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ASNDAscendis Pharma A/S
$227.31$14.2B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
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Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
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ASND logo

Ascendis Pharma A/S

ASND
NASDAQ · Biotechnology
$227.31
At close - Oct 1, 4:00 PM EDT - USD
Market Cap$14.12B
P/E-55.4x
52W High$282.15
Volume805.89K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Commercial Inflection Drives Cash Flow Surge Amidst Execution Risk

Ascendis Pharma is experiencing a dramatic commercial inflection, with Q2 2026 revenue growth accelerating to 118.2% year-over-year and operating income turning positive at $63.4M, driven by the ramp of SKYTROFA and initial YORVIPATH contributions. This revenu...

GrowthAccelerating
ProfitabilityModerate
ValuationExpensive
TechnicalsWeak
Explore valuation models
MARKET ACTION

ASND price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

6/12 Beats

EPS beat 6 of last 12 quarters

02

Valuation risk

-326% Peers

P/E is 326% below peer median

03

Market leadership

RS 45 · Lag

Laggard (Underperforming 55% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystConfirmed earnings · Nov 11
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue growth has accelerated to 118.2% year-over-year in Q2 2026, driving gross margins to a structurally high 90.6% and enabling operating income to expand to $63.4M, demonstrating clear operating leverage.

Analyst Consensus+39.3% target
Buy(26 analysts)
24 Buy2 Hold0 Sell

The Bull Case

Upside Catalysts

Transcon platform potential

Ascendis Pharma's Transcon platform is highlighted as a key driver, offering innovative solutions in drug delivery and development.

Rare disease pipeline

The company's focus on rare diseases presents significant growth opportunities due to high unmet medical needs and favorable pricing.

Recent trial successes

Positive results from recent clinical trials bolster confidence in the company's ability to bring new therapies to market.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 10/3/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
ASND+6.57%
S&P 500 (^GSPC)+11.83%
1-Year Return
ASND+11.37%
S&P 500 (^GSPC)+14.29%
3-Year Return
ASND+149.43%
S&P 500 (^GSPC)+78.33%
5-Year Return
ASND+40.10%
S&P 500 (^GSPC)+72.58%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E
-55.9x
Forward P/E
16.3x
EV/EBITDA
N/A
FCF YieldCash Flow
0.3%

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-55.9x
N/A
N/A
EV/EBITDA
N/A
N/A
N/A
Price/FCF
288.4x
296.3x
0th· Low
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$15.09-93.4%
Base (Fair)$235.06+3.2%
Bull$30.00-86.8%
$15.09 Bear$235.06 Base$30.00 Bull
Current Market Price: $227.31
Trades at a 3.3% discount to Base DCF ($235.06)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue
$692M+90.2% YoY
Net income
-$219M+42.1% YoY
Free cash flow
$44M+114.2% YoY
Operating margin
-18.9%+57.7 pts YoY
ROIC (TTM)-69.1%
Avg ROIC 5Y-
ROE (TTM)-
Piotroski Score5 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate6/12 (50%)
Revenue Beat Rate6/12 (50%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 13, 2026
$3.29+92.4%
vs $1.71
$387M+2.8%
vs $377M
Q2 2026
May 7, 2026
$0.32+70.6%
vs $0.19
$285M-7.8%
vs $309M
Q1 2026
Feb 11, 2026
-$0.64-966.7%
vs -$0.06
$345M+18.0%
vs $292M
Q4 2025
Nov 12, 2025
-$1.17-185.4%
vs -$0.41
$250M-17.3%
vs $303M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Defense World·4d ago
Ascendis Pharma A/S’s (ASND) “Overweight” Rating Reaffirmed at Cantor Fitzgerald

Ascendis Pharma A/S (NASDAQ: ASND - Get Free Report)'s stock had its "overweight" rating restated by equities research analysts at Cantor Fitzgerald in a report released on Friday, Benzinga reports. They presently have a $300.00 price target on the biotechnology company's stock. Cantor Fitzgerald's price objective points to a potential upside of 32.98% from the company's

Seeking Alpha·Sep 16, 2026
Ascendis Pharma: Back To Full Independence

Ascendis Pharma faces negative sentiment after Novo returned TransCon rights, compounding prior partner exits and pipeline disappointments. Despite pipeline contraction, ASND's approved products—Skytrofa, Yorvipath, and Yuviwel—show robust growth, and Yorvipath net sales should exceed $1.1 billion this year. Yuviwel's strong U.S. launch and favorable BioMarin settlement provide freedom to operate.

Seeking Alpha·Sep 15, 2026
Ascendis Pharma A/S (ASND) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Ascendis Pharma A/S (ASND) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Benzinga·Sep 15, 2026
Why Is Ascendis Pharma Stock Trading Lower on Tuesday?

Ascendis Pharma A/S (NASDAQ:ASND) shares are trading lower on Tuesday as investors digest news that the company will regain rights to certain TransCon technology-based programs and a share buyback.

Filtered for Ascendis Pharma A/SMore Headlines
04

Compare before deciding

Benchmark ASND against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Ascendis Pharma A/S (ASND)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ASND logoASNDAscendis Pharma A/SCurrent
$227.31$14.12B-55.4290.22%-31.67%——
IONS logoIONSIonis Pharmaceuticals, Inc.
$44.00$7.31B-18.4933.87%-64.64%-110.84%—
INCY logoINCYIncyte Corporation
$117.14$23.74B18.2721.22%27.71%29.7%—
ALKS logoALKSAlkermes plc
$40.54$6.8B28.35-5.25%3.96%3.72%—
JAZZ logoJAZZJazz Pharmaceuticals plc
$233.01$14.64B-39.904.88%20.45%21.37%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$19.89$3.41B8.6911.87%33.42%32.39%—

Compare ASND vs Peers

Ascendis Pharma A/S (ASND) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IONS

Most directly comparable listed peer for ASND.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ASND against a more recognizable public peer.

Peer Set

Compare Top 5

vs IONS, INCY, ALKS, JAZZ

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ASND Frequently Asked Questions

Ascendis Pharma A/S (ASND) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Ascendis Pharma A/S's revenue?

Ascendis Pharma A/S (ASND) reported $1.05B in revenue for fiscal year 2025. This represents a 6666% increase from $15.6M in 2012.

How fast is Ascendis Pharma A/S growing?

Ascendis Pharma A/S (ASND) grew revenue by 90.2% over the past year. This is strong growth.

Is ASND profitable?

Yes, Ascendis Pharma A/S (ASND) is profitable, generating $755.8M in net income for fiscal year 2025 (-31.7% net margin).

Dividend & Returns
What is Ascendis Pharma A/S's free cash flow?

Ascendis Pharma A/S (ASND) generated $336.9M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in ASND back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →