8-K Announcements
6Apr 2, 2026·SEC
Dec 4, 2025·SEC
Oct 22, 2025·SEC
Palisade Bio, Inc. (PALI) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Palisade Bio, Inc. (PALI) stock price & volume — 10-year historical chart
Palisade Bio, Inc. (PALI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Palisade Bio, Inc. (PALI) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | Mar 23, 2026 | $0.04vs $0.02-100.0% | — |
| Q4 2025 | Nov 10, 2025 | $0.38vs $0.32-18.8% | — |
| Q3 2025 | Aug 11, 2025 | $0.58vs $0.48-20.8% | — |
| Q2 2025 | May 12, 2025 | $0.47vs $0.84+44.0% | — |
Palisade Bio, Inc. (PALI) competitors in Immunology and Inflammation Therapies — business model, growth, and fundamentals comparison
Palisade Bio, Inc. (PALI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Palisade Bio, Inc. (PALI) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 260K | 260K | 15.39K | 0 | 0 | 0 | 250K | 0 | 0 |
| Revenue Growth % | 1500.39% | 0% | -94.08% | -100% | - | - | - | -100% | - |
| Cost of Goods Sold | 0 | -990K | 0 | 146K | 0 | 0 | 0 | 0 | 3K |
| COGS % of Revenue | - | -380.77% | - | - | - | - | - | - | - |
| Gross Profit | 260K▲ 0% | 1.25M▲ 380.8% | 15.39K▼ 98.8% | -146K▼ 1048.4% | 0▲ 100.0% | 0▲ 0% | 250K▲ 0% | 0▼ 100.0% | -3K▲ 0% |
| Gross Margin % | 100% | 480.77% | 100% | - | - | - | 100% | - | - |
| Gross Profit Growth % | 1500.39% | 380.77% | -98.77% | -1048.42% | 100% | - | - | -100% | - |
| Operating Expenses | 13.57M | 8.52M | 8.65M | 9.15M | 41.85M | 15.72M | 13.32M | 14.86M | 18.06M |
| OpEx % of Revenue | 5218.08% | 3276.54% | 56171.24% | - | - | - | 5328% | - | - |
| Selling, General & Admin | 5.18M | 4.37M | 4.44M | 6.05M | 9.31M | 8.76M | 6.2M | 5.8M | 7.86M |
| SG&A % of Revenue | 1993.08% | 1681.92% | 28855.4% | - | - | - | 2480.8% | - | - |
| Research & Development | 8M | 3.96M | 4.06M | 3.1M | 2.43M | 6.55M | 6.89M | 9.06M | 10.19M |
| R&D % of Revenue | 3078.46% | 1523.08% | 26380.41% | - | - | - | 2757.2% | - | - |
| Other Operating Expenses | 0 | 0 | 0 | 0 | 30.12M | 410K | 225K | 0 | 0 |
| Operating Income | -13.21M▲ 0% | -8.26M▲ 37.5% | -8.63M▼ 4.5% | -9.3M▼ 7.7% | -41.85M▼ 350.2% | -15.72M▲ 62.4% | -13.07M▲ 16.9% | -14.86M▼ 13.7% | -18.06M▼ 21.5% |
| Operating Margin % | -5082.69% | -3176.54% | -56073.79% | - | - | - | -5228% | - | - |
| Operating Income Growth % | 34.47% | 37.5% | -4.52% | -7.7% | -350.19% | 62.44% | 16.86% | -13.69% | -21.52% |
| EBITDA | -12.93M | -8.07M | -8.49M | -9.15M | -41.85M | -15.72M | -13.07M | -14.86M | -18.05M |
| EBITDA Margin % | -4971.46% | -3105.08% | -55139.28% | - | - | - | -5226.4% | - | - |
| EBITDA Growth % | 34.82% | 37.54% | -5.14% | -7.81% | -357.35% | 62.44% | 16.87% | -13.7% | -21.52% |
| D&A (Non-Cash Add-back) | 289.21K | 185.8K | 143.86K | 146K | 2K | 3K | 4K | 3K | 3K |
| EBIT | -15.51M | -4.92M | -8.34M | -10.09M | -24.22M | -14.25M | -12.29M | -14.43M | -18.06M |
| Net Interest Income | -88.8K | 71.08K | 58.81K | -235K | -2.4M | 0 | -15K | -12K | -10K |
| Interest Income | 70.27K | 78.78K | 67.73K | 0 | 0 | 13K | 0 | 0 | 0 |
| Interest Expense | 159.07K | 7.7K | 8.92K | 235K | 2.4M | 13K | 15K | 12K | 10K |
| Other Income/Expense | -2.45M | 3.33M | 280.04K | -1.02M | 15.24M | 1.46M | 770K | 421K | 1.27M |
| Pretax Income | -15.67M▲ 0% | -4.92M▲ 68.6% | -8.35M▼ 69.6% | -10.32M▼ 23.6% | -26.62M▼ 157.9% | -14.26M▲ 46.4% | -12.3M▲ 13.7% | -14.44M▼ 17.4% | -16.78M▼ 16.2% |
| Pretax Margin % | -6025.38% | -1894.23% | -54254.9% | - | - | - | -4920% | - | - |
| Income Tax | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
| Net Income | -15.67M▲ 0% | -4.92M▲ 68.6% | -8.35M▼ 69.6% | -10.32M▼ 23.6% | -26.62M▼ 157.9% | -14.26M▲ 46.4% | -12.3M▲ 13.7% | -14.44M▼ 17.4% | -16.78M▼ 16.2% |
| Net Margin % | -6025.38% | -1894.23% | -54254.9% | - | - | - | -4920% | - | - |
| Net Income Growth % | 25.67% | 68.56% | -69.58% | -23.59% | -157.86% | 46.42% | 13.74% | -17.38% | -16.23% |
| Net Income (Continuing) | -15.67M | -4.92M | -8.35M | -10.32M | -26.62M | -14.26M | -12.3M | -14.44M | -16.78M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -71.34▲ 0% | -18.02▲ 74.7% | -35.18▼ 95.2% | -186.00▼ 428.7% | -2546.10▼ 1268.9% | -16.53▲ 99.4% | -27.01▼ 63.4% | -10.19▲ 62.3% | -0.30▲ 97.1% |
| EPS Growth % | 43.43% | 74.74% | -95.23% | -428.71% | -1268.87% | 99.35% | -63.4% | 62.27% | 97.06% |
| EPS (Basic) | -71.59 | -18.02 | -14.78 | -186.00 | -2144.25 | -16.53 | -27.01 | -10.19 | -0.30 |
| Diluted Shares Outstanding | 219.6K | 273.24K | 237.39K | 237.39K | 12.46K | 880.3K | 456.01K | 1.42M | 55.67M |
| Basic Shares Outstanding | 218.84K | 273.24K | 122.41K | 832.3K | 12.41K | 880.1K | 456.01K | 1.42M | 55.67M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
Palisade Bio, Inc. (PALI) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 12.45M | 6.51M | 5.65M | 896K | 11.51M | 14.73M | 13.33M | 10.49M | 134.22M |
| Cash & Short-Term Investments | 11.67M | 5.79M | 5.11M | 729K | 10.49M | 12.38M | 12.43M | 9.82M | 133.38M |
| Cash Only | 6.67M | 5.79M | 5.11M | 713K | 10.49M | 12.38M | 12.43M | 9.82M | 133.38M |
| Short-Term Investments | 5M | 0 | 0 | 16K | 0 | 0 | 0 | 0 | 0 |
| Accounts Receivable | 371.59K | 358K | 21.06K | 0 | 150K | 1.44M | 148K | 24K | 264K |
| Days Sales Outstanding | 521.65 | 502.57 | 499.44 | - | - | - | 216.08 | - | - |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | - |
| Other Current Assets | 0 | 0 | 0 | 100K | 0 | 114K | 112K | 87K | 572K |
| Total Non-Current Assets | 1.44M | 1.18M | 937.01K | 2.12M | 1.01M | 1.03M | 724K | 386K | 123K |
| Property, Plant & Equipment | 172.89K | 90.31K | 242.74K | 280K | 112K | 310K | 208K | 87K | 0 |
| Fixed Asset Turnover | 1.50x | 2.88x | 0.06x | - | - | - | 1.20x | - | - |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 883.46K | 763.54K | 668.94K | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 365.46K | 298.24K | 0 | 0 | 0 | 26K | 0 | 26K | 55K |
| Other Non-Current Assets | 13.85K | 23.96K | 25.34K | 1.84M | 894K | 694K | 516K | 273K | 68K |
| Total Assets | 13.88M▲ 0% | 7.68M▼ 44.7% | 6.58M▼ 14.3% | 3.02M▼ 54.1% | 12.51M▲ 314.4% | 15.76M▲ 26.0% | 14.05M▼ 10.9% | 10.88M▼ 22.6% | 134.34M▲ 1134.8% |
| Asset Turnover | 0.02x | 0.03x | 0.00x | - | - | - | 0.02x | - | - |
| Asset Growth % | -38.58% | -44.65% | -14.32% | -54.15% | 314.44% | 25.98% | -10.85% | -22.57% | 1134.78% |
| Total Current Liabilities | 1.51M | 1.05M | 1.22M | 8.08M | 2.5M | 3.01M | 2.59M | 3.24M | 4.64M |
| Accounts Payable | 875.07K | 832.56K | 824.41K | 2.54M | 1.52M | 1.76M | 698K | 1.1M | 767K |
| Days Payables Outstanding | - | -306.96 | - | 6.34K | - | - | - | - | 93.32K |
| Short-Term Debt | 0 | 0 | 0 | 1.05M | 87K | 88K | 158K | 79K | 71K |
| Deferred Revenue (Current) | 0 | -4.5M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 220.88K | -756.4K | 124.67K | 0 | 511K | 574K | 831K | 0 | 3.8M |
| Current Ratio | 8.22x | 6.19x | 4.61x | 0.11x | 4.61x | 4.89x | 5.15x | 3.24x | 28.95x |
| Quick Ratio | 8.22x | 6.19x | 4.61x | 0.11x | 4.61x | 4.89x | 5.15x | 3.24x | 28.95x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 3.85M | 583.73K | 233.14K | 2.04M | 2.65M | 272K | 153K | 152K | 328K |
| Long-Term Debt | 0 | 535K | 0 | 94K | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 0 | 0 | 148.54K | 112K | 0 | 211K | 90K | 0 | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 3.85M | 48.73K | 84.59K | 1.83M | 2.65M | 61K | 63K | 152K | 328K |
| Total Liabilities | 5.37M | 1.63M | 1.46M | 10.12M | 5.15M | 3.28M | 2.74M | 3.39M | 4.96M |
| Total Debt | 0 | 5.04M | 288.54K | 1.42M | 199K | 404K | 369K | 169K | 71K |
| Net Debt | -6.67M | -749.11K | -4.83M | 708K | -10.3M | -11.98M | -12.06M | -9.65M | -133.31M |
| Debt / Equity | - | 0.83x | 0.06x | - | 0.03x | 0.03x | 0.03x | 0.02x | 0.00x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Interest Coverage | -83.08x | -1072.88x | -967.71x | -39.56x | -17.45x | -1209.31x | -871.33x | -1238.25x | -1805.60x |
| Total Equity | 8.52M▲ 0% | 6.05M▼ 29.0% | 5.13M▼ 15.3% | -7.1M▼ 238.5% | 7.37M▲ 203.7% | 12.48M▲ 69.4% | 11.31M▼ 9.3% | 7.49M▼ 33.8% | 129.38M▲ 1626.9% |
| Equity Growth % | -24.85% | -28.96% | -15.27% | -238.49% | 203.75% | 69.44% | -9.34% | -33.78% | 1626.91% |
| Book Value per Share | 38.78 | 22.14 | 21.59 | -29.90 | 590.95 | 14.18 | 24.81 | 5.29 | 2.32 |
| Total Shareholders' Equity | 8.52M | 6.05M | 5.13M | -7.1M | 7.37M | 12.48M | 11.31M | 7.49M | 129.38M |
| Common Stock | 151.6K | 182.05K | 38.66K | 28K | 3K | 30K | 93K | 27K | 1.59M |
| Retained Earnings | -208.7M | -213.62M | -221.98M | -68.03M | -94.64M | -109.19M | -121.51M | -135.94M | -152.72M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | 2.63K | -413 | -6.19K | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Palisade Bio, Inc. (PALI) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -13.42M | -7.69M | -7.26M | -4.77M | -14.77M | -13.36M | -11.13M | -12.19M | -10.85M |
| Operating CF Margin % | -5160.06% | -2958.62% | -47133.17% | - | - | - | -4453.2% | - | - |
| Operating CF Growth % | 14.09% | 42.66% | 5.68% | 34.29% | -209.84% | 9.56% | 16.67% | -9.52% | 11.04% |
| Net Income | -15.67M | -4.92M | -8.35M | -10.32M | -26.62M | -14.26M | -12.3M | -14.44M | -16.78M |
| Depreciation & Amortization | 289.21K | 185.8K | 143.86K | 3K | 2K | 3K | 4K | 3K | 3K |
| Stock-Based Compensation | 1.77M | 1.09M | 0 | 2.01M | 1.89M | 1.03M | 624K | 652K | 3.96M |
| Deferred Taxes | 0 | 0 | 0 | -38K | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 6.47M | -2.29M | 743.83K | 1.19M | 14.71M | -1.39M | 139K | 199K | 337K |
| Working Capital Changes | -2.15M | -336.88K | 208.28K | 2.39M | -4.76M | 1.25M | 400K | 1.39M | 1.64M |
| Change in Receivables | -249.23K | 80.81K | 272.99K | -59K | 84K | 0 | 0 | 0 | 0 |
| Change in Inventory | -11.75M | 36.99K | 0 | -947K | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | -1.52M | -36.99K | -15.74K | 1.01M | 0 | 399K | -492K | 818K | 624K |
| Cash from Investing | -94.05K | 5M | 0 | -6K | -54K | -10K | -4K | 0 | 0 |
| Capital Expenditures | -94.05K | -1.71K | 0 | -6K | 0 | -10K | -4K | 0 | 0 |
| CapEx % of Revenue | 36.17% | 0.66% | - | - | - | - | 1.6% | - | - |
| Acquisitions | 82.64K | 0 | 0 | 0 | -54K | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | -82.64K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Financing | 4.99M | 1.81M | 6.59M | 1.89M | 24.61M | 15.26M | 11.19M | 9.58M | 134.44M |
| Debt Issued (Net) | -3.75M | -13.77K | 36.43K | 802K | -183K | -790K | -391K | -426K | -320K |
| Equity Issued (Net) | 8.74M | 1.83M | 6.55M | 1.18M | 25.11M | 14.4M | 9.42M | 8.44M | 135.25M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | 0 | 0 | -87K | -317K | 1.65M | 2.16M | 1.57M | -495K |
| Net Change in Cash | -8.52M▲ 0% | -887.83K▲ 89.6% | -672.19K▲ 24.3% | -2.88M▼ 329.0% | 9.78M▲ 439.2% | 1.89M▼ 80.7% | 49K▼ 97.4% | -2.61M▼ 5428.6% | 123.59M▲ 4833.6% |
| Free Cash Flow | -13.51M▲ 0% | -7.69M▲ 43.0% | -7.26M▲ 5.7% | -4.77M▲ 34.2% | -14.77M▼ 209.4% | -13.37M▲ 9.5% | -11.14M▲ 16.7% | -12.19M▼ 9.5% | -10.85M▲ 11.0% |
| FCF Margin % | -5196.23% | -2959.28% | -47133.17% | - | - | - | -4454.8% | - | - |
| FCF Growth % | 14.37% | 43.05% | 5.7% | 34.2% | -209.45% | 9.5% | 16.7% | -9.48% | 11.04% |
| FCF per Share | -61.52 | -28.16 | -30.56 | -20.11 | -1185.35 | -15.19 | -24.42 | -8.61 | -0.19 |
| FCF Conversion (FCF/Net Income) | 0.86x | 1.56x | 0.87x | 0.46x | 0.56x | 0.94x | 0.91x | 0.84x | 0.65x |
| Interest Paid | 0 | 0 | 0 | 0 | 64K | 0 | 0 | 14K | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Palisade Bio, Inc. (PALI) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -258.62% | -157.88% | -67.63% | -149.47% | - | -20012.03% | -143.72% | -103.4% | -153.55% | -24.52% |
| Return on Invested Capital (ROIC) | -377.18% | -1178.64% | -173.49% | -231.21% | - | - | - | - | - | - |
| Gross Margin | 100% | 100% | 480.77% | 100% | - | - | - | 100% | - | - |
| Net Margin | -129724.24% | -6025.38% | -1894.23% | -54254.9% | - | - | - | -4920% | - | - |
| Debt / Equity | 0.33x | - | 0.83x | 0.06x | - | 0.03x | 0.03x | 0.03x | 0.02x | 0.00x |
| Interest Coverage | -17.67x | -83.08x | -1072.88x | -967.71x | -39.56x | -17.45x | -1209.31x | -871.33x | -1238.25x | -1805.60x |
| FCF Conversion | 0.74x | 0.86x | 1.56x | 0.87x | 0.46x | 0.56x | 0.94x | 0.91x | 0.84x | 0.65x |
| Revenue Growth | 55.96% | 1500.39% | 0% | -94.08% | -100% | - | - | - | -100% | - |
Palisade Bio, Inc. (PALI) SEC filings — annual & quarterly reports (10-K, 10-Q)
Apr 2, 2026·SEC
Dec 4, 2025·SEC
Oct 22, 2025·SEC
Palisade Bio, Inc. (PALI) stock FAQ — growth, dividends, profitability & financials explained
Palisade Bio, Inc. (PALI) grew revenue by 0.0% over the past year. Growth has been modest.
Palisade Bio, Inc. (PALI) reported a net loss of $16.8M for fiscal year 2025.
Palisade Bio, Inc. (PALI) has a return on equity (ROE) of -24.5%. Negative ROE indicates the company is unprofitable.
Palisade Bio, Inc. (PALI) had negative free cash flow of $10.8M in fiscal year 2025, likely due to heavy capital investments.
Palisade Bio, Inc. (PALI) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates