Personalis, Inc. (PSNL) Revenue History
Annual and quarterly revenue from 2017 to present
PSNL Revenue Over Time (2017–2025)
PSNL Revenue Growth History
6 of 8 years with positive growth- FY2017 revenue growth
- N/A
- FY2018 revenue growth
- +302.2%
- FY2019 revenue growth
- +72.6%
- FY2020 revenue growth
- +20.6%
- FY2021 revenue growth
- +8.7%
- FY2022 revenue growth
- -23.9%
- FY2023 revenue growth
- +13.0%
- FY2024 revenue growth
- +15.2%
- FY2025 revenue growth
- -17.7%
| Quarter | Revenue | YoY |
|---|---|---|
| Q2 2026 | $22.4M | +30.0% |
| Q1 2026 | $15.5M | -24.9% |
| Q4 2025 | $17.3M | +3.2% |
| Q3 2025 | $14.5M | -43.6% |
| Q2 2025 | $17.2M | -23.8% |
| Q1 2025 | $20.6M | +5.5% |
| Q4 2024 | $16.8M | -14.6% |
| Q3 2024 | $25.7M | +40.9% |
Multi-year avg. share of annual revenue by fiscal quarter
PSNL Revenue Analysis (2017–2025)
Current Revenue & Growth
As of October 3, 2026, Personalis, Inc. (PSNL) generated trailing twelve-month (TTM) revenue of $69.7 million, reflecting exceptional growth of +30.0% year-over-year. The most recent quarter (Q2 2026) recorded $22.4 million in revenue, up 44.5% sequentially.
Historical Growth Trajectory
PSNL's 5-year compound annual growth rate (CAGR) stands at -2.4%, indicating revenue contraction over this period. The 3-year CAGR of +2.3% exceeds the 5-year average, indicating an acceleration in the most recent period. Personalis, Inc.'s highest annual revenue of $85.5 million was recorded in 2021.
Peer Comparison
Compared to Healthcare sector peers — including NTRA (+37.8% YoY), EXAS (+17.7% YoY), and GH (+42.7% YoY) — PSNL has outperformed the peer group in revenue growth. Compare PSNL vs NTRA →
PSNL Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| PSNLCurrent | $70M | +30.0% | -2.4% | -126.4% | |
 NTRA | $2.3B | +37.8% | +42.6% | -13.4% | |
 EXAS | $3.2B | +17.7% | +16.8% | -6.4% | |
 GH | $982M | +42.7% | +27.9% | -44.4% | |
 TWST | $377M | +19.2% | +33.1% | -36.2% | |
 ILMN | $4.3B | +4.9% | +6.0% | 19.9% |
PSNL Historical Revenue Data (2017–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $69.6M | -17.7% | $15.8M | 22.7% | $-88,057,000 | -126.4% |
| 2024 | $84.6M | +15.2% | $26.8M | 31.7% | $-68,267,000 | -80.7% |
| 2023 | $73.5M | +13.0% | $18.2M | 24.8% | $-96,294,000 | -131.0% |
| 2022 | $65.0M | -23.9% | $13.3M | 20.5% | $-115,531,000 | -177.6% |
| 2021 | $85.5M | +8.7% | $31.7M | 37.0% | $-65,353,000 | -76.4% |
| 2020 | $78.6M | +20.6% | $20.1M | 25.6% | $-42,146,000 | -53.6% |
| 2019 | $65.2M | +72.6% | $22.1M | 33.9% | $-22,418,000 | -34.4% |
| 2018 | $37.8M | +302.2% | $11.8M | 31.3% | $-13,770,000 | -36.5% |
| 2017 | $9.4M | - | $-2,343,000 | -24.9% | $-22,163,000 | -236.0% |
PSNL Chart Terminal
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Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
9+ years return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
PSNL — Frequently Asked Questions
Quick answers to the most common questions about buying PSNL stock.
Is PSNL's revenue growth accelerating or slowing?
PSNL revenue growth is accelerating. TTM revenue reached $70M, up +30.0% year-over-year — ahead of the 5-year CAGR of -2.4%. This indicates the business is expanding faster than its historical baseline.
What is PSNL's revenue history from 2017 to 2026?
Personalis, Inc. (PSNL) revenue history spans 2017 to 2026. TTM revenue as of 2026 is $70M, growing at +30.0% YoY. The 5-year CAGR is -2.4%. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is PSNL's long-term revenue growth rate (CAGR)?
Personalis, Inc.'s 5-year revenue CAGR of -2.4% reflects the sustained nature of its business expansion. As of 2026, the current YoY growth rate of +30.0% is above this long-term average. CAGR is the most reliable measure of sustained revenue momentum for PSNL.
Why does PSNL's quarterly revenue fluctuate?
PSNL quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. Personalis, Inc.'s revenue data from 2017 to 2026 shows full historical quarterly detail on this page.
How is PSNL's revenue distributed by segment?
PSNL reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does PSNL's revenue compare to industry peers?
Personalis, Inc. (PSNL) with TTM revenue of $70M and +30.0% YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.