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ASNDAscendis Pharma A/S
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ASND logoAscendis Pharma A/S(ASND)Earnings, Financials & Key Ratios

ASND•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutAscendis Pharma A/S, a biopharmaceutical company, focuses on developing therapeutics for unmet medical needs. The company offers SKYTROFA for treating patients with growth hormone deficiency (GHD). It also develops TransCon Growth Hormone (hGH) for pediatric GHD in Japan; TransCon hGH for adults with GHD; TransCon parathyroid hormone for adult hypoparathyroidism; and TransCon CNP for pediatric achondroplasia. In addition, the company develops TransCon toll like receptors 7/8 agonist for intratumoral delivery; and TransCon IL-2 ß/g for systemic delivery. The company was incorporated in 2006 and is headquartered in Hellerup, Denmark.Show more
  • Revenue$692M+90.2%
  • EBITDA-$114M+56.4%
  • Net Income-$219M+42.1%
  • EPS (Diluted)-3.62+44.6%
  • Gross Margin85.08%-3.1%
  • EBITDA Margin-16.47%+77.1%
  • Operating Margin-18.92%+75.3%
  • Net Margin-31.67%+69.5%

ASND Key Insights

Ascendis Pharma A/S (ASND) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 150.9%

✗Weaknesses

No significant weaknesses identified

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ASND Price & Volume

Ascendis Pharma A/S (ASND) stock price & volume — 10-year historical chart

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ASND Growth Metrics

Ascendis Pharma A/S (ASND) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years55.97%
5 Years150.93%
3 Years138.21%
TTM135.29%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM248.27%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM229.73%

Return on Capital

10 Years-80.27%
5 Years-106.73%
3 Years-134.54%
Last Year-51.87%

ASND Recent Earnings

Ascendis Pharma A/S (ASND) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 6/12 qtrs (50%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.32+70.6%
$0.19
Rev
$285M-7.8%
$309M
Q1 2026
Feb 11, 2026
Metric
Actual
Est
EPS
$0.64-966.7%
$0.06
Rev
$345M+18.0%
$292M
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$1.17-185.4%
$0.41
Rev
$250M-17.3%
$303M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.93+34.5%
$1.42
Rev
$186M-20.2%
$233M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.32vs $0.19+70.6%
$285Mvs $309M-7.8%
Q1 2026Feb 11, 2026
$0.64vs $0.06-966.7%
$345Mvs $292M+18.0%
Q4 2025Nov 12, 2025
$1.17vs $0.41-185.4%
$250Mvs $303M-17.3%
Q3 2025Aug 7, 2025
$0.93vs $1.42+34.5%
$186Mvs $233M-20.2%
Based on last 12 quarters of dataView full earnings history →

ASND Peer Comparison

Ascendis Pharma A/S (ASND) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IONS logoIONSIonis Pharmaceuticals, Inc.Direct Competitor12.25B74.12-31.1433.87%-30.87%-58.57%5.35
INCY logoINCYIncyte CorporationDirect Competitor19.62B98.2215.3221.22%26.71%29.31%0.01
ALKS logoALKSAlkermes plcDirect Competitor7.5B44.9931.46-5.25%9.78%8.82%0.04
JAZZ logoJAZZJazz Pharmaceuticals plcDirect Competitor14.09B224.66-38.474.88%0.66%0.71%1.26
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.7B21.629.4411.87%34.3%35.65%0.04
RARE logoRAREUltragenyx Pharmaceutical Inc.Direct Competitor2.7B27.44-4.7120.13%-91.03%-6.08%
AMRN logoAMRNAmarin Corporation plcProduct Competitor333.42M16.03-8.91-6.55%-15.64%-7.34%0.03
CLDX logoCLDXCelldex Therapeutics, Inc.Product Competitor2.16B32.43-8.32-78.63%-345.96%-50.72%0.00

Compare ASND vs Peers

Ascendis Pharma A/S (ASND) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IONS

Most directly comparable listed peer for ASND.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ASND against a more recognizable public peer.

