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PCVXVaxcyte, Inc.
$51.44$7.4B
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PCVX logoVaxcyte, Inc.(PCVX)Earnings, Financials & Key Ratios

PCVX•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutVaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine that is in Phase 1/2 clinical trials to treat invasive pneumococcal disease and pneumonia. The company also develops VAX-XP to protect against emerging strains and address antibiotic resistance; VAX-A1, a conjugate vaccine candidate designed to treat Group A Strep; and VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.Show more
  • Revenue$0
  • EBITDA-$899M-62.3%
  • Net Income-$767M-65.2%
  • EPS (Diluted)-5.63-48.2%
  • ROE-25.59%-25.4%

PCVX Key Insights

Vaxcyte, Inc. (PCVX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free

✗Weaknesses

  • ✗Profits declining 53.8% over 5 years
  • ✗Weak Piotroski F-Score: 1/9
  • ✗Shares diluted 11.6% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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PCVX Price & Volume

Vaxcyte, Inc. (PCVX) stock price & volume — 10-year historical chart

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PCVX Growth Metrics

Vaxcyte, Inc. (PCVX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-85.73%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-68.46%

Return on Capital

10 Years-47.03%
5 Years-33.1%
3 Years-32.11%
Last Year-29.74%

PCVX Recent Earnings

Vaxcyte, Inc. (PCVX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/12 qtrs (25%)
Q2 2026Latest
May 6, 2026
Metric
Actual
Est
EPS
$2.30-29.7%
$1.77
Rev
—
$13M
Q1 2026
Feb 24, 2026
Metric
Actual
Est
EPS
$1.80-17.7%
$1.53
Rev
—
$19M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$1.56-22.8%
$1.27
Rev
—
—
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$1.22-8.9%
$1.12
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$2.30vs $1.77-29.7%
—vs $13M
Q1 2026Feb 24, 2026
$1.80vs $1.53-17.7%
—vs $19M
Q4 2025Nov 4, 2025
$1.56vs $1.27-22.8%
—
Q3 2025Aug 6, 2025
$1.22vs $1.12-8.9%
—
Based on last 12 quarters of dataView full earnings history →

PCVX Peer Comparison

Vaxcyte, Inc. (PCVX) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
PFE logoPFEPfizer Inc.Direct Competitor143.46B25.2218.54-1.65%11.83%8.34%0.78
MRK logoMRKMerck & Co., Inc.Direct Competitor281.25B113.8715.641.18%28.12%36.14%0.96
GSK logoGSKGSK plcDirect Competitor101.9B50.676.864.11%19.19%31.48%1.11
SNY logoSNYSanofiDirect Competitor102.35B42.3818.145.49%16.72%10.78%0.30
BNTX logoBNTXBioNTech SEProduct Competitor22.98B90.89-17.510.2%-39.6%-6.03%0.01
NVAX logoNVAXNovavax, Inc.Product Competitor1.5B9.133.5964.69%-14.73%
DVAX logoDVAXDynavax Technologies CorporationProduct Competitor1.82B15.5077.5019.36%-13.13%-8.13%0.43
IBRX logoIBRXImmunityBio, Inc.Product Competitor7.71B7.36-19.376.68%-6.06%

Compare PCVX vs Peers

Vaxcyte, Inc. (PCVX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PFE

Most directly comparable listed peer for PCVX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare PCVX against a more recognizable public peer.

Peer Set

Compare Top 5

vs PFE, MRK, GSK, SNY

PCVX Income Statement

Vaxcyte, Inc. (PCVX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0000000000
Revenue Growth %
----------
Cost of Goods Sold
01.04M1.23M1.41M000000
COGS % of Revenue
----------
Gross Profit
0▲ 0%
-1.04M▲ 0%
-1.23M▼ 18.8%
-1.41M▼ 14.0%
0▲ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
Gross Margin %
----------
Gross Profit Growth %
---18.8%-14.04%100%-----
Operating Expenses
17.4M35.53M52.92M88.18M103.67M232.26M468.04M569.55M923.67M1.09B
OpEx % of Revenue
----------
Selling, General & Admin
5.05M5.39M7.31M14.61M25.26M39.81M60.7M92.9M129.37M129.78M
SG&A % of Revenue
----------
Research & Development
12.79M30.14M45.61M73.56M78.41M169.45M332.34M476.64M794.31M958.95M
R&D % of Revenue
----------
Other Operating Expenses
05.18M00023M75M000
Operating Income
-17.83M▲ 0%
-35.53M▼ 99.3%
-54.15M▼ 52.4%
-89.58M▼ 65.4%
-103.67M▼ 15.7%
-232.26M▼ 124.0%
-468.04M▼ 101.5%
-569.55M▼ 21.7%
-923.67M▼ 62.2%
-1.09B▲ 0%
Operating Margin %
----------
Operating Income Growth %
--99.25%-52.4%-65.42%-15.73%-124.03%-101.52%-21.69%-62.18%-
EBITDA
-17.21M-34.5M-52.92M-88.18M-100.21M-222.8M-457.87M-553.7M-898.82M-1.07B
EBITDA Margin %
----------
EBITDA Growth %
--100.46%-53.41%-66.62%-13.65%-122.33%-105.5%-20.93%-62.33%-72.87%
D&A (Non-Cash Add-back)
625K1.04M1.23M1.41M3.46M9.45M10.17M15.85M24.86M19.99M
EBIT
-17.83M-29.41M-50.23M-89.21M-100.07M-223.48M-402.27M-463.93M-766.63M-625.91M
Net Interest Income
0828K592K237K337K8.35M62.91M109.99M119.72M86.78M
Interest Income
164K903K632K244K344K8.36M62.91M109.99M119.72M113.39M
Interest Expense
075K40K7K7K2K0000
Other Income/Expense
595K6.05M3.88M364K3.59M8.77M65.78M105.62M157.05M142.2M
Pretax Income
-17.24M▲ 0%
-29.48M▼ 71.0%
-50.27M▼ 70.5%
-89.22M▼ 77.5%
-100.08M▼ 12.2%
-223.49M▼ 123.3%
-402.27M▼ 80.0%
-463.93M▼ 15.3%
-766.63M▼ 65.2%
-946.53M▲ 0%
Pretax Margin %
----------
Income Tax
0000000000
Effective Tax Rate %
0%0%0%0%0%0%0%0%0%0%
Net Income
-17.24M▲ 0%
-29.48M▼ 71.0%
-50.27M▼ 70.5%
-89.22M▼ 77.5%
-100.08M▼ 12.2%
-223.49M▼ 123.3%
-402.27M▼ 80.0%
-463.93M▼ 15.3%
-766.63M▼ 65.2%
-946.53M▲ 0%
Net Margin %
----------
Net Income Growth %
--71.05%-70.51%-77.46%-12.17%-123.31%-80%-15.33%-65.25%-85.73%
Net Income (Continuing)
-17.24M-29.48M-50.27M-89.22M-100.08M-223.49M-402.27M-463.93M-766.63M-946.53M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-4.83▲ 0%
-8.12▼ 68.1%
-14.10▼ 73.6%
-2.97▲ 78.9%
-1.93▲ 35.0%
-3.44▼ 78.2%
-4.14▼ 20.3%
-3.80▲ 8.2%
-5.63▼ 48.2%
-6.78▲ 0%
EPS Growth %
--68.12%-73.65%78.94%35.02%-78.24%-20.35%8.21%-48.16%-68.46%
EPS (Basic)
-4.84-8.12-14.10-2.97-1.93-3.44-4.14-3.80-5.63-
Diluted Shares Outstanding
3.57M3.63M3.8M29.55M51.92M64.88M97.16M122M136.09M139.51M
Basic Shares Outstanding
3.56M3.63M3.79M29.55M51.92M64.88M97.16M122M136.09M139.51M
Dividend Payout Ratio
----------

PCVX Balance Sheet

Vaxcyte, Inc. (PCVX) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
36.35M66.67M61.72M389M256.35M942.55M1.1B1.79B1.63B1.81B
Cash & Short-Term Investments
36.14M66.09M58.98M386.2M245.97M931.38M1.08B1.75B1.56B1.74B
Cash Only
36.14M66.09M58.98M386.2M68.98M834.66M397.45M387.88M173.96M260.84M
Short-Term Investments
0000176.99M96.72M682.78M1.36B1.39B1.48B
Accounts Receivable
0000003.61M20.66M46.56M0
Days Sales Outstanding
----------
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
0000005.96M20.11M2.8M76.31M
Total Non-Current Assets
3.28M4.13M3.98M3.82M67.99M63.62M311.96M1.72B1.42B1.53B
Property, Plant & Equipment
2.97M3.41M3.39M3.27M35.91M31.65M110.62M270.15M491.72M373.8M
Fixed Asset Turnover
---------0.00x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
000027.12M26.55M162.68M1.39B883.13M4.01B
Other Non-Current Assets
311K723K584K550K4.96M5.43M38.66M65.68M508K157M
Total Assets
39.63M▲ 0%
70.8M▲ 78.7%
65.7M▼ 7.2%
392.83M▲ 497.9%
324.34M▼ 17.4%
1.01B▲ 210.2%
1.41B▲ 39.9%
3.51B▲ 149.4%
3.05B▼ 13.3%
3.35B▲ 0%
Asset Turnover
---------0.00x
Asset Growth %
-78.65%-7.21%497.93%-17.43%210.23%39.93%149.4%-13.25%33.32%
Total Current Liabilities
4.26M6.71M11.05M46.86M28.72M40.52M145.34M140.18M205.75M242.08M
Accounts Payable
1.81M2.83M3.38M29.79M6.76M9.79M14.59M48.45M70.9M63.06M
Days Payables Outstanding
-996.091K7.74K------
Short-Term Debt
000000006.12M6.08M
Deferred Revenue (Current)
0-297K00000000
Other Current Liabilities
850K2.4M433K298K3.46M1.18M11.06M20.55M105.72M172.94M
Current Ratio
8.53x9.93x5.58x8.30x8.93x23.26x7.54x12.75x7.91x7.49x
Quick Ratio
8.53x9.93x5.58x8.30x8.93x23.26x7.54x12.75x7.91x7.49x
Cash Conversion Cycle
----------
Total Non-Current Liabilities
4.43M121.82M161.02M122K11.6M12.04M22.11M65.32M154.7M110.21M
Long-Term Debt
3.76M0000000111.36M110.21M
Capital Lease Obligations
458K161K0011.51M12.03M22.11M65.22M111.36M269.57M
Deferred Tax Liabilities
0000000043.25M43.25M
Other Non-Current Liabilities
212K121.66M161.02M122K96K9K0100K-111.26M0
Total Liabilities
8.69M128.53M172.07M46.98M40.32M52.56M167.45M205.5M360.45M352.29M
Total Debt
4.5M458K161K016.78M17.94M29.22M71.11M228.84M116.3M
Net Debt
-31.64M-65.63M-58.81M-386.2M-52.2M-816.72M-368.23M-316.77M54.88M-144.55M
Debt / Equity
0.15x---0.06x0.02x0.02x0.02x0.09x0.04x
Debt / EBITDA
----------0.11x
Net Debt / EBITDA
---------0.14x
Interest Coverage
--392.13x-1255.85x-12744.29x-14295.71x-111741.50x----
Total Equity
30.94M▲ 0%
-57.73M▼ 286.6%
-106.37M▼ 84.3%
345.84M▲ 425.1%
284.02M▼ 17.9%
953.61M▲ 235.8%
1.24B▲ 30.1%
3.31B▲ 166.5%
2.69B▼ 18.8%
3B▲ 0%
Equity Growth %
--286.59%-84.27%425.12%-17.88%235.76%30.08%166.5%-18.76%14.15%
Book Value per Share
8.68-15.90-28.0311.715.4714.7012.7727.1019.7321.48
Total Shareholders' Equity
30.94M-57.73M-106.37M345.84M284.02M953.61M1.24B3.31B2.69B3B
Common Stock
6K6K7K54K56K82K98K128K134K147K
Retained Earnings
-29.59M-59.07M-109.35M-198.56M-298.64M-522.13M-924.39M-1.39B-2.15B-2.48B
Treasury Stock
0000000000
Accumulated OCI
0-1.75M00-241K-361K179K-3.87M1.59M-6.83M
Minority Interest
0000000000

PCVX Cash Flow Statement

Vaxcyte, Inc. (PCVX) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-14.96K-30.47M-47.15M-46.63M-121.39M-170.6M-296.79M-452.63M-655.58M-769.93M
Operating CF Margin %
----------
Operating CF Growth %
--203508.9%-54.75%1.1%-160.34%-40.53%-73.97%-52.51%-44.84%-306.46%
Net Income
-17.24K-29.48M-50.27M-89.22M-100.08M-223.49M-402.27M-463.93M-766.63M-946.53M
Depreciation & Amortization
6251.04M1.23M1.41M3.46M9.45M10.17M15.85M24.86M25.84M
Stock-Based Compensation
390749K1.19M5.43M10.73M23.65M48.76M84.82M138.84M108.23M
Deferred Taxes
051K0301K000000
Other Non-Cash Items
260-4.71M-3.2M179K1.5M7.05M-34.77M-34.47M-72.56M-23.98M
Working Capital Changes
1K1.9M3.91M35.27M-37.01M12.74M81.32M-54.9M19.91M66.51M
Change in Receivables
01.27M868K0000000
Change in Inventory
0-1.19M00000000
Change in Payables
01.27M868K26.1M-12.47M2.9M11.22M34.58M19.91M48.8M
Cash from Investing
-1.12K-1.77M-1.2M-1.1M-212.31M74.58M-773.31M-2.01B437.35M80.63M
Capital Expenditures
-1.22K-1.77M-1.2M-1.16M-6.55M-5.84M-67.88M-22.43M-13.71M-1.76M
CapEx % of Revenue
----------
Acquisitions
01K050K000000
Investments
----------
Other Investing
1061K0026K00-96.73M-43.26M-43.26M
Cash from Financing
43.86K62.19M41.57M374.87M17.8M861.55M639.81M2.45B2.01M602.84M
Debt Issued (Net)
-188K-283K-278K-61K000000
Equity Issued (Net)
062.34M42.5M373.89M13.9M856.48M636.04M2.44B0610.88M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
231.86K128K-655K1.04M3.9M5.07M3.77M12.85M2.01M-8.04M
Net Change in Cash
27.78K▲ 0%
29.95M▲ 107715.0%
-7.11M▼ 123.8%
327.22M▲ 4699.7%
-316.34M▼ 196.7%
765.67M▲ 342.0%
-436.97M▼ 157.1%
-9.36M▲ 97.9%
-213.77M▼ 2184.1%
-85.86M▲ 0%
Free Cash Flow
-16.18K▲ 0%
-32.24M▼ 199096.8%
-48.34M▼ 49.9%
-47.78M▲ 1.2%
-127.95M▼ 167.8%
-176.44M▼ 37.9%
-364.67M▼ 106.7%
-475.05M▼ 30.3%
-669.29M▼ 40.9%
-771.68M▲ 0%
FCF Margin %
----------
FCF Growth %
--199096.79%-49.94%1.15%-167.77%-37.9%-106.68%-30.27%-40.89%-28.61%
FCF per Share
-0.00-8.88-12.74-1.62-2.46-2.72-3.75-3.89-4.92-5.53
FCF Conversion (FCF/Net Income)
0.00x1.03x0.94x0.52x1.21x0.76x0.74x0.98x0.86x0.82x
Interest Paid
0040K07K2K0000
Taxes Paid
0000000000

PCVX Key Ratios

Vaxcyte, Inc. (PCVX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric20182019202020212022202320242025TTM
Return on Equity (ROE)
---74.51%-31.78%-36.12%-36.67%-20.41%-25.59%-32.51%
Return on Invested Capital (ROIC)
----81.22%-94.49%-69.57%-22.13%-24.18%-29.32%
Debt / Equity
---0.06x0.02x0.02x0.02x0.09x0.04x
Interest Coverage
-392.13x-1255.85x-12744.29x-14295.71x-111741.50x----
FCF Conversion
1.03x0.94x0.52x1.21x0.76x0.74x0.98x0.86x0.82x
Related:PCVX Dividend History·PCVX Revenue History·PCVX Price History·PCVX P/E History·PCVX Financial Ratios·PCVX Institutional Holders

PCVX SEC Filings & Documents

Vaxcyte, Inc. (PCVX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 6, 2026·SEC

Material company update

Feb 24, 2026·SEC

Material company update

Feb 24, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 24, 2026·SEC

FY 2025

Feb 25, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 6, 2025·SEC

PCVX Frequently Asked Questions

Vaxcyte, Inc. (PCVX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Vaxcyte, Inc. (PCVX) grew revenue by 0.0% over the past year. Growth has been modest.

Vaxcyte, Inc. (PCVX) reported a net loss of $946.5M for fiscal year 2025.

Dividend & Returns

Vaxcyte, Inc. (PCVX) has a return on equity (ROE) of -25.6%. Negative ROE indicates the company is unprofitable.

Vaxcyte, Inc. (PCVX) had negative free cash flow of $771.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in PCVX back in 2017?

Total return calculator · dividends reinvested · 9+ years of data

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