Ranked by reported Q4 2025 13F market value
Share of total reported institutional value in ATXS held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS LLC | 6.5M | $84.9M | 0.0% | 11.492% | 1.56% |
| 2 | BlackRock, Inc. | 3.8M | $50.2M | +9.9% | 6.792% | 0.00% |
| 3 | Magnetar Financial LLC | 3.4M | $44.9M | β | 6.080% | 0.44% |
| 4 | VANGUARD GROUP INC | 2.6M | $34.3M | -0.7% | 4.648% | 0.00% |
| 5 | UBS Group AG | 2.4M | $31.4M | +313.5% | 4.251% | 0.01% |
| 6 | DEUTSCHE BANK AG\ | 1.8M | $23.1M | +5187.5% | 3.124% | 0.01% |
| 7 | ALLIANCEBERNSTEIN L.P. | 1.7M | $22.7M | +2888.6% | 3.070% | 0.01% |
| 8 | BALYASNY ASSET MANAGEMENT LLC | 1.6M | $21.4M | β | 2.901% | 0.05% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 1.1M | $14.1M | +12.1% | 1.903% | 0.00% |
| 10 | Nantahala Capital Management, LLC | 1.1M | $14.0M | 0.0% | 1.895% | 0.54% |
| 11 | Qube Research & Technologies Ltd | 1.1M | $13.8M | β | 1.873% | 0.02% |
| 12 | KRYGER CAPITAL Ltd | 1.0M | $13.4M | β | 1.817% | 1.04% |
| 13 | Man Group plc | 977K | $12.8M | β | 1.732% | 0.02% |
| 14 | CITIGROUP INC | 927K | $12.1M | +2813.5% | 1.643% | 0.01% |
| 15 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 900K | $11.8M | +7.9% | 1.595% | 0.02% |
| 16 | STATE STREET CORP | 899K | $11.8M | +0.9% | 1.593% | 0.00% |
| 17 | Squarepoint Ops LLC | 883K | $11.6M | +5703.6% | 1.564% | 0.01% |
| 18 | TUDOR INVESTMENT CORP ET AL | 875K | $11.5M | β | 1.550% | 0.04% |
| 19 | SOROS FUND MANAGEMENT LLC | 873K | $11.4M | β | 1.548% | 0.15% |
| 20 | LMR Partners LLP | 840K | $11.0M | β | 1.488% | 0.03% |
| 21 | Vivaldi Asset Management, LLC | 831K | $10.9M | β | 1.473% | 0.66% |
| 22 | MORGAN STANLEY | 811K | $10.6M | -6.2% | 1.437% | 0.00% |
| 23 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 742K | $9.7M | β | 1.314% | 0.02% |
| 24 | GARDNER LEWIS ASSET MANAGEMENT L P | 740K | $9.7M | β | 1.310% | 2.45% |
| 25 | ALPINE ASSOCIATES MANAGEMENT INC. | 729K | $9.5M | β | 1.292% | 0.64% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in ATXS β a direct measure of their conviction.
Filings activity in ATXS during Q4 2025, grouped by how each filer changed its position.
Institutions that opened a new ATXS position in Q4 2025
Institutions that fully closed their ATXS position in Q4 2025
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q4 2025 | 139 | +22% | 96.43% | +38.82 pp | $685M | +67% |
| Q3 2025 | 114 | +5.6% | 57.61% | +14.17 pp | $409M | +33% |
| Q2 2025 | 108 | 6.9% | 43.44% | +0.77 pp | $308M | +1.8% |
| Q1 2025 | 116 | +4.5% | 42.67% | 29.82 pp | $303M | 41% |
| Q4 2024 | 111 | +7.8% | 72.49% | 13.77 pp | $515M | 16% |
| Q3 2024 | 103 | +6.2% | 86.26% | +17.35 pp | $612M | +25% |
| Q2 2024 | 97 | +3.2% | 68.91% | 41.58 pp | $489M | 38% |
| Q1 2024 | 94 | β | 110.49% | β | $784M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ATXS stock.
Based on Q4 2025 13F filings, institutional ownership of Astria Therapeutics, Inc. stands at 96.4%, held across 139 reporting institutions.
PERCEPTIVE ADVISORS LLC is the largest reported institutional holder of ATXS, with approximately 6,485,420 shares worth $0.08B as of Q4 2025.
Yes β 1 widely-followed marquee investor appear among the top 25 institutional holders of ATXS, including SOROS FUND MANAGEMENT LLC.
Our composite Smart Money Score for ATXS is 67 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
63 institutions opened new positions in ATXS during Q4 2025, while 38 fully exited. 64 added to existing positions and 12 trimmed.
ATXS institutional ownership rose by 38.82 percentage points quarter-over-quarter, with a net change of +25 holders.
The top 10 institutions account for 49.8% of all reported 13F value in ATXS, and the top 25 account for 74.9%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Astria Therapeutics, Inc. (ATXS) Institutional Ownership