C4 Therapeutics, Inc. (CCCC) Revenue History
Annual and quarterly revenue from 2018 to present
CCCC Revenue Over Time (2018–2025)
CCCC Revenue Growth History
5 of 7 years with positive growth- FY2018 revenue growth
- N/A
- FY2019 revenue growth
- +10.4%
- FY2020 revenue growth
- +55.3%
- FY2021 revenue growth
- +37.9%
- FY2022 revenue growth
- -32.1%
- FY2023 revenue growth
- -33.3%
- FY2024 revenue growth
- +71.4%
- FY2025 revenue growth
- +1.0%
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $6.2M | -15.0% |
| Q4 2025 | $11.0M | +112.8% |
| Q3 2025 | $11.2M | -26.9% |
| Q2 2025 | $6.5M | -46.2% |
| Q1 2025 | $7.2M | +138.2% |
| Q4 2024 | $5.2M | +58.8% |
| Q3 2024 | $15.4M | +38.7% |
| Q2 2024 | $12.0M | +350.7% |
Multi-year avg. share of annual revenue by fiscal quarter
CCCC Revenue Analysis (2018–2025)
Current Revenue & Growth
As of June 29, 2026, C4 Therapeutics, Inc. (CCCC) generated trailing twelve-month (TTM) revenue of $34.9 million, reflecting significant decline in growth of -15.0% year-over-year. The most recent quarter (Q1 2026) recorded $6.2 million in revenue, down 44.2% sequentially.
Historical Growth Trajectory
CCCC's 5-year compound annual growth rate (CAGR) stands at +1.6%, indicating moderate growth over time. The 3-year CAGR of +5.0% exceeds the 5-year average, indicating an acceleration in the most recent period. C4 Therapeutics, Inc.'s highest annual revenue of $45.8 million was recorded in 2021.
Peer Comparison
Compared to Healthcare sector peers — including ARVN (-79.1% YoY), KYMR (-12.6% YoY), and VRTX (+10.4% YoY) — CCCC has outperformed the peer group in revenue growth. Compare CCCC vs ARVN →
CCCC Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| CCCCCurrent | $35M | -15.0% | +1.6% | -290.7% | |
 ARVN | $263M | -79.1% | +58.9% | -43.8% | |
 KYMR | $39M | -12.6% | +2.9% | -891.3% | |
 VRTX | $12.1B | +10.4% | +14.2% | 39.4% | |
 AUPH | $283M | +20.6% | +41.4% | 37.1% |
CCCC Historical Revenue Data (2018–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $35.9M | +1.0% | $28.0M | 77.8% | $-104,489,000 | -290.7% |
| 2024 | $35.6M | +71.4% | $35.6M | 100.0% | $-119,614,000 | -336.1% |
| 2023 | $20.8M | -33.3% | $13.0M | 62.7% | $-139,031,000 | -669.8% |
| 2022 | $31.1M | -32.1% | $31.1M | 100.0% | $-129,534,000 | -416.6% |
| 2021 | $45.8M | +37.9% | $45.8M | 100.0% | $-82,134,000 | -179.4% |
| 2020 | $33.2M | +55.3% | $-45,245,000 | -136.3% | $-60,449,000 | -182.1% |
| 2019 | $21.4M | +10.4% | $21.4M | 100.0% | $-35,452,000 | -165.8% |
| 2018 | $19.4M | - | $-9,228,000 | -47.7% | $-16,389,000 | -84.6% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
8+ years return with dividends reinvested.
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Peer Comparison
Compare growth, multiples, and margins vs sector.
CCCC — Frequently Asked Questions
Quick answers to the most common questions about buying CCCC stock.
Is CCCC's revenue growth accelerating or slowing?
CCCC revenue is declining -15.0% year-over-year. TTM revenue fell to $35M, contrasting with the 5-year CAGR of +1.6%. The reversal reflects either macro headwinds or company-specific challenges.
What is CCCC's revenue history from 2018 to 2026?
C4 Therapeutics, Inc. (CCCC) revenue history spans 2018 to 2026. TTM revenue as of 2026 is $35M, growing at -15.0% YoY. The 5-year CAGR is +1.6%. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is CCCC's long-term revenue growth rate (CAGR)?
C4 Therapeutics, Inc.'s 5-year revenue CAGR of +1.6% reflects the variable nature of its business expansion. As of 2026, the current YoY growth rate of -15.0% is below this long-term average. CAGR is the most reliable measure of sustained revenue momentum for CCCC.
Why does CCCC's quarterly revenue fluctuate?
CCCC quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. C4 Therapeutics, Inc.'s revenue data from 2018 to 2026 shows full historical quarterly detail on this page.
How is CCCC's revenue distributed by segment?
CCCC reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does CCCC's revenue compare to industry peers?
C4 Therapeutics, Inc. (CCCC) with TTM revenue of $35M and -15.0% YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.