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ENSCEnsysce Biosciences, Inc.
$0.27$2M
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ENSC logoEnsysce Biosciences, Inc. (ENSC) Earnings History

Net Loss

9 years of earnings data (2017–2025) · Currently unprofitable on a TTM basis

TTM Net Income
-$12M
● Net Loss
TTM EPS (Diluted)
$-1.72
Per share, diluted
YoY EPS Growth
+12.9%
Strong
Net Margin
-200.8%
After-tax profitability
EPS Growth Rate (CAGR)
1YN/A
3YN/A
5YN/A
10YN/A
Operating Margin-202.1%
Gross MarginN/A
Return on Equity-0.0%
Return on Assets-0.0%
Record Annual Net Income$56,770FY2020
Record Quarterly EPS$21.60Q3 2020
Consecutive Profitable Years0years
Q1 2026
Net Income-$4M
EPS (Diluted)$-0.52
YoY Growth+12.9%Strong
QoQ Growth-28.5%Declining

Loading earnings history...

Ensysce Biosciences, Inc. (ENSC) Earnings Overview

As of June 23, 2026, Ensysce Biosciences, Inc. (ENSC) reported trailing twelve-month net income of -$12M, reflecting +12.9% year-over-year growth. The company earned $-1.72 per diluted share over the past four quarters, with a net profit margin of -200.8%.

Looking at the long-term picture, ENSC's historical earnings data spans multiple years. The company achieved its highest annual net income of $56,770 in fiscal 2020.

Ensysce Biosciences, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including COLL ($75M net income, 8.1% margin), PCRX ($9M net income, 1.0% margin), AVDL (-$278,000 net income, -28.9% margin), ENSC has room to improve margins relative to the peer group. Compare ENSC vs COLL →

ENSC Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
ENSC logoENSCCurrent
-$12M$-1.72-200.8%-0.0%+12.9%—
COLL logoCOLL
$75M$1.878.1%23.7%-7.0%
PCRX logoPCRX
$9M$0.231.0%1.0%+107.4%
AVDL logoAVDL
$-278,000$-0.00-28.9%-60.4%+74.5%
NKTR logoNKTR
-$158M$-6.39-297.1%-217.9%-12.1%
PRGO logoPRGO
-$1.8B$-13.10-33.5%-39.3%-723.2%
Best in group
Lowest in group

ENSC Historical Earnings Data (2017–2025)

9 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$10M-27.4%-$10M$-3.98-200.8%-202.1%
2024-$8M+24.7%-$7M$-4.57-153.3%-129.2%
2023-$11M+56.1%-$11M$-4.69-475.7%-480.4%
2022-$24M+16.9%-$24M$-139.44-957.9%-959.9%
2021-$29M-51330.8%-$20M$-355.68-823.6%-562.7%
2020$56,770+100.6%-$2M$0.561.4%-41.0%
2019-$10M-652.2%-$9M$0.24-572.7%-485.7%
2018-$1M-4205.5%$-959,000$-0.22--
2017$-31,193-$-147,000$-0.01--

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ENSC — Frequently Asked Questions

Quick answers to the most common questions about buying ENSC stock.

What is ENSC earnings per share (EPS)?

ENSC trailing twelve-month (TTM) diluted EPS is $-1.72, reflecting +12.9% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2017 to 2025 is available in the table on this page.

What is Ensysce Biosciences, Inc.'s net income?

Ensysce Biosciences, Inc. (ENSC) trailing twelve-month net income is $-12M as of 2025. Earnings grew +12.9% year-over-year.

Is ENSC profitable?

ENSC is not currently profitable on a TTM basis, reporting a net loss of $-12M. Net margin is -200.8%. Investors should monitor for a return to profitability.

What is ENSC's earnings growth rate?

ENSC compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2017 to 2025.

What are ENSC's profit margins?

Ensysce Biosciences, Inc. net profit margin is -200.8%, operating margin is -202.1%, and gross margin is N/A. Below-average margins reflect competitive or cost pressures. Return on Equity is -0.0%.

Is ENSC growing earnings?

ENSC is growing earnings steadily. YoY EPS growth of +12.9% is consistent with the 5-year CAGR of N/A. TTM net income is $-12M.

What was ENSC's best earnings year?

Ensysce Biosciences, Inc.'s highest annual net income on record is $56770.00, achieved in fiscal year 2020. Earnings history on this page spans 2017 to 2025 and includes all annual and quarterly figures.

What were ENSC's earnings last quarter?

ENSC's most recent reported quarter was Q1 2026. Net income was $-4M with diluted EPS of $-0.52. For a full breakdown of all quarters, see the quarterly earnings table on this page.

ENSC Earnings Over Time (2017–2025)

Net income & EPS — annual and quarterly view