| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| ALNYAlnylam Pharmaceuticals, Inc. | 44.07B | 332.92 | 142.88 | 65.19% | 8.45% | 39.76% | 1.06% | 3.76 |
| SLXNWSilexion Therapeutics Ltd. | 63.6M | 0.03 | 0.00 | -132.54% | ||||
| EDITEditas Medicine, Inc. | 205.18M | 2.20 | -0.76 | -58.64% | -430.84% | -14.85% | 0.26 | |
| SGMOSangamo Therapeutics, Inc. | 92.01M | 0.43 | -0.88 | -67.2% | -331.28% | -17.44% | 1.34 | |
| CAMPCAMP4 Therapeutics Corporation | 210.49M | 4.49 | -1.69 | 86.29% | -14.04% | -133.54% | 0.14 | |
| SLNSilence Therapeutics plc | 256.95M | 5.44 | -1.71 | 70.47% | -252.16% | -84.61% | 0.00 | |
| PEPGPepGen Inc. | 202.89M | 6.22 | -2.18 | -57.35% | 0.16 | |||
| ARCTArcturus Therapeutics Holdings Inc. | 224.14M | 8.23 | -2.74 | -12.27% | -72.48% | -29.71% | 0.12 |
Analyze head-to-head performance against top industry competitors across valuation, growth, and profitability metrics.
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 372.78M | 514.18M | 599.67M | 1.12B | 729.26M | 810.46M | 587.37M | 787.65M | 705.14M | 944M |
| Revenue Growth % | 31.4% | 37.93% | 16.63% | 87.2% | -35.04% | 11.13% | -27.53% | 34.1% | -10.48% | 33.87% |
| Cost of Goods Sold | 0 | 0 | 1.82M | 4.38M | 11.95M | 10.84M | 14.12M | 9.13M | 11.21M | 16M |
| COGS % of Revenue | - | - | 0.3% | 0.39% | 1.64% | 1.34% | 2.4% | 1.16% | 1.59% | 1.69% |
| Gross Profit | 372.78M | 514.18M | 597.85M | 1.12B | 717.32M | 799.61M | 573.25M | 778.51M | 693.92M | 928M |
| Gross Margin % | 100% | 100% | 99.7% | 99.61% | 98.36% | 98.66% | 97.6% | 98.84% | 98.41% | 98.31% |
| Gross Profit Growth % | 1066.02% | 37.93% | 16.27% | 87.04% | -35.85% | 11.47% | -28.31% | 35.81% | -10.87% | 33.73% |
| Operating Expenses | 392.94M | 483.13M | 659.23M | 752.33M | 889.4M | 829.8M | 983.44M | 1.13B | 1.17B | 1.31B |
| OpEx % of Revenue | 105.41% | 93.96% | 109.93% | 67.02% | 121.96% | 102.39% | 167.43% | 143.75% | 165.78% | 138.77% |
| Selling, General & Admin | 48.62M | 108.49M | 244.62M | 286.64M | 332.2M | 170.9M | 150.29M | 232.6M | 267.5M | 394M |
| SG&A % of Revenue | 13.04% | 21.1% | 40.79% | 25.53% | 45.55% | 21.09% | 25.59% | 29.53% | 37.94% | 41.74% |
| Research & Development | 344.32M | 374.64M | 414.6M | 466M | 535M | 643M | 833M | 899.63M | 901.53M | 916M |
| R&D % of Revenue | 92.37% | 72.86% | 69.14% | 41.51% | 73.36% | 79.34% | 141.82% | 114.22% | 127.85% | 97.03% |
| Other Operating Expenses | 0 | 0 | 0 | -312K | 22.2M | 15.9M | 147K | 19K | -26K | 0 |
| Operating Income | -20.16M | 31.05M | -61.37M | 365.88M | -172.08M | -30.19M | -410.19M | -353.73M | -475.08M | -382M |
| Operating Margin % | -5.41% | 6.04% | -10.23% | 32.59% | -23.6% | -3.72% | -69.84% | -44.91% | -67.37% | -40.47% |
| Operating Income Growth % | 73.39% | 254% | -297.67% | 696.17% | -147.03% | 82.46% | -1258.88% | 13.76% | -34.31% | 19.59% |
| EBITDA | -11.13M | 39.4M | -48.84M | 381.88M | -154.92M | -10.63M | -388.09M | -331.23M | -453.09M | -382M |
| EBITDA Margin % | -2.98% | 7.66% | -8.15% | 34.02% | -21.24% | -1.31% | -66.07% | -42.05% | -64.26% | -40.47% |
| EBITDA Growth % | 83.02% | 454.06% | -223.98% | 881.83% | -140.57% | 93.14% | -3552.23% | 14.65% | -36.79% | 15.69% |
| D&A (Non-Cash Add-back) | 9.03M | 8.35M | 12.53M | 15.99M | 17.16M | 19.56M | 22.11M | 22.5M | 21.99M | 0 |
| EBIT | -18.67M | 27.99M | -31.37M | 351.21M | -128.35M | -24.75M | -249.86M | -258.37M | -375.71M | -382M |
| Net Interest Income | -33.38M | -36.57M | -14.6M | 3.44M | 21.05M | 695K | 17.21M | 7.58M | 16.57M | -73M |
| Interest Income | 5.42M | 8.18M | 30.19M | 52.2M | 30.56M | 10.04M | 25.33M | 89.04M | 107.02M | 0 |
| Interest Expense | 38.8M | 44.75M | 44.79M | 48.77M | 9.51M | 9.35M | 8.12M | 81.46M | 90.45M | 73M |
| Other Income/Expense | -37.31M | -47.81M | -14.78M | -27.12M | 37.53M | 1.04M | 152.21M | 19.77M | 15.01M | 2M |
| Pretax Income | -57.47M | -16.76M | -76.16M | 338.77M | -134.55M | -29.15M | -257.99M | -333.96M | -460.07M | -380M |
| Pretax Margin % | -15.42% | -3.26% | -12.7% | 30.18% | -18.45% | -3.6% | -43.92% | -42.4% | -65.25% | -40.25% |
| Income Tax | 2.93M | -5.98M | -291.14M | 51.51M | 345.19M | -551K | 11.74M | 32.32M | -6.17M | 1M |
| Effective Tax Rate % | 105.11% | -2.06% | -359.45% | 82.1% | 330.18% | 98.11% | 104.55% | 109.68% | 98.66% | 100.26% |
| Net Income | -60.4M | 346K | 273.74M | 278.14M | -444.26M | -28.6M | -269.72M | -366.29M | -453.9M | -381M |
| Net Margin % | -16.2% | 0.07% | 45.65% | 24.78% | -60.92% | -3.53% | -45.92% | -46.5% | -64.37% | -40.36% |
| Net Income Growth % | 31.58% | 100.57% | 79015.9% | 1.61% | -259.72% | 93.56% | -843.18% | -35.8% | -23.92% | 16.06% |
| Net Income (Continuing) | -60.4M | -10.78M | 214.99M | 287.26M | -479.74M | -28.6M | -269.72M | -366.29M | -453.9M | -381M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 84.27M | 139.08M | 213.45M | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.72 | -0.05 | 2.04 | 2.06 | -3.18 | -0.20 | -1.90 | -2.56 | -3.04 | -2.38 |
| EPS Growth % | 2.7% | 93.43% | 4412.9% | 0.98% | -254.37% | 93.71% | -850% | -34.74% | -18.75% | 21.71% |
| EPS (Basic) | -0.72 | -0.05 | 2.07 | 2.10 | -3.18 | -0.20 | -1.90 | -2.56 | -3.04 | -2.38 |
| Diluted Shares Outstanding | 120.93M | 126.1M | 134.06M | 142.87M | 139.61M | 141.02M | 141.85M | 143.19M | 149.51M | 160M |
| Basic Shares Outstanding | 120.8M | 124.02M | 132.32M | 140M | 139.61M | 141.02M | 141.85M | 143M | 149.51M | 160M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 797.93M | 1.17B | 2.21B | 2.72B | 2.13B | 2.35B | 2.2B | 2.64B | 2.62B | 2.99B |
| Cash & Short-Term Investments | 665.22M | 1.02B | 2.08B | 2.5B | 1.89B | 2.13B | 2B | 2.33B | 2.3B | 2.68B |
| Cash Only | 84.69M | 129.63M | 278.82M | 683.29M | 397.66M | 869.19M | 276.47M | 399.27M | 242.08M | 372.26M |
| Short-Term Investments | 2.41M | 893.09M | 1.81B | 1.82B | 1.49B | 1.26B | 1.72B | 1.93B | 2.06B | 2.31B |
| Accounts Receivable | 108.04M | 62.95M | 12.76M | 63.03M | 76.2M | 61.9M | 25.54M | 97.78M | 92.19M | 66M |
| Days Sales Outstanding | 105.79 | 44.69 | 7.77 | 20.49 | 38.14 | 27.88 | 15.87 | 45.31 | 47.72 | 25.52 |
| Inventory | 7.49M | 9.98M | 8.58M | 18.18M | 21.96M | 24.81M | 22.03M | 7.44M | 12.51M | 0 |
| Days Inventory Outstanding | - | - | 1.72K | 1.51K | 671.07 | 835.1 | 569.71 | 297.38 | 407.21 | - |
| Other Current Assets | 17.18M | 73.08M | 102.47M | 139.84M | 140.16M | 125.17M | 157.72M | 205.43M | 217.93M | 247M |
| Total Non-Current Assets | 114.53M | 154.04M | 459.9M | 512.51M | 259.05M | 266.64M | 331.18M | 348.22M | 383.38M | 534M |
| Property, Plant & Equipment | 92.84M | 121.91M | 132.16M | 153.65M | 181.08M | 196.04M | 255.84M | 242.94M | 256.11M | 362M |
| Fixed Asset Turnover | 4.02x | 4.22x | 4.54x | 7.31x | 4.03x | 4.13x | 2.30x | 3.24x | 2.75x | 2.61x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 20.36M | 22M | 24.03M | 25.67M | 27.94M | 29M | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 0 | 0 | 0 | 15.06M | 32.32M | 40.37M | 42.99M | 41.02M | 0 |
| Other Non-Current Assets | 1.32M | 10.13M | 12.91M | 27.63M | 34.97M | 9.27M | 34.97M | 62.29M | 86.25M | 172M |
| Total Assets | 912.47M | 1.32B | 2.67B | 3.23B | 2.39B | 2.61B | 2.53B | 2.99B | 3B | 3.52B |
| Asset Turnover | 0.41x | 0.39x | 0.22x | 0.35x | 0.31x | 0.31x | 0.23x | 0.26x | 0.23x | 0.27x |
| Asset Growth % | -3.74% | 44.97% | 101.68% | 21.19% | -26.09% | 9.29% | -2.98% | 18% | 0.45% | 17.32% |
| Total Current Liabilities | 133.78M | 243.61M | 280.29M | 273M | 598.9M | 240.55M | 311.56M | 448.09M | 309.32M | 1.53B |
| Accounts Payable | 21.12M | 24.89M | 28.66M | 16.07M | 17.2M | 11.9M | 17.92M | 26.03M | 42.96M | 0 |
| Days Payables Outstanding | - | - | 5.75K | 1.34K | 525.46 | 400.75 | 463.39 | 1.04K | 1.4K | - |
| Short-Term Debt | 1.19M | 1.62M | 13.75M | 2.03M | 308.81M | 3.53M | 7.54M | 53.16M | 9.28M | 1.18B |
| Deferred Revenue (Current) | 51.28M | 125.34M | 160.26M | 118.27M | 108.38M | 97.71M | 90.58M | 151.13M | 78.99M | 74M |
| Other Current Liabilities | 24.19M | 25.15M | 29.27M | 37.36M | 73.03M | 38.81M | 49.18M | 67.73M | 69.61M | 277M |
| Current Ratio | 5.96x | 4.80x | 7.88x | 9.97x | 3.56x | 9.75x | 7.07x | 5.90x | 8.47x | 1.95x |
| Quick Ratio | 5.91x | 4.76x | 7.85x | 9.90x | 3.52x | 9.65x | 7.00x | 5.88x | 8.43x | 1.95x |
| Cash Conversion Cycle | - | - | -4.02K | 196.42 | 183.75 | 462.23 | 122.19 | -697.48 | -943.36 | - |
| Total Non-Current Liabilities | 679.12M | 713.88M | 1.2B | 1.28B | 1.05B | 1.6B | 1.65B | 2.16B | 2.11B | 1.5B |
| Long-Term Debt | 500.51M | 592.88M | 628.06M | 769.96M | 600.12M | 1.23B | 1.18B | 1.23B | 1.25B | 1.38B |
| Capital Lease Obligations | 72.36M | 0 | 0 | 0 | 0 | 19.43M | 178.94M | 170.88M | 161.81M | 262M |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 15.05M | 12.97M | 4.91M | 15.54M | 23.41M | 0 | 0 | 513.74M | 542.21M | -234M |
| Total Liabilities | 812.9M | 957.49M | 1.48B | 1.55B | 1.65B | 1.84B | 1.96B | 2.6B | 2.42B | 3.04B |
| Total Debt | 574.05M | 594.5M | 641.81M | 771.98M | 908.93M | 1.25B | 1.37B | 1.45B | 1.42B | 2.83B |
| Net Debt | 489.37M | 464.87M | 362.99M | 88.7M | 511.26M | 381.86M | 1.09B | 1.05B | 1.17B | 2.45B |
| Debt / Equity | 5.77x | 1.63x | 0.54x | 0.46x | 1.22x | 1.62x | 2.39x | 3.76x | 2.41x | 5.78x |
| Debt / EBITDA | - | 15.09x | - | 2.02x | - | - | - | - | - | - |
| Net Debt / EBITDA | - | 11.80x | - | 0.23x | - | - | - | - | - | - |
| Interest Coverage | -0.52x | 0.69x | -1.37x | 7.50x | -18.09x | -3.23x | -50.50x | -4.34x | -5.25x | -5.23x |
| Total Equity | 99.56M | 365.28M | 1.19B | 1.68B | 743.28M | 771.74M | 572.89M | 386.69M | 588.35M | 489M |
| Equity Growth % | -50.41% | 266.88% | 225% | 41.9% | -55.88% | 3.83% | -25.77% | -32.5% | 52.15% | -16.89% |
| Book Value per Share | 0.82 | 2.90 | 8.86 | 11.79 | 5.32 | 5.47 | 4.04 | 2.70 | 3.94 | 3.06 |
| Total Shareholders' Equity | 99.56M | 281.01M | 1.05B | 1.47B | 743.28M | 771.74M | 572.89M | 386.69M | 588.35M | 489M |
| Common Stock | 122K | 125K | 138K | 140K | 140K | 141K | 142K | 144K | 158K | 163K |
| Retained Earnings | -1.18B | -1.19B | -967.29M | -707.53M | -1.13B | -1.16B | -1.43B | -1.8B | -2.25B | -2.63B |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -30.36M | -31.76M | -32.02M | -25.29M | -21.07M | -32.67M | -57.48M | -32.65M | -30.81M | -25.28M |
| Minority Interest | 0 | 84.27M | 139.08M | 213.45M | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -112.11M | 174.15M | 602.89M | 345.72M | 35.89M | 30.8M | -274.37M | -307.51M | -500.95M | -268.58M |
| Operating CF Margin % | -30.07% | 33.87% | 100.54% | 30.8% | 4.92% | 3.8% | -46.71% | -39.04% | -71.04% | -28.45% |
| Operating CF Growth % | -630.67% | 255.34% | 246.19% | -42.66% | -89.62% | -14.19% | -990.84% | -12.08% | -62.9% | 46.38% |
| Net Income | -86.56M | -17.3M | 214.99M | 303.26M | -486.77M | -28.6M | -269.72M | -366.29M | -453.9M | -381.39M |
| Depreciation & Amortization | 9.03M | 8.35M | 12.53M | 15.99M | 17.16M | 19.56M | 22.11M | 22.5M | 19.65M | 20.25M |
| Stock-Based Compensation | 72.11M | 85.97M | 131.31M | 146.57M | 230.12M | 120.68M | 100.26M | 105.81M | 130.2M | 133.87M |
| Deferred Taxes | 10.74M | 14.07M | -290.52M | -7.1M | 313.27M | 25.31M | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 34.1M | 39.5M | 35.17M | 55.69M | 35.66M | 7.67M | -134.59M | 7.73M | 12.49M | -41.33M |
| Working Capital Changes | -151.53M | 43.56M | 499.41M | -168.71M | -73.56M | -113.82M | 7.57M | -77.26M | -209.39M | 0 |
| Change in Receivables | -89.36M | 15.72M | 514K | -44.18M | -22M | 5.05M | 36.36M | -72.06M | 5.59M | 0 |
| Change in Inventory | -590K | -2.49M | 1.4M | -5.41M | -1.26M | -2.84M | 2.77M | -6.39M | -5.07M | -13.67M |
| Change in Payables | -10.68M | 1.78M | -655K | -16.34M | -2.75M | -6M | 1.09M | 8.12M | 15.99M | -15.36M |
| Cash from Investing | 56.6M | -358.29M | -929.56M | -41.27M | 274.48M | 194.91M | -262.64M | -214.13M | -134.03M | -277.78M |
| Capital Expenditures | -11.53M | -37.86M | -17.65M | -36.28M | -41.05M | -17.9M | -20.1M | -23.8M | -45.28M | -51.44M |
