Last 47 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
Galapagos N.V.'s quarterly P/E stands at 0.7x, down 97.1% year-over-year — suggesting improving earnings relative to price.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | 5.88 | 0.70 | — | — | — | 23.71 | — | 44.25 | 5.88 | — | 22.15 | 131.33 | 27.60 |
| — | -97.1% | — | — | — | — | — | -66.3% | -78.7% | — | -31.4% | — | — | |
| P/S Ratio | 1.69 | 0.60 | 8.02 | 7.06 | 5.51 | 6.09 | 7.93 | 5.24 | 8.50 | — | 4.74 | 4.47 | 10.87 |
| — | -90.2% | +1.1% | +34.6% | -35.1% | — | +67.2% | +17.4% | -21.8% | — | -8.0% | -33.0% | +43.6% | |
| P/B Ratio | 0.58 | 0.67 | 0.79 | 0.70 | 0.60 | 0.63 | 0.66 | 0.56 | 0.73 | 0.96 | 0.87 | 1.04 | 0.99 |
| — | +5.0% | +19.7% | +24.2% | -17.9% | -33.9% | -23.6% | -45.9% | -26.2% | -17.0% | -16.8% | -25.2% | -36.3% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | 3.72 | 0.70 | — | — | — | — | — | 6.52 | 22.17 | — | 17.87 | 38.27 | — |
| — | — | — | — | — | — | — | -83.0% | — | — | — | — | — | |
| EV / EBIT | 4.00 | 0.70 | — | — | — | — | — | 6.52 | 22.17 | — | 17.87 | 38.27 | — |
| — | — | — | — | — | — | — | -83.0% | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Galapagos N.V.'s operating margin was 82.3% in Q4 2025, up 428.6 pp QoQ and up 165.4 pp YoY. The trailing four-quarter average of -140.8% lags the current quarter, suggesting the recent improvement is above-trend. Gross margin expanded 198.7% YoY, indicating pricing power or improving input costs.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 56.0% | 49.0% | 84.8% | 92.8% | 81.7% | -49.6% | 100.0% | 78.7% | 95.9% | 100.0% | 95.3% | 97.2% | 100.0% |
| — | +198.7% | -15.2% | +17.8% | -14.8% | -149.6% | +5.0% | -19.0% | -4.1% | +4.6% | +573.6% | -1.0% | +306.8% | |
| Operating Margin | 40.6% | 82.3% | -346.3% | -87.3% | -211.7% | -83.1% | -90.7% | -49.0% | -53.1% | 33.1% | -25.2% | -7.1% | -24.2% |
| — | +199.1% | -281.6% | -78.2% | -298.9% | -350.7% | -260.2% | -587.8% | -118.9% | +123.8% | +8.7% | +87.1% | -56.3% | |
| Net Margin | 28.9% | 86.8% | -284.0% | -162.0% | -204.6% | 33.5% | -84.3% | 11.5% | 144.5% | -75.3% | 21.5% | 3.4% | 39.6% |
| — | +159.0% | -237.1% | -1503.8% | -241.6% | +144.5% | -491.5% | +239.2% | +264.7% | +65.4% | +36.0% | +124.6% | +505.9% |
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 10.5% | 25.6% | -7.3% | -3.9% | -5.4% | 0.9% | -1.7% | 0.3% | 3.2% | 5.8% | 1.0% | 0.2% | 0.9% |
| — | +2813.5% | -319.2% | -1367.4% | -271.4% | -84.9% | -276.0% | +56.2% | +247.8% | +173.2% | +22.9% | +127.6% | +281.2% | |
| ROA | 8.5% | 20.8% | -5.1% | -2.7% | -3.8% | 0.6% | -1.2% | 0.2% | 2.1% | 3.6% | 0.6% | 0.1% | 0.5% |
| — | +3309.4% | -326.9% | -1398.8% | -281.7% | -83.0% | -307.0% | +86.4% | +317.7% | +183.8% | +33.7% | +129.7% | +291.6% | |
| ROIC | 11.3% | 18.6% | -6.9% | -1.6% | -4.3% | -1.7% | -1.4% | -1.0% | -0.9% | -2.0% | -0.9% | -0.3% | -0.5% |
| — | +1221.8% | -377.2% | -62.1% | -376.7% | +18.3% | -57.8% | -211.9% | -91.9% | +58.3% | +39.6% | +91.2% | +72.3% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
Galapagos N.V.'s Debt/EBITDA ratio is 0.0x — comfortably within a safe range. The current ratio has improved 102.1% YoY to 20.15x, strengthening the short-term liquidity position.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | 0.01 |
| — | -7.6% | -23.4% | -14.5% | +43.4% | +17.9% | -25.8% | -37.4% | -55.8% | -60.4% | -36.0% | -34.4% | -34.9% | |
| Debt / EBITDA | 0.02 | 0.02 | — | — | — | — | — | 0.18 | 0.34 | — | 0.47 | 0.91 | — |
| — | — | — | — | — | — | — | -80.2% | — | — | — | — | — | |
| Current Ratio | 20.15 | 20.15 | 8.63 | 8.08 | 7.95 | 9.97 | 10.13 | 10.05 | 9.91 | 9.02 | 8.91 | 8.49 | 7.95 |
| — | +102.1% | -14.9% | -19.6% | -19.8% | +10.5% | +13.7% | +18.4% | +24.7% | +11.2% | +6.3% | +3.1% | -5.8% | |
| Quick Ratio | 20.15 | 20.15 | 8.56 | 7.99 | 7.86 | 9.81 | 9.95 | 9.87 | 9.70 | 8.84 | 8.78 | 8.38 | 7.85 |
| — | +105.3% | -13.9% | -19.0% | -19.0% | +10.9% | +13.2% | +17.8% | +23.6% | +10.5% | +5.4% | +2.5% | -6.7% | |
| Interest Coverage | 164.04 | 897.41 | -10.48 | — | -203.47 | — | -197.47 | -133.97 | -130.44 | — | -105.67 | -13.67 | -16.82 |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 47 years · Updated daily
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Start ComparisonGalapagos N.V.'s current P/E is 5.9x. The average P/E over the last 1 quarters is 0.7x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Galapagos N.V.'s current operating margin is 40.6%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Galapagos N.V.'s business trajectory between earnings reports.