Agios Pharmaceuticals, Inc. (AGIO) Earnings History
Annual and quarterly earnings data from 2011 to 2025
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AGIO EPS Growth (CAGR)
Compound annual growth rate of diluted earnings per share
CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.
AGIO Profitability Analysis
Margin trends over time
| Year | Gross Margin | Operating Margin | Net Margin |
|---|---|---|---|
| 2025 | 78.7% | -873.9% | -764.0% |
| 2024 | 88.6% | -1166.5% | 1845.9% |
| 2023 | 64.6% | -1459.5% | -1312.6% |
| 2022 | 88.0% | -2732.1% | -1627.8% |
| 2021 | - | - | - |
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Agios Pharmaceuticals, Inc. (AGIO) Earnings Overview
As of May 8, 2026, Agios Pharmaceuticals, Inc. (AGIO) reported trailing twelve-month net income of -$423M, reflecting -161.2% year-over-year growth. The company earned $-7.19 per diluted share over the past four quarters, with a net profit margin of -764.0%.
Looking at the long-term picture, AGIO's historical earnings data spans multiple years. The company achieved its highest annual net income of $1.60B in fiscal 2021.
Agios Pharmaceuticals, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →
Compared to peers including IONS (-$327M net income, -40.4% margin), PTCT (-$187M net income, 39.4% margin), RARE (-$609M net income, -85.4% margin), AGIO has room to improve margins relative to the peer group. Compare AGIO vs IONS →
AGIO Earnings vs Peers
Earnings metrics vs comparable public companies
AGIO Historical Earnings Data (2011–2025)
15 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | -$413M | -161.3% | -$472M | $-7.12 | -764.0% | -873.9% |
| 2024 | $674M | +291.4% | -$426M | $11.64 | 1845.9% | -1166.5% |
| 2023 | -$352M | -51.9% | -$391M | $-6.33 | -1312.6% | -1459.5% |
| 2022 | -$232M | -114.4% | -$389M | $-4.23 | -1627.8% | -2732.1% |
| 2021 | $1.60B | +590.2% | -$378M | $-6.36 | - | - |
| 2020 | -$327M | +20.4% | -$336M | $-4.74 | - | - |
| 2019 | -$411M | -18.9% | -$426M | $-6.61 | -349.0% | -361.6% |
| 2018 | -$346M | -10.0% | -$362M | $-6.03 | -366.6% | -384.0% |
| 2017 | -$315M | -58.5% | -$321M | $-6.75 | -731.6% | -745.8% |
| 2016 | -$198M | -68.6% | -$201M | $-5.07 | -284.0% | -287.6% |
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Start ComparisonAGIO — Frequently Asked Questions
Quick answers to the most common questions about buying AGIO stock.
Is AGIO growing earnings?
AGIO EPS fell to $-7.19, with earnings declining -161.2%. This contrasts with the 5-year CAGR of N/A. TTM net income dropped to $-423M.
What are AGIO's profit margins?
Agios Pharmaceuticals, Inc. net margin is -764.0%, with operating margin at -873.9%. Below-average margins reflect competitive or cost pressures.
How consistent are AGIO's earnings?
AGIO earnings data spans 2011-2025. The declining earnings trend is -161.2% YoY. Historical data enables comparison across business cycles.