Operating cash flow averaged 0.83x net losses, with free cash flow burn peaking at -$57.6M in 2025Q2, and cumulative net losses of -$490.6M outpacing operating cash outflows by $85.4M over ten quarters.
Cullinan Therapeutics, Inc. (CGEM) cash flow statement — 8-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 |
|---|
| Cash from Operations | -159.25M | -175.75M | -145.3M | -134.28M | -126.66M | -43.43M | -29.77M | -20.9M | -13.55M |
| Operating CF Margin % | - | - | - | - | - | -229.28% | - | - | - |
| Operating CF Growth % | 14.89% | -20.95% | -8.21% | -6.01% | -191.63% | -45.89% | -42.47% | -54.23% | - |
| Net Income | -204.69M | -219.88M | -167.57M | -153.16M | 109.19M | -67.48M | -51.8M | -20.66M | -14.19M |
| Depreciation & Amortization | 316K | 311K | 306K | 310K | 93K | 53K | 62K | 70K | 43K |
| Stock-Based Compensation | 32.84M | 36.04M | 37.82M | 30.44M | 27.96M | 24.38M | 0 | 0 | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 3.1M | 0 | 0 | 0 |
| Other Non-Cash Items | -737K | -6.31M | -15.47M | -11.52M | -275.08M | 67K | 15.11M | -445K | 252K |
| Working Capital Changes | 13.02M | 14.08M | -389K | -339K | 11.18M | -3.54M | 6.85M | 135K | 345K |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 1.26M | -839K | -812K | -167K | -509K | -4.83M | 5.58M | 639K | 225K |
| Cash from Investing | 162.88M | 179.99M | -136.31M | 35.81M | 248.97M | -333.77M | -5.42M | -35.4M | -261K |
| Capital Expenditures | -11K | -49K | 0 | -208K | -1.13M | -589.23K | -10K | -20K | -261K |
| CapEx % of Revenue | - | - | - | - | - | 3.11% | - | - | - |
| Acquisitions | 0 | 0 | 0 | -36.01K | 275M | 923K | 1.45M | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | -38K | 0 | 0 | 36.01K | 91K | -333.77K | 0 | 0 | 0 |
| Cash from Financing | 2.19M | 1.09M | 266.19M | 40.75M | -25.93M | 268.78M | 140.14M | 85.72M | -29K |
| Debt Issued (Net) | 0 | 0 | 0 | 1.82M | -2.2M | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 2.19M | 1.09M | 262.65M | 38.39M | 8.39M | 267.27M | 140.14M | 85.72M | -20K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | 0 | 3.54M | 538K | -32.13M | 1.52M | 0 | 0 | -9K |
| Net Change in Cash | 5.82M | 5.33M | -15.43M | -57.72M | 96.38M | -108.42M | 104.95M | 29.42M | -13.84M |
| Free Cash Flow | -159.3M | -175.8M | -145.3M | -134.48M | -127.8M | -44.02M | -29.78M | -20.92M | -13.81M |
| FCF Margin % | - | - | - | - | - | -232.39% | - | - | - |
| FCF Growth % | 7.13% | -20.99% | -8.05% | -5.23% | -190.3% | -47.81% | -42.38% | -51.46% | - |
| FCF per Share | -2.59 | -2.98 | -2.70 | -3.24 | -2.74 | -0.99 | -0.68 | -20.55 | -17.26 |
| FCF Conversion (FCF/Net Income) | 0.78x | 0.80x | 0.87x | 0.88x | -1.14x | 0.66x | 0.57x | 1.04x | 0.95x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 37.8M | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying CGEM stock.
Cullinan Therapeutics, Inc. (CGEM) generated $-175.8M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Cullinan Therapeutics, Inc. (CGEM) reported negative free cash flow of $175.8M in 2025, indicating capital requirements exceeded cash from operations.
Cullinan Therapeutics, Inc. (CGEM) spent $0.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Cash runway and dilution risk
Metrics are mathematically derived from official filings.
Cash Conversion Reflects Non-Cash Charges
Operating cash flow averaged 0.83x net loss over the past ten quarters, with stock-based compensation of $8-10M quarterly bridging the gap, according to recent SEC filings.
The OCF/NI ratio consistently below 1.0 indicates that net losses are partially non-cash, primarily due to stock-based compensation. This suggests that cash burn is somewhat less severe than net income implies, but the persistent gap warrants monitoring as SBC dilutes shareholders without immediate cash outflow.
FCF Burn Accelerates with Pipeline
Free cash flow deteriorated from -$38.2M in 2024Q1 to -$38.2M in 2026Q2, with a peak burn of -$57.6M in 2025Q2, as reported in financial statements.
The FCF trajectory shows a general increase in quarterly burn, particularly in 2025Q2, likely tied to pivotal trial initiation. With no revenue, FCF margins are undefined, and the trend suggests escalating cash needs as programs advance, reinforcing the urgency for external capital.
Minimal CapEx Signals Asset-Light Model
Capital expenditures were essentially zero across all quarters, with only $11K in 2025Q4, indicating a virtual absence of fixed asset investment, based on reported figures.
The negligible CapEx underscores a reliance on outsourced manufacturing and CROs, typical for clinical-stage biotech. This implies that cash burn is driven by R&D and operating expenses rather than capital intensity, but it also means the company lacks tangible asset backing, increasing reliance on pipeline success.
Working Capital Swings Reflect Trial Timing
Working capital changes ranged from -$5.9M to +$6.1M quarterly, with positive swings in most recent quarters, as per the cash flow statement.
The variability in working capital suggests timing effects from clinical trial payments and vendor terms. Positive changes in recent quarters may indicate efficient payables management or prepayments, but the small magnitudes relative to burn imply limited liquidity buffer from working capital optimization.
No Capital Returns, All Cash to R&D
No dividends or buybacks were paid in any quarter, with all cash directed to operations, as disclosed in the cash flow data.
The absence of capital returns is consistent with a pre-revenue company conserving cash for clinical development. This deployment strategy prioritizes pipeline advancement, but the lack of shareholder returns and the high burn rate heighten the need for future financing, likely dilutive.
Cumulative Losses Outpace Cash Outflows
Over ten quarters, cumulative net losses totaled -$490.6M versus operating cash outflows of -$405.2M, a gap of $85.4M, according to the provided data.
The cumulative divergence between net income and operating cash flow is largely attributable to non-cash charges like stock-based compensation. This suggests that while cash burn is substantial, the economic cost to shareholders is higher when including dilution, and the company's cash runway is shorter than net losses alone might imply.
What Could Invalidate the Base Case
The cash flow statement obscures the full cost of stock-based compensation, which totaled $89.8M over ten quarters, potentially understating true shareholder dilution, as per the data.
While SBC is a non-cash expense, it represents real economic cost through dilution. The company's reported cash burn may appear manageable, but when factoring in SBC, the effective cash outflow per share is higher. Additionally, the lack of CapEx may understate future capital needs if the company must invest in manufacturing or infrastructure upon commercialization. Investors should monitor the cash runway closely, as the $88.3M cash position may not sustain operations beyond two quarters at current burn rates.