Clene Inc. (CLNN) Revenue History
Annual and quarterly revenue from 2018 to 2025
Compound Annual Growth Rate (CAGR)
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CLNN Revenue Growth
Revenue Breakdown (FY 2025)
CLNN's revenue distribution by segment and geography for fiscal year 2025
By Product/Segment
CLNN Revenue Analysis (2018–2025)
As of May 8, 2026, Clene Inc. (CLNN) generated trailing twelve-month (TTM) revenue of $200,000, reflecting significant decline in growth of -15.4% year-over-year. The most recent quarter (Q4 2025) recorded $77,000 in revenue, up 413.3% sequentially.
Looking at the longer-term picture, CLNN's 5-year compound annual growth rate (CAGR) stands at -0.6%, indicating revenue contraction over this period. The company achieved its highest annual revenue of $723,000 in 2021.
Revenue diversification analysis shows CLNN's business is primarily driven by Product (60%), and Royalty (41%). With over half of revenue concentrated in Product, the company maintains significant focus in this area while developing other growth vectors.
When compared to Healthcare sector peers including ACAD (+9.9% YoY), ACIU (-86.9% YoY), and NRXP, CLNN has underperformed the peer group in terms of revenue growth. Compare CLNN vs ACAD →
CLNN Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| CLNNCurrent | $200,000 | -15.4% | -0.6% | -11541.5% | |
 ACAD | $1.1B | +9.9% | +19.4% | 9.8% | |
 ACIU | $4M | -86.9% | -25.4% | -1927.3% | |
 NRXP | $1M | - | - | -1324.4% |
CLNN Historical Revenue Data (2018–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $200K | -41.5% | $157K | 78.5% | $-23,083,000 | -11541.5% |
| 2024 | $342K | -47.7% | $272K | 79.5% | $-33,093,000 | -9676.3% |
| 2023 | $654K | +38.3% | $533K | 81.5% | $-40,540,000 | -6198.8% |
| 2022 | $473K | -34.6% | $447K | 94.5% | $-48,409,000 | -10234.5% |
| 2021 | $723K | +251.0% | $434K | 60.0% | $-49,978,000 | -6912.6% |
| 2020 | $206K | - | $141K | 68.4% | $-20,214,000 | -9812.6% |
| 2019 | $0 | - | $-900,000 | - | $-16,332,000 | - |
| 2018 | $0 | - | $0 | - | $-323,940 | - |
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Start ComparisonCLNN — Frequently Asked Questions
Quick answers to the most common questions about buying CLNN stock.
Is CLNN's revenue growth accelerating or slowing?
CLNN revenue declined -15.4% year-over-year, contrasting with the 5-year CAGR of -0.6%. TTM revenue fell to $200000.00. This reverses the prior growth trend.
What is CLNN's long-term revenue growth rate?
Clene Inc.'s 5-year revenue CAGR of -0.6% reflects the variable expansion pattern. Current YoY growth of -15.4% is below this long-term average.
How is CLNN's revenue distributed by segment?
CLNN reports revenue by product line and geographic region. Annual and quarterly breakdowns from 2018-2025 are available for download. Segment mix reveals concentration and diversification trends.