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GPCRStructure Therapeutics Inc.
$45.51$2.6B
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HomeStocksGPCRP/E History

GPCR logoStructure Therapeutics Inc. (GPCR) P/E Ratio History

Insufficient Data

Insufficient historical P/E data to classify valuation. · Data 2026–2026

Current P/E (TTM)
-19.0x
5Y Avg P/E
N/A
Median N/A
5Y Percentile
N/A
PEG Ratio
N/A
TTM EPS$-2.35
Price$45.51
Earnings YieldN/A
EPS Growth (1Y)-2.6%
EPS Growth (5Y)N/A

Loading P/E history...

P/E Ratio Analysis

As of June 23, 2026, Structure Therapeutics Inc. (GPCR) trades at a price-to-earnings ratio of -19.0x, with a stock price of $45.51 and trailing twelve-month earnings per share of $-2.35.

Compared to the Healthcare sector median P/E of 22.1x, GPCR trades at a 186% discount to its sector peers. The sector includes 233 companies with P/E ratios ranging from 0.0x to 194.5x.

Relative to the broader market, GPCR trades at a notable discount to the S&P 500 median P/E of 24.3x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.

For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our GPCR DCF Valuation Calculator →

Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.

GPCR Cross-Benchmark Valuation

How does the current P/E compare to sector peers and the broader market?

vs. Healthcare
-19.0vs22.1
-186%
Below Sector
vs. S&P 500
-19.0vs24.3
-178%
Below Market
PEG Analysis
N/A
P/E ÷ EPS Growth
Based on -3% EPS growth (1Y)

GPCR P/E vs Peers

Metabolic and Obesity Therapies peers sorted by market cap

CompanyMarket CapP/E RatioPEG RatioEPS Growth (1Y)
NVO logoNVONovo Nordisk A/S
$204B13.0Lowest0.59Best+2%
LLY logoLLYEli Lilly and Company
$1.0T48.11.66+96%Best

Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.

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GPCR — Frequently Asked Questions

Quick answers to the most common questions about buying GPCR stock.

What is GPCR's P/E ratio?

Structure Therapeutics Inc. (GPCR) trailing twelve-month P/E ratio is -19.0x, based on TTM diluted EPS of $-2.35. The 5-year average P/E is N/A and the historical range spans N/A to N/A.

Is GPCR stock overvalued or undervalued?

GPCR current P/E: -19.0x. 5-year average P/E: N/A. Percentile: N/A.

Is GPCR stock expensive?

GPCR is fairly valued relative to its own history. The current P/E of -19.0x is near the 5-year average of N/A (N/A percentile of historical range).

What is GPCR's historical P/E range?

Over the past 5 years, GPCR's P/E ratio has ranged from N/A to N/A, with a median of N/A and an average of N/A. The current P/E of -19.0x places the stock at the N/A percentile of this range. Full historical data spans 2026–2026.

How does GPCR's P/E compare to the S&P 500?

GPCR trades at -19.0x P/E versus the S&P 500 median of 24.3x. The 178% discount to the market suggests lower growth expectations or perceived higher risk.

How does GPCR's valuation compare to Healthcare peers?

Structure Therapeutics Inc. P/E of -19.0x compares to the Healthcare sector median of 22.1x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.

What is GPCR's PEG ratio?

GPCR PEG ratio is N/A, based on a P/E of -19.0x and EPS growth of -2.6%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.

What is GPCR's earnings yield?

GPCR earnings yield is N/A, the inverse of its -19.0x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.

GPCR P/E Ratio History

Quarterly valuation multiple from closing price and trailing EPS

Current-
Period Avg-
Range- - -
Change-
0 quarters- - -