AN2 Therapeutics, Inc. (ANTX) P/E Ratio History
Insufficient DataInsufficient historical P/E data to classify valuation. · Data 2026–2026
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P/E Ratio Analysis
As of June 13, 2026, AN2 Therapeutics, Inc. (ANTX) trades at a price-to-earnings ratio of -4.1x, with a stock price of $4.74 and trailing twelve-month earnings per share of $-1.01.
Compared to the Healthcare sector median P/E of 22.9x, ANTX trades at a 118% discount to its sector peers. The sector includes 234 companies with P/E ratios ranging from 0.0x to 183.0x.
Relative to the broader market, ANTX trades at a notable discount to the S&P 500 median P/E of 25.1x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our ANTX DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
ANTX Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
ANTX P/E vs Peers
Vaccines and Infectious Disease peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $165M | 19.0Lowest | - | +112%Best | |
| $13B | 30.6 | 0.96Best | +21% | |
| $149B | 19.3 | - | -4% |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
What if you invested $1,000 in ANTX back in 2026?
Total return with dividends reinvested · 0+ years of data
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Compare NowANTX — Frequently Asked Questions
Quick answers to the most common questions about buying ANTX stock.
What is ANTX's P/E ratio?
AN2 Therapeutics, Inc. (ANTX) trailing twelve-month P/E ratio is -4.1x, based on TTM diluted EPS of $-1.01. The 5-year average P/E is N/A and the historical range spans N/A to N/A.
Is ANTX stock overvalued or undervalued?
ANTX current P/E: -4.1x. 5-year average P/E: N/A. Percentile: N/A.
Is ANTX stock expensive?
ANTX is fairly valued relative to its own history. The current P/E of -4.1x is near the 5-year average of N/A (N/A percentile of historical range).
What is ANTX's historical P/E range?
Over the past 5 years, ANTX's P/E ratio has ranged from N/A to N/A, with a median of N/A and an average of N/A. The current P/E of -4.1x places the stock at the N/A percentile of this range. Full historical data spans 2026–2026.
How does ANTX's P/E compare to the S&P 500?
ANTX trades at -4.1x P/E versus the S&P 500 median of 25.1x. The 116% discount to the market suggests lower growth expectations or perceived higher risk.
How does ANTX's valuation compare to Healthcare peers?
AN2 Therapeutics, Inc. P/E of -4.1x compares to the Healthcare sector median of 22.9x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.
What is ANTX's PEG ratio?
ANTX PEG ratio is N/A, based on a P/E of -4.1x and EPS growth of 32.6%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is ANTX's earnings yield?
ANTX earnings yield is N/A, the inverse of its -4.1x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.