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CCCCC4 Therapeutics, Inc.
$4.39$364M
Overview & Verdict
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CCCC logoC4 Therapeutics, Inc.(CCCC)Earnings, Financials & Key Ratios

CCCC•NASDAQ
$4.39
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutC4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins for the treatment of cancer, neurodegenerative conditions, and other diseases. Its lead product candidate is CFT7455, an orally bioavailable MonoDAC degrader of protein that is in Phase 1/2 trial targeting IKZF1 and IKZF3 for multiple myeloma and non-Hodgkin lymphomas, including peripheral T-cell lymphoma and mantle cell lymphoma. The company is also developing CFT8634, an orally bioavailable BiDAC degrader of BRD9, a protein target for synovial sarcoma and SMARCB1-deleted solid tumors; CFT1946, an orally bioavailable BiDAC degrader targeting V600X mutant BRAF to treat melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies; CFT8919, an orally bioavailable, allosteric, and mutant-selective BiDAC degrader of epidermal growth factor receptor, or EGFR, with an L858R mutation in NSCLC; and earlier stage programs comprising RET degraders for the treatment of various cancers. C4 Therapeutics, Inc. has strategic collaborations with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; Biogen MA, Inc.; and Calico Life Sciences LLC. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.Show more
  • Revenue$36M+1.0%
  • EBITDA-$103M+13.0%
  • Net Income-$105M+0.3%
  • EPS (Diluted)-1.27+16.4%
  • Gross Margin77.81%-22.2%
  • EBITDA Margin-285.23%+13.8%
  • Operating Margin-290.68%+13.5%
  • Net Margin-292.08%+1.3%
  • ROE-44.44%+2.5%

CCCC Price & Volume

C4 Therapeutics, Inc. (CCCC) stock price & volume — 10-year historical chart

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Persistent R&D Burn Strains Clinical Development Runway

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical trial funding dependency

Key Thesis Takeaways

  • C4 Therapeutics remains in a high-risk, pre-commercial phase where revenue is entirely dependent on volatile, project-based milestones that fail to offset consistent quarterly operating losses exceeding $25M.
  • While the TORPEDO platform drives innovation, the company's reliance on external capital to fund R&D intensity—which consistently exceeds $22M per quarter—creates significant dilution risk for shareholders.
  • Investors should monitor the rapid depletion of cash reserves, which fell from $126.6M in 2023Q4 to $61.3M in 2026Q1, as the firm lacks a self-sustaining commercial product to stabilize its financial trajectory.

Verdict Logic

the company's cash and equivalents have declined to $61.3M as of 2026Q1, suggesting that a dilutive capital raise may be imminent to sustain its current clinical development programs.

CCCC Growth Metrics

C4 Therapeutics, Inc. (CCCC) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years1.61%
3 Years4.95%
TTM-12.37%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-0.51%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM19.05%

Return on Capital

10 Years-29.41%
5 Years-32.05%
3 Years-36.42%
Last Year-33.15%

CCCC Recent Earnings

C4 Therapeutics, Inc. (CCCC) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 9/12 qtrs (75%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.20+20.2%
$0.25
Rev
$6M+40.4%
$4M
Q1 2026
Feb 26, 2026
Metric
Actual
Est
EPS
$0.18+41.9%
$0.31
Rev
$11M+104.2%
$5M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.44+6.4%
$0.47
Rev
$11M+150.7%
$4M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.37+2.6%
$0.38
Rev
$6M-5.0%
$7M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.20vs $0.25+20.2%
$6Mvs $4M+40.4%
Q1 2026Feb 26, 2026
$0.18vs $0.31+41.9%
$11Mvs $5M+104.2%
Q4 2025Nov 6, 2025
$0.44vs $0.47+6.4%
$11Mvs $4M+150.7%
Q3 2025Aug 7, 2025
$0.37vs $0.38+2.6%
$6Mvs $7M-5.0%
Based on last 12 quarters of dataView full earnings history →

Latest CCCC News

Recent stock market news and headlines for C4 Therapeutics, Inc. (CCCC)

Seeking Alpha·Jun 18, 2026
C4 Therapeutics, Inc. (CCCC) Discusses Evolving Multiple Myeloma Treatments and the Role of IKZF1/3 Degraders Including Cemsidomide Transcript

C4 Therapeutics, Inc. (CCCC) Discusses Evolving Multiple Myeloma Treatments and the Role of IKZF1/3 Degraders Including Cemsidomide Transcript

Zacks Investment Research·Jun 18, 2026
Are Medical Stocks Lagging C4 Therapeutics (CCCC) This Year?

Here is how C4 Therapeutics, Inc. (CCCC) and Clene Inc. (CLNN) have performed compared to their sector so far this year.

Peers Comparison

Key metrics vs top competitors for C4 Therapeutics, Inc. (CCCC)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CCCC logoCCCCC4 Therapeutics, Inc.Current
$4.39$363.61M-3.461.02%-292.08%-44.44%—
ARVN logoARVNArvinas, Inc.
$8.00$516.17M-6.25-0.3%-247.54%-44.39%—
KYMR logoKYMRKymera Therapeutics, Inc.
$108.12$8.83B-29.30-16.72%-612.17%-25.02%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$327.79$9.47B-24.32-100%—-43.02%—
VRTX logoVRTXVertex Pharmaceuticals Incorporated
$491.34$124.98B32.079.57%35.4%23.93%—
AUPH logoAUPHAurinia Pharmaceuticals Inc.
$17.23$2.22B8.3220.38%99.97%64.48%—

Compare CCCC vs Peers

C4 Therapeutics, Inc. (CCCC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ARVN

Most directly comparable listed peer for CCCC.

Scale Benchmark

vs VRTX

Larger-name benchmark to compare CCCC against a more recognizable public peer.

Peer Set

Compare Top 5

vs ARVN, KYMR, PRAX, VRTX

CCCC SEC Filings & Documents

C4 Therapeutics, Inc. (CCCC) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 15, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

Apr 10, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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CCCC Frequently Asked Questions

C4 Therapeutics, Inc. (CCCC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is C4 Therapeutics, Inc.'s revenue?

C4 Therapeutics, Inc. (CCCC) reported $34.9M in revenue for fiscal year 2025. This represents a 80% increase from $19.4M in 2018.

How fast is C4 Therapeutics, Inc. growing?

C4 Therapeutics, Inc. (CCCC) grew revenue by 1.0% over the past year. Growth has been modest.

Is CCCC profitable?

C4 Therapeutics, Inc. (CCCC) reported a net loss of $103.8M for fiscal year 2025.

Dividend & Returns
What is CCCC's return on equity?

C4 Therapeutics, Inc. (CCCC) has a return on equity (ROE) of -44.4%. Negative ROE indicates the company is unprofitable.

What is C4 Therapeutics, Inc.'s free cash flow?

C4 Therapeutics, Inc. (CCCC) had negative free cash flow of $96.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CCCC back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →