Pfizer Inc. (PFE) P/E Ratio History
Historical price-to-earnings valuation from 1990 to 2026
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PFE Valuation Context
How does the current P/E compare to historical and market benchmarks?
P/E Ratio Analysis
As of May 6, 2026, Pfizer Inc. (PFE) trades at a price-to-earnings ratio of 19.4x, with a stock price of $26.44 and trailing twelve-month earnings per share of $1.31.
The current P/E is roughly in line with its 5-year average of 19.3x. Over the past five years, PFE's P/E has ranged from a low of 8.0x to a high of 81.1x, placing the current valuation at the 80th percentile of its historical range.
Compared to the Healthcare sector median P/E of 22.2x, PFE is roughly in line with its sector peers. The sector includes 241 companies with P/E ratios ranging from 0.0x to 171.0x.
Relative to the broader market, PFE trades at a notable discount to the S&P 500 median P/E of 25.1x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our PFE DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
PFE P/E vs Peers
P/E ratio compared to closely matched public peers
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $544B | 39.0 | - | -58% | |
| $279B | 15.5Lowest | 0.73Best | +8% | |
| $365B | 87.0 | - | -1% | |
| $934B | 43.1 | 1.49 | +96% | |
| $116B | 16.5 | - | +178% | |
| $281B | 27.7 | 1.27 | +191%Best | |
| $278B | 20.2 | 1.32 | +22% | |
| $178B | 23.2 | 7.87 | +88% | |
| $166B | 351.3 | - | -92% | |
| $28B | 21.4 | - | -21% |
Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.
PFE Historical P/E Data (1990–2026)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Date | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2026 Q1 | Sun Mar 29 2026 00:00:00 GM | $27.03 | $1.31 | 20.6x | -18% |
| FY2025 Q4 | Wed Dec 31 2025 00:00:00 GM | $24.90 | $1.36 | 18.3x | -27% |
| FY2025 Q3 | Sun Sep 28 2025 00:00:00 GM | $23.76 | $1.72 | 13.8x | -45% |
| FY2025 Q2 | Sun Jun 29 2025 00:00:00 GM | $24.19 | $1.89 | 12.8x | -49% |
| FY2025 Q1 | Sun Mar 30 2025 00:00:00 GM | $25.21 | $1.38 | 18.3x | -27% |
| FY2024 Q4 | $26.53 | $1.41 | 18.8x | -25% | |
| FY2024 Q3 | Sun Sep 29 2024 00:00:00 GM | $29.09 | $0.74 | 39.3x | +57% |
| FY2023 Q4 | Sun Dec 31 2023 00:00:00 GM | $28.79 | $0.35 | 81.1x | +223% |
| FY2023 Q3 | Sun Oct 01 2023 00:00:00 GM | $33.17 | $1.82 | 18.2x | -27% |
| FY2023 Q2 | Sun Jul 02 2023 00:00:00 GM | $36.68 | $3.75 | 9.8x | -61% |
| FY2023 Q1 | Sun Apr 02 2023 00:00:00 GM | $40.80 | $5.07 | 8.0x | -68% |
| FY2022 Q4 | Sat Dec 31 2022 00:00:00 GM | $51.24 | $5.47 | 9.4x | -63% |
Average P/E for displayed period: 25.1x
Full PFE Stock Analysis
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Start ComparisonPFE — Frequently Asked Questions
Quick answers to the most common questions about buying PFE stock.
Is PFE stock overvalued or undervalued?
PFE trades at 19.4x P/E, near its 5-year average of 19.3x. The 80th percentile ranking places valuation within normal historical bounds.
How does PFE's valuation compare to peers?
Pfizer Inc. P/E of 19.4x compares to sector median of 22.2x. The discount suggests lower growth expectations or higher risk.
What is PFE's PEG ratio?
PFE PEG ratio is N/A. Above 2.0 indicates premium valuation relative to growth rate. Historical P/E data spans 1990-2026.