8-K Announcements
6May 6, 2026·SEC
Mar 19, 2026·SEC
Nov 4, 2025·SEC
Taysha Gene Therapies, Inc. (TSHA) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Taysha Gene Therapies, Inc. (TSHA) stock price & volume — 10-year historical chart
Taysha Gene Therapies, Inc. (TSHA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Taysha Gene Therapies, Inc. (TSHA) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | May 6, 2026 | $0.12vs $0.10-20.0% | —vs $755,556 |
| Q2 2026 | Mar 19, 2026 | $0.08vs $0.11+27.3% | $5Mvs $2M+144.5% |
| Q4 2025 | Nov 4, 2025 | $0.09vs $0.09+0.0% | —vs $2M |
| Q3 2025 | Aug 12, 2025 | $0.09vs $0.07-28.6% | $2Mvs $2M+14.9% |
Taysha Gene Therapies, Inc. (TSHA) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison
Taysha Gene Therapies, Inc. (TSHA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Taysha Gene Therapies, Inc. (TSHA) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 2.5M | 15.45M | 8.33M | 9.77M | 7.47M |
| Revenue Growth % | - | - | - | - | 517.55% | -46.07% | 17.28% | 3.42% |
| Cost of Goods Sold | 0 | 9K | 0 | 2.49M | 0 | 0 | 1.15M | 585K |
| COGS % of Revenue | - | - | - | 99.4% | - | - | 11.72% | - |
| Gross Profit | 0▲ 0% | -9K▲ 0% | 0▲ 100.0% | 15K▲ 0% | 15.45M▲ 102913.5% | 8.33M▼ 46.1% | 8.63M▲ 3.5% | 6.89M▲ 0% |
| Gross Margin % | - | - | - | 0.6% | 100% | 100% | 88.28% | 92.17% |
| Gross Profit Growth % | - | - | 100% | - | 102913.53% | -46.07% | 3.54% | - |
| Operating Expenses | 1.11M | 42.99M | 173.27M | 126.04M | 87.89M | 99.79M | 119.13M | 139.45M |
| OpEx % of Revenue | - | - | - | 5037.65% | 568.83% | 1197.55% | 1218.93% | - |
| Selling, General & Admin | 128K | 11.1M | 41.32M | 34.87M | 30.05M | 28.95M | 32.72M | 35.39M |
| SG&A % of Revenue | - | - | - | 1393.81% | 194.47% | 347.45% | 334.83% | - |
| Research & Development | 987K | 31.89M | 131.94M | 91.17M | 56.78M | 66M | 86.4M | 104.06M |
| R&D % of Revenue | - | - | - | 3643.84% | 367.47% | 792.04% | 884.1% | - |
| Other Operating Expenses | 0 | 0 | 0 | 0 | 1.06M | 4.84M | 0 | 0 |
| Operating Income | -1.11M▲ 0% | -43M▼ 3756.7% | -173.27M▼ 302.9% | -126.03M▲ 27.3% | -72.44M▲ 42.5% | -91.46M▼ 26.3% | -110.5M▼ 20.8% | -132.56M▲ 0% |
| Operating Margin % | - | - | - | -5037.05% | -468.83% | -1097.55% | -1130.65% | -1774.37% |
| Operating Income Growth % | - | -3756.68% | -302.93% | 27.26% | 42.52% | -26.26% | -20.82% | - |
| EBITDA | 3.35M | -42.99M | -172.78M | -123.54M | -71.07M | -90.21M | -109.35M | -131.7M |
| EBITDA Margin % | - | - | - | -4937.65% | -459.96% | -1082.61% | -1118.93% | -1762.83% |
| EBITDA Growth % | - | -1385.29% | -301.87% | 28.5% | 42.47% | -26.94% | -21.22% | -50.78% |
| D&A (Non-Cash Add-back) | 4.46M | 9K | 492K | 2.49M | 1.37M | 1.25M | 1.15M | 862K |
| EBIT | -4.46M | -59.98M | -173.09M | -162.22M | -106.57M | -89.2M | -110.5M | -87.88M |
| Net Interest Income | 0 | 21K | -1.26M | -3.55M | -1.43M | 6.84M | 9.16M | 7.85M |
| Interest Income | 0 | 49K | 172K | 249K | 3.57M | 6.94M | 9.22M | 10.48M |
| Interest Expense | 0 | 28K | 1.43M | 3.8M | 5M | 102K | 63K | 35K |
| Other Income/Expense | 0 | -17.01M | -1.26M | -39.99M | -39.13M | 2.16M | 1.5M | 2.69M |
| Pretax Income | -1.11M▲ 0% | -60.01M▼ 5282.2% | -174.52M▼ 190.8% | -166.01M▲ 4.9% | -111.57M▲ 32.8% | -89.3M▲ 20.0% | -109M▼ 22.1% | -129.88M▲ 0% |
| Pretax Margin % | - | - | - | -6635.25% | -722.06% | -1071.62% | -1115.27% | -1738.4% |
| Income Tax | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
| Net Income | -1.11M▲ 0% | -43M▼ 3756.5% | -174.52M▼ 305.9% | -166.01M▲ 4.9% | -111.57M▲ 32.8% | -89.3M▲ 20.0% | -109M▼ 22.1% | -129.88M▲ 0% |
| Net Margin % | - | - | - | -6635.25% | -722.06% | -1071.62% | -1115.27% | -1738.4% |
| Net Income Growth % | - | -3756.5% | -305.87% | 4.88% | 32.8% | 19.96% | -22.06% | -49.69% |
| Net Income (Continuing) | -1.11M | -60.01M | -174.52M | -166.01M | -111.57M | -89.3M | -109M | -129.88M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.03▲ 0% | -3.40▼ 11195.7% | -4.64▼ 36.5% | -3.78▲ 18.5% | -0.96▲ 74.6% | -0.36▲ 62.5% | -0.34▲ 5.6% | -0.35▲ 0% |
| EPS Growth % | - | -11195.68% | -36.47% | 18.53% | 74.6% | 62.5% | 5.56% | -7.29% |
| EPS (Basic) | -0.03 | -3.40 | -4.64 | -3.78 | -0.96 | -0.36 | -0.34 | - |
| Diluted Shares Outstanding | 36.99M | 17.67M | 37.65M | 43.95M | 116.12M | 250.13M | 319.71M | 366.63M |
| Basic Shares Outstanding | 36.99M | 17.67M | 37.65M | 43.95M | 116.12M | 250.13M | 319.71M | 366.63M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - |
Taysha Gene Therapies, Inc. (TSHA) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 15K | 257.88M | 159.6M | 96.42M | 149.87M | 142.13M | 324.65M | 282.25M |
| Cash & Short-Term Investments | 0 | 251.25M | 149.1M | 87.88M | 143.94M | 139.04M | 319.77M | 276.58M |
| Cash Only | 0 | 251.25M | 149.1M | 87.88M | 143.94M | 139.04M | 319.77M | 276.58M |
| Short-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accounts Receivable | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Sales Outstanding | - | - | - | - | - | - | - | - |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - |
| Other Current Assets | 15K | 331K | 6.63M | 1.19M | 3.42M | 892K | 4.88M | 5.67M |
| Total Non-Current Assets | 15K | 1M | 54.35M | 29.86M | 22.86M | 18.23M | 18.67M | 18.1M |
| Property, Plant & Equipment | 0 | 287K | 50.61M | 25.91M | 20.41M | 15.87M | 16.18M | 15.61M |
| Fixed Asset Turnover | - | - | - | 0.10x | 0.76x | 0.53x | 0.60x | 0.49x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 0 | 2.64M | 0 | 0 | 0 | 2.31M | 2.31M |
| Other Non-Current Assets | 15K | 715K | 1.11M | 3.95M | 2.46M | 2.37M | 183K | 7.35M |
| Total Assets | 15K▲ 0% | 258.88M▲ 1725773.3% | 213.96M▼ 17.4% | 126.28M▼ 41.0% | 172.73M▲ 36.8% | 160.36M▼ 7.2% | 343.32M▲ 114.1% | 300.35M▲ 0% |
| Asset Turnover | - | - | - | 0.02x | 0.09x | 0.05x | 0.03x | 0.02x |
| Asset Growth % | - | 1725773.33% | -17.35% | -40.98% | 36.79% | -7.16% | 114.09% | 373.15% |
| Total Current Liabilities | 150K | 7.13M | 51.75M | 62.79M | 36.76M | 26.23M | 26.55M | 20.1M |
| Accounts Payable | 0 | 1.99M | 21.76M | 10.95M | 6.37M | 3.59M | 6.28M | 4.56M |
| Days Payables Outstanding | - | 80.87K | - | 1.61K | - | - | 2K | 3.74K |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 0 | 0 | 0 | 33.56M | 18.11M | 9.77M | 0 | 5.49M |
| Other Current Liabilities | 21K | 1.86M | 4.13M | 4.63M | 4.99M | 6.43M | 10.85M | 15.53M |
| Current Ratio | 0.10x | 36.17x | 3.08x | 1.54x | 4.08x | 5.42x | 12.23x | 12.23x |
| Quick Ratio | 0.10x | 36.17x | 3.08x | 1.54x | 4.08x | 5.42x | 12.23x | 12.23x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 0 | 450K | 66.83M | 62.54M | 61.04M | 62.61M | 69.83M | 68.31M |
| Long-Term Debt | 0 | 0 | 37.19M | 37.97M | 40.51M | 43.94M | 18.17M | 17.77M |
| Capital Lease Obligations | 0 | 0 | 25.9M | 20.44M | 18.95M | 17.36M | 0 | 33.37M |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 0 | 450K | 3.73M | 4.13M | 1.58M | 1.31M | 51.66M | 105.12M |
| Total Liabilities | 150K | 7.58M | 118.57M | 125.33M | 97.79M | 88.84M | 96.38M | 88.41M |
| Total Debt | 0 | 0 | 63.09M | 59.93M | 61.11M | 63.18M | 18.17M | 17.77M |
| Net Debt | 0 | -251.25M | -86.01M | -27.95M | -82.83M | -75.86M | -301.6M | -258.81M |
| Debt / Equity | - | - | 0.66x | 63.15x | 0.82x | 0.88x | 0.07x | 0.07x |
| Debt / EBITDA | - | - | - | - | - | - | - | -0.13x |
| Net Debt / EBITDA | - | - | - | - | - | - | - | 1.97x |
| Interest Coverage | - | -2142.25x | -121.21x | -42.71x | -21.32x | -874.47x | -1753.94x | -2510.94x |
| Total Equity | -135K▲ 0% | 251.3M▲ 186249.6% | 95.38M▼ 62.0% | 949K▼ 99.0% | 74.94M▲ 7796.4% | 71.53M▼ 4.6% | 246.94M▲ 245.2% | 211.94M▲ 0% |
| Equity Growth % | - | 186249.63% | -62.04% | -99.01% | 7796.42% | -4.55% | 245.25% | 805.27% |
| Book Value per Share | -0.00 | 14.23 | 2.53 | 0.02 | 0.65 | 0.29 | 0.77 | 0.58 |
| Total Shareholders' Equity | -135K | 251.3M | 95.38M | 949K | 74.94M | 71.53M | 246.94M | 211.94M |
| Common Stock | 0 | 0 | 0 | 1K | 2K | 2K | 3K | 3K |
| Retained Earnings | -1.11M | -61.13M | -235.65M | -401.44M | -513.01M | -602.3M | -711.3M | -753.71M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | 0 | 0 | 0 | 0 | 0 | -4.03M | -192K | 985K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Taysha Gene Therapies, Inc. (TSHA) cash flow — operating, investing & free cash flow history
| Line item | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|
| Cash from Operations | 135K | -30.73M | -117.04M | -88.39M | -73.02M | -81.22M | -93.09M | -93.09M |
| Operating CF Margin % | - | - | - | -3532.77% | -472.58% | -974.74% | -952.52% | - |
| Operating CF Growth % | - | -22862.22% | -280.88% | 24.48% | 17.39% | -11.24% | -14.61% | -137.25% |
| Net Income | -1.11M | -60.01M | -174.52M | -166.01M | -111.57M | -89.3M | -109M | -129.88M |
| Depreciation & Amortization | 0 | 9K | 492K | 1.17M | 1.37M | 1.25M | 1.15M | 1.3M |
| Stock-Based Compensation | 0 | 3.35M | 18.18M | 18.04M | 7.91M | 13.1M | 13.3M | 15.55M |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 710K | 26.03M | 10.14M | 39.89M | 47.28M | 6.19M | 6.83M | -60K |
| Working Capital Changes | 540K | -111K | 28.67M | 18.52M | -18.01M | -12.47M | -5.37M | 1.13M |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 0 | 1.96M | 14.49M | -7.8M | -2.29M | -2.92M | -153K | 2.16M |
| Cash from Investing | 0 | -9.08M | -21.55M | -24.93M | -7.35M | -363K | -604K | -3.26M |
| Capital Expenditures | 0 | -82K | -21.55M | -24.87M | -3.87M | -374K | -738K | -384K |
| CapEx % of Revenue | - | - | - | 993.96% | 25.04% | 4.49% | 7.55% | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - |
| Other Investing | 0 | -9M | 0 | -61K | -3.48M | 11K | 134K | -2.87M |
| Cash from Financing | 0 | 291.06M | 39.08M | 52.1M | 136.39M | 76.68M | 274.59M | 275.35M |
| Debt Issued (Net) | 0 | 0 | 39.96M | 0 | -3.45M | 0 | 9.24M | 0 |
| Equity Issued (Net) | 0 | 291.06M | -360K | 53.24M | 140.79M | 76.78M | 265.69M | 265.61M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -173K |
| Other Financing | 0 | 0 | -514K | -1.15M | -947K | -96K | -337K | 9.74M |
| Net Change in Cash | 135K▲ 0% | 251.25M▲ 186013.3% | -99.51M▼ 139.6% | -61.22M▲ 38.5% | 56.02M▲ 191.5% | -4.9M▼ 108.8% | 180.9M▲ 3788.7% | 160.15M▲ 0% |
| Free Cash Flow | 135K▲ 0% | -39.81M▼ 29589.6% | -138.6M▼ 248.1% | -113.26M▲ 18.3% | -80.39M▲ 29.0% | -81.6M▼ 1.5% | -93.83M▼ 15.0% | -112.33M▲ 0% |
| FCF Margin % | - | - | - | -4526.74% | -520.27% | -979.23% | -960.07% | -1503.57% |
| FCF Growth % | - | -29589.63% | -248.13% | 18.28% | 29.02% | -1.51% | -14.99% | -33.63% |
| FCF per Share | 0.00 | -2.25 | -3.68 | -2.58 | -0.69 | -0.33 | -0.29 | -0.29 |
| FCF Conversion (FCF/Net Income) | -0.12x | 0.71x | 0.67x | 0.53x | 0.65x | 0.91x | 0.85x | 0.86x |
| Interest Paid | 0 | 28K | 641K | 2.77M | 4.95M | 5.28M | 0 | 1.36M |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Taysha Gene Therapies, Inc. (TSHA) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | TTM |
|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -34.24% | -100.68% | -344.67% | -294.04% | -121.94% | -68.45% | -56.07% |
| Return on Invested Capital (ROIC) | - | -2758.74% | - | - | - | - | 345.12% |
| Gross Margin | - | - | 0.6% | 100% | 100% | 88.28% | 92.17% |
| Net Margin | - | - | -6635.25% | -722.06% | -1071.62% | -1115.27% | -1738.4% |
| Debt / Equity | - | 0.66x | 63.15x | 0.82x | 0.88x | 0.07x | 0.07x |
| Interest Coverage | -2142.25x | -121.21x | -42.71x | -21.32x | -874.47x | -1753.94x | -2510.94x |
| FCF Conversion | 0.71x | 0.67x | 0.53x | 0.65x | 0.91x | 0.85x | 0.86x |
| Revenue Growth | - | - | - | 517.55% | -46.07% | 17.28% | 3.42% |
Taysha Gene Therapies, Inc. (TSHA) SEC filings — annual & quarterly reports (10-K, 10-Q)
May 6, 2026·SEC
Mar 19, 2026·SEC
Nov 4, 2025·SEC
Taysha Gene Therapies, Inc. (TSHA) stock FAQ — growth, dividends, profitability & financials explained
Taysha Gene Therapies, Inc. (TSHA) reported $7.5M in revenue for fiscal year 2025.
Taysha Gene Therapies, Inc. (TSHA) grew revenue by 17.3% over the past year. This is strong growth.
Taysha Gene Therapies, Inc. (TSHA) reported a net loss of $129.9M for fiscal year 2025.
Taysha Gene Therapies, Inc. (TSHA) has a return on equity (ROE) of -68.5%. Negative ROE indicates the company is unprofitable.
Taysha Gene Therapies, Inc. (TSHA) had negative free cash flow of $112.3M in fiscal year 2025, likely due to heavy capital investments.
Taysha Gene Therapies, Inc. (TSHA) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates