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MGTXMeiraGTx Holdings plc
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MGTX logoMeiraGTx Holdings plc(MGTX)Earnings, Financials & Key Ratios

MGTX•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutMeiraGTx Holdings plc, a clinical stage gene therapy company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited blindness, as well as Xerostomia following radiation treatment for head and neck cancers; degenerative diseases; neurodegenerative diseases, such as amyotrophic lateral sclerosis; and Parkinson's diseases. Its programs in clinical development include Phase 1/2 clinical stage programs in Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, and radiation-induced Xerostomia, as well as Parkinson's program. The company also focuses on initiating a clinical program in xerostomia related to Sjogren's syndrome and have preclinical programs in neurodegenerative diseases. It has a research collaboration agreement with Janssen Pharmaceuticals, Inc. to develop regulatable gene therapy treatment using the company's proprietary riboswitch technology. MeiraGTx Holdings plc was incorporated in 2015 and is based in New York, New York.Show more
  • Revenue$81M+144.6%
  • EBITDA-$106M+30.0%
  • Net Income-$114M+22.7%
  • EPS (Diluted)-1.42+33.0%
  • Gross Margin94.05%+229.9%
  • EBITDA Margin-130.2%+71.4%
  • Operating Margin-130.2%+73.6%
  • Net Margin-140.31%+68.4%
  • ROE-368.19%-156.6%

MGTX Key Insights

MeiraGTx Holdings plc (MGTX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 85 (top 15%)
  • ✓Strong 5Y sales CAGR of 39.2%
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Profits declining 14.5% over 5 years
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Shares diluted 15.2% in last year

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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MGTX Price & Volume

MeiraGTx Holdings plc (MGTX) stock price & volume — 10-year historical chart

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MGTX Growth Metrics

MeiraGTx Holdings plc (MGTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years39.22%
3 Years72.27%
TTM131.13%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM27.97%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM36.21%

Return on Capital

10 Years-92.29%
5 Years-52.6%
3 Years-63.14%
Last Year-64.06%

MGTX Recent Earnings

MeiraGTx Holdings plc (MGTX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/12 qtrs (25%)●Beat Revenue 4/12 qtrs (33%)
Q2 2026Latest
May 14, 2026
Metric
Actual
Est
EPS
$0.57-32.6%
$0.43
Rev
$293,000-98.3%
$17M
Q2 2026
Mar 26, 2026
Metric
Actual
Est
EPS
$0.19+131.7%
$0.60
Rev
$75M+5115.3%
$1M
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.62-24.0%
$0.50
Rev
$410,000-89.4%
$4M
Q3 2025
Aug 14, 2025
Metric
Actual
Est
EPS
$0.48+7.7%
$0.52
Rev
$4M-43.1%
$6M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$0.57vs $0.43-32.6%
$293,000vs $17M-98.3%
Q2 2026Mar 26, 2026
$0.19vs $0.60+131.7%
$75Mvs $1M+5115.3%
Q4 2025Nov 13, 2025
$0.62vs $0.50-24.0%
$410,000vs $4M-89.4%
Q3 2025Aug 14, 2025
$0.48vs $0.52+7.7%
$4Mvs $6M-43.1%
Based on last 12 quarters of dataView full earnings history →

MGTX Peer Comparison

MeiraGTx Holdings plc (MGTX) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ADVM logoADVMAdverum Biotechnologies, Inc.Direct Competitor96.26M4.36-0.66-72.22%-189.84%1.30
OCGN logoOCGNOcugen, Inc.Direct Competitor419.77M1.24-5.398.83%-16.05%-1279.88%
EDIT logoEDITEditas Medicine, Inc.Direct Competitor263.37M2.69-1.4925.39%-281.59%-6.77%2.81
CRSP logoCRSPCRISPR Therapeutics AGProduct Competitor5.22B54.09-8.36-89.97%-138.57%-30.88%0.21
NTLA logoNTLAIntellia Therapeutics, Inc.Product Competitor1.76B15.67-4.1116.92%-5.97%-57.27%0.14
BEAM logoBEAMBeam Therapeutics Inc.Product Competitor3.51B34.14-42.15120.01%-49.17%-5.89%0.24
SGMO logoSGMOSangamo Therapeutics, Inc.Product Competitor74.57M0.18-0.41-31.57%-356.89%-28.92%
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Product Competitor11.52B81.82-6706.56232.58%-48.38%-55.09%0.73

Compare MGTX vs Peers

MeiraGTx Holdings plc (MGTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ADVM

Most directly comparable listed peer for MGTX.

Scale Benchmark

vs REGN

Larger-name benchmark to compare MGTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs ADVM, OCGN, EDIT, CRSP

MGTX Income Statement

MeiraGTx Holdings plc (MGTX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0013.29M15.56M37.7M15.92M14.02M33.28M81.39M79.76M
Revenue Growth %
---17.09%142.25%-57.77%-11.95%137.42%144.57%131.13%
Cost of Goods Sold
679.18K2.05M0000023.79M4.84M6.67M
COGS % of Revenue
-------71.49%5.95%-
Gross Profit
-679.18K▲ 0%
-2.05M▼ 202.3%
13.29M▲ 747.5%
15.56M▲ 17.1%
37.7M▲ 142.2%
15.92M▼ 57.8%
14.02M▼ 12.0%
9.49M▼ 32.3%
76.55M▲ 706.8%
73.09M▲ 0%
Gross Margin %
--100%100%100%100%100%28.51%94.05%91.64%
Gross Profit Growth %
-179.4%-202.27%747.46%17.09%142.25%-57.77%-11.95%-32.31%706.79%-
Operating Expenses
31.68M78.1M71.56M78.12M110.46M132.28M151.08M173.7M182.52M178.28M
OpEx % of Revenue
--538.37%501.94%292.99%830.87%1077.82%521.95%224.25%-
Selling, General & Admin
9.33M44.48M46.68M44.21M43.77M46.55M47.29M54.22M52.9M52.46M
SG&A % of Revenue
--351.22%284.05%116.08%292.4%337.4%162.91%64.99%-
Research & Development
22.36M33.62M24.88M33.91M66.69M85.72M103.78M119.48M129.62M128.82M
R&D % of Revenue
--187.15%217.89%176.9%538.47%740.42%359.04%159.25%-
Other Operating Expenses
-553.5K83.08K0000000-1000K
Operating Income
-31.68M▲ 0%
-78.1M▼ 146.5%
-58.27M▲ 25.4%
-62.55M▼ 7.4%
-72.76M▼ 16.3%
-116.36M▼ 59.9%
-137.06M▼ 17.8%
-164.21M▼ 19.8%
-105.97M▲ 35.5%
-105.19M▲ 0%
Operating Margin %
---438.37%-401.94%-192.99%-730.87%-977.82%-493.44%-130.2%-131.89%
Operating Income Growth %
-57.91%-146.5%25.4%-7.36%-16.31%-59.92%-17.8%-19.81%35.47%-
EBITDA
-31.01M-76.05M-56.03M-58.38M-64.89M-107.75M-123.33M-151.38M-105.97M-92.37M
EBITDA Margin %
---421.53%-375.13%-172.1%-676.83%-879.87%-454.89%-130.2%-115.82%
EBITDA Growth %
-56.42%-145.28%26.33%-4.2%-11.14%-66.07%-14.46%-22.75%30%36.97%
D&A (Non-Cash Add-back)
679.18K2.05M2.24M4.17M7.87M8.6M13.73M12.83M012.81M
EBIT
-31.68M-78.1M-54.7M-57.85M-79.27M-124.67M-70.78M-134.52M-105.97M-105.88M
Net Interest Income
-16.79K19.98K321.99K1.14M-76K-4.17M-10.97M-9.13M-10.38M-10.97M
Interest Income
26.07K53.41K370.6K1.28M212K777K2.27M4.14M1.82M1.04M
Interest Expense
42.86K33.43K48.61K139.2K288K4.95M13.24M13.27M12.2M12M
Other Income/Expense
640.19K-5.24M3.52M4.56M-6.8M-13.26M53.03M16.42M-8.23M-15.34M
Pretax Income
-31.04M▲ 0%
-83.34M▼ 168.5%
-54.75M▲ 34.3%
-57.99M▼ 5.9%
-79.56M▼ 37.2%
-129.62M▼ 62.9%
-84.03M▲ 35.2%
-147.79M▼ 75.9%
-114.2M▲ 22.7%
-120.53M▲ 0%
Pretax Margin %
---411.87%-372.63%-211.03%-814.16%-599.46%-444.1%-140.31%-151.12%
Income Tax
0-474.39K00000000
Effective Tax Rate %
0%0.57%0%0%0%0%0%0%0%0%
Net Income
-31.04M▲ 0%
-82.87M▼ 166.9%
-54.75M▲ 33.9%
-57.99M▼ 5.9%
-79.56M▼ 37.2%
-129.62M▼ 62.9%
-84.03M▲ 35.2%
-147.79M▼ 75.9%
-114.2M▲ 22.7%
-120.53M▲ 0%
Net Margin %
---411.87%-372.63%-211.03%-814.16%-599.46%-444.1%-140.31%-151.12%
Net Income Growth %
-59.31%-166.93%33.93%-5.93%-37.19%-62.91%35.17%-75.89%22.73%27.97%
Net Income (Continuing)
-31.04M-82.87M-54.75M-57.99M-79.56M-129.62M-84.03M-147.79M-114.2M-120.53M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-3.62▲ 0%
-4.37▼ 20.7%
-1.58▲ 63.8%
-1.43▲ 9.5%
-1.80▼ 25.9%
-2.87▼ 59.4%
-1.49▲ 48.1%
-2.12▼ 42.3%
-1.42▲ 33.0%
-1.48▲ 0%
EPS Growth %
-258.42%-20.72%63.84%9.49%-25.87%-59.44%48.08%-42.28%33.02%36.21%
EPS (Basic)
-3.62-4.37-1.58-1.43-1.80-2.87-1.49-2.12-1.42-
Diluted Shares Outstanding
8.57M18.95M33.16M37.72M44.14M45.18M56.49M69.82M80.43M81.3M
Basic Shares Outstanding
8.57M18.95M33.16M37.72M44.14M45.18M56.49M69.82M80.43M81.3M
Dividend Payout Ratio
----------

MGTX Balance Sheet

MeiraGTx Holdings plc (MGTX) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
11.48M74.65M268.98M272.58M183.24M154.34M159.62M123.52M91.76M96.2M
Cash & Short-Term Investments
8.55M68.08M227.23M209.52M137.7M115.52M129.57M103.66M65.93M71.54M
Cash Only
8.55M68.08M227.23M209.52M137.7M115.52M129.57M103.66M65.93M71.54M
Short-Term Investments
0000000000
Accounts Receivable
0037.11M55.41M35.02M29.02M23.41M10.63M3M3.26M
Days Sales Outstanding
--1.02K1.3K339.02665.41609.72116.5713.4528.45
Inventory
0000000385K00
Days Inventory Outstanding
-------5.91-4.3
Other Current Assets
965.23K4.63M170.59K564.44K2.42M1.67M1.02M2.02M22.83M21.4M
Total Non-Current Assets
14.38M22.24M54.91M91.12M136.92M163.9M167.12M146.23M152.67M148.45M
Property, Plant & Equipment
14.26M22.01M52.86M87.12M126.29M154.09M156.24M135.65M141.93M137.53M
Fixed Asset Turnover
--0.25x0.18x0.30x0.10x0.09x0.25x0.57x0.56x
Goodwill
0000000000
Intangible Assets
00777.65K2.97M2.57M2.08M1.12M821K578K494K
Long-Term Investments
123.38K123.38K123.38K06.66M6.33M6.77M6.75M6.75M29.26M
Other Non-Current Assets
0105.08K1.15M1.03M1.4M1.4M3M3.01M3.41M3.68M
Total Assets
25.85M▲ 0%
96.89M▲ 274.8%
323.89M▲ 234.3%
363.7M▲ 12.3%
320.16M▼ 12.0%
318.24M▼ 0.6%
326.74M▲ 2.7%
269.75M▼ 17.4%
244.43M▼ 9.4%
244.66M▲ 0%
Asset Turnover
--0.04x0.04x0.12x0.05x0.04x0.12x0.33x0.36x
Asset Growth %
14.65%274.77%234.27%12.29%-11.97%-0.6%2.67%-17.44%-9.39%-62.38%
Total Current Liabilities
21.4M15.5M49.2M54.15M68.13M82.07M67.08M60.78M122.56M176.13M
Accounts Payable
7.06M3.04M3.76M7.13M15.35M16.62M16.04M23.59M10.07M16.66M
Days Payables Outstanding
3.79K541-----361.85758.641.01K
Short-Term Debt
1.44M27.2K1.67M2.58M000027.54M27.13M
Deferred Revenue (Current)
10.19M11.99M25.68M23.54M21.82M15.12M2.93M4.83M1.78M9.42M
Other Current Liabilities
2.68M6.14M11.23M17.09M6.03M16.23M41.28M12.1M83.18M130.35M
Current Ratio
0.54x4.82x5.47x5.03x2.69x1.88x2.38x2.03x0.75x0.55x
Quick Ratio
0.54x4.82x5.47x5.03x2.69x1.88x2.38x2.03x0.75x0.55x
Cash Conversion Cycle
--------239.38--977.38
Total Non-Current Liabilities
51.82M336.48K83.89M70.99M66.64M118.43M121.49M141.14M127.67M126.66M
Long-Term Debt
0000071.03M72.12M73.22M49.69M49.7M
Capital Lease Obligations
34.3K7.1K21.5M19.67M20.36M17.33M12.95M7.52M11.46M37.75M
Deferred Tax Liabilities
-266.29K-201.26K195.05K213.72K196K186K0000
Other Non-Current Liabilities
51.78M329.38K1.65M1.81M3.03M2.44M2.4M2.82M1.4M1.41M
Total Liabilities
73.22M15.84M133.09M125.14M134.76M200.5M188.57M201.92M250.22M302.79M
Total Debt
1.51M34.3K23.18M22.25M23.73M92.25M89.26M84.8M88.69M87.53M
Net Debt
-7.04M-68.05M-204.05M-187.27M-113.97M-23.27M-40.3M-18.86M22.75M15.99M
Debt / Equity
-0.00x0.12x0.09x0.13x0.78x0.65x1.25x--1.51x
Debt / EBITDA
----------0.95x
Net Debt / EBITDA
----------0.17x
Interest Coverage
-739.21x-2336.42x-1125.19x-415.60x-275.25x-25.21x-5.34x-10.14x-8.69x-8.82x
Total Equity
-47.37M▲ 0%
81.06M▲ 271.1%
190.8M▲ 135.4%
238.56M▲ 25.0%
185.4M▼ 22.3%
117.74M▼ 36.5%
138.18M▲ 17.4%
67.83M▼ 50.9%
-5.79M▼ 108.5%
-58.13M▲ 0%
Equity Growth %
-176.36%271.14%135.39%25.03%-22.28%-36.5%17.36%-50.91%-108.54%-622.83%
Book Value per Share
-5.534.285.756.324.202.612.450.97-0.07-0.71
Total Shareholders' Equity
-47.37M81.06M190.8M238.56M185.4M117.74M138.18M67.83M-5.79M-58.13M
Common Stock
3421.06K1.43K1.72K2K2K2K3K3K3K
Retained Earnings
-65.42M-148.29M-203.04M-261.03M-340.59M-470.2M-554.23M-702.02M-816.22M-862.54M
Treasury Stock
000000000-18.19M
Accumulated OCI
-2.02M293.67K-1.79M-4.9M-2.67M6.05M-1.44M-3.72M2.41M2.58M
Minority Interest
0000000000

