Revenue remains highly erratic with a 45.1% contraction in 2026Q1, while persistent R&D spending consistently drives operating losses near $20 million per quarter.
| Sales/Revenue | 28.22M | 30.91M | 22.6M | 34.16M | 19.23M | 1.32M | 430K | 0 | 0 |
| Revenue Growth % | 20.08% | 36.75% | -33.83% | 77.63% | 1357.77% | 206.74% | - | - | - |
| Cost of Goods Sold | 21.94M | 3.33M | 0 | 0 | 0 | 0 | 57.72M | 1.79M | 379K |
| COGS % of Revenue | - | 10.78% | - | - | - | - | 13422.09% | - | - |
| Gross Profit | 6.28M | 27.58M | 22.6M | 34.16M | 19.23M | 1.32M | -57.28M | -1.79M | -379K |
| Gross Margin % | 22.26% | 89.22% | 100% | 100% | 100% | 100% | -13322.09% | - | - |
| Gross Profit Growth % | - | 22.01% | -33.83% | 77.63% | 1357.77% | 102.3% | -3094.92% | -373.09% | - |
| Operating Expenses | 87.05M | 109.68M | 125.28M | 142.06M | 136.37M | 102.05M | 11.25M | 49.29M | 26.05M |
| OpEx % of Revenue | - | 354.86% | 554.31% | 415.93% | 709.2% | 7737.15% | 2615.35% | - | - |
| Selling, General & Admin | 26.89M | 27.55M | 28.36M | 32.37M | 30.75M | 21.73M | 11.25M | 4.93M | 4.82M |
| SG&A % of Revenue | - | 89.13% | 125.47% | 94.78% | 159.91% | 1647.31% | 2615.35% | - | - |
| Research & Development | 82.1M | 85.47M | 94.53M | 109.69M | 105.62M | 80.33M | 57.72M | 44.36M | 21.23M |
| R&D % of Revenue | - | 276.51% | 418.23% | 321.15% | 549.29% | 6089.84% | 13422.09% | - | - |
| Other Operating Expenses | -2.24M | -3.33M | 2.4M | 0 | 0 | 0 | -57.72M | 0 | 0 |
| Operating Income | -80.77M | -82.11M | -102.68M | -107.91M | -117.14M | -100.73M | -68.53M | -51.08M | -26.05M |
| Operating Margin % | -286.16% | -265.64% | -454.31% | -315.93% | -609.2% | -7637.15% | -15937.44% | - | - |
| Operating Income Growth % | - | 20.04% | 4.84% | 7.88% | -16.28% | -46.99% | -34.15% | -96.11% | - |
| EBITDA | -77.97M | -78.78M | -99.56M | -104.45M | -113.82M | -97.51M | -67.2M | -49.29M | -25.67M |
| EBITDA Margin % | -276.27% | -254.86% | -440.51% | -305.83% | -591.93% | -7392.49% | -15628.84% | - | - |
| EBITDA Growth % | 17.3% | 20.88% | 4.68% | 8.22% | -16.73% | -45.09% | -36.34% | -92.02% | - |
| D&A (Non-Cash Add-back) | 2.79M | 3.33M | 3.12M | 3.45M | 3.32M | 3.23M | 1.33M | 1.79M | 379K |
| EBIT | -74.95M | -82.11M | -100.28M | -107.91M | -117.14M | -99.41M | -68.53M | -50.59M | -25.97M |
| Net Interest Income | 7.79M | 8.74M | 11.9M | 10.88M | 5.67M | -1.85M | 22K | -45K | -258K |
| Interest Income | 7.79M | 8.74M | 11.9M | 10.88M | 5.67M | 59K | 1M | 495K | 113K |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 1.91M | 979K | 540K | 371K |
| Other Income/Expense | 5.44M | 7.82M | 16.06M | 13.71M | 8.26M | -586K | -269K | -44K | -288K |
| Pretax Income | -75.32M | -74.28M | -86.62M | -94.2M | -108.88M | -101.32M | -68.8M | -51.13M | -26.34M |
| Pretax Margin % | -266.88% | -240.33% | -383.24% | -275.8% | -566.27% | -7681.58% | -16000% | - | - |
| Income Tax | 0 | 0 | 0 | 4.23M | 0 | 0 | 0 | 0 | 83K |
| Effective Tax Rate % | 0% | 0% | 0% | -4.49% | 0% | 0% | 0% | 0% | -0.32% |
| Net Income | -75.32M | -74.28M | -86.62M | -98.43M | -108.88M | -101.32M | -68.8M | -51.13M | -26.34M |
| Net Margin % | -266.88% | -240.33% | -383.24% | -288.17% | -566.27% | -7681.58% | -16000% | - | - |
| Net Income Growth % | 6.36% | 14.24% | 11.99% | 9.6% | -7.46% | -47.27% | -34.56% | -94.13% | - |
| Net Income (Continuing) | -75.32M | -74.28M | -86.62M | -98.43M | -108.88M | -101.32M | -68.8M | -51.13M | -26.34M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -1.08 | -1.18 | -1.58 | -2.34 | -2.62 | -2.78 | -1.90 | -1.40 | -1.34 |
| EPS Growth % | 14.6% | 25.32% | 32.48% | 10.69% | 5.76% | -46.32% | -35.71% | -4.48% | - |
| EPS (Basic) | - | -1.18 | -1.58 | -2.34 | -2.62 | -2.78 | -1.90 | -1.40 | -1.34 |
