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ANL
ZLAB logo
ZLAB
ZYME logo
ZYME
CAN logo
CAN
IMVT logo
IMVT
JPM logo
JPM
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Stock Comparison

ANL vs ZLAB vs ZYME vs CAN vs IMVT vs JPM

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ANL
Adlai Nortye Ltd.

Biotechnology

HealthcareNASDAQ • KY
Market Cap$322M
5Y Perf.-31.2%
ZLAB
Zai Lab Limited

Biotechnology

HealthcareNASDAQ • CN
Market Cap$1.89B
5Y Perf.-29.8%
ZYME
Zymeworks Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$1.68B
5Y Perf.+260.9%
CAN
Canaan Inc.

Computer Hardware

TechnologyNASDAQ • SG
Market Cap$203M
5Y Perf.-82.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.-12.4%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$896.00B
5Y Perf.+121.2%

ANL vs ZLAB vs ZYME vs CAN vs IMVT vs JPM — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ANL logoANL
ZLAB logoZLAB
ZYME logoZYME
CAN logoCAN
IMVT logoIMVT
JPM logoJPM
IndustryBiotechnologyBiotechnologyBiotechnologyComputer HardwareBiotechnologyBanks - Diversified
Market Cap$322M$1.89B$1.68B$203M$6.90B$896.00B
Revenue (TTM)$6M$453M$81M$530M$0.00$280.33B
Net Income (TTM)$-54M$-178M$-103M$-210M$-506M$57.05B
Gross Margin100.0%57.9%94.4%7.8%60.0%
Operating Margin-10.0%-53.5%-140.4%-19.3%25.9%
Forward P/E15.5x14.4x
Total Debt$27M$224M$18M$55M$72K$942.38B
Cash & Equiv.$61M$680M$41M$81M$902M$343.34B

ANL vs ZLAB vs ZYME vs CAN vs IMVT vs JPMLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ANL
ZLAB
ZYME
CAN
IMVT
JPM
StockSep 23Jun 26Return
Adlai Nortye Ltd. (ANL)10068.8-31.2%
Zai Lab Limited (ZLAB)10070.2-29.8%
Zymeworks Inc. (ZYME)100360.9+260.9%
Canaan Inc. (CAN)10017.6-82.4%
Immunovant, Inc. (IMVT)10087.6-12.4%
JPMorgan Chase & Co. (JPM)100221.2+121.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: ANL vs ZLAB vs ZYME vs CAN vs IMVT vs JPM

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JPM leads in 4 of 7 categories (6-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Adlai Nortye Ltd. is the stronger pick specifically for recent price momentum and sentiment. ZYME and CAN also each lead in at least one category. This set spans 3 sectors — these stocks serve different portfolio roles, not just different price points.
🥇JPM emerged as the overall leader. Track its performance:
ANL
Adlai Nortye Ltd.
The Momentum Pick

ANL is the #2 pick in this set and the best alternative if momentum is your priority.

  • +5.5% vs ZLAB's -60.3%
Best for: momentum
ZLAB
Zai Lab Limited
The Healthcare Pick

Among these 6 stocks, ZLAB doesn't own a clear edge in any measured category.

Best for: healthcare exposure
ZYME
Zymeworks Inc.
The Defensive Pick

ZYME ranks third and is worth considering specifically for sleep-well-at-night and defensive.

  • Lower volatility, beta 0.87, Low D/E 6.8%, current ratio 5.52x
  • Beta 0.87, current ratio 5.52x
  • Beta 0.87 vs CAN's 4.24, lower leverage
Best for: sleep-well-at-night and defensive
CAN
Canaan Inc.
The Growth Play

CAN is the clearest fit if your priority is growth exposure.

  • Rev growth 96.7%, EPS growth 51.1%, 3Y rev CAGR -6.7%
  • 96.7% revenue growth vs ANL's -100.0%
Best for: growth exposure
IMVT
Immunovant, Inc.
The Healthcare Pick

IMVT doesn't hold a clear category lead here; it's more of a secondary option in this specific comparison.

Best for: healthcare exposure
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 15 yrs, beta 0.94, yield 1.9%
  • 465.8% 10Y total return vs IMVT's 237.9%
  • Better valuation composite
  • 20.4% margin vs ANL's -8.3%
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthCAN logoCAN96.7% revenue growth vs ANL's -100.0%
ValueJPM logoJPMBetter valuation composite
Quality / MarginsJPM logoJPM20.4% margin vs ANL's -8.3%
Stability / SafetyZYME logoZYMEBeta 0.87 vs CAN's 4.24, lower leverage
DividendsJPM logoJPM1.9% yield; 15-year raise streak; the other 5 pay no meaningful dividend
Momentum (1Y)ANL logoANL+5.5% vs ZLAB's -60.3%
Efficiency (ROA)JPM logoJPM1.3% ROA vs IMVT's -62.2%

ANL vs ZLAB vs ZYME vs CAN vs IMVT vs JPM — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ANLAdlai Nortye Ltd.

Segment breakdown not available.

ZLABZai Lab Limited
FY 2025
Zejula
56.5%$189M
Nuzyra
18.2%$61M
Optune
14.4%$48M
Qinlock
10.6%$36M
Product and Service, Other
0.2%$717,000
ZYMEZymeworks Inc.
FY 2025
Milestone Revenue
61.6%$25M
Option Exercise Fee
18.5%$8M
Research Support Payments And Other Service
13.8%$6M
Royalty
6.1%$2M
CANCanaan Inc.
FY 2025
Product
78.5%$414M
Mining
21.5%$113M
IMVTImmunovant, Inc.

Segment breakdown not available.

JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000

ANL vs ZLAB vs ZYME vs CAN vs IMVT vs JPM — Financial Metrics

Side-by-side numbers across 6 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJPMLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

JPM leads this category, winning 3 of 6 comparable metrics.

JPM and IMVT operate at a comparable scale, with $280.3B and $0 in trailing revenue. JPM is the more profitable business, keeping 20.4% of every revenue dollar as net income compared to ANL's -8.3%. On growth, CAN holds the edge at +121.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.JPM logoJPMJPMorgan Chase & …
RevenueTrailing 12 months$6M$453M$81M$530M$0$280.3B
EBITDAEarnings before interest/tax-$64M-$227M-$118M-$140M-$532M$81.4B
Net IncomeAfter-tax profit-$54M-$178M-$103M-$210M-$506M$57.0B
Free Cash FlowCash after capex-$67M-$129M-$45.7B$0-$407M$100.9B
Gross MarginGross profit ÷ Revenue+100.0%+57.9%+94.4%+7.8%+60.0%
Operating MarginEBIT ÷ Revenue-10.0%-53.5%-140.4%-19.3%+25.9%
Net MarginNet income ÷ Revenue-8.3%-39.3%-126.3%-39.7%+20.4%
FCF MarginFCF ÷ Revenue-10.3%-28.5%-563.0%+36.0%
Rev. Growth (YoY)Latest quarter vs prior year-6.5%-91.1%+121.1%
EPS Growth (YoY)Latest quarter vs prior year+78.7%-11.1%-96.7%+59.4%-14.1%+16.0%
JPM leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

CAN leads this category, winning 2 of 4 comparable metrics.
MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.JPM logoJPMJPMorgan Chase & …
Market CapShares × price$322M$1.9B$1.7B$203M$6.9B$896.0B
Enterprise ValueMkt cap + debt − cash$289M$1.4B$1.7B$177M$6.0B$1.50T
Trailing P/EPrice ÷ TTM EPS-2.11x-10.67x-21.19x-0.71x-12.14x16.00x
Forward P/EPrice ÷ next-FY EPS est.15.46x14.40x
PEG RatioP/E ÷ EPS growth rate0.90x
EV / EBITDAEnterprise value multiple18.36x
Price / SalesMarket cap ÷ Revenue4.11x15.89x0.38x3.20x
Price / BookPrice ÷ Book value/share4.31x2.61x6.42x0.34x7.19x2.47x
Price / FCFMarket cap ÷ FCF8.88x
CAN leads this category, winning 2 of 4 comparable metrics.

Profitability & Efficiency

JPM leads this category, winning 5 of 9 comparable metrics.

JPM delivers a 15.9% return on equity — every $100 of shareholder capital generates $16 in annual profit, vs $-101 for ANL. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), CAN scores 6/9 vs IMVT's 2/9, reflecting solid financial health.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.JPM logoJPMJPMorgan Chase & …
ROE (TTM)Return on equity-101.3%-24.3%-0.2%-60.7%-68.2%+15.9%
ROA (TTM)Return on assets-50.2%-15.5%-0.1%-34.6%-62.2%+1.3%
ROICReturn on invested capital-7.3%-41.7%-25.9%-24.9%+4.5%
ROCEReturn on capital employed-103.8%-27.2%-27.3%-29.7%-68.3%+8.9%
Piotroski ScoreFundamental quality 0–9235625
Debt / EquityFinancial leverage1.07x0.31x0.07x0.13x0.00x2.60x
Net DebtTotal debt minus cash-$34M-$455M-$23M-$26M-$902M$599.0B
Cash & Equiv.Liquid assets$61M$680M$41M$81M$902M$343.3B
Total DebtShort + long-term debt$27M$224M$18M$55M$72,000$942.4B
Interest CoverageEBIT ÷ Interest expense-28.22x-30.73x-52.03x-104.53x0.74x
JPM leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — ANL and ZYME each lead in 2 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $680 for CAN. Over the past 12 months, ANL leads with a +545.0% total return vs ZLAB's -60.3%. The 3-year compound annual growth rate (CAGR) favors ZYME at 39.9% vs CAN's -47.7% — a key indicator of consistent wealth creation.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.JPM logoJPMJPMorgan Chase & …
YTD ReturnYear-to-date+647.8%-1.5%-14.0%-58.4%+29.8%-0.5%
1-Year ReturnPast 12 months+545.0%-60.3%+74.7%-54.4%+110.9%+21.8%
3-Year ReturnCumulative with dividends-31.2%-38.2%+173.7%-85.7%+55.0%+138.2%
5-Year ReturnCumulative with dividends-31.2%-90.0%-39.7%-93.2%+213.0%+118.2%
10-Year ReturnCumulative with dividends-31.2%-38.9%+76.0%-92.2%+237.9%+465.8%
CAGR (3Y)Annualised 3-year return-11.7%-14.8%+39.9%-47.7%+15.7%+33.6%
Evenly matched — ANL and ZYME each lead in 2 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ZYME and JPM each lead in 1 of 2 comparable metrics.

ZYME is the less volatile stock with a 0.87 beta — it tends to amplify market swings less than CAN's 4.24 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. JPM currently trades 95.1% from its 52-week high vs CAN's 14.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.JPM logoJPMJPMorgan Chase & …
Beta (5Y)Sensitivity to S&P 5001.39x1.15x0.87x4.24x1.66x0.94x
52-Week HighHighest price in past year$17.25$44.34$29.75$2.22$36.27$337.25
52-Week LowLowest price in past year$0.88$15.96$11.51$0.31$14.32$262.71
% of 52W HighCurrent price vs 52-week peak+59.8%+38.5%+76.9%+14.4%+92.7%+95.1%
RSI (14)Momentum oscillator 0–10039.043.436.730.157.959.1
Avg Volume (50D)Average daily shares traded380K842K584K9.7M1.9M7.0M
Evenly matched — ZYME and JPM each lead in 1 of 2 comparable metrics.

Analyst Outlook

JPM leads this category, winning 1 of 1 comparable metric.

Analyst consensus: ANL as "Buy", ZLAB as "Buy", ZYME as "Buy", CAN as "Buy", IMVT as "Buy", JPM as "Buy". Consensus price targets imply 337.2% upside for CAN (target: $1) vs 5.9% for JPM (target: $340). JPM is the only dividend payer here at 1.86% yield — a key consideration for income-focused portfolios.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.JPM logoJPMJPMorgan Chase & …
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$26.00$35.00$40.67$1.40$43.67$339.75
# AnalystsCovering analysts1112062361
Dividend YieldAnnual dividend ÷ price+1.9%
Dividend StreakConsecutive years of raises015
Dividend / ShareAnnual DPS$5.95
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+2.5%0.0%0.0%+3.9%
JPM leads this category, winning 1 of 1 comparable metric.
Key Takeaway

JPM leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CAN leads in 1 (Valuation Metrics). 2 tied.

Best OverallJPMorgan Chase & Co. (JPM)Leads 3 of 6 categories
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ANL vs ZLAB vs ZYME vs CAN vs IMVT vs JPM: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ANL or ZLAB or ZYME or CAN or IMVT or JPM a better buy right now?

For growth investors, Canaan Inc.

(CAN) is the stronger pick with 96. 7% revenue growth year-over-year, versus -100. 0% for Adlai Nortye Ltd. (ANL). JPMorgan Chase & Co. (JPM) offers the better valuation at 16. 0x trailing P/E (14. 4x forward), making it the more compelling value choice. Analysts rate Adlai Nortye Ltd. (ANL) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ANL or ZLAB or ZYME or CAN or IMVT or JPM?

On forward P/E, JPMorgan Chase & Co.

is actually cheaper at 14. 4x.

03

Which is the better long-term investment — ANL or ZLAB or ZYME or CAN or IMVT or JPM?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +213. 0%, compared to -93. 2% for Canaan Inc. (CAN). Over 10 years, the gap is even starker: JPM returned +465. 8% versus CAN's -92. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ANL or ZLAB or ZYME or CAN or IMVT or JPM?

By beta (market sensitivity over 5 years), Zymeworks Inc.

(ZYME) is the lower-risk stock at 0. 87β versus Canaan Inc. 's 4. 24β — meaning CAN is approximately 389% more volatile than ZYME relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ANL or ZLAB or ZYME or CAN or IMVT or JPM?

By revenue growth (latest reported year), Canaan Inc.

(CAN) is pulling ahead at 96. 7% versus -100. 0% for Adlai Nortye Ltd. (ANL). On earnings-per-share growth, the picture is similar: Adlai Nortye Ltd. grew EPS 68. 3% year-over-year, compared to -1. 5% for Immunovant, Inc.. Over a 3-year CAGR, ZLAB leads at 28. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ANL or ZLAB or ZYME or CAN or IMVT or JPM?

JPMorgan Chase & Co.

(JPM) is the more profitable company, earning 20. 4% net margin versus -833. 1% for Adlai Nortye Ltd. — meaning it keeps 20. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JPM leads at 26. 0% versus -996. 4% for ANL. At the gross margin level — before operating expenses — ANL leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ANL or ZLAB or ZYME or CAN or IMVT or JPM more undervalued right now?

On forward earnings alone, JPMorgan Chase & Co.

(JPM) trades at 14. 4x forward P/E versus 15. 5x for Zymeworks Inc. — 1. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CAN: 337. 2% to $1. 40.

08

Which pays a better dividend — ANL or ZLAB or ZYME or CAN or IMVT or JPM?

In this comparison, JPM (1.

9% yield) pays a dividend. ANL, ZLAB, ZYME, CAN, IMVT do not pay a meaningful dividend and should not be held primarily for income.

09

Is ANL or ZLAB or ZYME or CAN or IMVT or JPM better for a retirement portfolio?

For long-horizon retirement investors, JPMorgan Chase & Co.

(JPM) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 94), 1. 9% yield, +465. 8% 10Y return). Canaan Inc. (CAN) carries a higher beta of 4. 24 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (JPM: +465. 8%, CAN: -92. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ANL and ZLAB and ZYME and CAN and IMVT and JPM?

These companies operate in different sectors (ANL (Healthcare) and ZLAB (Healthcare) and ZYME (Healthcare) and CAN (Technology) and IMVT (Healthcare) and JPM (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ANL is a small-cap quality compounder stock; ZLAB is a small-cap high-growth stock; ZYME is a small-cap high-growth stock; CAN is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; JPM is a large-cap deep-value stock. JPM pays a dividend while ANL, ZLAB, ZYME, CAN, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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