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XFOR logoX4 Pharmaceuticals, Inc.(XFOR)Earnings, Financials & Key Ratios

XFOR•NASDAQ
Price updated Jun 11, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutX4 Pharmaceuticals, Inc., a late-stage clinical biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is mavorixafor, a small molecule inhibitor of the chemokine receptor C-X-C chemokine receptor type 4 (CXCR4), which is in Phase III clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome; and Phase Ib clinical trial to treat chronic neutropenia and Waldenström macroglobulinemia. The company is also developing X4P-002, a CXCR4 antagonist for the treatment of brain cancers; and X4P-003, a CXCR4 antagonist for the treatment of CXCR4 disorders and primary immunodeficiencies. It has a license agreement with Abbisko Therapeutics Co., Ltd. to develop, manufacture, and commercialize mavorixafor in combination with checkpoint inhibitors or other agents in oncology indications. The company was founded in 2010 and is headquartered in Boston, Massachusetts.Show more
  • Revenue$35M+1273.2%
  • EBITDA-$86M-140.4%
  • Net Income-$79M-111.5%
  • EPS (Diluted)-1.87+66.5%
  • Gross Margin82.18%+19.4%
  • EBITDA Margin-243.8%+82.5%
  • Operating Margin-247.44%+82.6%
  • Net Margin-225.55%+84.6%
  • ROE-75.99%+25.7%
  • ROIC-143.12%-43.4%
  • Debt/Equity0.41-88.2%
  • Interest Coverage-9.79-202.5%

XFOR Key Insights

X4 Pharmaceuticals, Inc. (XFOR) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 63.6%
  • ✓Trading at only 0.9x book value

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 100.0% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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XFOR Price & Volume

X4 Pharmaceuticals, Inc. (XFOR) stock price & volume — 10-year historical chart

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XFOR Growth Metrics

X4 Pharmaceuticals, Inc. (XFOR) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years63.56%
3 Years-
TTM-71.26%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-783.12%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-313.15%

Return on Capital

10 Years-66.74%
5 Years-60.89%
3 Years-53.33%
Last Year-45.94%

XFOR Recent Earnings

X4 Pharmaceuticals, Inc. (XFOR) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 7/12 qtrs (58%)●Beat Revenue 4/12 qtrs (50%)
Q2 2026Latest
May 6, 2026
EPS
$0.16
Est $0.20
+20.0%
Revenue
$2M
Est $3M
-22.8%
Q2 2026
Mar 17, 2026
EPS
$0.22
Est $0.36
+38.9%
Revenue
$3M
Est $2M
+48.2%
Q4 2025
Nov 5, 2025
EPS
$0.69
Est $0.79
+12.7%
Revenue
$2M
Est $2M
+1.8%
Q3 2025
Aug 8, 2025
EPS
$3.47
Est $4.53
+23.4%
Revenue
$2M
Est $2M
-11.4%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 6, 2026
$0.16vs $0.20+20.0%
$2Mvs $3M-22.8%
Q2 2026Mar 17, 2026
$0.22vs $0.36+38.9%
$3Mvs $2M+48.2%
Q4 2025Nov 5, 2025
$0.69vs $0.79+12.7%
$2Mvs $2M+1.8%
Q3 2025Aug 8, 2025
$3.47vs $4.53+23.4%
$2Mvs $2M-11.4%
Based on last 12 quarters of dataView full earnings history →

XFOR Peer Comparison

X4 Pharmaceuticals, Inc. (XFOR) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
CYCN logoCYCNCyclerion Therapeutics, Inc.Direct Competitor13.9M3.21-2.953.7%-264.73%-62.1%
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor7.16B247.98-18.40-100%-43.02%0.00
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor6.77B82.96-22.48-16.72%-6.12%-25.02%0.05
IMVT logoIMVTImmunovant, Inc.Direct Competitor6.75B32.88-11.87-68.16%0.00
ARDX logoARDXArdelyx, Inc.Direct Competitor1.42B5.79-22.2722.09%-13.58%-38.11%1.27
AGEN logoAGENAgenus Inc.Direct Competitor141.17M3.39-997.0610.37%52.16%
RARE logoRAREUltragenyx Pharmaceutical Inc.Product Competitor2.36B23.98-4.1120.13%-91.03%-6.08%
FOLD logoFOLDAmicus Therapeutics, Inc.Product Competitor4.55B14.49-164.8520.05%-4.27%-12.02%1.76

Compare XFOR vs Peers

X4 Pharmaceuticals, Inc. (XFOR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CYCN

Most directly comparable listed peer for XFOR.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare XFOR against a more recognizable public peer.

Peer Set

Compare Top 5

vs CYCN, PRAX, KYMR, IMVT

XFOR Income Statement

X4 Pharmaceuticals, Inc. (XFOR) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0003M0002.56M35.11M9.01M
Revenue Growth %
-----100%---1273.21%-71.26%
Cost of Goods Sold
195K103K672K1.23M1.89M00797K6.26M1.85M
COGS % of Revenue
---41%---31.17%17.82%-
Gross Profit
-195K▲ 0%
-103K▲ 47.2%
-672K▼ 552.4%
1.77M▲ 363.4%
-1.89M▼ 206.9%
0▲ 100.0%
0▲ 0%
1.76M▲ 0%
28.86M▲ 1539.5%
7.16M▲ 0%
Gross Margin %
---59%---68.83%82.18%79.44%
Gross Profit Growth %
35%47.18%-552.43%363.39%-206.89%100%--1539.55%-
Operating Expenses
35.94M28.98M46.13M61.64M73.46M87.57M107.52M38.16M115.74M104.91M
OpEx % of Revenue
---2054.8%---1492.41%329.62%-
Selling, General & Admin
7.81M8.64M15.97M20.94M24.7M27.02M35.51M61.52M43.52M35.46M
SG&A % of Revenue
---698.07%---2405.87%123.93%-
Research & Development
28.13M20.35M30.16M40.7M48.76M61.06M72.02M81.64M72.22M69.45M
R&D % of Revenue
---1356.73%---3192.92%205.69%-
Other Operating Expenses
00000-509K0-105M00
Operating Income
-36.13M▲ 0%
-29.09M▲ 19.5%
-46.8M▼ 60.9%
-59.87M▼ 27.9%
-75.35M▼ 25.8%
-87.57M▼ 16.2%
-107.52M▼ 22.8%
-36.4M▲ 66.1%
-86.88M▼ 138.7%
-97.75M▲ 0%
Operating Margin %
----1995.8%----1423.58%-247.44%-1084.38%
Operating Income Growth %
-48.41%19.51%-60.92%-27.93%-25.85%-16.22%-22.79%66.15%-138.68%-
EBITDA
-35.94M-28.98M-46.13M-58.64M-73.46M-87.06M-107.1M-35.6M-85.61M-96.7M
EBITDA Margin %
----1954.8%----1392.45%-243.8%-1072.73%
EBITDA Growth %
-49.46%19.36%-59.17%-27.12%-25.26%-18.51%-23.03%66.76%-140.43%13.91%
D&A (Non-Cash Add-back)
195K103K672K1.23M1.89M513K419K796K1.28M1.05M
EBIT
-36.13M-29.09M-46.8M-59.87M-75.35M-89.85M-95.31M-28.37M-86.88M-97.75M
Net Interest Income
-1.86M-484K-950K-2.42M-3.63M-3.77M-1.2M-3M-4.3M-3.15M
Interest Income
214K236K1.2M273K10K219K4.58M5.77M4.58M5.66M
Interest Expense
2.08M720K2.15M2.69M3.64M3.99M5.78M8.77M8.88M8.81M
Other Income/Expense
2.26M-4.2M-6M-2.11M-13.33M-6.27M6.43M-739K7.72M-1.97M
Pretax Income
-33.88M▲ 0%
-33.28M▲ 1.7%
-52.81M▼ 58.7%
-61.98M▼ 17.4%
-88.68M▼ 43.1%
-93.84M▼ 5.8%
-101.09M▼ 7.7%
-37.14M▲ 63.3%
-79.16M▼ 113.1%
-99.72M▲ 0%
Pretax Margin %
----2066.1%----1452.48%-225.44%-1106.22%
Income Tax
000148K17K28K78K310K41K7K
Effective Tax Rate %
0%0%0%-0.24%-0.02%-0.03%-0.08%-0.83%-0.05%-0.01%
Net Income
-33.88M▲ 0%
-33.28M▲ 1.7%
-52.81M▼ 58.7%
-62.13M▼ 17.7%
-88.7M▼ 42.8%
-93.87M▼ 5.8%
-101.17M▼ 7.8%
-37.45M▲ 63.0%
-79.2M▼ 111.5%
-99.72M▲ 0%
Net Margin %
----2071.03%----1464.61%-225.55%-1106.3%
Net Income Growth %
-47.45%1.75%-58.65%-17.66%-42.76%-5.83%-7.78%62.98%-111.48%-783.12%
Net Income (Continuing)
-33.88M-33.28M-52.81M-62.13M-88.7M-93.87M-101.17M-37.45M-79.2M-99.72M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-17767.00▲ 0%
-14238.00▲ 19.9%
-138.94▲ 99.0%
-92.84▲ 33.2%
-119.58▼ 28.8%
-45.60▲ 61.9%
-17.07▲ 62.6%
-5.59▲ 67.3%
-1.87▲ 66.5%
-0.79▲ 0%
EPS Growth %
-922.42%19.86%99.02%33.18%-28.8%61.87%62.57%67.25%66.55%-313.15%
EPS (Basic)
-17767.00-14238.00-138.94-92.84-119.58-45.60-17.07-5.59-1.87-
Diluted Shares Outstanding
1.91K2.55K384.33K669.23K858.3K2.12M5.93M6.7M42.29M126.29M
Basic Shares Outstanding
1.91K2.55K384.33K669.23K858.3K2.12M5.93M6.7M42.29M126.29M
Dividend Payout Ratio
----------