MGTX Cash Flow Statement

MeiraGTx Holdings plc (MGTX) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-18.06M-58.89M20.04M-63.97M-10.53M-73.1M-105.36M-104.5M-46.36M8.28M
Operating CF Margin %
--150.8%-411.02%-27.93%-459.16%-751.69%-314%-56.96%-
Operating CF Growth %
-25.66%-226.15%134.04%-419.12%83.54%-594.19%-44.14%0.83%55.64%374%
Net Income
-31.04M-82.87M-54.75M-57.99M-79.56M-129.62M-84.03M-147.79M-114.2M-120.53M
Depreciation & Amortization
679.18K2.05M2.24M4.17M7.87M8.6M13.72M12.68M12.7M28.6M
Stock-Based Compensation
2.96M17.88M15.93M18.42M20.78M28.62M27.72M25.19M22.11M44.27M
Deferred Taxes
-1.21M-474.39K00000000
Other Non-Cash Items
2.03M8.43M-105.01K4.08M9.1M9.67M-61.8M-24.22M5.01M179.71M
Working Capital Changes
8.53M-3.92M56.73M-32.64M31.28M9.62M-983K29.64M28.03M84.29M
Change in Receivables
00-32.29M-16.12M16.7M5.17M4.83M9.43M-7.27M-7.36M
Change in Inventory
0000000-387K428K631K
Change in Payables
4.73M-2.12M-8.68K1.57M13.35M3.74M2.33M10.74M-12.31M-1.95M
Cash from Investing
-10.54M-11.26M-9.37M-37.02M-61.72M-44.96M34.03M23.48M-4.11M-4.66M
Capital Expenditures
-10.54M-11.26M-8.98M-34.89M-55.22M-44.96M-20.17M-4.96M-3.83M-10.62M
CapEx % of Revenue
--67.56%224.2%146.46%282.43%143.93%14.89%4.7%13.32%
Acquisitions
00-389.66K0-6.5M0000473K
Investments
----------
Other Investing
000-2.13M0054.21M28.43M-281K5.49M
Cash from Financing
19.34M130.04M148.23M82.73M1.71M95.2M84.02M54.53M12.27M446K
Debt Issued (Net)
2.48M-30.85K-24.86K-23K-1K75M00-29K-43K
Equity Issued (Net)
00155.2M87.05M025M91.95M59.39M15.33M6.43M
Dividends Paid
0000000000
Share Repurchases
000000000-18.42M
Other Financing
16.86M130.07M-6.94M-4.3M1.71M-4.8M-7.93M-4.86M-3.03M-5.95M
Net Change in Cash
-9.25M▲ 0%
59.53M▲ 743.6%
159.15M▲ 167.3%
-17.84M▼ 111.2%
-71.82M▼ 302.6%
-22.19M▲ 69.1%
15.13M▲ 168.2%
-24.98M▼ 265.1%
-37.48M▼ 50.0%
5.19M▲ 0%
Free Cash Flow
-28.59M▲ 0%
-70.15M▼ 145.3%
11.06M▲ 115.8%
-100.99M▼ 1012.7%
-65.75M▲ 34.9%
-118.06M▼ 79.6%
-125.54M▼ 6.3%
-109.45M▲ 12.8%
-50.19M▲ 54.1%
-2.34M▲ 0%
FCF Margin %
--83.24%-648.89%-174.39%-741.59%-895.62%-328.89%-61.66%-2.94%
FCF Growth %
-68.56%-145.34%115.77%-1012.71%34.9%-79.57%-6.33%12.82%54.15%97.86%
FCF per Share
-3.34-3.700.33-2.68-1.49-2.61-2.22-1.57-0.62-0.03
FCF Conversion (FCF/Net Income)
0.58x0.71x-0.37x1.10x0.13x0.56x1.25x0.71x0.41x0.02x
Interest Paid
001.46K3K139K329K13.05M12.03M05.41M
Taxes Paid
0000000000

MGTX Key Ratios

MeiraGTx Holdings plc (MGTX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
--491.87%-40.28%-27.01%-37.53%-85.52%-65.67%-143.48%-368.19%474.91%
Return on Invested Capital (ROIC)
--450.13%--246.7%-88.93%-105.2%-106.89%-167.75%-241.1%-537.14%
Gross Margin
--100%100%100%100%100%28.51%94.05%91.64%
Net Margin
---411.87%-372.63%-211.03%-814.16%-599.46%-444.1%-140.31%-151.12%
Debt / Equity
-0.00x0.12x0.09x0.13x0.78x0.65x1.25x--1.51x
Interest Coverage
-739.21x-2336.42x-1125.19x-415.60x-275.25x-25.21x-5.34x-10.14x-8.69x-8.82x
FCF Conversion
0.58x0.71x-0.37x1.10x0.13x0.56x1.25x0.71x0.41x0.02x
Revenue Growth
---17.09%142.25%-57.77%-11.95%137.42%144.57%131.13%
Related:MGTX Dividend History·MGTX Revenue History·MGTX Price History·MGTX P/E History·MGTX Financial Ratios·MGTX Institutional Holders

MGTX SEC Filings & Documents

MeiraGTx Holdings plc (MGTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 14, 2026·SEC

Material company update

Apr 24, 2026·SEC

Material company update

Apr 16, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 30, 2026·SEC

FY 2025

Mar 13, 2025·SEC

FY 2024

Mar 15, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 14, 2025·SEC

MGTX Frequently Asked Questions

MeiraGTx Holdings plc (MGTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

MeiraGTx Holdings plc (MGTX) reported $79.8M in revenue for fiscal year 2025.

MeiraGTx Holdings plc (MGTX) grew revenue by 144.6% over the past year. This is strong growth.

MeiraGTx Holdings plc (MGTX) reported a net loss of $120.5M for fiscal year 2025.

Dividend & Returns

MeiraGTx Holdings plc (MGTX) has a return on equity (ROE) of -368.2%. Negative ROE indicates the company is unprofitable.

MeiraGTx Holdings plc (MGTX) had negative free cash flow of $2.3M in fiscal year 2025, likely due to heavy capital investments.

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