Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in FBIO held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Opaleye Management Inc. | 1.0M | $2.9M | -4.4% | 2.713% | 0.38% |
| 2 | VANGUARD CAPITAL MANAGEMENT LLC | 966K | $2.7M | — | 2.515% | 0.00% |
| 3 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 507K | $1.4M | +11.9% | 1.319% | 0.00% |
| 4 | GEODE CAPITAL MANAGEMENT, LLC | 290K | $810K | +10.6% | 0.756% | 0.00% |
| 5 | NORTHERN TRUST CORP | 230K | $642K | -4.0% | 0.599% | 0.00% |
| 6 | CITADEL ADVISORS LLC | 209K | $584K | — | 0.545% | 0.00% |
| 7 | BlackRock, Inc. | 197K | $550K | -1.7% | 0.513% | 0.00% |
| 8 | TWO SIGMA INVESTMENTS, LP | 197K | $549K | +41.4% | 0.512% | 0.00% |
| 9 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 182K | $509K | 0.0% | 0.475% | 0.01% |
| 10 | VANGUARD FIDUCIARY TRUST CO | 143K | $398K | — | 0.371% | 0.00% |
| 11 | Kestra Advisory Services, LLC | 130K | $362K | -26.1% | 0.338% | 0.00% |
| 12 | HB Wealth Management, LLC | 120K | $335K | 0.0% | 0.313% | 0.00% |
| 13 | Sculptor Capital LP | 104K | $290K | -75.3% | 0.271% | 0.00% |
| 14 | STATE STREET CORP | 102K | $283K | +31.5% | 0.265% | 0.00% |
| 15 | RENAISSANCE TECHNOLOGIES LLC | 100K | $278K | +22.8% | 0.259% | 0.00% |
| 16 | XTX Topco Ltd | 76K | $212K | +427.0% | 0.198% | 0.00% |
| 17 | 180 WEALTH ADVISORS, LLC | 64K | $178K | -15.9% | 0.166% | 0.02% |
| 18 | SIMPLEX TRADING, LLC | 58K | $163K | — | 0.152% | 0.01% |
| 19 | PANAGORA ASSET MANAGEMENT INC | 57K | $158K | 0.0% | 0.147% | 0.00% |
| 20 | Integrated Wealth Concepts LLC | 45K | $126K | -11.4% | 0.118% | 0.00% |
| 21 | JANE STREET GROUP, LLC | 41K | $114K | -62.5% | 0.107% | 0.00% |
| 22 | PFG Investments, LLC | 37K | $102K | +5.2% | 0.095% | 0.00% |
| 23 | RSM US WEALTH MANAGEMENT LLC | 36K | $101K | 0.0% | 0.094% | 0.00% |
| 24 | TWO SIGMA SECURITIES, LLC | 25K | $69K | — | 0.064% | 0.01% |
| 25 | Summit Financial, LLC | 21K | $58K | -95.3% | 0.054% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in FBIO — a direct measure of their conviction.
Filings activity in FBIO during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 50 | 2.0% | 13.41% | 7.34 pp | $14M | 35% |
| Q4 2025 | 51 | 7.3% | 20.75% | +5.79 pp | $22M | +39% |
| Q3 2025 | 55 | +12% | 14.96% | +7.41 pp | $16M | +98% |
| Q2 2025 | 49 | +8.9% | 7.55% | +3.12 pp | $8M | +70% |
| Q1 2025 | 45 | 15% | 4.43% | 1.56 pp | $5M | 26% |
| Q4 2024 | 53 | +8.2% | 5.99% | +1.87 pp | $6M | +46% |
| Q3 2024 | 49 | +0.0% | 4.12% | 0.46 pp | $4M | 10% |
| Q2 2024 | 49 | — | 4.58% | — | $5M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying FBIO stock.
Based on Q1 2026 13F filings, institutional ownership of Fortress Biotech, Inc. stands at 13.4%, held across 50 reporting institutions.
Opaleye Management Inc. is the largest reported institutional holder of FBIO, with approximately 1,042,000 shares worth $0.00B as of Q1 2026.
Yes — 6 widely-followed marquee investors appear among the top 25 institutional holders of FBIO, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC, TWO SIGMA INVESTMENTS, LP, RENAISSANCE TECHNOLOGIES LLC, JANE STREET GROUP, LLC.
Our composite Smart Money Score for FBIO is 52 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
13 institutions opened new positions in FBIO during Q1 2026, while 14 fully exited. 7 added to existing positions and 30 trimmed.
FBIO institutional ownership fell by 7.34 percentage points quarter-over-quarter, with a net change of -1 holders.
The top 10 institutions account for 77.5% of all reported 13F value in FBIO, and the top 25 account for 97.3%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Fortress Biotech, Inc. (FBIO) Institutional Ownership