Pfizer Inc. (PFE) P/E Ratio History
Fairly ValuedTrading at 20.5x, near 5Y avg of 19.8x · 80th percentile · In line with own history · Data 1990–2026
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P/E Ratio Analysis
As of September 23, 2026, Pfizer Inc. (PFE) trades at a price-to-earnings ratio of 20.5x, with a stock price of $27.93 and trailing twelve-month earnings per share of $0.76.
The current P/E is roughly in line with its 5-year average of 19.8x. Over the past five years, PFE's P/E has ranged from a low of 8.0x to a high of 81.1x, placing the current valuation at the 80th percentile of its historical range.
Compared to the Healthcare sector median P/E of 24.0x, PFE is roughly in line with its sector peers. The sector includes 225 companies with P/E ratios ranging from 0.0x to 174.5x.
Relative to the broader market, PFE trades roughly in line with the S&P 500 median P/E of 25.5x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our PFE DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
PFE Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
PFE P/E vs Peers
Vaccines and plasma-derived therapies peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $648B | 24.4 | 1.64 | +91% | |
| $373B | 20.7 | 0.98 | +8% | |
| $469B | 111.9 | - | -1% | |
| $1.1T | 51.0 | 1.77 | +96% | |
| $127B | 18.0 | - | +178% | |
| $130B | 12.9Lowest | 0.59 | +45% | |
| $269B | 19.6 | 1.28 | +22% | |
| $221B | 28.8 | 9.80 | +88% | |
| $190B | 22.5 | 0.17Best | +1684%Best | |
| $33B | 25.5 | - | -21% |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
PFE Historical P/E Data (1990–2026)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Period End | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2026 Q2 | Jun 28 2026 | $24.29 | $0.76 | 32.1x | +28% |
| FY2026 Q1 | Mar 29 2026 | $27.04 | $1.31 | 20.6x | -18% |
| FY2025 Q4 | Dec 31 2025 | $24.90 | $1.36 | 18.3x | -27% |
| FY2025 Q3 | Sep 28 2025 | $23.76 | $1.72 | 13.8x | -45% |
| FY2025 Q2 | Jun 29 2025 | $24.19 | $1.89 | 12.8x | -49% |
| FY2025 Q1 | Mar 30 2025 | $25.21 | $1.38 | 18.3x | -27% |
| FY2024 Q4 | - | $26.53 | $1.41 | 18.8x | -25% |
| FY2024 Q3 | Sep 29 2024 | $29.09 | $0.74 | 39.3x | +56% |
| FY2023 Q4 | Dec 31 2023 | $28.79 | $0.35 | 81.1x | +223% |
| FY2023 Q3 | Oct 01 2023 | $33.17 | $1.82 | 18.2x | -28% |
| FY2023 Q2 | Jul 02 2023 | $36.68 | $3.75 | 9.8x | -61% |
| FY2023 Q1 | Apr 02 2023 | $40.80 | $5.07 | 8.0x | -68% |
| FY2022 Q4 | Dec 31 2022 | $51.24 | $5.47 | 9.4x | -63% |
| FY2022 Q3 | Oct 02 2022 | $43.76 | $5.19 | 8.4x | -66% |
| FY2022 Q2 | Jul 03 2022 | $52.31 | $5.11 | 10.2x | -59% |
| FY2022 Q1 | Apr 03 2022 | $51.57 | $4.40 | 11.7x | -53% |
| FY2021 Q4 | Dec 31 2021 | $59.05 | $3.90 | 15.2x | -40% |
| FY2021 Q3 | Oct 03 2021 | $42.93 | $3.46 | 12.4x | -51% |
| FY2021 Q2 | Jul 04 2021 | $39.73 | $2.29 | 17.3x | -31% |
| FY2021 Q1 | Apr 04 2021 | $36.30 | $1.89 | 19.2x | -24% |
| FY2020 Q4 | - | $36.81 | $1.63 | 22.6x | -10% |
