% |
| ROICReturn on invested capital | +25.5% | +18.8% | +16.9% | +7.5% |
| ROCEReturn on capital employed | +11.5% | +21.1% | +18.7% | +9.0% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 6 | 8 | 7 |
| Debt / EquityFinancial leverage | 1.02x | 0.80x | 2.55x | 0.78x |
| Net DebtTotal debt minus cash | -$129M | $25.6B | $36.9B | $66.3B |
| Cash & Equiv.Liquid assets | $710M | $11.4B | $10.2B | $1.1B |
| Total DebtShort + long-term debt | $581M | $37.0B | $47.1B | $67.4B |
| Interest CoverageEBIT ÷ Interest expense | 4.31x | 13.92x | 10.33x | 4.02x |
Total Returns (Dividends Reinvested)
NVS leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NVS five years ago would be worth $19,507 today (with dividends reinvested), compared to $7,050 for TLX. Over the past 12 months, NVS leads with a +36.9% total return vs TLX's -37.4%. The 3-year compound annual growth rate (CAGR) favors NVS at 16.7% vs TLX's -11.0% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +40.2% | +8.8% | +7.4% | +5.4% |
| 1-Year ReturnPast 12 months | -37.4% | +36.9% | +25.1% | +21.1% |
| 3-Year ReturnCumulative with dividends | -29.5% | +59.1% | -7.3% | -19.4% |
| 5-Year ReturnCumulative with dividends | -29.5% | +95.1% | +4.7% | -14.8% |
| 10-Year ReturnCumulative with dividends | -29.5% | +179.4% | +6.6% | +28.5% |
| CAGR (3Y)Annualised 3-year return | -11.0% | +16.7% | -2.5% | -6.9% |
Risk & Volatility
Evenly matched — NVS and PFE each lead in 1 of 2 comparable metrics.
Risk & Volatility
NVS is the less volatile stock with a 0.42 beta — it tends to amplify market swings less than TLX's 0.88 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 89.3% from its 52-week high vs TLX's 57.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.88x | 0.42x | 0.45x | 0.49x |
| 52-Week HighHighest price in past year | $18.49 | $170.46 | $62.89 | $28.75 |
| 52-Week LowLowest price in past year | $6.30 | $104.93 | $42.52 | $21.97 |
| % of 52W HighCurrent price vs 52-week peak | +57.8% | +85.7% | +89.3% | +89.3% |
| RSI (14)Momentum oscillator 0–100 | 56.3 | 43.3 | 40.4 | 43.9 |
| Avg Volume (50D)Average daily shares traded | 230K | 1.9M | 10.2M | 33.3M |
Analyst Outlook
PFE leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: TLX as "Buy", NVS as "Hold", BMY as "Hold", PFE as "Hold". Consensus price targets imply 59.2% upside for TLX (target: $17) vs -3.4% for NVS (target: $141). For income investors, PFE offers the higher dividend yield at 6.69% vs NVS's 2.75%.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Hold | Hold | Hold |
| Price TargetConsensus 12-month target | $17.00 | $141.00 | $62.00 | $27.40 |
| # AnalystsCovering analysts | 5 | 25 | 41 | 39 |
| Dividend YieldAnnual dividend ÷ price | — | +2.8% | +4.4% | +6.7% |
| Dividend StreakConsecutive years of raises | 1 | 6 | 6 | 15 |
| Dividend / ShareAnnual DPS | — | $4.02 | $2.47 | $1.72 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +3.3% | 0.0% | 0.0% |
NVS leads in 2 of 6 categories (Income & Cash Flow, Total Returns). PFE leads in 1 (Analyst Outlook). 3 tied.
TLX vs NVS vs BMY vs PFE: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TLX or NVS or BMY or PFE a better buy right now?
For growth investors, Telix Pharmaceuticals Limited (TLX) is the stronger pick with 55.
8% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Bristol-Myers Squibb Company (BMY) offers the better valuation at 16. 3x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate Telix Pharmaceuticals Limited (TLX) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TLX or NVS or BMY or PFE?
On trailing P/E, Bristol-Myers Squibb Company (BMY) is the cheapest at 16.
3x versus Telix Pharmaceuticals Limited at 105. 7x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 7x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — TLX or NVS or BMY or PFE?
Over the past 5 years, Novartis AG (NVS) delivered a total return of +95.
1%, compared to -29. 5% for Telix Pharmaceuticals Limited (TLX). Over 10 years, the gap is even starker: NVS returned +179. 4% versus TLX's -29. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TLX or NVS or BMY or PFE?
By beta (market sensitivity over 5 years), Novartis AG (NVS) is the lower-risk stock at 0.
42β versus Telix Pharmaceuticals Limited's 0. 88β — meaning TLX is approximately 111% more volatile than NVS relative to the S&P 500. On balance sheet safety, Pfizer Inc. (PFE) carries a lower debt/equity ratio of 78% versus 3% for Bristol-Myers Squibb Company — giving it more financial flexibility in a downturn.
05Which is growing faster — TLX or NVS or BMY or PFE?
By revenue growth (latest reported year), Telix Pharmaceuticals Limited (TLX) is pulling ahead at 55.
8% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Telix Pharmaceuticals Limited grew EPS 769. 6% year-over-year, compared to -3. 5% for Pfizer Inc.. Over a 3-year CAGR, TLX leads at 368. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TLX or NVS or BMY or PFE?
Novartis AG (NVS) is the more profitable company, earning 25.
6% net margin versus 6. 4% for Telix Pharmaceuticals Limited — meaning it keeps 25. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVS leads at 31. 2% versus 10. 5% for TLX. At the gross margin level — before operating expenses — NVS leads at 75. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TLX or NVS or BMY or PFE more undervalued right now?
On forward earnings alone, Pfizer Inc.
(PFE) trades at 8. 7x forward P/E versus 167. 1x for Telix Pharmaceuticals Limited — 158. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for TLX: 59. 2% to $17. 00.
08Which pays a better dividend — TLX or NVS or BMY or PFE?
In this comparison, PFE (6.
7% yield), BMY (4. 4% yield), NVS (2. 8% yield) pay a dividend. TLX does not pay a meaningful dividend and should not be held primarily for income.
09Is TLX or NVS or BMY or PFE better for a retirement portfolio?
For long-horizon retirement investors, Novartis AG (NVS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
42), 2. 8% yield, +179. 4% 10Y return). Both have compounded well over 10 years (NVS: +179. 4%, TLX: -29. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TLX and NVS and BMY and PFE?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: TLX is a small-cap high-growth stock; NVS is a large-cap quality compounder stock; BMY is a mid-cap deep-value stock; PFE is a mid-cap income-oriented stock. NVS, BMY, PFE pay a dividend while TLX does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.