| CapEx % of Revenue | 3.09% | 7.36% | 2.94% | 3.23% | 5.63% | 2.21% | 3.42% | 3.02% | 6.42% | 5.45% |
| Acquisitions | 4.47M | 2.51M | 4.04M | 5.38M | 5.93M | 5.95M | 254.08M | 22K | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 63.71M | -323.53M | -4.04M | -5.38M | -5.93M | -5.95M | 0 | -4.21M | -5.06M | -5.64M |
| Cash from Financing | 11.39M | 229.09M | 475.87M | 100.02M | -596.61M | 245.93M | -55.3M | 644.08M | 478.06M | 675.84M |
| Debt Issued (Net) | -3.07M | -23.98M | 0 | 97M | 0 | 313.57M | -50.69M | 86.9M | -44.67M | 0 |
| Equity Issued (Net) | 1000K | 1000K | 1000K | 1000K | -1000K | 1000K | 1000K | 1000K | 1000K | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | -34.39M | -90.55M | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 1.04M | -2.04M | 0 | -82.24M | -492.65M | -153.34M | -10.98M | 507.74M | 0 | 675.84M |
| Net Change in Cash | -44.11M | 44.95M | 149.19M | 404.47M | -285.62M | 471.53M | -592.72M | 122.79M | -157.19M | 130.18M |
| Free Cash Flow | -123.63M | 136.29M | 585.24M | 309.44M | -5.16M | 12.9M | -294.47M | -335.52M | -546.23M | -320.03M |
| FCF Margin % | -33.17% | 26.51% | 97.59% | 27.56% | -0.71% | 1.59% | -50.13% | -42.6% | -77.46% | -33.9% |
| FCF Growth % | -1418.47% | 210.24% | 329.4% | -47.13% | -101.67% | 350.16% | -2383.06% | -13.94% | -62.8% | 41.41% |
| FCF per Share | -1.02 | 1.08 | 4.37 | 2.17 | -0.04 | 0.09 | -2.08 | -2.34 | -3.65 | -2.00 |
| FCF Conversion (FCF/Net Income) | 1.86x | 503.32x | 2.20x | 1.24x | -0.08x | -1.08x | 1.02x | 0.84x | 1.10x | 0.70x |
| Interest Paid | 0 | 0 | 0 | 9.87M | 6.25M | 4.78M | 2.9M | 6.51M | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 9.04M | 25.86M | 38K | 5.01M | 48.33M | 0 | 0 |
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -40.22% | 0.15% | 35.27% | 19.37% | -36.6% | -3.78% | -40.12% | -76.34% | -93.1% | -70.73% |
| Return on Invested Capital (ROIC) | -2.67% | 3.28% | -3.87% | 16.51% | -8.53% | -1.88% | -21.82% | -17.08% | -22.24% | -12.18% |
| Gross Margin | 100% | 100% | 99.7% | 99.61% | 98.36% | 98.66% | 97.6% | 98.84% | 98.41% | 98.31% |
| Net Margin | -16.2% | 0.07% | 45.65% | 24.78% | -60.92% | -3.53% | -45.92% | -46.5% | -64.37% | -40.36% |
| Debt / Equity | 5.77x | 1.63x | 0.54x | 0.46x | 1.22x | 1.62x | 2.39x | 3.76x | 2.41x | 5.78x |
| Interest Coverage | -0.52x | 0.69x | -1.37x | 7.50x | -18.09x | -3.23x | -50.50x | -4.34x | -5.25x | -5.23x |
| FCF Conversion | 1.86x | 503.32x | 2.20x | 1.24x | -0.08x | -1.08x | 1.02x | 0.84x | 1.10x | 0.70x |
| Revenue Growth | 31.4% | 37.93% | 16.63% | 87.2% | -35.04% | 11.13% | -27.53% | 34.1% | -10.48% | 33.87% |
Explore detailed financial history, valuation models, and returns analysis
DCF models, peer multiples & analyst estimates
Historical returns with dividends reinvested
Yield, growth, payout safety & DRIP calculator
EPS trends, net income & profitability analysis
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of valuation, profitability & efficiency metrics