| FY2020 Q3 | Sep 27 2020 | $34.17 | $1.42 | 24.1x | -4% |
| FY2020 Q2 | Jun 28 2020 | $30.37 | $2.52 | 12.1x | -52% |
| FY2020 Q1 | Mar 29 2020 | $29.29 | $2.79 | 10.5x | -58% |
| FY2019 Q4 | - | $37.14 | $2.87 | 12.9x | -49% |
| FY2019 Q3 | Sep 29 2019 | $34.33 | $2.86 | 12.0x | -52% |
| FY2019 Q2 | Jun 30 2019 | $41.07 | $2.19 | 18.8x | -25% |
| FY2019 Q1 | Mar 31 2019 | $40.26 | $1.95 | 20.6x | -18% |
| FY2018 Q4 | Dec 31 2018 | $41.38 | $1.86 | 22.2x | -12% |
| FY2018 Q3 | Sep 30 2018 | $41.78 | $3.95 | 10.6x | -58% |
| FY2018 Q2 | Jul 01 2018 | $34.39 | $3.73 | 9.2x | -63% |
| FY2018 Q1 | Apr 01 2018 | $33.64 | $3.59 | 9.4x | -63% |
| FY2017 Q4 | Dec 31 2017 | $34.33 | $3.51 | 9.8x | -61% |
| FY2017 Q3 | Oct 01 2017 | $33.84 | $1.62 | 20.9x | -17% |
| FY2017 Q2 | Jul 02 2017 | $31.84 | $1.36 | 23.3x | -7% |
| FY2017 Q1 | Apr 02 2017 | $32.43 | $1.19 | 27.4x | +9% |
| FY2016 Q4 | Dec 31 2016 | $30.79 | $1.17 | 26.4x | +5% |
| FY2016 Q3 | Oct 02 2016 | $32.11 | $1.01 | 31.9x | +27% |
| FY2016 Q2 | Jul 03 2016 | $33.72 | $1.13 | 29.8x | +18% |
| FY2016 Q1 | Apr 03 2016 | $28.48 | $1.22 | 23.3x | -7% |
| FY2015 Q4 | - | $30.60 | $1.11 | 27.5x | +9% |
| FY2015 Q3 | Sep 27 2015 | $30.23 | $1.33 | 22.7x | -10% |
| FY2015 Q2 | Jun 28 2015 | $32.15 | $1.41 | 22.8x | -9% |
| FY2015 Q1 | Mar 29 2015 | $32.73 | $1.44 | 22.7x | -10% |
| FY2014 Q4 | Dec 31 2014 | $29.53 | $1.42 | 20.8x | -17% |
| FY2014 Q3 | Sep 28 2014 | $28.17 | $1.62 | 17.4x | -31% |
| FY2014 Q2 | Jun 29 2014 | $28.13 | $1.59 | 17.7x | -30% |
| FY2014 Q1 | Mar 30 2014 | $30.22 | $3.12 | 9.7x | -61% |
| FY2013 Q4 | - | $29.04 | $3.14 | 9.2x | -63% |
| FY2013 Q3 | Sep 29 2013 | $27.38 | $3.60 | 7.6x | -70% |
| FY2013 Q2 | Jun 30 2013 | $26.55 | $3.64 | 7.3x | -71% |
| FY2013 Q1 | Mar 31 2013 | $27.36 | $2.09 | 13.1x | -48% |
| FY2012 Q4 | Dec 31 2012 | $23.77 | $1.95 | 12.2x | -52% |
| FY2012 Q3 | Sep 30 2012 | $23.56 | $1.29 | 18.3x | -27% |
| FY2012 Q2 | Jul 01 2012 | $21.80 | $1.34 | 16.3x | -35% |
| FY2012 Q1 | Apr 01 2012 | $21.47 | $1.24 | 17.3x | -31% |
| FY2011 Q4 | Dec 31 2011 | $20.51 | $1.28 | 16.0x | -36% |
| FY2011 Q3 | Oct 02 2011 | $16.76 | $1.45 | 11.6x | -54% |
| FY2011 Q2 | Jul 03 2011 | $19.67 | $1.08 | 18.2x | -28% |
| FY2011 Q1 | Apr 03 2011 | $19.32 | $1.06 | 18.2x | -28% |
| FY2010 Q4 | Dec 31 2010 | $16.60 | $1.03 | 16.1x | -36% |
| FY2010 Q3 | Oct 03 2010 | $16.29 | $0.78 | 20.9x | -17% |
| FY2010 Q2 | Jul 04 2010 | $13.40 | $1.10 | 12.2x | -52% |
| FY2010 Q1 | Apr 04 2010 | $16.19 | $1.13 | 14.3x | -43% |
| FY2009 Q4 | - | $17.24 | $1.28 | 13.5x | -46% |
| FY2009 Q3 | Sep 27 2009 | $15.55 | $1.21 | 12.9x | -49% |
| FY2009 Q2 | Jun 28 2009 | $14.40 | $1.12 | 12.9x | -49% |
| FY2009 Q1 | Mar 29 2009 | $13.31 | $1.19 | 11.2x | -55% |
| FY2008 Q4 | Dec 31 2008 | $16.79 | $1.20 | 14.0x | -44% |
| FY2008 Q3 | Sep 28 2008 | $17.69 | $1.56 | 11.3x | -55% |
| FY2008 Q2 | Jun 29 2008 | $16.38 | $1.33 | 12.3x | -51% |
| FY2008 Q1 | Mar 30 2008 | $19.43 | $1.10 | 17.7x | -30% |
| FY2007 Q4 | Dec 31 2007 | $21.55 | $1.17 | 18.4x | -27% |
| FY2007 Q3 | Sep 30 2007 | $23.16 | $2.07 | 11.2x | -56% |
| FY2007 Q2 | Jul 01 2007 | $24.24 | $2.42 | 10.0x | -60% |
| FY2007 Q1 | Apr 01 2007 | $23.95 | $2.57 | 9.3x | -63% |
| FY2006 Q4 | Dec 31 2006 | $24.55 | $2.65 | 9.3x | -63% |
| FY2006 Q3 | Oct 01 2006 | $26.88 | $1.72 | 15.6x | -38% |
| FY2006 Q2 | Jul 02 2006 | $22.25 | $1.48 | 15.0x | -40% |
| FY2006 Q1 | Apr 02 2006 | $23.62 | $1.62 | 14.6x | -42% |
| FY2005 Q4 | Dec 31 2005 | $22.11 | $1.10 | 20.1x | -20% |
| FY2005 Q3 | Oct 02 2005 | $23.67 | $1.10 | 21.5x | -14% |
| FY2005 Q2 | Jul 03 2005 | $25.69 | $1.32 | 19.5x | -23% |
| FY2005 Q1 | Apr 03 2005 | $24.79 | $1.23 | 20.2x | -20% |
| FY2004 Q4 | Dec 31 2004 | $25.49 | $1.49 | 17.1x | -32% |
| FY2004 Q3 | Sep 26 2004 | $28.12 | $1.20 | 23.5x | -7% |
| FY2004 Q2 | Jun 27 2004 | $32.06 | $1.05 | 30.6x | +22% |
| FY2004 Q1 | Mar 28 2004 | $32.51 | $0.19 | 173.6x | +590% |
| FY2003 Q4 | Dec 31 2003 | $33.49 | $0.65 | 51.7x | +106% |
| FY2003 Q3 | Sep 28 2003 | $28.97 | $1.03 | 28.1x | +12% |
| FY2003 Q2 | Jun 29 2003 | $33.18 | $1.12 | 29.6x | +18% |
| FY2003 Q1 | Mar 30 2003 | $30.15 | $1.91 | 15.8x | -37% |
| FY2002 Q4 | - | $28.98 | $1.46 | 19.8x | -21% |
| FY2002 Q3 | Sep 29 2002 | $27.09 | $1.31 | 20.7x | -18% |
| FY2002 Q2 | Jun 30 2002 | $33.18 | $1.26 | 26.3x | +5% |
| FY2002 Q1 | Mar 31 2002 | $37.67 | $1.24 | 30.4x | +21% |
| FY2001 Q4 | Dec 31 2001 | $37.78 | $1.23 | 30.7x | +22% |
| FY2001 Q3 | Sep 30 2001 | $38.01 | $1.14 | 33.3x | +33% |
| FY2001 Q2 | Jul 01 2001 | $37.97 | $1.02 | 37.2x | +48% |
| FY2001 Q1 | Apr 01 2001 | $38.82 | $0.91 | 42.7x | +70% |
| FY2000 Q4 | Dec 31 2000 | $43.61 | $0.80 | 54.5x | +117% |
| FY2000 Q3 | Oct 01 2000 | $42.60 | $0.73 | 58.4x | +132% |
| FY2000 Q2 | Jul 02 2000 | $45.50 | $0.63 | 72.2x | +187% |
| FY2000 Q1 | Apr 02 2000 | $34.66 | $0.56 | 61.9x | +146% |
| FY1999 Q4 | Dec 31 1999 | $30.75 | $0.58 | 53.0x | +111% |
| FY1999 Q3 | Oct 03 1999 | $35.37 | $0.53 | 66.8x | +166% |
| FY1999 Q2 | Jul 04 1999 | $36.61 | $0.77 | 47.6x | +89% |
| FY1999 Q1 | Apr 04 1999 | $44.10 | $0.81 | 54.5x | +117% |
| FY1998 Q4 | - | $39.50 | $0.78 | 50.7x | +102% |
| FY1998 Q3 | Sep 27 1998 | $33.71 | $0.77 | 43.8x | +74% |
| FY1998 Q2 | Jun 28 1998 | $35.37 | $0.57 | 62.1x | +147% |
| FY1998 Q1 | Mar 29 1998 | $30.26 | $0.54 | 56.1x | +123% |
| FY1997 Q4 | Dec 31 1997 | $23.56 | $0.51 | 46.2x | +84% |
| FY1997 Q3 | Sep 28 1997 | $19.27 | $0.50 | 38.4x | +53% |
| FY1997 Q2 | Jun 29 1997 | $19.27 | $0.48 | 39.9x | +59% |
| FY1997 Q1 | Mar 30 1997 | $13.80 | $0.46 | 29.8x | +19% |
| FY1996 Q4 | - | $13.11 | $0.44 | 29.6x | +18% |
| FY1996 Q3 | Sep 29 1996 | $12.32 | $0.43 | 28.8x | +14% |
| FY1996 Q2 | Jun 30 1996 | $11.28 | $0.41 | 27.6x | +10% |
| FY1996 Q1 | Mar 31 1996 | $10.62 | $0.39 | 27.4x | +9% |
| FY1995 Q4 | Dec 31 1995 | $9.95 | $0.37 | 27.0x | +7% |
| FY1995 Q3 | Oct 01 1995 | $8.43 | $0.36 | 23.7x | -6% |
| FY1995 Q2 | Jul 02 1995 | $7.28 | $0.34 | 21.6x | -14% |
| FY1995 Q1 | Apr 02 1995 | $6.77 | $0.33 | 20.7x | -18% |
| FY1994 Q4 | Dec 31 1994 | $6.10 | $0.32 | 19.3x | -23% |
| FY1994 Q3 | Oct 02 1994 | $5.46 | $0.34 | 16.0x | -36% |
| FY1994 Q2 | Jul 03 1994 | $4.96 | $0.19 | 26.0x | +3% |
| FY1994 Q1 | Apr 03 1994 | $4.27 | $0.19 | 22.4x | -11% |
| FY1993 Q4 | Dec 31 1993 | $5.45 | $0.18 | 30.1x | +20% |
| FY1993 Q3 | - | $4.70 | $0.10 | 45.5x | +81% |
| FY1993 Q2 | Jun 30 1993 | $5.29 | $0.23 | 22.7x | -10% |
| FY1993 Q1 | Mar 31 1993 | $4.92 | $0.21 | 23.1x | -8% |
| FY1992 Q4 | - | $5.73 | $0.19 | 29.6x | +18% |
| FY1992 Q3 | Sep 30 1992 | $5.90 | $0.19 | 31.0x | +23% |
| FY1992 Q2 | - | $5.77 | $0.19 | 30.3x | +21% |
| FY1992 Q1 | - | $5.49 | $0.19 | 28.9x | +15% |
| FY1991 Q4 | - | $6.64 | $0.19 | 34.9x | +39% |
| FY1991 Q3 | Sep 30 1991 | $5.14 | $0.23 | 22.5x | -10% |
| FY1991 Q2 | Jun 30 1991 | $4.38 | $0.22 | 20.1x | -20% |
| FY1991 Q1 | Mar 31 1991 | $4.23 | $0.21 | 20.3x | -19% |
| FY1990 Q4 | Dec 31 1990 | $3.19 | $0.20 | 16.1x | -36% |
Average P/E for displayed period: 25.1x
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Peer Comparison
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PFE — Frequently Asked Questions
Quick answers to the most common questions about buying PFE stock.
What is PFE's P/E ratio?
Pfizer Inc. (PFE) trailing twelve-month P/E ratio is 20.5x, based on TTM diluted EPS of $0.76. The 5-year average P/E is 19.8x and the historical range spans 8.0x to 81.1x.
Is PFE stock overvalued or undervalued?
PFE trades at 20.5x P/E, near its 5-year average of 19.8x. The 80th percentile ranking within the 8.0x–81.1x historical range places valuation within normal bounds.
Is PFE stock expensive?
PFE is fairly valued relative to its own history. The current P/E of 20.5x is near the 5-year average of 19.8x (80th percentile of historical range).
What is PFE's historical P/E range?
Over the past 5 years, PFE's P/E ratio has ranged from 8.0x to 81.1x, with a median of 17.3x and an average of 19.8x. The current P/E of 20.5x places the stock at the 80th percentile of this range. Full historical data spans 1990–2026.
How does PFE's P/E compare to the S&P 500?
PFE trades at 20.5x P/E versus the S&P 500 median of 25.5x. The 20% discount to the market suggests lower growth expectations or perceived higher risk.
How does PFE's valuation compare to Healthcare peers?
Pfizer Inc. P/E of 20.5x compares to the Healthcare sector median of 24.0x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.
What is PFE's PEG ratio?
PFE PEG ratio is N/A, based on a P/E of 20.5x and EPS growth of -3.5%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is PFE's earnings yield?
PFE earnings yield is 4.87%, the inverse of its 20.5x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.