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CCCC logoC4 Therapeutics, Inc.(CCCC)Earnings, Financials & Key Ratios

CCCC•NASDAQ
$2.93
$243M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutC4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins for the treatment of cancer, neurodegenerative conditions, and other diseases. Its lead product candidate is CFT7455, an orally bioavailable MonoDAC degrader of protein that is in Phase 1/2 trial targeting IKZF1 and IKZF3 for multiple myeloma and non-Hodgkin lymphomas, including peripheral T-cell lymphoma and mantle cell lymphoma. The company is also developing CFT8634, an orally bioavailable BiDAC degrader of BRD9, a protein target for synovial sarcoma and SMARCB1-deleted solid tumors; CFT1946, an orally bioavailable BiDAC degrader targeting V600X mutant BRAF to treat melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies; CFT8919, an orally bioavailable, allosteric, and mutant-selective BiDAC degrader of epidermal growth factor receptor, or EGFR, with an L858R mutation in NSCLC; and earlier stage programs comprising RET degraders for the treatment of various cancers. C4 Therapeutics, Inc. has strategic collaborations with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; Biogen MA, Inc.; and Calico Life Sciences LLC. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.Show more
  • Revenue$36M+1.0%
  • EBITDA-$103M+13.0%
  • Net Income-$105M+0.3%
  • EPS (Diluted)-1.27+16.4%
  • Gross Margin77.81%-22.2%
  • EBITDA Margin-285.23%+13.8%
  • Operating Margin-290.68%+13.5%
  • Net Margin-292.08%+1.3%
  • ROE-44.44%+2.5%
  • ROIC-33.48%+22.2%
  • Debt/Equity0.23-23.2%
Technical→

CCCC Key Insights

C4 Therapeutics, Inc. (CCCC) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Trading at only 0.9x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Shares diluted 19.5% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

CCCC Price & Volume

C4 Therapeutics, Inc. (CCCC) stock price & volume — 10-year historical chart

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CCCC Growth Metrics

C4 Therapeutics, Inc. (CCCC) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years1.61%
3 Years4.95%
TTM1.02%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM0.31%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM9.93%

Return on Capital

10 Years-29.41%
5 Years-32.05%
3 Years-36.42%
Last Year-33.15%

CCCC Recent Earnings

C4 Therapeutics, Inc. (CCCC) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 8/12 qtrs (67%)
Q1 2026Latest
Feb 26, 2026
EPS
$0.18
Est $0.31
+41.9%
Revenue
$11M
Est $5M
+104.2%
Q4 2025
Nov 6, 2025
EPS
$0.44
Est $0.47
+6.4%
Revenue
$11M
Est $4M
+150.7%
Q3 2025
Aug 7, 2025
EPS
$0.37
Est $0.38
+2.6%
Revenue
$6M
Est $7M
-5.0%
Q2 2025
May 7, 2025
EPS
$0.37
Est $0.48
+22.9%
Revenue
$7M
Est $4M
+104.5%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q1 2026LatestFeb 26, 2026
$0.18vs $0.31+41.9%
$11Mvs $5M+104.2%
Q4 2025Nov 6, 2025
$0.44vs $0.47+6.4%
$11Mvs $4M+150.7%
Q3 2025Aug 7, 2025
$0.37vs $0.38+2.6%
$6Mvs $7M-5.0%
Q2 2025May 7, 2025
$0.37vs $0.48+22.9%
$7Mvs $4M+104.5%
Based on last 12 quarters of dataView full earnings history →

CCCC Peer Comparison

C4 Therapeutics, Inc. (CCCC) competitors in Drug Discovery and Antibody Platforms — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ARVN logoARVNArvinas, Inc.Direct Competitor656.24M10.26-8.02-0.3%-30.77%-14.25%0.02
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor7.04B86.26-23.38-16.72%-6.12%-25.02%0.05
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor7.61B337.95-25.07-100%-58.74%0.00
VRTX logoVRTXVertex Pharmaceuticals IncorporatedProduct Competitor108.78B427.6527.919.57%35.4%23.93%0.21
AUPH logoAUPHAurinia Pharmaceuticals Inc.Product Competitor2.15B16.257.8520.38%101.47%49.4%0.13
IMVT logoIMVTImmunovant, Inc.Product Competitor5.83B28.67-10.50-47.07%0.00
BCAB logoBCABBioAtla, Inc.Product Competitor5.29M4.50-0.09-81.82%-29.8%
RVMD logoRVMDRevolution Medicines, Inc.Product Competitor32.12B151.07-25.39-83.22%0.10

Compare CCCC vs Peers

C4 Therapeutics, Inc. (CCCC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ARVN

Most directly comparable listed peer for CCCC.

Scale Benchmark

vs VRTX

Larger-name benchmark to compare CCCC against a more recognizable public peer.

Peer Set

Compare Top 5

vs ARVN, KYMR, PRAX, VRTX

CCCC Income Statement

C4 Therapeutics, Inc. (CCCC) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue19.36M21.38M33.2M45.78M31.1M20.76M35.58M35.95M
Revenue Growth %-10.42%55.25%37.93%-32.08%-33.25%71.44%1.02%
Cost of Goods Sold28.59M078.44M007.74M07.97M
COGS % of Revenue147.66%-236.3%--37.28%-22.19%
Gross Profit
-9.23M▲ 0%
21.38M▲ 331.7%
-45.24M▼ 311.6%
45.78M▲ 201.2%
31.1M▼ 32.1%
13.02M▼ 58.1%
35.58M▲ 173.3%
27.97M▼ 21.4%
Gross Margin %-47.66%100%-136.3%100%100%62.72%100%77.81%
Gross Profit Growth %-331.7%-311.61%201.19%-32.08%-58.13%173.32%-21.39%
Operating Expenses35.75M56.83M15.2M127.92M160.63M152.05M155.2M132.46M
OpEx % of Revenue184.64%265.81%45.8%279.39%516.56%732.56%436.15%368.49%
Selling, General & Admin7.16M8.77M15.2M33.25M42.79M42.08M42.12M36.2M
SG&A % of Revenue36.98%41.04%45.8%72.63%137.6%202.74%118.38%100.69%
Research & Development28.59M48.06M78.44M94.67M117.84M117.71M110.64M104.24M
R&D % of Revenue147.66%224.77%236.3%206.76%378.96%567.09%310.92%289.98%
Other Operating Expenses-7K0-78.44M00-7.74M2.44M-7.97M
Operating Income
-16.39M▲ 0%
-35.45M▼ 116.3%
-60.45M▼ 70.5%
-82.13M▼ 35.9%
-129.53M▼ 57.7%
-139.03M▼ 7.3%
-119.61M▲ 14.0%
-104.49M▲ 12.6%
Operating Margin %-84.64%-165.81%-182.1%-179.39%-416.56%-669.84%-336.15%-290.68%
Operating Income Growth %--116.32%-70.51%-35.87%-57.71%-7.33%13.97%12.64%
EBITDA-12.82M-33.86M-58.83M-80.64M-127.86M-131.29M-117.8M-102.53M
EBITDA Margin %-66.18%-158.35%-177.23%-176.13%-411.17%-632.56%-331.04%-285.23%
EBITDA Growth %--164.18%-73.77%-37.07%-58.55%-2.69%10.28%12.96%
D&A (Non-Cash Add-back)3.57M1.59M1.62M1.49M1.68M7.74M1.82M1.96M
EBIT-16.39M-33.3M-60.45M-81.75M-125.96M-129.84M-105.19M-104.87M
Net Interest Income685K1.83M-836K-1.76M1.36M8.44M14.43M0
Interest Income685K1.83M393K387K3.58M9.81M14.43M0
Interest Expense001.23M2.15M2.22M1.37M00
Other Income/Expense678K2.16M-5.26M-1.76M1.36M7.82M14.43M-384K
Pretax Income
-15.71M▲ 0%
-33.3M▼ 111.9%
-65.71M▼ 97.4%
-83.89M▼ 27.7%
-128.18M▼ 52.8%
-131.21M▼ 2.4%
-105.19M▲ 19.8%
-104.87M▲ 0.3%
Pretax Margin %-81.14%-155.72%-197.95%-183.23%-412.19%-632.17%-295.6%-291.74%
Income Tax0804K626K001.28M131K121K
Effective Tax Rate %0%-2.41%-0.95%0%0%-0.98%-0.12%-0.12%
Net Income
-15.71M▲ 0%
-34.1M▼ 117.0%
-66.33M▼ 94.5%
-83.89M▼ 26.5%
-128.18M▼ 52.8%
-132.49M▼ 3.4%
-105.32M▲ 20.5%
-104.99M▲ 0.3%
Net Margin %-81.14%-159.48%-199.83%-183.23%-412.19%-638.34%-295.96%-292.08%
Net Income Growth %--117.04%-94.54%-26.47%-52.79%-3.37%20.51%0.31%
Net Income (Continuing)-15.71M-34.1M-66.33M-83.89M-128.18M-132.49M-105.32M-104.99M
Discontinued Operations00000000
Minority Interest00000000
EPS (Diluted)
-1.06▲ 0%
-0.79▲ 25.5%
-1.54▼ 94.9%
-1.82▼ 18.2%
-2.62▼ 44.0%
-2.67▼ 1.9%
-1.52▲ 43.1%
-1.27▲ 16.4%
EPS Growth %-25.47%-94.94%-18.18%-43.96%-1.91%43.07%16.45%
EPS (Basic)-1.06-0.79-1.54-1.82-2.62-2.67-1.52-1.27
Diluted Shares Outstanding42.09M42.99M43.06M46.04M48.86M49.64M69.37M82.89M
Basic Shares Outstanding14.79M42.99M43.06M46.04M48.86M49.64M69.37M82.89M
Dividend Payout Ratio--------

CCCC Balance Sheet

C4 Therapeutics, Inc. (CCCC) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets123.53M96.77M381.01M325.69M287.56M271.19M257.77M258.11M
Cash & Short-Term Investments36.31M90.55M371.69M309.28M276.15M253.68M244.9M248.54M
Cash Only36.31M90.55M181.73M76.12M29.75M126.59M55.5M74.6M
Short-Term Investments00189.96M233.16M246.4M127.09M189.41M173.93M
Accounts Receivable86.44M4.62M4.48M5.72M1.47M11.8M3.1M2.4M
Days Sales Outstanding1.63K78.9249.345.5717.29207.4931.8224.38
Inventory0000-60.96M000
Days Inventory Outstanding--------
Other Current Assets000070.89M5.71M9.76M7.17M
Total Non-Current Assets22.96M21.49M19.13M181.08M143.28M105.26M91.83M100.97M
Property, Plant & Equipment20.38M18.92M16.55M35.05M77.52M71.09M63.38M45.28M
Fixed Asset Turnover0.95x1.13x2.01x1.31x0.40x0.29x0.56x0.79x
Goodwill00000000
Intangible Assets00000000
Long-Term Investments2.58M00142.2M60.96M28.01M22.36M0
Other Non-Current Assets02.58M2.58M3.82M4.8M6.17M6.1M55.69M
Total Assets
146.49M▲ 0%
118.26M▼ 19.3%
400.14M▲ 238.4%
506.76M▲ 26.6%
430.84M▼ 15.0%
376.45M▼ 12.6%
349.6M▼ 7.1%
359.07M▲ 2.7%
Asset Turnover0.13x0.18x0.08x0.09x0.07x0.06x0.10x0.10x
Asset Growth %--19.27%238.35%26.65%-14.98%-12.62%-7.13%2.71%
Total Current Liabilities23.95M33.64M43.85M51.25M44.55M42.77M45.18M33.03M
Accounts Payable1.15M5.38M5.68M4.51M1.17M1.45M1.33M858K
Days Payables Outstanding14.73-26.44--68.22-39.27
Short-Term Debt00002.29M006.37M
Deferred Revenue (Current)19.11M20.7M27.6M31.8M16.62M15.47M18.71M12.49M
Other Current Liabilities1.26M3.33M4.19M5.5M3.11M9.39M9.3M13.31M
Current Ratio5.16x2.88x8.69x6.36x6.46x6.34x5.71x7.81x
Quick Ratio5.16x2.88x8.69x6.36x7.82x6.34x5.71x7.81x
Cash Conversion Cycle--------
Total Non-Current Liabilities202.29M196.58M75.5M65.91M97.06M87.57M88.44M69.46M
Long-Term Debt0010.05M10.77M9.2M000
Capital Lease Obligations13.75M12.87M11.83M30.78M70.97M65.76M59.98M53.62M
Deferred Tax Liabilities-13.75M0000000
Other Non-Current Liabilities111M111M000000
Total Liabilities226.24M230.22M119.35M117.16M141.61M130.34M133.62M102.49M
Total Debt14.48M13.75M22.92M42.88M87.15M70.98M65.76M59.98M
Net Debt-21.83M-76.8M-158.81M-33.24M57.4M-55.61M10.26M-14.62M
Debt / Equity--0.08x0.11x0.30x0.29x0.30x0.23x
Debt / EBITDA--------
Net Debt / EBITDA--------
Interest Coverage---49.19x-38.11x-56.84x-94.57x--
Total Equity
-79.75M▲ 0%
-111.96M▼ 40.4%
280.79M▲ 350.8%
389.61M▲ 38.8%
289.23M▼ 25.8%
246.11M▼ 14.9%
215.99M▼ 12.2%
256.59M▲ 18.8%
Equity Growth %--40.39%350.79%38.75%-25.76%-14.91%-12.24%18.8%
Book Value per Share-1.89-2.606.528.465.924.963.113.10
Total Shareholders' Equity-79.75M-111.96M280.79M389.61M289.23M246.11M215.99M256.59M
Common Stock1K04K5K5K6K7K9K
Retained Earnings-83.39M-117.49M-183.82M-267.71M-395.89M-528.38M-633.7M-738.69M
Treasury Stock-6.14M0000000
Accumulated OCI-2.5M013K-775K-4.14M-127K53K50K
Minority Interest00000000

CCCC Cash Flow Statement

C4 Therapeutics, Inc. (CCCC) cash flow — operating, investing & free cash flow history

Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-16.98M55.61M-67.25M-86.97M-105.94M-106.84M-65.16M-98.69M
Operating CF Margin %-87.69%260.11%-202.59%-189.94%-340.68%-514.73%-183.11%-274.55%
Operating CF Growth %-427.51%-220.92%-29.32%-21.82%-0.85%39.01%-51.47%
Net Income-15.71M-34.1M-66.33M-83.89M-128.18M-132.49M-105.32M-104.99M
Depreciation & Amortization1.27M1.59M1.62M1.49M1.68M1.88M1.82M1.96M
Stock-Based Compensation582K1.64M3.43M21.51M30.02M27.23M29.66M19.1M
Deferred Taxes66K350K5.58M1.88M0000
Other Non-Cash Items2.37M1.14M1.63M2.13M7.32M3.48M1.03M14.52M
Working Capital Changes-5.56M84.98M-13.18M-30.09M-16.78M-6.94M7.65M-29.28M
Change in Receivables-84.94M81.81M139K-1.23M4.24M-10.33M8.7M701K
Change in Inventory-2.22M2.17M-1.58M-2.63M0000
Change in Payables578K4.23M467K-1.18M-3.33M273K-119K-468K
Cash from Investing36.92M-1.62M-190.5M-189.34M58.42M158.35M-51.27M-8.6M
Capital Expenditures-2.69M-1.35M-650K-1.28M-5.5M-1.71M-180K-607K
CapEx % of Revenue13.89%6.31%1.96%2.79%17.67%8.23%0.51%1.69%
Acquisitions063K189.85M188.06M-63.92M000
Investments--------
Other Investing39.61M0-189.85M-188.06M63.92M000
Cash from Financing1.96M244K348.93M171.4M1.15M45.49M45.34M126.4M
Debt Issued (Net)0011.97M00-12.5M00
Equity Issued (Net)2.02M-30K340.4M169.47M777K57.56M44.18M126.13M
Dividends Paid00000000
Share Repurchases-63K-30K-194K00-110K-194K-193K
Other Financing-63K274K-3.45M1.94M370K426K1.16M274K
Net Change in Cash
21.9M▲ 0%
54.24M▲ 147.7%
91.18M▲ 68.1%
-104.9M▼ 215.1%
-46.37M▲ 55.8%
97M▲ 309.2%
-71.09M▼ 173.3%
19.1M▲ 126.9%
Free Cash Flow
-19.67M▲ 0%
54.27M▲ 375.9%
-67.9M▼ 225.1%
-88.24M▼ 30.0%
-111.44M▼ 26.3%
-108.55M▲ 2.6%
-65.34M▲ 39.8%
-99.3M▼ 52.0%
FCF Margin %-101.58%253.8%-204.55%-192.73%-358.36%-522.96%-183.61%-276.24%
FCF Growth %-375.88%-225.12%-29.96%-26.28%2.59%39.81%-51.98%
FCF per Share-0.471.26-1.58-1.92-2.28-2.19-0.94-1.20
FCF Conversion (FCF/Net Income)1.08x-1.63x1.01x1.04x0.83x0.81x0.62x0.94x
Interest Paid00820K00990K00
Taxes Paid01.09M143K001M00

CCCC Key Ratios

C4 Therapeutics, Inc. (CCCC) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric20182019202020212022202320242025
Return on Equity (ROE)---78.58%-25.03%-37.76%-49.5%-45.58%-44.44%
Return on Invested Capital (ROIC)---37.17%-25.76%-27.64%-38.83%-43.05%-33.48%
Gross Margin-47.66%100%-136.3%100%100%62.72%100%77.81%
Net Margin-81.14%-159.48%-199.83%-183.23%-412.19%-638.34%-295.96%-292.08%
Debt / Equity--0.08x0.11x0.30x0.29x0.30x0.23x
Interest Coverage---49.19x-38.11x-56.84x-94.57x--
FCF Conversion1.08x-1.63x1.01x1.04x0.83x0.81x0.62x0.94x
Revenue Growth-10.42%55.25%37.93%-32.08%-33.25%71.44%1.02%

CCCC SEC Filings & Documents

C4 Therapeutics, Inc. (CCCC) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 10, 2026·SEC

Material company update

Apr 9, 2026·SEC

Material company update

Feb 26, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

FY 2025

May 7, 2025·SEC

CCCC Frequently Asked Questions

C4 Therapeutics, Inc. (CCCC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

C4 Therapeutics, Inc. (CCCC) reported $35.9M in revenue for fiscal year 2025. This represents a 86% increase from $19.4M in 2018.

C4 Therapeutics, Inc. (CCCC) grew revenue by 1.0% over the past year. Growth has been modest.

C4 Therapeutics, Inc. (CCCC) reported a net loss of $105.0M for fiscal year 2025.

Dividend & Returns

C4 Therapeutics, Inc. (CCCC) has a return on equity (ROE) of -44.4%. Negative ROE indicates the company is unprofitable.

C4 Therapeutics, Inc. (CCCC) had negative free cash flow of $99.3M in fiscal year 2025, likely due to heavy capital investments.

Explore More CCCC

C4 Therapeutics, Inc. (CCCC) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

→

Revenue History

Sales growth patterns & revenue breakdown

→

Financial Ratios

30 years of market, efficiency and balance-sheet ratios

→

Valuation

DCF intrinsic value, peer multiples & estimates

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