XFOR Balance Sheet

X4 Pharmaceuticals, Inc. (XFOR) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
79.53M9.34M129.28M83.31M87.88M128.68M122.08M112.17M261.58M241.98M
Cash & Short-Term Investments
76.79M8.13M126.18M78.97M81.79M121.72M114.22M102.06M253M233.72M
Cash Only
76.79M8.13M126.18M78.97M81.79M121.72M99.22M55.7M217.05M216.91M
Short-Term Investments
00000015M46.36M35.95M16.81M
Accounts Receivable
1.61M02M917K747K1.15M562K1.71M573K1.11M
Days Sales Outstanding
---111.57---244.095.9652.21
Inventory
00000002.82M4.48M4.64M
Days Inventory Outstanding
-------1.29K261.28805.93
Other Current Assets
348K198K1.1M3.42M5.34M5.81M7.3M5.59M3.53M2.51M
Total Non-Current Assets
1.72M605K31.42M39.56M29.3M26.91M25.18M34.27M28.88M28.3M
Property, Plant & Equipment
421K241K2.36M9.2M10.22M8.33M6.39M4.84M1.59M1.18M
Fixed Asset Turnover
---0.33x---0.53x22.07x4.70x
Goodwill
0027.11M27.11M17.35M17.35M17.35M17.35M17.35M17.35M
Intangible Assets
000000010M9.25M9.06M
Long-Term Investments
355K364K1.9M1.73M1.32M00000
Other Non-Current Assets
948K047K1.53M402K1.23M1.44M2.08M692K704K
Total Assets
81.25M▲ 0%
9.94M▼ 87.8%
160.7M▲ 1516.0%
122.87M▼ 23.5%
117.18M▼ 4.6%
155.59M▲ 32.8%
147.26M▼ 5.4%
146.45M▼ 0.6%
290.46M▲ 98.3%
270.28M▲ 0%
Asset Turnover
---0.02x---0.02x0.12x0.04x
Asset Growth %
968.57%-87.76%1516.03%-23.54%-4.63%32.78%-5.35%-0.55%98.34%147.96%
Total Current Liabilities
10.68M7.91M9.45M11.95M14.02M22.32M22.86M32.88M25.76M23.77M
Accounts Payable
1.89M2.97M2.09M3.14M4.28M7.78M8.95M8.62M5.7M5.07M
Days Payables Outstanding
3.54K10.52K1.13K932.98826.27--3.95K332.271.16K
Short-Term Debt
2.31M1.69M898K786K1.87M1.31M000733K
Deferred Revenue (Current)
694K737K000000464K2.72M
Other Current Liabilities
3.33M1.59M3.54M4.26M2.45M6.59M8.2M13.05M4.3M17.05M
Current Ratio
7.45x1.18x13.68x6.97x6.27x5.76x5.34x3.41x10.16x10.18x
Quick Ratio
7.45x1.18x13.68x6.97x6.27x5.76x5.34x3.33x9.98x9.98x
Cash Conversion Cycle
--------2.41K-65.04-300.63
Total Non-Current Liabilities
11.87M13.71M22.03M38.12M38.74M59.21M73.3M91.42M78.41M78.06M
Long-Term Debt
9.92M8.14M20.1M33.18M33.14M32.3M54.57M75.42M76.29M0
Capital Lease Obligations
001.92M4.48M4.78M3.6M2.61M1.41M0910K
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
9K5.15M16K462K826K23.3M16.11M14.59M1.5M78.06M
Total Liabilities
22.55M21.62M31.48M50.07M52.76M81.53M96.16M124.3M104.17M101.83M
Total Debt
12.24M9.83M22.91M38.45M39.78M38.42M58.28M78.09M77.28M733K
Net Debt
-64.56M1.7M-103.27M-40.52M-42M-83.3M-40.94M22.39M-139.76M-216.18M
Debt / Equity
0.21x-0.18x0.53x0.62x0.52x1.14x3.53x0.41x0.00x
Debt / EBITDA
----------0.01x
Net Debt / EBITDA
---------2.24x
Interest Coverage
-17.38x-40.40x-21.80x-22.27x-20.69x-22.50x-16.50x-3.24x-9.79x-11.10x
Total Equity
58.71M▲ 0%
-11.68M▼ 119.9%
129.22M▲ 1206.6%
72.8M▼ 43.7%
64.41M▼ 11.5%
74.05M▲ 15.0%
51.1M▼ 31.0%
22.15M▼ 56.7%
186.29M▲ 741.1%
168.45M▲ 0%
Equity Growth %
451.03%-119.89%1206.62%-43.66%-11.52%14.96%-30.99%-56.65%741.08%1282.81%
Book Value per Share
30752.75-4581.01336.22108.7875.0534.978.623.304.401.33
Total Shareholders' Equity
58.71M-11.68M129.22M72.8M64.41M74.05M51.1M22.15M186.29M168.45M
Common Stock
15K016K16K28K122K167K6K91K94K
Retained Earnings
-92.27M-79.24M-132.04M-194.18M-282.87M-376.74M-477.9M-515.36M-594.55M-614.79M
Treasury Stock
0000000000
Accumulated OCI
127K0-119K-119K-119K-119K-119K-122K-109K-122K
Minority Interest
0000000000

XFOR Cash Flow Statement

X4 Pharmaceuticals, Inc. (XFOR) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-27.87M-25.42M-48.05M-58.82M-70.91M-77.1M-96.51M-130.9M-85.62M-92.85M
Operating CF Margin %
----1960.6%----5119.32%-243.84%-
Operating CF Growth %
-28.8%8.79%-89.04%-22.4%-20.55%-8.74%-25.17%-35.63%34.59%13.97%
Net Income
-33.88M-33.28M-52.81M-62.13M-88.7M-93.87M-101.17M-37.45M-79.2M-99.72M
Depreciation & Amortization
195K103K672K1.23M1.89M513K419K796K1.28M1.04M
Stock-Based Compensation
000005.2M8.69M8.2M4.3M3.78M
Deferred Taxes
0000000000
Other Non-Cash Items
2.39M4.63M7.32M6.15M17.4M5.32M-4.79M-105.13M-9.42M3.77M
Working Capital Changes
3.42M3.13M-3.24M-4.06M-1.5M5.74M344K2.67M-2.58M-1.71M
Change in Receivables
-64K-1.37M00000-1.07M497K-605K
Change in Inventory
0000000-2.82M-1.66M-1.55M
Change in Payables
182K1.31M-2.75M1.03M1.17M3.42M1.23M-286K-2.98M-6.08M
Cash from Investing
-42K027.23M-1.36M-615K-103K-14.88M66.99M8.15M30.54M
Capital Expenditures
-42K0-174K-1.36M-615K-103K-60K-326K-3M0
CapEx % of Revenue
---45.4%---12.75%8.54%0%
Acquisitions
0026.41M0000000
Investments
----------
Other Investing
001M000098M00
Cash from Financing
101.26M6.87M140.66M12.39M74.25M117.23M88.52M20.29M238.63M238.63M
Debt Issued (Net)
3.28M-1.14M481K12.39M0-795K20.44M20M00
Equity Issued (Net)
105.86M3.34M140.18M284K74.25M122.63M60M0238.53M238.58M
Dividends Paid
0000000000
Share Repurchases
-197K-1.13M00-2M00000
Other Financing
-7.87M4.67M0-278K0-4.61M8.08M294K98K54K
Net Change in Cash
73.76M▲ 0%
-68.66M▼ 193.1%
118.05M▲ 271.9%
-47.21M▼ 140.0%
2.81M▲ 106.0%
39.92M▲ 1318.1%
-22.78M▼ 157.1%
-43.77M▼ 92.2%
161.38M▲ 468.7%
175.85M▲ 0%
Free Cash Flow
-27.91M▲ 0%
-25.42M▲ 8.9%
-48.23M▼ 89.7%
-60.18M▼ 24.8%
-71.52M▼ 18.8%
-77.2M▼ 7.9%
-96.57M▼ 25.1%
-138.23M▼ 43.1%
-88.62M▲ 35.9%
-73.25M▲ 0%
FCF Margin %
----2006%----5405.83%-252.38%-812.62%
FCF Growth %
-28.56%8.93%-89.73%-24.78%-18.84%-7.95%-25.09%-43.13%35.89%33.37%
FCF per Share
-14621.79-9972.54-125.49-89.92-83.33-36.46-16.29-20.62-2.10-0.58
FCF Conversion (FCF/Net Income)
0.82x0.76x0.91x0.95x0.80x0.82x0.95x3.50x1.08x0.73x
Interest Paid
000003.01M4.6M7.77M8.05M0