Peer Set

Compare Top 5

vs IONS, INCY, ALKS, JAZZ

ASND Income Statement

Ascendis Pharma A/S (ASND) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
1.53M10.58M13.38M6.95M7.78M51.17M266.72M363.64M691.71M867.51M
Revenue Growth %
-66.78%591.57%26.41%-48.02%11.87%557.93%421.2%36.34%90.22%135.29%
Cost of Goods Sold
00003.52M12.14M44.4M44.26M103.18M102.62M
COGS % of Revenue
----45.29%23.72%16.64%12.17%14.92%-
Gross Profit
1.53M▲ 0%
10.58M▲ 591.6%
13.38M▲ 26.4%
6.95M▼ 48.0%
4.25M▼ 38.8%
39.04M▲ 817.4%
222.32M▲ 469.5%
319.38M▲ 43.7%
588.53M▲ 84.3%
764.89M▲ 0%
Gross Margin %
100%100%100%100%54.71%76.28%83.36%87.83%85.08%88.17%
Gross Profit Growth %
-66.78%591.57%26.41%-48.02%-38.8%817.44%469.52%43.66%84.27%-
Operating Expenses
113.07M165.34M240.09M337.57M456.05M600.85M677.86M598.15M719.42M771.82M
OpEx % of Revenue
7390.26%1562.59%1795.1%4855.07%5863.29%1174.13%254.15%164.49%104.01%-
Selling, General & Admin
13.48M25.06M48.47M76.67M160.18M215.85M258.79M284.55M435.92M496.78M
SG&A % of Revenue
881.18%236.81%362.42%1102.68%2059.4%421.8%97.03%78.25%63.02%-
Research & Development
99.59M140.28M191.62M260.9M295.87M379.62M413.45M307M283.5M271.47M
R&D % of Revenue
6509.09%1325.78%1432.68%3752.39%3803.9%741.83%155.02%84.42%40.99%-
Other Operating Expenses
000005.38M5.62M6.6M02M
Operating Income
-111.54M▲ 0%
-154.76M▼ 38.7%
-226.72M▼ 46.5%
-330.62M▼ 45.8%
-451.79M▼ 36.6%
-561.81M▼ 24.4%
-455.54M▲ 18.9%
-278.76M▲ 38.8%
-130.89M▲ 53.0%
-6.93M▲ 0%
Operating Margin %
-7290.26%-1462.59%-1695.1%-4755.07%-5808.59%-1097.85%-170.8%-76.66%-18.92%-0.8%
Operating Income Growth %
-52.96%-38.74%-46.5%-45.83%-36.65%-24.35%18.92%38.81%53.05%-
EBITDA
-110.85M-153.85M-220.05M-321.17M-436.4M-544.3M-436.63M-261.05M-113.9M10.46M
EBITDA Margin %
-7245.2%-1454.01%-1645.24%-4619.19%-5610.71%-1063.63%-163.7%-71.79%-16.47%1.21%
EBITDA Growth %
-53.51%-38.79%-43.03%-45.95%-35.88%-24.72%19.78%40.21%56.37%103.26%
D&A (Non-Cash Add-back)
689.46K908.17K6.67M9.45M15.39M17.51M18.91M17.71M17M17.4M
EBIT
-124.28M-130.36M-217.03M-417.26M-380.03M-547.13M-430.08M-307.74M-130.89M-24.34M
Net Interest Income
826K3.89M8.84M-106K-3.22M-23.26M-27.21M-51.14M-62.77M-95.7M
Interest Income
923K4.02M10.06M1.81M692K7.43M16.86M14.36M14.7M86.8M
Interest Expense
97K127K1.22M1.92M3.91M30.68M44.06M65.5M77.46M182.5M
Other Income/Expense
-12.83M24.27M8.47M-88.55M67.85M-16M-18.6M-94.48M-73.37M-160.87M
Pretax Income
-124.37M▲ 0%
-130.49M▼ 4.9%
-218.25M▼ 67.3%
-419.17M▼ 92.1%
-383.94M▲ 8.4%
-577.82M▼ 50.5%
-474.14M▲ 17.9%
-373.24M▲ 21.3%
-204.26M▲ 45.3%
-167.8M▲ 0%
Pretax Margin %
-8129.02%-1233.26%-1631.78%-6028.68%-4936.28%-1129.12%-177.77%-102.64%-29.53%-19.34%
Income Tax
-477K-394K-234K-219K-367K5.38M7.3M4.84M14.78M-674.4M
Effective Tax Rate %
0.38%0.3%0.11%0.05%0.1%-0.93%-1.54%-1.3%-7.23%401.9%
Net Income
-123.9M▲ 0%
-130.1M▼ 5.0%
-218.02M▼ 67.6%
-418.95M▼ 92.2%
-383.58M▲ 8.4%
-583.19M▼ 52.0%
-481.45M▲ 17.4%
-378.08M▲ 21.5%
-219.03M▲ 42.1%
506.6M▲ 0%
Net Margin %
-8097.84%-1229.53%-1630.03%-6025.53%-4931.56%-1139.63%-180.51%-103.97%-31.67%58.4%
Net Income Growth %
-80.86%-5%-67.58%-92.17%8.44%-52.04%17.45%21.47%42.07%248.27%
Net Income (Continuing)
-123.9M-130.1M-218.02M-418.95M-383.58M-583.19M-481.45M-378.08M-219.03M506.6M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-3.68▲ 0%
-3.17▲ 13.9%
-4.69▼ 47.9%
-8.28▼ 76.5%
-7.00▲ 15.5%
-10.40▼ 48.6%
-8.55▲ 17.8%
-6.53▲ 23.6%
-3.62▲ 44.6%
7.85▲ 0%
EPS Growth %
-42.64%13.86%-47.95%-76.55%15.46%-48.57%17.79%23.63%44.56%229.73%
EPS (Basic)
-3.68-3.17-4.69-8.28-7.00-10.40-8.55-6.53-3.62-
Diluted Shares Outstanding
33.63M41.09M46.51M50.62M54.77M56.07M56.29M57.89M60.61M64.52M
Basic Shares Outstanding
33.63M41.09M46.51M50.62M54.77M56.07M56.29M57.89M60.61M61.68M
Dividend Payout Ratio
----------

