The firm exhibits a persistent cash burn profile, with negative free cash flow reaching $12.5 million in 2025Q3 and stock-based compensation as high as $4.3 million per quarter masking true operational costs.
| Metric | TTM | Sep'25 | Sep'24 | Sep'23 | Sep'22 | Sep'21 | Sep'20 | Sep'19 | Sep'18 | Sep'17 | Sep'16 | Sep'15 | Sep'14 | Sep'13 | Sep'12 | Sep'11 | Sep'10 | Sep'09 | Sep'08 | Sep'07 | Sep'06 | Sep'05 | Sep'04 |
|---|
| Cash from Operations | -34.08M | -39.04M | -30.81M | -27.79M | -24.24M | -30.38M | -21.29M | -18.53M | -12.58M | -9.02M | -9.24M | -4.23M | -2.66M | -777.57K | -1.69M | -3.8M | -4.59M | -2.79M | -2.47M | -325.25K | -32.43K | -61.07K | -11.89K |
| Operating CF Margin % | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Operating CF Growth % | -79.09% | -26.72% | -10.89% | -14.63% | 20.23% | -42.73% | -14.9% | -47.25% | -39.54% | 2.38% | -118.52% | -58.95% | -242.01% | 54.07% | 55.47% | 17.24% | -64.37% | -12.96% | -660.66% | -902.99% | 46.9% | -413.64% | - |
| Net Income | -39.95M | -46.38M | -43M | -47.51M | -47.98M | -37.91M | -26.28M | -26.29M | -17.25M | -13.46M | -14.74M | -12.11M | -9.97M | -3.7M | -8.3M | -7.31M | -8.78M | -5.5M | -5.35M | -1.58M | -25.53K | -91.63K | -14.39K |
| Depreciation & Amortization | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.25K | 995 | 768 | 576 | 1.86K | 1.66K | 910 | 410 | 220 | 0 | 0 | 0 | 0 |
| Stock-Based Compensation | 10.6M | 11.55M | 9.44M | 16.37M | 18.38M | 8.23M | 4.88M | 6.43M | 5.52M | 4.14M | 5.06M | 1.63M | 637.92K | 1M | 302.21K | 1.27M | 770.05K | 812.34K | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.4M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 0 | 0 | 0 | 845K | 0 | 0 | 0 | 35.38K | 0 | -75.2K | -203.71K | 5.01M | 8.41M | 1.45M | 4.01M | 1.05M | 2.97M | 1.89M | 2.42M | 800K | 2.38K | 16K | 0 |
| Working Capital Changes | -4.73M | -4.22M | 2.75M | 2.5M | 5.36M | -706K | 116.52K | 1.3M | -846.67K | 382.81K | 640.07K | 1.24M | -336.25K | 465.91K | 2.29M | 1.18M | 450.94K | -181 | 460.36K | 454.74K | -9.27K | 14.55K | 2.5K |
| Change in Receivables | 1.71M | 1.64M | 260K | 484K | 5.94M | -4.29M | -2.21M | -772.39K | -231.1K | 54.44K | -2.51K | -76.84K | 0 | 0 | 809 | 37.01K | -37.82K | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | -1.93M | -5.38M | 5.3M | 497K | -914K | 751K | 465.72K | 683.8K | 38.23K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -3.02K | 0 | 0 | 0 | -3.31K | -1.24K | -1.08K | 0 | 0 | 0 | 0 |
| Capital Expenditures | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -3.02K | 0 | 0 | 0 | -3.31K | -1.24K | -1.08K | 0 | 0 | 0 | 0 |
| CapEx % of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Financing | 45.05M | 9.43M | 11.97M | 29.65M | 21.29M | 153.24M | 28.35M | 17.78M | 8.07M | 27.27M | 3.13M | 12.26M | 9.58M | 1.11M | 1.57M | 3.67M | 4.51M | 3.14M | 2.48M | 313K | 43.73K | 33.94K | 40K |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -34.76K | -88.14K | 10M | 250K | 581.5K | 750K | 1.42M | 1.2M | 1.35M | 0 | 20K | 0 | 0 |
| Equity Issued (Net) | 47.76M | 12.14M | 11.97M | 29.65M | 22M | 153.22M | 28.75M | 17.83M | 8.17M | 27.27M | 3.17M | 12.34M | 368.17K | 801.28K | 996.25K | 3.02M | 3.1M | 1.64M | 1.13M | 0 | 0 | 24K | 40K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -1.85M | -2.71M | 11.97M | 29.65M | -707K | 24K | -403.76K | -50K | -101.13K | 0 | 0 | 0 | -788.71K | 60K | -8.15K | -100K | 0 | 300K | 0 | 313K | 23.73K | 9.94K | 0 |
| Net Change in Cash | 10.97M | -29.61M | -18.84M | 1.87M | -2.95M | 122.86M | 7.06M | -745.01K | -4.51M | 18.25M | -6.1M | 8.03M | 6.92M | 333.71K | -123.34K | -129.97K | -86.33K | 344.64K | 6.33K | -12.25K | 11.3K | -27.13K | 28.11K |
| Free Cash Flow | -34.08M | -39.04M | -30.81M | -27.79M | -24.24M | -30.38M | -21.29M | -18.53M | -12.58M | -9.02M | -9.24M | -4.23M | -2.66M | -777.57K | -1.69M | -3.8M | -4.6M | -2.8M | -2.48M | -325.25K | -32.43K | -61.07K | -11.89K |
| FCF Margin % | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| FCF Growth % | 4.32% | -26.72% | -10.89% | -14.63% | 20.23% | -42.73% | -14.9% | -47.25% | -39.54% | 2.38% | -118.52% | -58.77% | -242.4% | 54.07% | 55.47% | 17.3% | -64.42% | -12.96% | -660.99% | -902.99% | 46.9% | -413.64% | - |
| FCF per Share | -0.38 | -0.46 | -0.37 | -0.35 | -0.32 | -0.44 | -0.37 | -0.38 | -0.28 | -0.22 | -0.26 | -0.23 | -0.27 | -0.10 | -0.24 | -0.60 | -0.86 | -0.55 | -0.50 | -0.07 | -0.01 | -0.01 | -0.01 |
| FCF Conversion (FCF/Net Income) | 0.85x | 0.84x | 0.72x | 0.58x | 0.51x | 0.80x | 0.81x | 0.70x | 0.72x | 0.67x | 0.63x | 0.35x | 0.23x | 0.21x | 0.20x | 0.52x | 0.52x | 0.51x | 0.46x | 0.21x | 1.27x | 0.67x | 0.83x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 123K | 125K | 300K | 136K | 327K | 140K | 22.66K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Binary Clinical Trial Outcomes
According to the provided financial data, the relationship between net income and operating cash flow is highly volatile, with the OCF/NI ratio fluctuating between 0.42 and 1.26, suggesting that non-cash items and working capital swings significantly distort the company's underlying cash burn profile each quarter.
The lack of a consistent correlation between net losses and cash outflows indicates that accrual-based accounting provides limited insight into the actual liquidity drain. Investors should monitor these fluctuations as they may imply that timing differences in clinical trial payments are masking the true, underlying rate of operational cash consumption.
As reported in quarterly filings, Anavex consistently generates negative free cash flow, with quarterly outflows reaching as high as $12.5 million in 2025Q3, confirming that the company remains entirely dependent on external financing to sustain its ongoing research and development activities without any offsetting product revenue.
The absence of positive free cash flow is expected for a clinical-stage entity, yet the magnitude of these outflows warrants caution regarding the company's long-term sustainability. This trajectory suggests that the firm's survival is tethered to its ability to access capital markets, which may become increasingly difficult if clinical milestones are not met.
Based on the reported figures, working capital changes have been erratic, swinging from a $4.6 million inflow in 2024Q3 to a $3.5 million outflow in 2025Q3, which highlights the unpredictable nature of the company's short-term cash requirements as it manages complex clinical trial vendor relationships.
These swings appear to reflect the timing of payments to clinical research organizations rather than operational efficiency. Such volatility suggests that the company's liquidity position is sensitive to the timing of trial-related milestones, which could create unexpected pressure on cash reserves during periods of high activity.
Data from recent SEC filings indicates that stock-based compensation has reached as high as $4.3 million in a single quarter, effectively acting as a non-cash expense that obscures the true economic cost of talent retention while simultaneously diluting the equity base of existing shareholders.
While stock-based compensation does not directly impact cash flow, it represents a significant hidden cost that investors must account for when evaluating the company's total burn rate. This practice suggests that management is prioritizing cash preservation by utilizing equity-linked incentives, which may lead to further dilution if the share price remains under pressure.
Quick answers to the most common questions about buying AVXL stock.
Anavex Life Sciences Corp. (AVXL) generated $-39.0M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Anavex Life Sciences Corp. (AVXL) reported negative free cash flow of $39.0M in 2025, indicating capital requirements exceeded cash from operations.
Anavex Life Sciences Corp. (AVXL) spent $0.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.