MeiraGTx Holdings plc (MGTX) Financial Ratios
10 years of historical data (2016–2025) · Healthcare · Biotechnology
EV/EBITDA
N/A
—
5yr avg: N/A
P/FCF
N/A
—
5yr avg: N/A
30Y Low60.0·High60.0
P/B Ratio
↑
N/A
—
5yr avg: 4.32
30Y Low2.3·High6.3
ROE
↓
-368.2%
↑-163% vs avg
5yr avg: -140.1%
30Y Low-492%·High-27%
Debt/EBITDA
N/A
—
5yr avg: N/A
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
MGTX Valuation Multiples
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
MeiraGTx Holdings plc currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $1.1B | $639M | $425M | $397M | $295M | $1.0B | $571M | $664M | $183M | — | — |
| Enterprise Value | $1.1B | $662M | $406M | $356M | $271M | $934M | $384M | $460M | $115M | — | — |
| P/E Ratio → | -8.08 | — | — | — | — | — | — | — | — | — | — |
| P/S Ratio | 13.06 | 7.86 | 12.78 | 28.29 | 18.50 | 27.79 | 36.70 | 49.95 | — | — | — |
| P/B Ratio | — | — | 6.27 | 2.87 | 2.50 | 5.65 | 2.39 | 3.48 | 2.25 | — | — |
| P/FCF | — | — | — | — | — | — | — | 60.00 | — | — | — |
| P/OCF | — | — | — | — | — | — | — | 33.12 | — | — | — |
P/E links to full P/E history page with 30-year chart
MGTX EV Ratios
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 8.14 | 12.21 | 25.41 | 17.04 | 24.77 | 24.67 | 34.60 | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | 41.56 | — | — | — |
MGTX Profitability
Margins and return-on-capital ratios measuring operating efficiency
MeiraGTx Holdings plc earns an operating margin of -130.2%. Operating margins have expanded from -977.8% to -130.2% over the past 3 years, signaling improving operational efficiency. A negative ROE of -368.2% indicates the company is currently destroying shareholder equity.
Margins
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 94.0% | 94.0% | 28.5% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | — | — | — |
| Operating Margin | -130.2% | -130.2% | -493.4% | -977.8% | -730.9% | -193.0% | -401.9% | -438.4% | — | — | — |
| Net Profit Margin | -140.3% | -140.3% | -444.1% | -599.5% | -814.2% | -211.0% | -372.6% | -411.9% | — | — | — |
Return on Capital
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -368.2% | -368.2% | -143.5% | -65.7% | -85.5% | -37.5% | -27.0% | -40.3% | -491.9% | — | — |
| ROA | -44.4% | -44.4% | -49.6% | -26.1% | -40.6% | -23.3% | -16.9% | -26.0% | -135.0% | -128.3% | -86.4% |
| ROIC | -241.1% | -241.1% | -167.7% | -106.9% | -105.2% | -88.9% | -246.7% | — | -450.1% | — | — |
| ROCE | -64.1% | -64.1% | -70.1% | -55.3% | -47.7% | -25.9% | -21.4% | -32.7% | -182.0% | -302.3% | -121.5% |
MGTX Leverage & Debt
Solvency and debt-coverage ratios — lower is generally safer
Net debt stands at $23M ($89M total debt minus $66M cash).
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | — | 1.25 | 0.65 | 0.78 | 0.13 | 0.09 | 0.12 | 0.00 | — | — |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | — | -0.28 | -0.29 | -0.20 | -0.61 | -0.79 | -1.07 | -0.84 | — | — |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | — | — | -18.44 | — | — | — |
| Interest Coverage | -8.69 | -8.69 | -10.14 | -5.34 | -25.21 | -275.25 | -415.60 | -1125.19 | -2336.42 | -739.21 | -788.70 |
MGTX Liquidity & Efficiency
Short-term solvency ratios and asset-utilisation metrics
The current ratio of 0.75x is below 1.0, meaning current liabilities exceed current assets. The current ratio has declined from 2.38x to 0.75x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 0.75 | 0.75 | 2.03 | 2.38 | 1.88 | 2.69 | 5.03 | 5.47 | 4.82 | 0.54 | 3.16 |
| Quick Ratio | 0.75 | 0.75 | 2.03 | 2.38 | 1.88 | 2.69 | 5.03 | 5.47 | 4.82 | 0.54 | 3.16 |
| Cash Ratio | 0.54 | 0.54 | 1.71 | 1.93 | 1.41 | 2.02 | 3.87 | 4.62 | 4.39 | 0.40 | 2.89 |
| Asset Turnover | — | 0.33 | 0.12 | 0.04 | 0.05 | 0.12 | 0.04 | 0.04 | — | — | — |
| Inventory Turnover | — | — | 61.79 | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | 13.45 | 116.57 | 609.72 | 665.41 | 339.02 | 1299.52 | 1019.10 | — | — | — |
MGTX Shareholder Yields
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
MeiraGTx Holdings plc does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business.
Dividends
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
Total Shareholder Return Metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | 1.7% | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — |
| Shares Outstanding | — | $80M | $70M | $56M | $45M | $44M | $38M | $33M | $19M | $9M | $19M |
Peer Comparison
Compare MGTX with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
 MGTXYou | $1B | -8.1 | — | — | 94.0% | -130.2% | -368.2% | -241.1% | — |
 ADVM | $96M | -0.7 | — | — | 100.0% | -13915.9% | -189.8% | -124.2% | — |
 OCGN | $437M | -5.6 | — | — | 45.9% | -1425.7% | -776.9% | -1565.6% | — |
 EDIT | $274M | -1.6 | — | — | 100.0% | -245.2% | -198.1% | — | — |
 CRSP | $5B | -8.4 | — | — | -6537.0% | -16191.4% | -30.2% | -22.3% | — |
 NTLA | $2B | -4.1 | — | — | 76.5% | -651.7% | -53.5% | -44.0% | — |
 BEAM | $4B | -43.9 | — | — | 84.0% | -274.6% | -8.1% | -31.1% | — |
 SGMO | $73M | -0.4 | — | — | 80.8% | -273.1% | -2891.8% | -5405.6% | — |
 ARWR | $12B | -6721.3 | 95.6 | 73.6 | 100.0% | 11.9% | -0.5% | 9.3% | 3.0 |
 IONS | $13B | -31.9 | — | — | 98.3% | -40.5% | -70.7% | -12.8% | — |
 ALNY | $38B | 122.9 | 67.9 | 82.1 | 81.8% | 13.5% | 73.3% | 33.4% | 2.3 |
| Healthcare Median | — | 22.1 | 14.2 | 18.4 | 63.9% | -4.4% | -33.2% | -11.7% | 3.2 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Download Financial Ratios Data
Includes 30+ ratios · 10 years · Updated daily
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MGTX — Frequently Asked Questions
Quick answers to the most common questions about buying MGTX stock.
What is MeiraGTx Holdings plc's P/E ratio?
MeiraGTx Holdings plc's current P/E ratio is -8.1x. This places it at the 50th percentile of its historical range.
What is MeiraGTx Holdings plc's ROE?
MeiraGTx Holdings plc's return on equity (ROE) is -368.2%. The historical average is -157.4%.
Is MGTX stock overvalued?
Based on historical data, MeiraGTx Holdings plc is trading at a P/E of -8.1x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
What are MeiraGTx Holdings plc's profit margins?
MeiraGTx Holdings plc has 94.0% gross margin and -130.2% operating margin.