ASND Balance Sheet

Ascendis Pharma A/S (ASND) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
204.63M292.91M611.17M740.13M805.89M923.47M702.72M1.06B1.11B1.12B
Cash & Short-Term Investments
195.35M277.86M598.11M718.79M682.06M735.46M399.44M559.54M615.78M573.42M
Cash Only
195.35M277.86M598.11M584.52M446.27M444.77M392.16M559.54M615.78M573.42M
Short-Term Investments
000134.28M235.8M290.69M7.28M000
Accounts Receivable
188K6K804K387K2.2M11.91M35.87M166.28M157.63M196.81M
Days Sales Outstanding
44.850.2121.9420.32103.2484.9549.09166.983.1864.39
Inventory
000075.41M130.67M208.93M295.61M301.4M314.67M
Days Inventory Outstanding
----7.81K3.93K1.72K2.44K1.07K1.09K
Other Current Assets
2.19M2.62M4.61M6.96M20.99M13.72M19.9M11.16M03
Total Non-Current Assets
6.34M26.06M65.56M239.66M279.04M166.27M122.87M118.63M193.5M881.86M
Property, Plant & Equipment
2.56M4.33M45.07M108.11M126.05M129.09M110.63M98.71M146.42M136.06M
Fixed Asset Turnover
0.60x2.45x0.30x0.06x0.06x0.40x2.41x3.68x4.72x7.26x
Goodwill
3.5M3.5M3.5M3.5M3.5M3.5M3.5M3.5M3.49M3.69M
Intangible Assets
0002.22M1.78M1.33M924K533K214.91K0
Long-Term Investments
017.08M15.54M124.46M145.91M30.42M5.69M13.57M43.38M157.56M
Other Non-Current Assets
293K1.16M1.46M1.38M1.81M1.92M2.13M2.32M00
Total Assets
210.98M▲ 0%
318.97M▲ 51.2%
676.73M▲ 112.2%
979.79M▲ 44.8%
1.08B▲ 10.7%
1.09B▲ 0.4%
825.59M▼ 24.2%
1.18B▲ 42.9%
1.3B▲ 10.4%
2.01B▲ 0%
Asset Turnover
0.01x0.03x0.02x0.01x0.01x0.05x0.32x0.31x0.53x0.63x
Asset Growth %
11%51.18%112.16%44.78%10.73%0.44%-24.24%42.87%10.39%148.36%
Total Current Liabilities
23.77M38.92M47.99M52.8M100.36M716.78M736.51M907.86M1.07B1.13B
Accounts Payable
17.43M19.74M27.77M21.9M59.42M101.03M94.57M96.39M90.62M78.67M
Days Payables Outstanding
----6.16K3.04K777.49794.97320.56303.75
Short-Term Debt
00007M412.98M421.27M491.54M486.32M511.09M
Deferred Revenue (Current)
06.9M858K363K2.6M01.18M936K4.94M16.26M
Other Current Liabilities
0013.35M23.38M24.15M183.49M203.02M317.77M480.63M524.99M
Current Ratio
8.61x7.53x12.74x14.02x8.03x1.29x0.95x1.17x1.04x1.00x
Quick Ratio
8.61x7.53x12.74x14.02x7.28x1.11x0.67x0.84x0.76x0.72x
Cash Conversion Cycle
----1.76K976.35989.361.81K828.84846.75
Total Non-Current Liabilities
0031.63M88.28M100.93M109.61M234.78M377.34M395.83M388.95M
Long-Term Debt
000097.97M95.4M223M365.08M385.09M386.51M
Capital Lease Obligations
0030.72M85.12M97.97M95.4M84.62M000
Deferred Tax Liabilities
0000005.83M7.26M9.62M29.49M
Other Non-Current Liabilities
00908K3.16M-97.97M-95.4M-84.62M000
Total Liabilities
23.77M38.92M79.62M141.08M201.29M826.39M971.28M1.29B1.46B1.52B
Total Debt
0036.62M91.97M209.92M617.57M743.06M856.62M871.41M897.6M
Net Debt
-195.35M-277.86M-561.49M-492.54M-236.34M172.8M350.89M297.07M255.64M324.18M
Debt / Equity
--0.06x0.11x0.24x2.35x---1.84x
Debt / EBITDA
---------85.78x
Net Debt / EBITDA
---------30.98x
Interest Coverage
-1281.21x-1026.49x-177.75x-217.55x-97.17x-17.83x-9.76x-4.70x-1.69x-0.13x
Total Equity
187.21M▲ 0%
280.05M▲ 49.6%
597.11M▲ 113.2%
838.71M▲ 40.5%
883.63M▲ 5.4%
263.35M▼ 70.2%
-145.7M▼ 155.3%
-105.71M▲ 27.4%
-162.75M▼ 54.0%
488.48M▲ 0%
Equity Growth %
6%49.59%113.22%40.46%5.36%-70.2%-155.32%27.45%-53.97%266.11%
Book Value per Share
5.576.8212.8416.5716.134.70-2.59-1.83-2.697.57
Total Shareholders' Equity
187.21M280.05M597.11M838.71M883.63M263.35M-145.7M-105.71M-162.75M488.48M
Common Stock
4.97M5.66M6.44M7.22M7.65M7.67M7.75M8.15M8.32M8.39M
Retained Earnings
-263.21M-393.31M-611.32M-1.03B-1.24B-1.86B-2.28B-2.56B-2.7B-2.09B
Treasury Stock
0000-21K-149K-146K-113K-79.97K-35.04K
Accumulated OCI
22.78M42.45M79.9M133.02M3.78M3.45M721K1.78M-1.75M1.3M
Minority Interest
0000000000

ASND Cash Flow Statement

Ascendis Pharma A/S (ASND) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-95.1M-138.8M-175.94M-271.55M-417.65M-495.7M-467.36M-306.2M51.77M57.63M
Operating CF Margin %
-6215.62%-1311.8%-1315.41%-3905.48%-5369.62%-968.65%-175.23%-84.2%7.48%-
Operating CF Growth %
-58.03%-45.96%-26.75%-54.34%-53.8%-18.69%5.72%34.48%116.91%418.1%
Net Income
-123.9M-130.1M-218.02M-418.95M-383.58M-583.19M-481.45M-378.08M-219.03M506.6M
Depreciation & Amortization
734K880K6.69M9.45M15.39M17.96M18.91M17.71M17M17.4M
Stock-Based Compensation
9.71M19.65M37.49M53.17M66.83M64.18M66.66M95.51M060.66M
Deferred Taxes
-477K-394K-234K-219K-367K5.38M04.84M3.21M10.69M
Other Non-Cash Items
13.81M-30.55M-5.93M85.97M-68.2M12.45M24.77M60.98M182.44M-488.98M
Working Capital Changes
5.02M1.71M4.07M-964K-47.72M-12.47M-96.26M-107.16M68.16M-48.72M
Change in Receivables
99K182K-1.87M-2M-6.66M-11.53M-32.77M-118.61M14.97M-118.95M
Change in Inventory
-5.71M0-5.64M0-75.41M-55.27M-78.26M-86.68M-5.69M-21.53M
Change in Payables
10.76M8.26M7.51M00000-9.96M333.35K
Cash from Investing
-941K-2.65M-5.16M-291.2M-110.58M61.73M286.47M6.88M-8.15M-14.55M
Capital Expenditures
-941K-2.65M-5.16M-19.86M-23.7M-14.49M-2.44M-1.43M-8.15M-15.53M
CapEx % of Revenue
61.5%25.03%38.57%285.63%304.76%28.31%0.92%0.39%1.18%1.79%
Acquisitions
0000-10.19M00000
Investments
----------
Other Investing
0003.36M-530K9.54M288.92M950K0974.77K
Cash from Financing
124.72M203.27M493.59M602.65M351.39M396.77M134.29M443.93M34.89M16.75M
Debt Issued (Net)
00-4.04M-4.77M-6.43M496.93M125.82M122.79M-21.09M-27.45M
Equity Issued (Net)
133.11M216.38M480.25M580.54M346.28M-105.31M-1.81M309.91M66.93M38.52M
Dividends Paid
0000000000
Share Repurchases
0000-21.61M-105.31M-1.81M0-16.71M-53.39M
Other Financing
-8.39M-13.12M17.38M26.88M11.54M5.15M10.29M11.22M-10.95M5.68M
Net Change in Cash
15.02M▲ 0%
82.51M▲ 449.3%
320.24M▲ 288.1%
-13.59M▼ 104.2%
-138.25M▼ 917.4%
-1.5M▲ 98.9%
-52.6M▼ 3406.9%
167.38M▲ 418.2%
122.65M▼ 26.7%
42.66M▲ 0%
Free Cash Flow
-96.04M▲ 0%
-141.45M▼ 47.3%
-181.09M▼ 28.0%
-293.1M▼ 61.8%
-441.88M▼ 50.8%
-510.19M▼ 15.5%
-469.8M▲ 7.9%
-307.62M▲ 34.5%
43.62M▲ 114.2%
42.11M▲ 0%
FCF Margin %
-6277.12%-1336.83%-1353.98%-4215.45%-5681.19%-996.97%-176.14%-84.6%6.31%4.85%
FCF Growth %
-57.83%-47.28%-28.03%-61.85%-50.76%-15.46%7.92%34.52%114.18%119.07%
FCF per Share
-2.86-3.44-3.89-5.79-8.07-9.10-8.35-5.310.720.65
FCF Conversion (FCF/Net Income)
0.77x1.07x0.81x0.65x1.09x0.85x0.97x0.81x-0.24x0.08x
Interest Paid
00000015.67M000
Taxes Paid
0000000000

ASND Key Ratios

Ascendis Pharma A/S (ASND) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-68.11%-55.68%-49.71%-58.36%-44.54%-101.69%-818.43%---5641.9%
Return on Invested Capital (ROIC)
--5304.74%-899.32%-129.89%-68.22%-77.78%-106.54%-105.44%-69.07%-1.86%
Gross Margin
100%100%100%100%54.71%76.28%83.36%87.83%85.08%88.17%
Net Margin
-8097.84%-1229.53%-1630.03%-6025.53%-4931.56%-1139.63%-180.51%-103.97%-31.67%58.4%
Debt / Equity
--0.06x0.11x0.24x2.35x---1.84x
Interest Coverage
-1281.21x-1026.49x-177.75x-217.55x-97.17x-17.83x-9.76x-4.70x-1.69x-0.13x
FCF Conversion
0.77x1.07x0.81x0.65x1.09x0.85x0.97x0.81x-0.24x0.08x
Revenue Growth
-66.78%591.57%26.41%-48.02%11.87%557.93%421.2%36.34%90.22%135.29%
Related:ASND Dividend History·ASND Revenue History·ASND Price History·ASND P/E History·ASND Financial Ratios·ASND Institutional Holders

ASND Frequently Asked Questions

Ascendis Pharma A/S (ASND) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Ascendis Pharma A/S (ASND) reported $867.5M in revenue for fiscal year 2025. This represents a 5467% increase from $15.6M in 2012.

Ascendis Pharma A/S (ASND) grew revenue by 90.2% over the past year. This is strong growth.

Yes, Ascendis Pharma A/S (ASND) is profitable, generating $506.6M in net income for fiscal year 2025 (-31.7% net margin).

Dividend & Returns

Ascendis Pharma A/S (ASND) generated $42.1M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in ASND back in 2012?

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