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DFTXDefinium Therapeutics, Inc.
$33.00$4.5B
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DFTX logo

Definium Therapeutics, Inc.

DFTX
NASDAQ
$33.00
At close - Nov 12, 4:00 PM EST - USD
Market Cap$4.43B
P/E-13.4x
52W High$49.70
Volume1.2M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Accelerating Clinical Burn Challenges Capital Runway Sustainability

MindMed is currently in a high-stakes, pre-revenue development phase, with its valuation heavily contingent on the successful progression of the MM-120 candidate through Phase 3 clinical trials.

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsMixed
Explore valuation models
MARKET ACTION

DFTX price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

3/12 Beats

EPS beat 3 of last 12 quarters

02

Valuation risk

-188% Peers

P/E is 188% below peer median

03

Market leadership

N/A

RS data unavailable

04

Mixed Trend

Mixed

Price < 50DMA but > 200DMA

Next CatalystEstimated earnings · Feb 9

Market performance

Price History →

Trailing total returns as of 11/13/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
DFTX+141.94%
S&P 500 (^GSPC)+10.82%
1-Year Return
DFTX+171.83%
S&P 500 (^GSPC)+10.79%
3-Year Return
DFTX+1258.02%
S&P 500 (^GSPC)+57.40%
5-Year Return
DFTX-7.95%
S&P 500 (^GSPC)+47.39%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$184M-69.1% YoY
Free cash flow FY25
-$132M-66.3% YoY
Operating margin FY25
-
ROIC (FY25)-389.5%
Avg ROIC 5Y-2946.4%
ROE (TTM)-54%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate3/12 (25%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 9, 2026
-$0.46+18.3%
vs -$0.56
—
vs —
Q3 2026
Aug 6, 2026
-$1.44-166.2%
vs -$0.54
—
vs —
Q2 2026
May 7, 2026
-$0.71-51.1%
vs -$0.47
—
vs —
Q1 2026
Feb 26, 2026
-$0.51-5.4%
vs -$0.48
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
MarketBeat·2d ago
Definium Therapeutics Eyes FDA Filing for LSD Treatment After Three Positive Phase 3 Studies

Definium Therapeutics NASDAQ: DFTX plans to submit a new drug application to the U.S. Food and Drug Administration for its LSD formulation DT120 in the first half of next year, following positive results from three Phase 3 studies, Chief Medical Officer Daniel Karlin said.

Seeking Alpha·3d ago
Definium Q3 Earnings: Psychedelics Approval Beckons But Valuation Seems Inflated

Definium Therapeutics, Inc. reported strong Phase 3 results for DT120 in both GAD and MDD, positioning for an NDA filing in H1 2026. DFTX holds over $1bn in cash, supporting operations into 2030, and is preparing for a potential commercial launch in 2027. Despite class-leading efficacy data and regulatory momentum, I maintain a Hold rating due to high valuation, patent challenges, and uncertain market dynamics.

Seeking Alpha·3d ago
Definium Therapeutics, Inc. (DFTX) Q3 2026 Earnings Call Transcript

Definium Therapeutics, Inc. (DFTX) Q3 2026 Earnings Call Transcript

MarketBeat·4d ago
What Definium Therapeutics (DFTX) Said on Its Q3 Earnings Call

Definium Therapeutics NASDAQ: DFTX plans to file a new drug application for its psychiatric treatment candidate DT120 ODT in the first half of 2027, following positive results from three Phase 3 studies in generalized anxiety disorder and major depressive disorder, executives said on the company's third-quarter earnings call.

Filtered for Definium Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark DFTX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Definium Therapeutics, Inc. (DFTX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
DFTX logoDFTXDefinium Therapeutics, Inc.Current
$33.00$4.43B-13.43——-54.04%—
CMPS logoCMPSCOMPASS Pathways plc
$9.12$1.23B-5.57——-212.85%—
HELP logoHELPHelus Pharma Inc.
$8.86$549.18M-2.53-9561.61%—-70.99%—
MGRX logoMGRXMangoceuticals, Inc.
$0.19$3.14M-0.21-25.96%-4791.48%-106.13%—
SILO logoSILOSilo Pharma, Inc.
$1.91$2.16M-0.47—-8269.53%-81.74%—
LWAY logoLWAYLifeway Foods, Inc.
$20.89$319.24M29.3813.74%4.48%12.66%—

Compare DFTX vs Peers

Definium Therapeutics, Inc. (DFTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CMPS

Most directly comparable listed peer for DFTX.

Scale Benchmark

vs JAZZ

Larger-name benchmark to compare DFTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs CMPS, HELP, MGRX, SILO

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

DFTX SEC Filings & Documents

Definium Therapeutics, Inc. (DFTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Sep 14, 2026·SEC

Material company update

Sep 8, 2026·SEC

Material company update

Aug 12, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 6, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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DFTX Frequently Asked Questions

Definium Therapeutics, Inc. (DFTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is DFTX profitable?

No. Definium Therapeutics, Inc. (DFTX) reported a net loss of $337.5M over the trailing twelve months.

Dividend & Returns
What is DFTX's return on equity?

Definium Therapeutics, Inc. (DFTX) had a return on equity (ROE) of -54.0% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Definium Therapeutics, Inc.'s free cash flow?

Definium Therapeutics, Inc. (DFTX) had negative free cash flow of $190.3M over the trailing twelve months.

What if you invested $1,000 in DFTX back in 2015?

Total return calculator · dividends reinvested · 11+ years of data

See returns →