Taxes Paid
0000000000

XFOR Key Ratios

X4 Pharmaceuticals, Inc. (XFOR) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)-161.38%-141.55%-89.85%-61.51%-129.28%-135.58%-161.67%-102.26%-75.99%-94.9%
Return on Invested Capital (ROIC)---439.6%-154.25%-206.68%-997.9%-17588.11%-99.82%-143.12%-264.37%
Gross Margin---59%---68.83%82.18%79.44%
Net Margin----2071.03%----1464.61%-225.55%-1106.3%
Debt / Equity0.21x-0.18x0.53x0.62x0.52x1.14x3.53x0.41x0.00x
Interest Coverage-17.38x-40.40x-21.80x-22.27x-20.69x-22.50x-16.50x-3.24x-9.79x-11.10x
FCF Conversion0.82x0.76x0.91x0.95x0.80x0.82x0.95x3.50x1.08x0.73x
Revenue Growth-----100%---1273.21%-71.26%
Related:XFOR Dividend History·XFOR Revenue History·XFOR Price History·XFOR P/E History·XFOR Financial Ratios·XFOR Institutional Holders

XFOR SEC Filings & Documents

X4 Pharmaceuticals, Inc. (XFOR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 12, 2026·SEC

Material company update

Nov 5, 2025·SEC

Material company update

Oct 27, 2025·SEC

10-K Annual Reports

3
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 26, 2025·SEC

FY 2024

Mar 21, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 6, 2026·SEC

FY 2025

Nov 5, 2025·SEC

FY 2025

Aug 8, 2025·SEC

XFOR Frequently Asked Questions

X4 Pharmaceuticals, Inc. (XFOR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

X4 Pharmaceuticals, Inc. (XFOR) reported $9.0M in revenue for fiscal year 2025.

X4 Pharmaceuticals, Inc. (XFOR) grew revenue by 1273.2% over the past year. This is strong growth.

X4 Pharmaceuticals, Inc. (XFOR) reported a net loss of $99.7M for fiscal year 2025.

Dividend & Returns

X4 Pharmaceuticals, Inc. (XFOR) has a return on equity (ROE) of -76.0%. Negative ROE indicates the company is unprofitable.

X4 Pharmaceuticals, Inc. (XFOR) had negative free cash flow of $73.3M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in XFOR back in 2015?

Total return calculator · dividends reinvested · 11+ years of data

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How much would $100/month in XFOR be worth today?

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