Personalis, Inc. (PSNL) Revenue History
Annual and quarterly revenue from 2017 to 2025
Compound Annual Growth Rate (CAGR)
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PSNL Revenue Growth
PSNL Revenue Analysis (2017–2025)
As of May 8, 2026, Personalis, Inc. (PSNL) generated trailing twelve-month (TTM) revenue of $49.0 million, reflecting significant decline in growth of -100.0% year-over-year. The most recent quarter (Q1 2026) recorded $0 in revenue, down 100.0% sequentially.
Looking at the longer-term picture, PSNL's historical revenue data shows various trends over time. The company achieved its highest annual revenue of $85.5 million in 2021.
When compared to Healthcare sector peers including NTRA (+35.9% YoY), EXAS (+17.7% YoY), and GH (+39.6% YoY), PSNL has underperformed the peer group in terms of revenue growth. Compare PSNL vs NTRA →
PSNL Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| PSNLCurrent | $49M | -100.0% | - | - | |
 NTRA | $2.3B | +35.9% | +42.6% | -13.4% | |
 EXAS | $3.2B | +17.7% | +16.8% | -6.4% | |
 GH | $982M | +39.6% | +27.9% | -44.4% | |
 TWST | $377M | +17.8% | +33.1% | -36.2% | |
 ILMN | $4.3B | +1.2% | +6.0% | 19.9% |
PSNL Historical Revenue Data (2017–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $0 | -100.0% | $-53,871,000 | - | $-88,057,000 | - |
| 2024 | $84.6M | +15.2% | $26.8M | 31.7% | $-68,267,000 | -80.7% |
| 2023 | $73.5M | +13.0% | $18.2M | 24.8% | $-109,936,000 | -149.6% |
| 2022 | $65.0M | -23.9% | $13.3M | 20.5% | $-115,531,000 | -177.6% |
| 2021 | $85.5M | +8.7% | $31.7M | 37.0% | $-65,353,000 | -76.4% |
| 2020 | $78.6M | +20.6% | $20.1M | 25.6% | $-42,146,000 | -53.6% |
| 2019 | $65.2M | +72.6% | $22.1M | 33.9% | $-22,418,000 | -34.4% |
| 2018 | $37.8M | +302.2% | $11.8M | 31.3% | $-13,770,000 | -36.5% |
| 2017 | $9.4M | - | $-2,343,000 | -24.9% | $-22,163,000 | -236.0% |
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Start ComparisonPSNL — Frequently Asked Questions
Quick answers to the most common questions about buying PSNL stock.
Is PSNL's revenue growth accelerating or slowing?
PSNL revenue declined -100.0% year-over-year, contrasting with the 5-year CAGR of N/A. TTM revenue fell to $49M. This reverses the prior growth trend.
What is PSNL's long-term revenue growth rate?
Personalis, Inc.'s 5-year revenue CAGR of N/A reflects the variable expansion pattern. Current YoY growth of -100.0% is below this long-term average.
How is PSNL's revenue distributed by segment?
PSNL reports revenue by product line and geographic region. Annual and quarterly breakdowns from 2017-2025 are available for download. Segment mix reveals concentration and diversification trends.