Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in CPRX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 18.8M | $464.9M | +0.8% | 15.341% | 0.01% |
| 2 | STATE STREET CORP | 6.9M | $169.9M | -0.7% | 5.608% | 0.01% |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 5.1M | $126.8M | — | 4.186% | 0.00% |
| 4 | AMERICAN CENTURY COMPANIES INC | 4.1M | $102.5M | +36.8% | 3.382% | 0.05% |
| 5 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 3.9M | $97.6M | -19.7% | 3.222% | 1.15% |
| 6 | DIMENSIONAL FUND ADVISORS LP | 3.4M | $84.9M | +14.5% | 2.802% | 0.02% |
| 7 | BANK OF AMERICA CORP /DE/ | 3.0M | $75.2M | +38.0% | 2.481% | 0.01% |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 3.0M | $73.6M | +2.5% | 2.429% | 0.00% |
| 9 | MORGAN STANLEY | 2.7M | $66.5M | -8.4% | 2.196% | 0.00% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.5M | $61.3M | — | 2.023% | 0.00% |
| 11 | RENAISSANCE TECHNOLOGIES LLC | 2.3M | $58.1M | -11.4% | 1.918% | 0.09% |
| 12 | ROYCE & ASSOCIATES LP | 2.1M | $51.7M | +9.4% | 1.708% | 0.51% |
| 13 | JANUS HENDERSON GROUP PLC | 2.0M | $49.5M | +16.2% | 1.633% | 0.02% |
| 14 | Boston Partners | 1.7M | $42.4M | +39.0% | 1.399% | 0.04% |
| 15 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.4M | $35.4M | +5.4% | 1.168% | 0.01% |
| 16 | NORTHERN TRUST CORP | 1.2M | $30.6M | +2.1% | 1.011% | 0.00% |
| 17 | KENNEDY CAPITAL MANAGEMENT, INC. | 1.2M | $29.7M | -0.8% | 0.980% | 0.63% |
| 18 | GOLDMAN SACHS GROUP INC | 1.0M | $25.6M | +5.6% | 0.846% | 0.00% |
| 19 | UBS Group AG | 986K | $24.4M | +51.9% | 0.806% | 0.00% |
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 962K | $23.8M | +334.2% | 0.786% | 0.00% |
| 21 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 955K | $23.7M | -40.9% | 0.781% | 0.01% |
| 22 | RAYMOND JAMES FINANCIAL INC | 890K | $21.6M | +5.7% | 0.727% | 0.01% |
| 23 | VICTORY CAPITAL MANAGEMENT INC | 867K | $21.5M | -2.0% | 0.708% | 0.01% |
| 24 | Fundsmith LLP | 845K | $20.9M | -74.9% | 0.690% | 0.16% |
| 25 | VANGUARD FIDUCIARY TRUST CO | 803K | $19.9M | — | 0.656% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in CPRX — a direct measure of their conviction.
Filings activity in CPRX during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 373 | +2.2% | 64.42% | +3.03 pp | $2.47B | +5.0% |
| Q4 2025 | 365 | +3.4% | 61.39% | +9.56 pp | $2.36B | +18% |
| Q3 2025 | 353 | 1.4% | 51.83% | 3.56 pp | $1.99B | 6.4% |
| Q2 2025 | 358 | +1.1% | 55.39% | 3.25 pp | $2.13B | 5.5% |
| Q1 2025 | 354 | +6.3% | 58.64% | +2.02 pp | $2.25B | +3.6% |
| Q4 2024 | 333 | +7.1% | 56.62% | +9.59 pp | $2.17B | +20% |
| Q3 2024 | 311 | +16% | 47.03% | +9.64 pp | $1.81B | +26% |
| Q2 2024 | 268 | — | 37.39% | — | $1.44B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CPRX stock.
Based on Q1 2026 13F filings, institutional ownership of Catalyst Pharmaceuticals, Inc. stands at 64.4%, held across 373 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of CPRX, with approximately 18,774,530 shares worth $0.46B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of CPRX, including RENAISSANCE TECHNOLOGIES LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for CPRX is 66 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
59 institutions opened new positions in CPRX during Q1 2026, while 51 fully exited. 237 added to existing positions and 77 trimmed.
CPRX institutional ownership rose by 3.03 percentage points quarter-over-quarter, with a net change of +8 holders.
The top 10 institutions account for 53.5% of all reported 13F value in CPRX, and the top 25 account for 72.9%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.