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PCVX logoVaxcyte, Inc.(PCVX)Earnings, Financials & Key Ratios

PCVX•NASDAQ
$57.10
$8.24B mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutVaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine that is in Phase 1/2 clinical trials to treat invasive pneumococcal disease and pneumonia. The company also develops VAX-XP to protect against emerging strains and address antibiotic resistance; VAX-A1, a conjugate vaccine candidate designed to treat Group A Strep; and VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.Show more
  • Revenue$0
  • EBITDA-$899M-62.3%
  • Net Income-$767M-65.2%
  • EPS (Diluted)-5.63-48.2%
  • ROE-25.59%-25.4%
  • ROIC-24.18%-9.3%
  • Debt/Equity0.09+296.1%
Technical→

PCVX Key Insights

Vaxcyte, Inc. (PCVX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 80 (top 20%)

✗Weaknesses

  • ✗Profits declining 53.8% over 5 years
  • ✗Weak Piotroski F-Score: 1/9
  • ✗Shares diluted 11.6% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

PCVX Price & Volume

Vaxcyte, Inc. (PCVX) stock price & volume — 10-year historical chart

Loading chart...

PCVX Growth Metrics

Vaxcyte, Inc. (PCVX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-85.73%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-68.46%

Return on Capital

10 Years-47.03%
5 Years-33.1%
3 Years-32.11%
Last Year-29.74%

PCVX Recent Earnings

Vaxcyte, Inc. (PCVX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (33%)
Q1 2026Latest
Feb 24, 2026
EPS
$1.80
Est $1.53
-17.7%
Revenue
—
Est $19M
Q4 2025
Nov 4, 2025
EPS
$1.56
Est $1.27
-22.8%
Revenue
—
Q3 2025
Aug 6, 2025
EPS
$1.22
Est $1.12
-8.9%
Revenue
—
Q2 2025
May 7, 2025
EPS
$1.04
Est $1.02
-2.0%
Revenue
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q1 2026LatestFeb 24, 2026
$1.80vs $1.53-17.7%
—vs $19M
Q4 2025Nov 4, 2025
$1.56vs $1.27-22.8%
—
Q3 2025Aug 6, 2025
$1.22vs $1.12-8.9%
—
Q2 2025May 7, 2025
$1.04vs $1.02-2.0%
—
Based on last 12 quarters of dataView full earnings history →

PCVX Peer Comparison

Vaxcyte, Inc. (PCVX) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
PFE logoPFEPfizer Inc.Direct Competitor150.77B26.5119.49-1.65%11.83%8.34%0.78
MRK logoMRKMerck & Co., Inc.Direct Competitor280.48B113.5615.601.18%28.12%36.14%0.96
GSK logoGSKGSK plcDirect Competitor101.62B50.536.694.11%19.19%31.48%1.11
SNY logoSNYSanofiDirect Competitor105.71B43.7718.375.49%16.72%10.78%0.30
BNTX logoBNTXBioNTech SEProduct Competitor23.94B95.26-18.000.2%-39.6%-6.03%0.01
NVAX logoNVAXNovavax, Inc.Product Competitor1.53B9.363.6964.69%-14.73%
DVAX logoDVAXDynavax Technologies CorporationProduct Competitor1.82B15.5077.5019.36%-13.13%-8.13%0.43
IBRX logoIBRXImmunityBio, Inc.Product Competitor8.25B8.38-13.5222.71%-422.28%

Compare PCVX vs Peers

Vaxcyte, Inc. (PCVX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PFE

Most directly comparable listed peer for PCVX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare PCVX against a more recognizable public peer.

