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6Apr 1, 2026·SEC
Feb 17, 2026·SEC
Jan 6, 2026·SEC
Cyclerion Therapeutics, Inc. (CYCN) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Cyclerion Therapeutics, Inc. (CYCN) stock price & volume — 10-year historical chart
Cyclerion Therapeutics, Inc. (CYCN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Cyclerion Therapeutics, Inc. (CYCN) competitors in Neuroscience and Psychiatry Therapies — business model, growth, and fundamentals comparison
Cyclerion Therapeutics, Inc. (CYCN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Cyclerion Therapeutics, Inc. (CYCN) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 4.51M | 2.3M | 3.32M | 297K | 0 | 2M | 2.07M |
| Revenue Growth % | - | - | - | -49.06% | 44.6% | -91.05% | -100% | - | 3.7% |
| Cost of Goods Sold | 1.75M | 1.53M | 95.14M | 56.41M | 0 | 5.58M | 0 | 0 | 0 |
| COGS % of Revenue | - | - | 2110.94% | 2457.06% | - | 1878.45% | - | - | - |
| Gross Profit | -1.75M▲ 0% | -1.53M▲ 12.4% | -90.63M▼ 5831.5% | -54.12M▲ 40.3% | 3.32M▲ 106.1% | -5.28M▼ 259.1% | 0▲ 100.0% | 2M▲ 0% | 2.07M▲ 3.7% |
| Gross Margin % | - | - | -2010.94% | -2357.06% | 100% | -1778.45% | - | 100% | 100% |
| Gross Profit Growth % | - | 12.44% | -5831.48% | 40.29% | 106.13% | -259.1% | 100% | - | 3.7% |
| Operating Expenses | 93.92M | 115.25M | 34.4M | 27.15M | 58.52M | 13.26M | 12.95M | 5.63M | 7.05M |
| OpEx % of Revenue | - | - | 763.35% | 1182.36% | 1762.5% | 4463.97% | - | 281.4% | 339.78% |
| Selling, General & Admin | 15.12M | 27.54M | 34.4M | 28.82M | 20.62M | 13.26M | 8.33M | 5.34M | 6.09M |
| SG&A % of Revenue | - | - | 763.35% | 1255.05% | 621.08% | 4463.97% | - | 267.1% | 293.54% |
| Research & Development | 78.8M | 87.72M | 95.14M | 56.41M | 37.64M | 5.98M | 1.51M | 286K | 959K |
| R&D % of Revenue | - | - | 2110.94% | 2457.06% | 1133.61% | 2013.13% | - | 14.3% | 46.24% |
| Other Operating Expenses | 0 | 0 | -95.14M | -58.08M | 259K | -5.98M | 3.1M | 0 | 0 |
| Operating Income | -93.92M▲ 0% | -115.25M▼ 22.7% | -125.04M▼ 8.5% | -81.27M▲ 35.0% | -55.2M▲ 32.1% | -18.54M▲ 66.4% | -12.95M▲ 30.1% | -3.63M▲ 72.0% | -4.97M▼ 37.1% |
| Operating Margin % | - | - | -2774.28% | -3539.42% | -1662.5% | -6242.42% | - | -181.4% | -239.78% |
| Operating Income Growth % | - | -22.71% | -8.49% | 35.01% | 32.08% | 66.41% | 30.15% | 71.99% | -37.07% |
| EBITDA | -92.18M | -113.72M | -122.34M | -78.97M | -54.72M | -18.48M | -12.89M | -3.63M | -4.97M |
| EBITDA Margin % | - | - | -2714.38% | -3439.37% | -1648.28% | -6220.54% | - | -181.4% | -239.78% |
| EBITDA Growth % | - | -23.38% | -7.57% | 35.45% | 30.7% | 66.24% | 30.25% | 71.85% | -37.07% |
| D&A (Non-Cash Add-back) | 1.75M | 1.53M | 2.7M | 2.3M | 472K | 65K | 65K | 0 | 0 |
| EBIT | -93.92M | -115.25M | -125.04M | -82.93M | -54.31M | -18.54M | -9.65M | -3.63M | -4.97M |
| Net Interest Income | 0 | 0 | 2.03M | 588K | -16K | 294K | 358K | 208K | 128K |
| Interest Income | 0 | 0 | 2.03M | 588K | 0 | 294K | 358K | 208K | 128K |
| Interest Expense | 0 | 0 | 0 | 0 | 16K | 0 | 0 | 0 | 0 |
| Other Income/Expense | 0 | 0 | 2.03M | 3.46M | 3.55M | 294K | 358K | 571K | 1.45M |
| Pretax Income | -93.92M▲ 0% | -115.25M▼ 22.7% | -123.01M▼ 6.7% | -77.8M▲ 36.8% | -51.65M▲ 33.6% | -18.25M▲ 64.7% | -12.59M▲ 31.0% | -3.06M▲ 75.7% | -3.53M▼ 15.4% |
| Pretax Margin % | - | - | -2729.27% | -3388.59% | -1555.63% | -6143.43% | - | -152.85% | -170.11% |
| Income Tax | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
| Net Income | -93.92M▲ 0% | -115.25M▼ 22.7% | -123.01M▼ 6.7% | -77.8M▲ 36.8% | -51.65M▲ 33.6% | -44.08M▲ 14.7% | -5.26M▲ 88.1% | -3.06M▲ 41.9% | -3.53M▼ 15.4% |
| Net Margin % | - | - | -2729.27% | -3388.59% | -1555.63% | -14841.08% | - | -152.85% | -170.11% |
| Net Income Growth % | - | -22.71% | -6.73% | 36.75% | 33.62% | 14.66% | 88.06% | 41.92% | -15.41% |
| Net Income (Continuing) | -93.92M | -115.25M | -123.01M | -77.8M | -51.65M | -18.25M | -12.59M | -3.06M | -3.53M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | -25.83M | 7.33M | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -68.80▲ 0% | -84.42▼ 22.7% | -88.37▼ 4.7% | -47.80▲ 45.9% | -26.40▲ 44.8% | -20.15▲ 23.7% | -8.99▲ 55.4% | -1.21▲ 86.5% | -1.09▲ 9.9% |
| EPS Growth % | - | -22.7% | -4.68% | 45.91% | 44.77% | 23.67% | 55.38% | 86.54% | 9.92% |
| EPS (Basic) | -68.80 | -84.42 | -88.37 | -47.80 | -26.40 | -20.15 | -8.99 | -1.21 | -1.09 |
| Diluted Shares Outstanding | 1.37M | 1.37M | 1.37M | 1.52M | 1.96M | 2.17M | 2.34M | 2.52M | 3.23M |
| Basic Shares Outstanding | 1.37M | 1.37M | 1.37M | 1.52M | 1.96M | 2.17M | 2.34M | 2.52M | 3.23M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
Cyclerion Therapeutics, Inc. (CYCN) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 1.26M | 879K | 101.2M | 58.5M | 55.46M | 14.82M | 8.02M | 4.22M | 4.63M |
| Cash & Short-Term Investments | 0 | 0 | 97.59M | 54.4M | 53.96M | 13.38M | 7.57M | 3.23M | 3.24M |
| Cash Only | 0 | 0 | 97.59M | 54.4M | 53.96M | 13.38M | 7.57M | 3.23M | 3.24M |
| Short-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accounts Receivable | 0 | 0 | 1.47M | 127K | 100K | 96K | 0 | 556K | 1M |
| Days Sales Outstanding | - | - | 119.37 | 20.19 | 10.99 | 117.98 | - | 101.47 | 175.99 |
| Inventory | 0 | 0 | 0 | 0 | 928K | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | - |
| Other Current Assets | 8K | 12K | 162K | 1.56M | 468K | 537K | 11K | 16K | 11K |
| Total Non-Current Assets | 4.21M | 6.52M | 85.28M | 56.88M | 3.87M | 3.26M | 5.35M | 5.35M | 5.35M |
| Property, Plant & Equipment | 4.13M | 6.5M | 79.75M | 50.27M | 1.47M | 1.22M | 0 | 0 | 0 |
| Fixed Asset Turnover | - | - | 0.06x | 0.05x | 2.26x | 0.24x | - | - | - |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 0 | 4.99M | 0 | 0 | 0 | 5.35M | 5.35M | 5.35M |
| Other Non-Current Assets | 80K | 25K | 540K | 6.61M | 2.41M | 2.04M | 0 | 0 | 0 |
| Total Assets | 5.47M▲ 0% | 7.4M▲ 35.3% | 186.48M▲ 2419.6% | 115.38M▼ 38.1% | 59.33M▼ 48.6% | 18.08M▼ 69.5% | 13.37M▼ 26.0% | 9.57M▼ 28.4% | 9.98M▲ 4.3% |
| Asset Turnover | - | - | 0.02x | 0.02x | 0.06x | 0.02x | - | 0.21x | 0.21x |
| Asset Growth % | - | 35.3% | 2419.63% | -38.13% | -48.58% | -69.53% | -26.02% | -28.41% | 4.28% |
| Total Current Liabilities | 14.04M | 17.85M | 18.25M | 16.95M | 11.09M | 7.63M | 2.09M | 725K | 900K |
| Accounts Payable | 1.8M | 2.78M | 3.31M | 1.15M | 1.83M | 2.97M | 1.2M | 390K | 508K |
| Days Payables Outstanding | 376.92 | 664.31 | 12.7 | 7.43 | - | 194.31 | - | - | - |
| Short-Term Debt | 0 | 0 | 3.42M | 3.51M | 0 | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 5.62M | 7.27M | 5.05M | 176K | 7.28M | 68K | 102K | 63K | 51K |
| Current Ratio | 0.09x | 0.05x | 5.55x | 3.45x | 5.00x | 1.94x | 3.85x | 5.83x | 5.15x |
| Quick Ratio | 0.09x | 0.05x | 5.55x | 3.45x | 4.92x | 1.94x | 3.85x | 5.83x | 5.15x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 0 | 0 | 70.5M | 38.93M | 0 | 0 | 0 | 0 | 0 |
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 0 | 0 | 70.5M | 38.93M | 0 | 0 | 0 | 0 | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Total Liabilities | 14.04M | 17.85M | 88.75M | 55.88M | 11.09M | 7.63M | 2.09M | 725K | 900K |
| Total Debt | 0 | 0 | 73.92M | 45.73M | 0 | 0 | 0 | 0 | 0 |
| Net Debt | 0 | 0 | -23.68M | -8.66M | -53.96M | -13.38M | -7.57M | -3.23M | -3.24M |
| Debt / Equity | - | - | 0.76x | 0.77x | - | - | - | - | - |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Interest Coverage | - | - | - | - | -3394.63x | - | - | - | - |
| Total Equity | -8.57M▲ 0% | -10.45M▼ 21.9% | 97.73M▲ 1035.7% | 59.49M▼ 39.1% | 48.25M▼ 18.9% | 10.45M▼ 78.3% | 11.29M▲ 8.0% | 8.85M▼ 21.6% | 9.09M▲ 2.7% |
| Equity Growth % | - | -21.92% | 1035.65% | -39.12% | -18.9% | -78.34% | 8% | -21.6% | 2.66% |
| Book Value per Share | -6.28 | -7.65 | 71.39 | 39.14 | 24.65 | 4.81 | 4.83 | 3.51 | 2.82 |
| Total Shareholders' Equity | -8.57M | -10.45M | 97.73M | 59.49M | 48.25M | 10.45M | 11.29M | 8.85M | 9.09M |
| Common Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Retained Earnings | 0 | 0 | -85.63M | -163.43M | -215.08M | -259.15M | -264.42M | -267.49M | -271.02M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -15.87M | -15.49M | -20K | -27K | -23K | -20K | -12K | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cyclerion Therapeutics, Inc. (CYCN) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -81.22M | -97.5M | -102.22M | -72.49M | -36.52M | -40.61M | -21.25M | -4.33M | -3.31M |
| Operating CF Margin % | - | - | -2267.92% | -3157.23% | -1099.91% | -13673.74% | - | -216.65% | -159.79% |
| Operating CF Growth % | - | -20.05% | -4.83% | 29.08% | 49.62% | -11.21% | 47.69% | 79.6% | 23.52% |
| Net Income | -93.92M | -115.25M | -123.01M | -77.8M | -51.65M | -18.25M | -12.59M | -3.06M | -3.53M |
| Depreciation & Amortization | 1.75M | 1.53M | 2.7M | 2.3M | 472K | 65K | 0 | 0 | 0 |
| Stock-Based Compensation | 9.49M | 12.43M | 19.63M | 14.99M | 9.61M | 0 | 0 | 625K | 441K |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 12.59M | 14.51M | 751K | -4.38M | 3.64M | -19.58M | -4.05M | -363K | 0 |
| Working Capital Changes | 1.47M | 3.79M | -2.29M | -7.59M | 1.41M | -2.85M | -4.6M | -1.54M | -227K |
| Change in Receivables | 0 | 0 | -1.47M | 1.35M | 27K | 4K | 96K | -556K | -444K |
| Change in Inventory | 0 | 0 | -3.18M | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 392K | 979K | -250K | -1.1M | 393K | 1.14M | -1.77M | -445K | 118K |
| Cash from Investing | -1.4M | -3.44M | -6.71M | 18K | 1.46M | 0 | 10.4M | 0 | 0 |
| Capital Expenditures | -1.4M | -3.44M | -6.89M | -1.52M | -7K | 0 | 0 | 0 | 0 |
| CapEx % of Revenue | - | - | 152.83% | 66.38% | 0.21% | - | - | - | - |
| Acquisitions | 0 | 0 | 173K | 0 | 0 | 0 | 10.4M | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 173K | 1.54M | 1.46M | 0 | 0 | 0 | 0 |
| Cash from Financing | 82.62M | 100.94M | 211.57M | 28.09M | 30.79M | 29K | 5.02M | 0 | 3.32M |
| Debt Issued (Net) | 0 | 0 | 0 | 3.51M | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 0 | 0 | 175M | 24.25M | 30.5M | 29K | 5.02M | 0 | 1.25M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -130K |
| Other Financing | 82.62M | 100.94M | 36.57M | 331K | 282K | 0 | 0 | 0 | 2.08M |
| Net Change in Cash | 0▲ 0% | 0▲ 0% | 102.62M▲ 0% | -44.39M▼ 143.3% | -4.27M▲ 90.4% | -40.58M▼ 850.1% | -5.81M▲ 85.7% | -4.34M▲ 25.3% | 8K▲ 100.2% |
| Free Cash Flow | -82.62M▲ 0% | -100.94M▼ 22.2% | -109.1M▼ 8.1% | -74.01M▲ 32.2% | -36.52M▲ 50.7% | -40.61M▼ 11.2% | -21.25M▲ 47.7% | -4.33M▲ 79.6% | -3.31M▲ 23.5% |
| FCF Margin % | - | - | -2420.75% | -3223.61% | -1100.12% | -13673.74% | - | -216.65% | -159.79% |
| FCF Growth % | - | -22.17% | -8.09% | 32.16% | 50.65% | -11.19% | 47.69% | 79.6% | 23.52% |
| FCF per Share | -60.52 | -73.94 | -79.70 | -48.69 | -18.66 | -18.69 | -9.09 | -1.72 | -1.03 |
| FCF Conversion (FCF/Net Income) | 0.86x | 0.85x | 0.83x | 0.93x | 0.71x | 0.92x | 4.04x | 1.42x | 0.94x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cyclerion Therapeutics, Inc. (CYCN) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | - | - | -281.86% | -98.97% | -95.87% | -150.19% | -48.42% | -30.36% | -39.34% |
| Return on Invested Capital (ROIC) | - | - | -294.86% | -97.61% | -183.5% | - | -2468.42% | -58.3% | -65.07% |
| Gross Margin | - | - | -2010.94% | -2357.06% | 100% | -1778.45% | - | 100% | 100% |
| Net Margin | - | - | -2729.27% | -3388.59% | -1555.63% | -14841.08% | - | -152.85% | -170.11% |
| Debt / Equity | - | - | 0.76x | 0.77x | - | - | - | - | - |
| Interest Coverage | - | - | - | - | -3394.63x | - | - | - | - |
| FCF Conversion | 0.86x | 0.85x | 0.83x | 0.93x | 0.71x | 0.92x | 4.04x | 1.42x | 0.94x |
| Revenue Growth | - | - | - | -49.06% | 44.6% | -91.05% | -100% | - | 3.7% |
Cyclerion Therapeutics, Inc. (CYCN) SEC filings — annual & quarterly reports (10-K, 10-Q)
Apr 1, 2026·SEC
Feb 17, 2026·SEC
Jan 6, 2026·SEC
Cyclerion Therapeutics, Inc. (CYCN) stock FAQ — growth, dividends, profitability & financials explained
Cyclerion Therapeutics, Inc. (CYCN) reported $2.1M in revenue for fiscal year 2025.
Cyclerion Therapeutics, Inc. (CYCN) grew revenue by 3.7% over the past year. Growth has been modest.
Cyclerion Therapeutics, Inc. (CYCN) reported a net loss of $3.5M for fiscal year 2025.
Cyclerion Therapeutics, Inc. (CYCN) has a return on equity (ROE) of -39.3%. Negative ROE indicates the company is unprofitable.
Cyclerion Therapeutics, Inc. (CYCN) had negative free cash flow of $3.3M in fiscal year 2025, likely due to heavy capital investments.
Cyclerion Therapeutics, Inc. (CYCN) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates