Ensysce Biosciences, Inc. (ENSC) Stock Price History
Historical prices from 2018 to 2026
- 1M
- -14.4%
- 3M
- -56.0%
- YTD
- -71.1%
- 1Y
- -87.3%
- 3Y
- -80.1%
- 5Y
- -91.0%
Loading 10-year price history...
ENSC Historical Performance
ENSC Annual Returns
Year-by-year price performance · 2018–2026
- 2018 annual price return
- +2.8%
- 2019 annual price return
- +6.1%
- 2020 annual price return
- +19.3%
- 2021 annual price return
- -61.9%
- 2022 annual price return
- -99.1%
- 2023 annual price return
- -89.0%
- 2024 annual price return
- -51.1%
- 2025 annual price return
- -88.8%
- 2026 annual price return
- -33.7%
ENSC Stock Price Trajectory (2018–2026)
As of June 23, 2026, Ensysce Biosciences, Inc. (ENSC) trades at $0.27, representing a -87.3% return over the past year. The stock has delivered a -100.0% total return over five years (-91.0% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $86,364.00 on February 1, 2021. From this peak, ENSC has corrected -100.0%, currently trading 75% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers COLL (+13.3% 1Y), PCRX (-7.5% 1Y), and AVDL (+132.2% 1Y), ENSC has underperformed the peer group average. Compare ENSC vs COLL →
ENSC Historical Price Data · from 2018
Rows 1–50 of 2,080| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-22 | 0.27 | 0.28 | 0.27 | 0.27 | 861K | +0.63% |
| 2026-06-18 | 0.27 | 0.29 | 0.26 | 0.27 | 1.41M | +0.56% |
| 2026-06-17 | 0.28 | 0.28 | 0.27 | 0.27 | 462K | -2.95% |
| 2026-06-16 | 0.27 | 0.28 | 0.25 | 0.28 | 1.30M | +3.00% |
| 2026-06-15 | 0.26 | 0.28 | 0.25 | 0.27 | 1.69M | +7.44% |
| 2026-06-12 | 0.26 | 0.26 | 0.25 | 0.25 | 541K | -4.67% |
| 2026-06-11 | 0.25 | 0.27 | 0.25 | 0.26 | 1.31M | +3.74% |
| 2026-06-10 | 0.25 | 0.27 | 0.24 | 0.25 | 1.16M | 0.00% |
| 2026-06-09 | 0.25 | 0.26 | 0.24 | 0.25 | 1.11M | +0.40% |
| 2026-06-08 | 0.26 | 0.26 | 0.24 | 0.25 | 893K | -0.43% |
| 2026-06-05 | 0.26 | 0.26 | 0.24 | 0.25 | 158K | -14.79% |
| 2026-06-04 | 0.28 | 0.31 | 0.26 | 0.30 | 2.87M | +10.20% |
| 2026-06-03 | 0.26 | 0.28 | 0.25 | 0.27 | 796K | +3.44% |
| 2026-06-02 | 0.28 | 0.28 | 0.26 | 0.26 | 655K | -6.57% |
| 2026-06-01 | 0.27 | 0.29 | 0.27 | 0.28 | 972K | -0.36% |
| 2026-05-29 | 0.30 | 0.30 | 0.27 | 0.28 | 843K | -6.64% |
| 2026-05-28 | 0.29 | 0.31 | 0.28 | 0.30 | 445K | +0.33% |
| 2026-05-27 | 0.29 | 0.30 | 0.27 | 0.30 | 508K | +0.33% |
| 2026-05-26 | 0.31 | 0.32 | 0.30 | 0.30 | 570K | -2.06% |
| 2026-05-22 | 0.31 | 0.32 | 0.30 | 0.31 | 35K | -1.99% |
| 2026-05-21 | 0.31 | 0.31 | 0.29 | 0.31 | 681K | +0.48% |
| 2026-05-20 | 0.30 | 0.32 | 0.27 | 0.31 | 1.06M | +4.62% |
| 2026-05-19 | 0.30 | 0.30 | 0.28 | 0.30 | 659K | -6.53% |
| 2026-05-18 | 0.25 | 0.32 | 0.24 | 0.32 | 1.97M | +13.17% |
| 2026-05-15 | 0.26 | 0.29 | 0.25 | 0.28 | 813K | +1.05% |
| 2026-05-14 | 0.27 | 0.28 | 0.23 | 0.28 | 1.62M | -3.82% |
| 2026-05-13 | 0.30 | 0.31 | 0.28 | 0.29 | 1.86M | -8.94% |
| 2026-05-12 | 0.33 | 0.36 | 0.32 | 0.32 | 3.31M | -19.26% |
| 2026-05-11 | 0.38 | 0.40 | 0.30 | 0.39 | 87.81M | +11.94% |
| 2026-05-08 | 0.38 | 0.38 | 0.35 | 0.35 | 216K | -5.35% |
| 2026-05-07 | 0.40 | 0.40 | 0.37 | 0.37 | 224K | -5.13% |
| 2026-05-06 | 0.40 | 0.43 | 0.39 | 0.39 | 105K | -2.50% |
| 2026-05-05 | 0.42 | 0.44 | 0.40 | 0.40 | 159K | -4.08% |
| 2026-05-04 | 0.39 | 0.43 | 0.38 | 0.42 | 311K | +7.20% |
| 2026-05-01 | 0.38 | 0.39 | 0.34 | 0.39 | 370K | +4.68% |
| 2026-04-30 | 0.37 | 0.39 | 0.36 | 0.37 | 112K | +2.85% |
| 2026-04-29 | 0.37 | 0.39 | 0.36 | 0.36 | 247K | -5.64% |
| 2026-04-28 | 0.40 | 0.40 | 0.38 | 0.38 | 134K | +0.08% |
| 2026-04-27 | 0.40 | 0.41 | 0.36 | 0.38 | 569K | -7.63% |
| 2026-04-24 | 0.44 | 0.44 | 0.41 | 0.41 | 261K | -2.31% |
| 2026-04-23 | 0.44 | 0.44 | 0.40 | 0.42 | 261K | -2.12% |
| 2026-04-22 | 0.45 | 0.46 | 0.42 | 0.43 | 224K | -4.12% |
| 2026-04-21 | 0.49 | 0.49 | 0.44 | 0.45 | 287K | -6.69% |
| 2026-04-20 | 0.48 | 0.51 | 0.47 | 0.48 | 206K | -3.16% |
| 2026-04-17 | 0.51 | 0.54 | 0.49 | 0.50 | 274K | -4.07% |
| 2026-04-16 | 0.54 | 0.54 | 0.48 | 0.52 | 205K | -2.60% |
| 2026-04-15 | 0.53 | 0.54 | 0.50 | 0.54 | 98K | +2.90% |
| 2026-04-14 | 0.53 | 0.53 | 0.51 | 0.52 | 201K | -5.66% |
| 2026-04-13 | 0.47 | 0.60 | 0.45 | 0.55 | 520K | +18.67% |
| 2026-04-10 | 0.48 | 0.50 | 0.46 | 0.46 | 180K | -1.53% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
ENSC — Frequently Asked Questions
Quick answers to the most common questions about buying ENSC stock.
How has ENSC stock performed recently?
ENSC declined -87.3% over the past year, below its 5-year annualized CAGR of -91.0%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is ENSC's all-time high price?
Ensysce Biosciences, Inc. reached $86364.00 on 2021-02-01. The 52-week high is $2.75. Current 1-year return of -87.3% places the stock further from historical peaks.
Where can I download ENSC historical price data?
This page provides ENSC daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2018-2026, downloadable in CSV format.