Peer Set

Compare Top 5

vs PFE, MRK, GSK, SNY

PCVX Income Statement

Vaxcyte, Inc. (PCVX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue0000000000
Revenue Growth %----------
Cost of Goods Sold01.04M1.23M1.41M000000
COGS % of Revenue----------
Gross Profit
0▲ 0%
-1.04M▲ 0%
-1.23M▼ 18.8%
-1.41M▼ 14.0%
0▲ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
Gross Margin %----------
Gross Profit Growth %---18.8%-14.04%100%-----
Operating Expenses17.4M35.53M52.92M88.18M103.67M232.26M468.04M569.55M923.67M1.09B
OpEx % of Revenue----------
Selling, General & Admin5.05M5.39M7.31M14.61M25.26M39.81M60.7M92.9M129.37M129.78M
SG&A % of Revenue----------
Research & Development12.79M30.14M45.61M73.56M78.41M169.45M332.34M476.64M794.31M958.95M
R&D % of Revenue----------
Other Operating Expenses05.18M00023M75M000
Operating Income
-17.83M▲ 0%
-35.53M▼ 99.3%
-54.15M▼ 52.4%
-89.58M▼ 65.4%
-103.67M▼ 15.7%
-232.26M▼ 124.0%
-468.04M▼ 101.5%
-569.55M▼ 21.7%
-923.67M▼ 62.2%
-1.09B▲ 0%
Operating Margin %----------
Operating Income Growth %--99.25%-52.4%-65.42%-15.73%-124.03%-101.52%-21.69%-62.18%-
EBITDA-17.21M-34.5M-52.92M-88.18M-100.21M-222.8M-457.87M-553.7M-898.82M-1.07B
EBITDA Margin %----------
EBITDA Growth %--100.46%-53.41%-66.62%-13.65%-122.33%-105.5%-20.93%-62.33%-72.87%
D&A (Non-Cash Add-back)625K1.04M1.23M1.41M3.46M9.45M10.17M15.85M24.86M19.99M
EBIT-17.83M-29.41M-50.23M-89.21M-100.07M-223.48M-402.27M-463.93M-766.63M-625.91M
Net Interest Income0828K592K237K337K8.35M62.91M109.99M119.72M86.78M
Interest Income164K903K632K244K344K8.36M62.91M109.99M119.72M113.39M
Interest Expense075K40K7K7K2K0000
Other Income/Expense595K6.05M3.88M364K3.59M8.77M65.78M105.62M157.05M142.2M
Pretax Income
-17.24M▲ 0%
-29.48M▼ 71.0%
-50.27M▼ 70.5%
-89.22M▼ 77.5%
-100.08M▼ 12.2%
-223.49M▼ 123.3%
-402.27M▼ 80.0%
-463.93M▼ 15.3%
-766.63M▼ 65.2%
-946.53M▲ 0%
Pretax Margin %----------
Income Tax0000000000
Effective Tax Rate %0%0%0%0%0%0%0%0%0%0%
Net Income
-17.24M▲ 0%
-29.48M▼ 71.0%
-50.27M▼ 70.5%
-89.22M▼ 77.5%
-100.08M▼ 12.2%
-223.49M▼ 123.3%
-402.27M▼ 80.0%
-463.93M▼ 15.3%
-766.63M▼ 65.2%
-946.53M▲ 0%
Net Margin %----------
Net Income Growth %--71.05%-70.51%-77.46%-12.17%-123.31%-80%-15.33%-65.25%-85.73%
Net Income (Continuing)-17.24M-29.48M-50.27M-89.22M-100.08M-223.49M-402.27M-463.93M-766.63M-946.53M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-4.83▲ 0%
-8.12▼ 68.1%
-14.10▼ 73.6%
-2.97▲ 78.9%
-1.93▲ 35.0%
-3.44▼ 78.2%
-4.14▼ 20.3%
-3.80▲ 8.2%
-5.63▼ 48.2%
-6.78▲ 0%
EPS Growth %--68.12%-73.65%78.94%35.02%-78.24%-20.35%8.21%-48.16%-68.46%
EPS (Basic)-4.84-8.12-14.10-2.97-1.93-3.44-4.14-3.80-5.63-
Diluted Shares Outstanding3.57M3.63M3.8M29.55M51.92M64.88M97.16M122M136.09M139.51M
Basic Shares Outstanding3.56M3.63M3.79M29.55M51.92M64.88M97.16M122M136.09M139.51M
Dividend Payout Ratio----------

PCVX Balance Sheet

Vaxcyte, Inc. (PCVX) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets36.35M66.67M61.72M389M256.35M942.55M1.1B1.79B1.63B1.81B
Cash & Short-Term Investments36.14M66.09M58.98M386.2M245.97M931.38M1.08B1.75B1.56B1.74B
Cash Only36.14M66.09M58.98M386.2M68.98M834.66M397.45M387.88M173.96M260.84M
Short-Term Investments0000176.99M96.72M682.78M1.36B1.39B1.48B
Accounts Receivable0000003.61M20.66M46.56M0
Days Sales Outstanding----------
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets0000005.96M20.11M2.8M76.31M
Total Non-Current Assets3.28M4.13M3.98M3.82M67.99M63.62M311.96M1.72B1.42B1.53B
Property, Plant & Equipment2.97M3.41M3.39M3.27M35.91M31.65M110.62M270.15M491.72M373.8M
Fixed Asset Turnover---------0.00x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments000027.12M26.55M162.68M1.39B883.13M4.01B
Other Non-Current Assets311K723K584K550K4.96M5.43M38.66M65.68M508K360.8M
Total Assets
39.63M▲ 0%
70.8M▲ 78.7%
65.7M▼ 7.2%
392.83M▲ 497.9%
324.34M▼ 17.4%
1.01B▲ 210.2%
1.41B▲ 39.9%
3.51B▲ 149.4%
3.05B▼ 13.3%
3.35B▲ 0%
Asset Turnover---------0.00x
Asset Growth %-78.65%-7.21%497.93%-17.43%210.23%39.93%149.4%-13.25%33.32%
Total Current Liabilities4.26M6.71M11.05M46.86M28.72M40.52M145.34M140.18M205.75M242.08M
Accounts Payable1.81M2.83M3.38M29.79M6.76M9.79M14.59M48.45M70.9M63.06M
Days Payables Outstanding-996.091K7.74K------
Short-Term Debt000000006.12M6.08M
Deferred Revenue (Current)0-297K00000000
Other Current Liabilities850K2.4M433K298K3.46M1.18M11.06M20.55M105.72M236M
Current Ratio8.53x9.93x5.58x8.30x8.93x23.26x7.54x12.75x7.91x7.91x
Quick Ratio8.53x9.93x5.58x8.30x8.93x23.26x7.54x12.75x7.91x7.91x
Cash Conversion Cycle----------
Total Non-Current Liabilities4.43M121.82M161.02M122K11.6M12.04M22.11M65.32M154.7M110.21M
Long-Term Debt3.76M0000000111.36M110.21M
Capital Lease Obligations458K161K0011.51M12.03M22.11M65.22M111.36M269.57M
Deferred Tax Liabilities0000000043.25M43.25M
Other Non-Current Liabilities212K121.66M161.02M122K96K9K0100K-111.26M-111.26M
Total Liabilities8.69M128.53M172.07M46.98M40.32M52.56M167.45M205.5M360.45M352.29M
Total Debt4.5M458K161K016.78M17.94M29.22M71.11M228.84M116.3M
Net Debt-31.64M-65.63M-58.81M-386.2M-52.2M-816.72M-368.23M-316.77M54.88M-144.55M
Debt / Equity0.15x---0.06x0.02x0.02x0.02x0.09x0.09x
Debt / EBITDA----------0.11x
Net Debt / EBITDA---------0.14x
Interest Coverage--392.13x-1255.85x-12744.29x-14295.71x-111741.50x----
Total Equity
30.94M▲ 0%
-57.73M▼ 286.6%
-106.37M▼ 84.3%
345.84M▲ 425.1%
284.02M▼ 17.9%
953.61M▲ 235.8%
1.24B▲ 30.1%
3.31B▲ 166.5%
2.69B▼ 18.8%
3B▲ 0%
Equity Growth %--286.59%-84.27%425.12%-17.88%235.76%30.08%166.5%-18.76%14.15%
Book Value per Share8.68-15.90-28.0311.715.4714.7012.7727.1019.7321.48
Total Shareholders' Equity30.94M-57.73M-106.37M345.84M284.02M953.61M1.24B3.31B2.69B3B
Common Stock6K6K7K54K56K82K98K128K134K147K
Retained Earnings-29.59M-59.07M-109.35M-198.56M-298.64M-522.13M-924.39M-1.39B-2.15B-2.48B
Treasury Stock0000000000
Accumulated OCI0-1.75M00-241K-361K179K-3.87M1.59M-6.83M
Minority Interest0000000000

PCVX Cash Flow Statement

Vaxcyte, Inc. (PCVX) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations-14.96K-30.47M-47.15M-46.63M-121.39M-170.6M-296.79M-452.63M-655.58M-655.58M
Operating CF Margin %----------
Operating CF Growth %--203508.9%-54.75%1.1%-160.34%-40.53%-73.97%-52.51%-44.84%-306.46%
Net Income-17.24K-29.48M-50.27M-89.22M-100.08M-223.49M-402.27M-463.93M-766.63M-946.53M
Depreciation & Amortization6251.04M1.23M1.41M3.46M9.45M10.17M15.85M24.86M25.84M
Stock-Based Compensation390749K1.19M5.43M10.73M23.65M48.76M84.82M138.84M146.19M
Deferred Taxes051K0301K000000
Other Non-Cash Items260-4.71M-3.2M179K1.5M7.05M-34.77M-34.47M-72.56M-64.85M
Working Capital Changes1K1.9M3.91M35.27M-37.01M12.74M81.32M-54.9M19.91M69.42M
Change in Receivables01.27M868K0000000
Change in Inventory0-1.19M00000000
Change in Payables01.27M868K26.1M-12.47M2.9M11.22M34.58M19.91M48.8M
Cash from Investing-1.12K-1.77M-1.2M-1.1M-212.31M74.58M-773.31M-2.01B437.35M80.63M
Capital Expenditures-1.22K-1.77M-1.2M-1.16M-6.55M-5.84M-67.88M-22.43M-13.71M10.93M
CapEx % of Revenue----------
Acquisitions01K050K000000
Investments----------
Other Investing1061K0026K00-96.73M-43.26M-55.95M
Cash from Financing43.86K62.19M41.57M374.87M17.8M861.55M639.81M2.45B2.01M602.84M
Debt Issued (Net)-188K-283K-278K-61K000000
Equity Issued (Net)062.34M42.5M373.89M13.9M856.48M636.04M2.44B00
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing231.86K128K-655K1.04M3.9M5.07M3.77M12.85M2.01M602.84M
Net Change in Cash
27.78K▲ 0%
29.95M▲ 107715.0%
-7.11M▼ 123.8%
327.22M▲ 4699.7%
-316.34M▼ 196.7%
765.67M▲ 342.0%
-436.97M▼ 157.1%
-9.36M▲ 97.9%
-213.77M▼ 2184.1%
-85.86M▲ 0%
Free Cash Flow
-16.18K▲ 0%
-32.24M▼ 199096.8%
-48.34M▼ 49.9%
-47.78M▲ 1.2%
-127.95M▼ 167.8%
-176.44M▼ 37.9%
-364.67M▼ 106.7%
-475.05M▼ 30.3%
-669.29M▼ 40.9%
-759M▲ 0%
FCF Margin %----------
FCF Growth %--199096.79%-49.94%1.15%-167.77%-37.9%-106.68%-30.27%-40.89%-26.5%
FCF per Share-0.00-8.88-12.74-1.62-2.46-2.72-3.75-3.89-4.92-4.92
FCF Conversion (FCF/Net Income)0.00x1.03x0.94x0.52x1.21x0.76x0.74x0.98x0.86x0.80x
Interest Paid0040K07K2K0000
Taxes Paid0000000000

PCVX Key Ratios

Vaxcyte, Inc. (PCVX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric20182019202020212022202320242025TTM
Return on Equity (ROE)---74.51%-31.78%-36.12%-36.67%-20.41%-25.59%-32.51%
Return on Invested Capital (ROIC)----81.22%-94.49%-69.57%-22.13%-24.18%-24.18%
Debt / Equity---0.06x0.02x0.02x0.02x0.09x0.09x
Interest Coverage-392.13x-1255.85x-12744.29x-14295.71x-111741.50x----
FCF Conversion1.03x0.94x0.52x1.21x0.76x0.74x0.98x0.86x0.80x

PCVX SEC Filings & Documents

Vaxcyte, Inc. (PCVX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

Feb 24, 2026·SEC

Material company update

Feb 24, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 24, 2026·SEC

FY 2025

Feb 25, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 6, 2025·SEC

PCVX Frequently Asked Questions

Vaxcyte, Inc. (PCVX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Vaxcyte, Inc. (PCVX) grew revenue by 0.0% over the past year. Growth has been modest.

Vaxcyte, Inc. (PCVX) reported a net loss of $946.5M for fiscal year 2025.

Dividend & Returns

Vaxcyte, Inc. (PCVX) has a return on equity (ROE) of -25.6%. Negative ROE indicates the company is unprofitable.

Vaxcyte, Inc. (PCVX) had negative free cash flow of $759.0M in fiscal year 2025, likely due to heavy capital investments.

Explore More PCVX

Vaxcyte, Inc. (PCVX) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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