| Diluted Shares Outstanding | 69.54M | 62.98M | 54.9M | 41.97M | 41.59M | 37.17M | 36.79M | 36.82M | 19.63M |
| Basic Shares Outstanding | 69.54M | 62.98M | 54.9M | 41.97M | 41.59M | 37.17M | 36.79M | 36.82M | 19.63M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
Clinical milestone dependency
As evidenced by the quarterly financial data, FHTX's revenue trajectory remains highly erratic, characterized by a 45.1% contraction in 2026Q1 following previous periods of growth, reflecting the inherent unpredictability of milestone-based payments from pharmaceutical partners rather than consistent, organic commercial demand for its chromatin-regulatory platform.
The reliance on non-recurring collaboration revenue creates significant quarter-over-quarter variance that complicates long-term forecasting. Investors should interpret these fluctuations as indicators of partnership progress rather than underlying business health, as the absence of commercial product sales leaves the top line entirely exposed to the timing of research milestones.
Based on reported income statements, FHTX maintains a rigid cost structure dominated by R&D expenditures, which consistently exceeded $20 million per quarter throughout 2025, highlighting the substantial capital requirements necessary to sustain the company's proprietary Gene Traffic Control platform and ongoing clinical development programs.
The company's expense discipline appears secondary to the necessity of advancing its clinical pipeline, as R&D spending remains largely decoupled from the volatility of partnership revenue. This structural commitment to high-burn research suggests that management is prioritizing long-term asset validation over short-term operating efficiency.
According to the provided financial filings, FHTX exhibits a negative operating margin profile, with operating losses consistently hovering near $20 million per quarter, indicating that the company has yet to achieve the scale required to leverage its fixed operating costs against its current collaboration-based revenue streams.
The lack of operating leverage is a hallmark of the current clinical-stage business model, where SG&A and R&D costs are fixed relative to the lumpy nature of milestone income. Without a transition to commercial-stage revenue, the company remains structurally incapable of scaling profitability, leaving it vulnerable to continued operating losses.
As noted in the financial data, the company's reliance on external partnership payments to offset massive operating deficits warrants skepticism, particularly given that the 2025Q3 gross margin turned negative, suggesting that the underlying economics of these collaborations may be more complex and costly than headline revenue figures imply.
Short-term observers might focus on the high gross margins in other quarters, but the 2025Q3 anomaly suggests that direct costs associated with research collaborations can spike unexpectedly. This volatility, combined with a high burn rate, raises questions about the long-term viability of the current funding model if clinical milestones are delayed.
Quick answers to the most common questions about buying FHTX stock.
For fiscal year 2025, Foghorn Therapeutics Inc. (FHTX) reported total revenue of $30.9M.
Foghorn Therapeutics Inc. (FHTX) reported a net loss of $74.3M for the fiscal year ending 2025.
Foghorn Therapeutics Inc. (FHTX) reported an operating income of $-82.1M, resulting in an operating profit margin of -265.6%. This margin reflects the operational efficiency of the business before interest and taxes.
Foghorn Therapeutics Inc. (FHTX) generated $27.6M in gross profit for the year, representing a gross profit margin of 89.2%. This demonstrates the company's core pricing power and production efficiency.