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ASND logoAscendis Pharma A/S(ASND)Earnings, Financials & Key Ratios

ASND•NASDAQ
$225.28
$13.83B mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutAscendis Pharma A/S, a biopharmaceutical company, focuses on developing therapeutics for unmet medical needs. The company offers SKYTROFA for treating patients with growth hormone deficiency (GHD). It also develops TransCon Growth Hormone (hGH) for pediatric GHD in Japan; TransCon hGH for adults with GHD; TransCon parathyroid hormone for adult hypoparathyroidism; and TransCon CNP for pediatric achondroplasia. In addition, the company develops TransCon toll like receptors 7/8 agonist for intratumoral delivery; and TransCon IL-2 ß/g for systemic delivery. The company was incorporated in 2006 and is headquartered in Hellerup, Denmark.Show more
  • Revenue$692M+90.2%
  • EBITDA-$114M+56.4%
  • Net Income-$219M+42.1%
  • EPS (Diluted)-3.62+44.6%
  • Gross Margin85.08%-3.1%
  • EBITDA Margin-16.47%+77.1%
  • Operating Margin-18.92%+75.3%
  • Net Margin-31.67%+69.5%
  • ROIC-69.07%+34.5%
  • Interest Coverage-1.69+64.0%
Analysis→Technical→

ASND Key Insights

Ascendis Pharma A/S (ASND) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 150.9%

✗Weaknesses

No significant weaknesses identified

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

ASND Price & Volume

Ascendis Pharma A/S (ASND) stock price & volume — 10-year historical chart

Loading chart...

ASND Growth Metrics

Ascendis Pharma A/S (ASND) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years55.97%
5 Years150.93%
3 Years138.21%
TTM97.4%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM39.77%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM39.76%

Return on Capital

10 Years-80.27%
5 Years-106.73%
3 Years-134.54%
Last Year-51.87%

ASND Recent Earnings

Ascendis Pharma A/S (ASND) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 6/12 qtrs (55%)
Q1 2026Latest
Feb 11, 2026
EPS
$0.64
Est $0.06
-966.7%
Revenue
$345M
Est $292M
+18.0%
Q4 2025
Nov 12, 2025
EPS
$1.17
Est $0.41
-185.4%
Revenue
$250M
Est $303M
-17.3%
Q3 2025
Aug 7, 2025
EPS
$0.93
Est $1.42
+34.5%
Revenue
$186M
Est $233M
-20.2%
Q2 2025
May 1, 2025
EPS
$1.66
Est $1.56
-6.4%
Revenue
$111M
Est $153M
-27.9%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q1 2026LatestFeb 11, 2026
$0.64vs $0.06-966.7%
$345Mvs $292M+18.0%
Q4 2025Nov 12, 2025
$1.17vs $0.41-185.4%
$250Mvs $303M-17.3%
Q3 2025Aug 7, 2025
$0.93vs $1.42+34.5%
$186Mvs $233M-20.2%
Q2 2025May 1, 2025
$1.66vs $1.56-6.4%
$111Mvs $153M-27.9%
Based on last 12 quarters of dataView full earnings history →

ASND Peer Comparison

Ascendis Pharma A/S (ASND) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IONS logoIONSIonis Pharmaceuticals, Inc.Direct Competitor12.44B75.25-31.6233.87%-30.87%-58.57%5.35
INCY logoINCYIncyte CorporationDirect Competitor19.47B97.4715.2121.22%26.71%29.31%6.96%0.01
ALKS logoALKSAlkermes plcDirect Competitor6.12B36.2525.35-5.25%16.37%14.45%7.85%0.04
JAZZ logoJAZZJazz Pharmaceuticals plcDirect Competitor13.32B212.26-36.354.88%0.66%0.71%9.74%1.26
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.78B22.3516.4331.85%24.94%28.47%4.16%0.07
RARE logoRAREUltragenyx Pharmaceutical Inc.Direct Competitor2.46B25.01-4.2920.13%-85.54%-9.11%
AMRN logoAMRNAmarin Corporation plcProduct Competitor301.6M14.50-8.06-6.55%-15.64%-7.34%2.24%0.03
CLDX logoCLDXCelldex Therapeutics, Inc.Product Competitor2.25B33.86-8.68-78.63%-172.53%-49.09%0.00

Compare ASND vs Peers

Ascendis Pharma A/S (ASND) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IONS

Most directly comparable listed peer for ASND.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ASND against a more recognizable public peer.

Peer Set

Compare Top 5

vs IONS, INCY, ALKS, JAZZ

ASND Income Statement

Ascendis Pharma A/S (ASND) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue1.53M10.58M13.38M6.95M7.78M51.17M266.72M363.64M691.71M
Revenue Growth %-66.78%591.57%26.41%-48.02%11.87%557.93%421.2%36.34%90.22%
Cost of Goods Sold00003.52M12.14M44.4M44.26M103.18M
COGS % of Revenue----45.29%23.72%16.64%12.17%14.92%
Gross Profit
1.53M▲ 0%
10.58M▲ 591.6%
13.38M▲ 26.4%
6.95M▼ 48.0%
4.25M▼ 38.8%
39.04M▲ 817.4%
222.32M▲ 469.5%
319.38M▲ 43.7%
588.53M▲ 84.3%
Gross Margin %100%100%100%100%54.71%76.28%83.36%87.83%85.08%
Gross Profit Growth %-66.78%591.57%26.41%-48.02%-38.8%817.44%469.52%43.66%84.27%
Operating Expenses113.07M165.34M240.09M337.57M456.05M600.85M677.86M598.15M719.42M
OpEx % of Revenue7390.26%1562.59%1795.1%4855.07%5863.29%1174.13%254.15%164.49%104.01%
Selling, General & Admin13.48M25.06M48.47M76.67M160.18M215.85M258.79M284.55M435.92M
SG&A % of Revenue881.18%236.81%362.42%1102.68%2059.4%421.8%97.03%78.25%63.02%
Research & Development99.59M140.28M191.62M260.9M295.87M379.62M413.45M307M283.5M
R&D % of Revenue6509.09%1325.78%1432.68%3752.39%3803.9%741.83%155.02%84.42%40.99%
Other Operating Expenses000005.38M5.62M6.6M0
Operating Income
-111.54M▲ 0%
-154.76M▼ 38.7%
-226.72M▼ 46.5%
-330.62M▼ 45.8%
-451.79M▼ 36.6%
-561.81M▼ 24.4%
-455.54M▲ 18.9%
-278.76M▲ 38.8%
-130.89M▲ 53.0%
Operating Margin %-7290.26%-1462.59%-1695.1%-4755.07%-5808.59%-1097.85%-170.8%-76.66%-18.92%
Operating Income Growth %-52.96%-38.74%-46.5%-45.83%-36.65%-24.35%18.92%38.81%53.05%
EBITDA-110.85M-153.85M-220.05M-321.17M-436.4M-544.3M-436.63M-261.05M-113.9M
EBITDA Margin %-7245.2%-1454.01%-1645.24%-4619.19%-5610.71%-1063.63%-163.7%-71.79%-16.47%
EBITDA Growth %-53.51%-38.79%-43.03%-45.95%-35.88%-24.72%19.78%40.21%56.37%
D&A (Non-Cash Add-back)689.46K908.17K6.67M9.45M15.39M17.51M18.91M17.71M17M
EBIT-124.28M-130.36M-217.03M-417.26M-380.03M-547.13M-430.08M-307.74M-130.89M
Net Interest Income826K3.89M8.84M-106K-3.22M-23.26M-27.21M-51.14M-62.77M
Interest Income923K4.02M10.06M1.81M692K7.43M16.86M14.36M14.7M
Interest Expense97K127K1.22M1.92M3.91M30.68M44.06M65.5M77.46M
Other Income/Expense-12.83M24.27M8.47M-88.55M67.85M-16M-18.6M-94.48M-73.37M
Pretax Income
-124.37M▲ 0%
-130.49M▼ 4.9%
-218.25M▼ 67.3%
-419.17M▼ 92.1%
-383.94M▲ 8.4%
-577.82M▼ 50.5%
-474.14M▲ 17.9%
-373.24M▲ 21.3%
-204.26M▲ 45.3%
Pretax Margin %-8129.02%-1233.26%-1631.78%-6028.68%-4936.28%-1129.12%-177.77%-102.64%-29.53%
Income Tax-477K-394K-234K-219K-367K5.38M7.3M4.84M14.78M
Effective Tax Rate %0.38%0.3%0.11%0.05%0.1%-0.93%-1.54%-1.3%-7.23%
Net Income
-123.9M▲ 0%
-130.1M▼ 5.0%
-218.02M▼ 67.6%
-418.95M▼ 92.2%
-383.58M▲ 8.4%
-583.19M▼ 52.0%
-481.45M▲ 17.4%
-378.08M▲ 21.5%
-219.03M▲ 42.1%
Net Margin %-8097.84%-1229.53%-1630.03%-6025.53%-4931.56%-1139.63%-180.51%-103.97%-31.67%
Net Income Growth %-80.86%-5%-67.58%-92.17%8.44%-52.04%17.45%21.47%42.07%
Net Income (Continuing)-123.9M-130.1M-218.02M-418.95M-383.58M-583.19M-481.45M-378.08M-219.03M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-3.68▲ 0%
-3.17▲ 13.9%
-4.69▼ 47.9%
-8.28▼ 76.5%
-7.00▲ 15.5%
-10.40▼ 48.6%
-8.55▲ 17.8%
-6.53▲ 23.6%
-3.62▲ 44.6%
EPS Growth %-42.64%13.86%-47.95%-76.55%15.46%-48.57%17.79%23.63%44.56%
EPS (Basic)-3.68-3.17-4.69-8.28-7.00-10.40-8.55-6.53-3.62
Diluted Shares Outstanding33.63M41.09M46.51M50.62M54.77M56.07M56.29M57.89M60.61M
Basic Shares Outstanding33.63M41.09M46.51M50.62M54.77M56.07M56.29M57.89M60.61M
Dividend Payout Ratio---------

ASND Balance Sheet

Ascendis Pharma A/S (ASND) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets204.63M292.91M611.17M740.13M805.89M923.47M702.72M1.06B1.11B
Cash & Short-Term Investments195.35M277.86M598.11M718.79M682.06M735.46M399.44M559.54M615.78M
Cash Only195.35M277.86M598.11M584.52M446.27M444.77M392.16M559.54M615.78M
Short-Term Investments000134.28M235.8M290.69M7.28M00
Accounts Receivable188K6K804K387K2.2M11.91M35.87M166.28M157.63M
Days Sales Outstanding44.850.2121.9420.32103.2484.9549.09166.983.18
Inventory000075.41M130.67M208.93M295.61M301.4M
Days Inventory Outstanding----7.81K3.93K1.72K2.44K1.07K
Other Current Assets2.19M2.62M4.61M6.96M20.99M13.72M19.9M11.16M0
Total Non-Current Assets6.34M26.06M65.56M239.66M279.04M166.27M122.87M118.63M193.5M
Property, Plant & Equipment2.56M4.33M45.07M108.11M126.05M129.09M110.63M98.71M146.42M
Fixed Asset Turnover0.60x2.45x0.30x0.06x0.06x0.40x2.41x3.68x4.72x
Goodwill3.5M3.5M3.5M3.5M3.5M3.5M3.5M3.5M3.49M
Intangible Assets0002.22M1.78M1.33M924K533K214.91K
Long-Term Investments017.08M15.54M124.46M145.91M30.42M5.69M13.57M43.38M
Other Non-Current Assets293K1.16M1.46M1.38M1.81M1.92M2.13M2.32M0
Total Assets
210.98M▲ 0%
318.97M▲ 51.2%
676.73M▲ 112.2%
979.79M▲ 44.8%
1.08B▲ 10.7%
1.09B▲ 0.4%
825.59M▼ 24.2%
1.18B▲ 42.9%
1.3B▲ 10.4%
Asset Turnover0.01x0.03x0.02x0.01x0.01x0.05x0.32x0.31x0.53x
Asset Growth %11%51.18%112.16%44.78%10.73%0.44%-24.24%42.87%10.39%
Total Current Liabilities23.77M38.92M47.99M52.8M100.36M716.78M736.51M907.86M1.07B
Accounts Payable17.43M19.74M27.77M21.9M59.42M101.03M94.57M96.39M90.62M
Days Payables Outstanding----6.16K3.04K777.49794.97320.56
Short-Term Debt00007M412.98M421.27M491.54M486.32M
Deferred Revenue (Current)06.9M858K363K2.6M01.18M936K4.94M
Other Current Liabilities0013.35M23.38M24.15M183.49M203.02M317.77M480.63M
Current Ratio8.61x7.53x12.74x14.02x8.03x1.29x0.95x1.17x1.04x
Quick Ratio8.61x7.53x12.74x14.02x7.28x1.11x0.67x0.84x0.76x
Cash Conversion Cycle----1.76K976.35989.361.81K828.84
Total Non-Current Liabilities0031.63M88.28M100.93M109.61M234.78M377.34M395.83M
Long-Term Debt000097.97M95.4M223M365.08M385.09M
Capital Lease Obligations0030.72M85.12M97.97M95.4M84.62M00
Deferred Tax Liabilities0000005.83M7.26M9.62M
Other Non-Current Liabilities00908K3.16M-97.97M-95.4M-84.62M00
Total Liabilities23.77M38.92M79.62M141.08M201.29M826.39M971.28M1.29B1.46B
Total Debt0036.62M91.97M209.92M617.57M743.06M856.62M871.41M
Net Debt-195.35M-277.86M-561.49M-492.54M-236.34M172.8M350.89M297.07M255.64M
Debt / Equity--0.06x0.11x0.24x2.35x---
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage-1281.21x-1026.49x-177.75x-217.55x-97.17x-17.83x-9.76x-4.70x-1.69x
Total Equity
187.21M▲ 0%
280.05M▲ 49.6%
597.11M▲ 113.2%
838.71M▲ 40.5%
883.63M▲ 5.4%
263.35M▼ 70.2%
-145.7M▼ 155.3%
-105.71M▲ 27.4%
-162.75M▼ 54.0%
Equity Growth %6%49.59%113.22%40.46%5.36%-70.2%-155.32%27.45%-53.97%
Book Value per Share5.576.8212.8416.5716.134.70-2.59-1.83-2.69
Total Shareholders' Equity187.21M280.05M597.11M838.71M883.63M263.35M-145.7M-105.71M-162.75M
Common Stock4.97M5.66M6.44M7.22M7.65M7.67M7.75M8.15M8.32M
Retained Earnings-263.21M-393.31M-611.32M-1.03B-1.24B-1.86B-2.28B-2.56B-2.7B
Treasury Stock0000-21K-149K-146K-113K-79.97K
Accumulated OCI22.78M42.45M79.9M133.02M3.78M3.45M721K1.78M-1.75M
Minority Interest000000000

ASND Cash Flow Statement

Ascendis Pharma A/S (ASND) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-95.1M-138.8M-175.94M-271.55M-417.65M-495.7M-467.36M-306.2M51.77M
Operating CF Margin %-6215.62%-1311.8%-1315.41%-3905.48%-5369.62%-968.65%-175.23%-84.2%7.48%
Operating CF Growth %-58.03%-45.96%-26.75%-54.34%-53.8%-18.69%5.72%34.48%116.91%
Net Income-123.9M-130.1M-218.02M-418.95M-383.58M-583.19M-481.45M-378.08M-219.03M
Depreciation & Amortization734K880K6.69M9.45M15.39M17.96M18.91M17.71M17M
Stock-Based Compensation9.71M19.65M37.49M53.17M66.83M64.18M66.66M95.51M0
Deferred Taxes-477K-394K-234K-219K-367K5.38M04.84M3.21M
Other Non-Cash Items13.81M-30.55M-5.93M85.97M-68.2M12.45M24.77M60.98M182.44M
Working Capital Changes5.02M1.71M4.07M-964K-47.72M-12.47M-96.26M-107.16M68.16M
Change in Receivables99K182K-1.87M-2M-6.66M-11.53M-32.77M-118.61M14.97M
Change in Inventory-5.71M0-5.64M0-75.41M-55.27M-78.26M-86.68M-5.69M
Change in Payables10.76M8.26M7.51M00000-9.96M
Cash from Investing-941K-2.65M-5.16M-291.2M-110.58M61.73M286.47M6.88M-8.15M
Capital Expenditures-941K-2.65M-5.16M-19.86M-23.7M-14.49M-2.44M-1.43M-8.15M
CapEx % of Revenue61.5%25.03%38.57%285.63%304.76%28.31%0.92%0.39%1.18%
Acquisitions0000-10.19M0000
Investments---------
Other Investing0003.36M-530K9.54M288.92M950K0
Cash from Financing124.72M203.27M493.59M602.65M351.39M396.77M134.29M443.93M34.89M
Debt Issued (Net)00-4.04M-4.77M-6.43M496.93M125.82M122.79M-21.09M
Equity Issued (Net)133.11M216.38M480.25M580.54M346.28M-105.31M-1.81M309.91M66.93M
Dividends Paid000000000
Share Repurchases0000-21.61M-105.31M-1.81M0-16.71M
Other Financing-8.39M-13.12M17.38M26.88M11.54M5.15M10.29M11.22M-10.95M
Net Change in Cash
15.02M▲ 0%
82.51M▲ 449.3%
320.24M▲ 288.1%
-13.59M▼ 104.2%
-138.25M▼ 917.4%
-1.5M▲ 98.9%
-52.6M▼ 3406.9%
167.38M▲ 418.2%
122.65M▼ 26.7%
Free Cash Flow
-96.04M▲ 0%
-141.45M▼ 47.3%
-181.09M▼ 28.0%
-293.1M▼ 61.8%
-441.88M▼ 50.8%
-510.19M▼ 15.5%
-469.8M▲ 7.9%
-307.62M▲ 34.5%
43.62M▲ 114.2%
FCF Margin %-6277.12%-1336.83%-1353.98%-4215.45%-5681.19%-996.97%-176.14%-84.6%6.31%
FCF Growth %-57.83%-47.28%-28.03%-61.85%-50.76%-15.46%7.92%34.52%114.18%
FCF per Share-2.86-3.44-3.89-5.79-8.07-9.10-8.35-5.310.72
FCF Conversion (FCF/Net Income)0.77x1.07x0.81x0.65x1.09x0.85x0.97x0.81x-0.24x
Interest Paid00000015.67M00
Taxes Paid000000000

ASND Key Ratios

Ascendis Pharma A/S (ASND) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-46.14%-68.11%-55.68%-49.71%-58.36%-44.54%-101.69%-818.43%--
Return on Invested Capital (ROIC)---5304.74%-899.32%-129.89%-68.22%-77.78%-106.54%-105.44%-69.07%
Gross Margin100%100%100%100%100%54.71%76.28%83.36%87.83%85.08%
Net Margin-1487.3%-8097.84%-1229.53%-1630.03%-6025.53%-4931.56%-1139.63%-180.51%-103.97%-31.67%
Debt / Equity---0.06x0.11x0.24x2.35x---
Interest Coverage-13745.40x-1281.21x-1026.49x-177.75x-217.55x-97.17x-17.83x-9.76x-4.70x-1.69x
FCF Conversion0.88x0.77x1.07x0.81x0.65x1.09x0.85x0.97x0.81x-0.24x
Revenue Growth-43.26%-66.78%591.57%26.41%-48.02%11.87%557.93%421.2%36.34%90.22%

ASND Frequently Asked Questions

Ascendis Pharma A/S (ASND) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Ascendis Pharma A/S (ASND) reported $717.8M in revenue for fiscal year 2025. This represents a 4506% increase from $15.6M in 2012.

Ascendis Pharma A/S (ASND) grew revenue by 90.2% over the past year. This is strong growth.

Ascendis Pharma A/S (ASND) reported a net loss of $227.7M for fiscal year 2025.

Dividend & Returns

Ascendis Pharma A/S (ASND) generated $42.8M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

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Ascendis Pharma A/S (ASND) financial analysis — history, returns, DCA and operating performance tools

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Earnings History

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

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